Specific inhibition of fibroblast growth factor receptor 1 signaling by a DNA aptamer by Vladimira Zlinska, Zuzana Feketova, Aleksandra Czyrek, Julia Chudzian, Martina Lenarcic Zivkovic, Vlad-Constantin Ursachi, Pooja Dudeja, Bohumil Fafilek, Jan Rynes, Gustavo Rico-Llanos, Adolf Koudelka, Tanaya Roy, Martyna Biadun, Vendula Raskova, Katerina Svozilova, Michaela Stroblova, Mateusz Krzyscik, Kalina Hristova, Daniel Krowarsch, Silvie Foldynova-Trantirkova, Malgorzata Zakrzewska, Lukas Trantirek, Pavel Krejci

“…We show that the VZ23 inhibits FGFR1 signaling in the presence of cognate fibroblast growth factor (FGF) ligands and its inhibitory activity is linked to its capacity to form unusual G-quadruplex structure. Our data suggest that targeting FGFR1 with DNA aptamers could be an effective alternative to TKIs for treating impaired FGFR1 signaling in human craniosynostoses.…”
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The changing face of the Arctic: four decades of greening and implications for tundra ecosystems by Gerald V. Frost, Uma S. Bhatt, Matthew J. Macander, Logan T. Berner, Donald A. Walker, Martha K. Raynolds, Rúna Í. Magnússon, Annett Bartsch, Jarle W. Bjerke, Jarle W. Bjerke, Howard E. Epstein, Bruce C. Forbes, Scott J. Goetz, Elizabeth E. Hoy, Elizabeth E. Hoy, Stein R. Karlsen, Timo Kumpula, Trevor C. Lantz, Mark J. Lara, Efrén López-Blanco, Paul M. Montesano, Paul M. Montesano, Christopher S. R. Neigh, Ingmar Nitze, Kathleen M. Orndahl, Taejin Park, Taejin Park, Gareth K. Phoenix, Adrian V. Rocha, Brendan M. Rogers, Gabriela Schaepman-Strub, Hans Tømmervik, Mariana Verdonen, Mariana Verdonen, Alexandra Veremeeva, Anna-Maria Virkkala, Christine F. Waigl

“…Nonetheless, long-term increases in NDVI—commonly known as “the greening of the Arctic”—remain prominent across large areas in all available long-term spaceborne datasets and align with long-term shifts in vegetation structure documented in disparate Arctic regions. Common shifts reported from the Low Arctic, such as shrubification, generally portend declines in floristic diversity, and shifts in fauna that favor boreal forest species. …”
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Features of the Circulation of ARVI Pathogens During of Emergence and Widespread of SARS-CoV-2 in the 2018–2021 by E. I. Burtseva, L. V. Kolobukhina, O. L. Voronina, A. V. Ignatjeva, E. A. Mukasheva, A. D. Panova, E. L. Feodoritova, K. G. Krasnoslodotsev, S. V. Trushakova, L. N. Merkulova, I. N. Khlopova, N. V. Breslav, N. N. Ryzhova, M. S. Kunda, E. I. Aksenova, R. V. Vartanyan, L. B. Kisteneva, O. A. Burgasova, A. G. Rosatkevich, I. S. Kruzhkova, M. V. Bazarova, S. V. Smetanina, N. A. Tsvetkova, Yu. S. Levochkina, M. V. Kozlova, D. O. Korostin, E. I. Botsmanov

“…To identify the features of the structure of ARVI during the emergence and widespread spread of SARS-CoV-2. …”
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Corporate Governance Code and Earnings Management by Azam Valizadