Investigation in blood-brain barrier integrity and susceptibility to immune cell penetration in a mouse model of Dravet syndrome by Cristina Alonso, Alicia García-Culebras, Valentina Satta, Inés Hernández-Fisac, Álvaro Sierra, José A. Guimaré, Ignacio Lizasoain, Javier Fernández-Ruiz, Onintza Sagredo

“…However, the levels of endogenous IgG in this brain structure were significantly elevated in DS mice compared to controls, directly indicating the occurrence of extravasation into the brain parenchyma and indirectly that the BBB in DS mice may be relatively affected, a fact confirmed by the reduction in the levels of BBB-related proteins such as ZO-1 in these mice. …”
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A regulatory mutant on TRIM26 conferring the risk of nasopharyngeal carcinoma by inducing low immune response by Xiao‐Ming Lyu, Xiao‐Wei Zhu, Manli Zhao, Xian‐Bo Zuo, Zhong‐Xi Huang, Xiao Liu, Tao Jiang, Xue‐Xi Yang, Xin Li, Xiao‐Bing Long, Jian‐Guo Wang, Jin‐Bang Li, Ming‐Yu Han, Shuang Wang, Teng‐Fei Liu, Bo Zhang, Tao Sun, Zhi Cheng, Mo‐Chang Qiu, Lei Dong, Lu Zheng, Long‐Cheng Zhang, Jia‐Hong Wang, Gan‐Guan Wei, Kaitai Yao, Qian Wang, Hou‐Feng Zheng, Xin Li

“…Abstract The major histocompatibility complex (MHC) is most closely associated with nasopharyngeal carcinoma (NPC), but the complexity of its genome structure has proven challenging for the discovery of causal MHC loci or genes. …”
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Mapping the Filamentary Nebula of NGC 1275 with Multiwavelength SITELLE Observations by Carter Lee Rhea, Julie Hlavacek-Larrondo, Marie-Lou Gendron-Marsolais, Benjamin Vigneron, Megan Donahue, Auriane Thilloy, Laurie Rousseau-Nepton, Mar Mezcua, Norbert Werner, Jorge Barrera-Ballesteros, Hyunseop Choi, Alastair Edge, Andrew Fabian, G. Mark Voit

“…The filamentary nebula encompassing the central galaxy of the Perseus Cluster, NGC 1275, is a complex structure extending dozens of kiloparsecs from NGC 1275. …”
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Social networks, environmental, and individual factors associated with COVID-19 vaccination and booster uptake– The prospective PRIME cohort study by Céline J.A. van Bilsen, Lisanne C.J. Steijvers, Stephanie Wagner, Demi M.E. Pagen, Senne M.C.E. Wijnen, Kevin Konings, Christian J.P.A. Hoebe, Annemarie Koster, Nicole H.T.M. Dukers-Muijrers

“…Methods: In the PRIME longitudinal cohort study, we used online questionnaires to collect baseline data at the end of 2021, including participants' COVID-19 vaccination status and various factors, i.e., structural and functional social network characteristics (interpersonal factors), societal (social and physical living environment) community (work and social participation), and individual (sociodemographics, health) factors. …”
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Fertility intentions among Chinese adults: a cross-sectional study using a national survey by Mingyan Hao, Chenxiao Zhang, Haofeng Fu, Jingting Zhang, Ziyi Zhang, Baotong Ma, Ruitong Xia, Yuanwei Lu, Jingwen Liu, Hanjia Xin, Yumeng Cao, Saier Yang, Runqing Li, Ji Zhao, Jin Zhang, Zheng Gao, Yaxin Zeng, Yixiao Ding, Zhuolun Ren, Yan Guan, Na Zhang, Jia Li, Yan Ma, Pei Wei, Jingjing Dong, Chen Chen, Yajing Zhou, Jianzhong Zheng, Wei Liu, Lizheng Wang

“…Methods In our research, we performed a cross-sectional analysis using data gathered in 2022 from the Psychology and Behavior Investigation of Chinese Residents (PBICR), which encompassed 21,916 participants aged 18 to 49 years. …”
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Cation disordering in ankerite as a function of Fe content by A. Zucchini, M. Masotta, M. Nazzari, M. Fastelli, P. Comodi

“…Crystal structure refinements, using single-crystal X-ray diffraction data, indicate that the temperature of the order–disorder phase transition in ankerite, when the space group changes from <span class="inline-formula"><math xmlns="http://www.w3.org/1998/Math/MathML" id="M7" display="inline" overflow="scroll" dspmath="mathml"><mrow><mi>R</mi><mover accent="true"><mn mathvariant="normal">3</mn><mo mathvariant="normal">¯</mo></mover></mrow></math><span><svg:svg xmlns:svg="http://www.w3.org/2000/svg" width="17pt" height="12pt" class="svg-formula" dspmath="mathimg" md5hash="f75e6c667c3f64f21a65bfc83826b4ad"><svg:image xmlns:xlink="http://www.w3.org/1999/xlink" xlink:href="ejm-37-577-2025-ie00003.svg" width="17pt" height="12pt" src="ejm-37-577-2025-ie00003.png"/></svg:svg></span></span> to <span class="inline-formula"><math xmlns="http://www.w3.org/1998/Math/MathML" id="M8" display="inline" overflow="scroll" dspmath="mathml"><mrow><mi>R</mi><mover accent="true"><mn mathvariant="normal">3</mn><mo mathvariant="normal">¯</mo></mover><mi>c</mi></mrow></math><span><svg:svg xmlns:svg="http://www.w3.org/2000/svg" width="23pt" height="12pt" class="svg-formula" dspmath="mathimg" md5hash="fe064a2c9801a78cad20978a78c22cc9"><svg:image xmlns:xlink="http://www.w3.org/1999/xlink" xlink:href="ejm-37-577-2025-ie00004.svg" width="23pt" height="12pt" src="ejm-37-577-2025-ie00004.png"/></svg:svg></span></span>, is significantly influenced by the amount of Fe in the mineral's crystal structure, being full disordering conditions attained at 1000 and 800 °C in ankerites with <span class="inline-formula"><i>x</i>=0.3</span> and <span class="inline-formula"><i>x</i>=0.7</span>, respectively. …”
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Building a collaborative ecosystem across the IDeA-CTR networks in response to a public health emergency by A. Jerrod Anzalone, Sharon Patrick, Amber Abel, Brad Price, Elizabeth Reisher, Kent Ripplinger, Mary Emmett, Ronald Horswell, San Chu, William B. Hillegass, Francisco S. Sy, Brian Melancon, H. Timothy Bunnell, Lucio Miele, Mary Helen Mays, Joseph Keawe‘aimoku Kaholokula, Elizabeth S. Chen, Karen M. Crowley, Indra Neil Sarkar, Susan L. Santangelo, Clifford J. Rosen, Jeremy Harper, David Bard, William Beasley, Sally L. Hodder

“…Methods: We developed an organizational structure across the IDeA-CTRs to improve research productivity in resource-challenged areas of the U.S. …”
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Senescence-induced p21high macrophages contributed to CD8+ T cells-related immune hyporesponsiveness in kidney transplantation via Zfp36/IL-27 axis by Tingting Zhu, Qixia Shen, Lingling Shen, Yucheng Wang, Bochen Zhu, Lifeng Ma, Shi Feng, Cuili Wang, Sijing Yan, Jingyi Li, Zhimin Chen, Jingyi Zhou, Hongfeng Huang, Bingjue Li, Zhouji Shen, Qian Wang, Jianwei Wang, Wilfried Gwinner, Irina Scheffner, Song Rong, Bing Yang, Junwen Wang, Hermann Haller, Xiaoping Han, Guoji Guo, Zhinan Yin, Jin Jin, Hui-Yao Lan, Jianghua Chen, Hong Jiang

“…Age-related functional and structural changes in the immune system have been observed, yet the precise influence of aged immunity on kidney transplant remains unclear. …”
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New psychoactive substances (NPS) identified in Canada: Results of the online NPS survey (2020–2023) by Sophie Rymill, Lexy Candler, Pavitra Ramachandran, Chantal Bacev-Giles, Raymond-Jonas Ngendabanka, Stephane Racine, Nancy He, Michelle Ross, Susantha Mohottalage

“…Unwanted health effects were reported in over 50 % of cases. Conclusions: Structural trends amongst reported NPS were analysed, with a focus on hallucinogens of the tryptamine, lysergamide, and phenethylamine chemical classes. …”
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Spatiotemporal variability in the feeding habits of anchovy and sardine: a comparison of upwelling and river-runoff driven ecosystems by Paola Rumolo, Marco Barra, Angelo Bonanno, Simona Altieri, Rosalia Ferreri, Antonella Gargano, Gualtiero Basilone, Serena Gherardi, Simona Genovese, Maria Rosa Di Cicco, Carmine Lubritto

“…However, local factors—such as environmental conditions, human activities, coastal pollution, and more generally, climate change have had a significant impact on their trophic interactions, affecting the energy flow, structure, and function of the marine ecosystems in which they live. …”
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Influence of Starvation on Biochemical, Physiological, Morphological, and Transcriptional Responses Associated with Glucose and Lipid Metabolism in the Liver of Javelin Goby (<i>Sy... by Xiangyu Cui, Xiaoyang Huang, Xiangning Chen, Honghui Li, Yanru Wu, Zikui Yang, Zhiyu Liu, Rui Feng, Jianhe Xu, Chaoqing Wei, Zhujin Ding, Hanliang Cheng

“…Overall, starvation lasting 7 days or more could concurrently mobilize hepatic carbohydrates and fat as energy resources and diminished their hepatic accumulation by suppressing biosynthesis and enhancing catabolism and transport, ultimately metabolically and structurally perturbing the liver in <i>S. hasta</i>. …”
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Social vulnerability and genetic service utilization among unaffected BRIDGE trial patients with inherited cancer susceptibility by Jemar R. Bather, Melody S. Goodman, Adrian Harris, Guilherme Del Fiol, Rachel Hess, David W. Wetter, Daniel Chavez-Yenter, Lingzi Zhong, Lauren Kaiser-Jackson, Rachelle Chambers, Richard Bradshaw, Wendy Kohlmann, Sarah Colonna, Whitney Espinel, Rachel Monahan, Saundra S. Buys, Ophira Ginsburg, Kensaku Kawamoto, Kimberly A. Kaphingst, on behalf of the BRIDGE research team

“…Existing and future cohort studies can incorporate census data to derive analytic insights for clinical scientists. …”
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Longitudinal analysis of lifestyle risk factors, nutrition status and drivers of food choice among urban migrants in Ulaanbaatar, Mongolia, and Almaty, Kazakhstan: a formative stud... by Sabri Bromage, Shamil Tazhibayev, Xin Zhou, Chang Liu, Enkhtsetseg Tserenkhuu, Oksana Dolmatova, Munkhbat Khishignemekh, Leyla Musurepova, Wusigale, Soninkhishig Tsolmon, Enkhjargal Tsendjav, Davaasambuu Enkhmaa, Rajesh Kumar Rai, Bayarmaa Enkhbat, Bilige Menghe, Davaasambuu Ganmaa

“…Design: We collected panel data on household structure, drivers of food choice, nutrition knowledge and diverse measures of nutrition status and lifestyle risk from urban migrants at 0, 3, 6 and 9 months using harmonised methodology in two cities. …”
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Two novel plasmids harbouring the multiresistance gene cfr in porcine Staphylococcus equorum by Ning Xie, Tengfei Ma, Yuan Gao, Jiani Fu, Chune Tan, Zheng Wang, Zhuo Wang, Henrike Krüger-Haker, Andrea T. Feßler, Congming Wu, Jianzhong Shen, Stefan Schwarz, Yang Wang

“…These two plasmids exhibited low structural similarities to the so far reported cfr-carrying plasmids. …”
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Temperature Rise Characteristic of Circuit Breakers Based on New Environmentally Friendly Gas by Lihua ZHAO, Zhiyun WU, Zhiqiang YAN, Xiaolong HUANG, Wenjun NING, Shenli JIA

“…The arrangement of temperature sensors and the testing scheme are established, providing a data foundation for further studies on temperature rise characteristics. …”
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RAD-Seq-derived SSR markers: a new paradigm for genetic analysis and construction of genetically improved production populations in Pinus koraiensis by Pingyu Yan, Wanying Zhang, Junfei Hao, Xiaotian Miao, Jun Wu, Zixiong Xie, Zhixin Li, Lei Zhang, Hanguo Zhang

“…The SSR markers were subsequently employed to examine the genetic diversity and structure of the plus tree population. The genetic data were then integrated with multiyear cone production records from the population of plus trees, thus facilitating the construction of a production population. …”
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Leave as Fast as You Can: Using Generative AI to Automate and Accelerate Hospital Discharge Reports by Alex Trejo Omeñaca, Esteve Llargués Rocabruna, Jonny Sloan, Michelle Catta-Preta, Jan Ferrer i Picó, Julio Cesar Alfaro Alvarez, Toni Alonso Solis, Eloy Lloveras Gil, Xavier Serrano Vinaixa, Daniela Velasquez Villegas, Ramon Romeu Garcia, Carles Rubies Feijoo, Josep Maria Monguet i Fierro, Beatriu Bayes Genis

“…Future work should refine specialty-specific prompts to curb omissions, add temporal consistency checks to prevent outdated data propagation, and validate time savings and clinical impact in multi-center trials.…”
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Social media marketing and brand loyalty: exploring interrelationships through symmetrical and asymmetrical modeling by Faizan Ali, Chokechai Suveatwatanakul, Luana Nanu, Murad Ali, Abraham Terrah

“…Design/methodology/approach – A total of 402 valid responses were collected from Amazon MTurk, and the data were subjected to partial least squares structural equation modeling and fuzzy-set qualitative comparative analysis (fsQCA). …”
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Microcephaly protein ANKLE2 promotes Zika virus replication by Adam T. Fishburn, Cole J. Florio, Thomas N. Klaessens, Brian Prince, Neil A. B. Adia, Nicholas J. Lopez, Nitin Sai Beesabathuni, Sydney S. Becker, Liubov Cherkashchenko, Sophia T. Haggard Arcé, Vivian Hoang, Traci N. Shiu, R. Blake Richardson, Matthew J. Evans, Claudia Rückert, Priya S. Shah

“…We previously mapped ZIKV-host protein interactions and identified the interaction between ZIKV non-structural protein 4A (NS4A) and host microcephaly protein ankyrin repeat and LEM domain-containing 2 (ANKLE2). …”
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Physical and Mechanical Properties of Green Cementless Mortar Incorporating Waste Paper Sludge Ash by Aida Nabila Jamaluddin, Siti Asmahani Saad, Siti Aliyyah Masjuki, Wan Nur Firdaus Wan Hassan, Siti Noratikah Che Deraman, Nadiah Md Husain

“…Furthermore, Fourier-transformed infrared spectroscopy (FTIR) was conducted to ascertain the structural elucidation and scanning electron microscope (SEM) analysis was done to provide microstructural observations of the geopolymer. …”
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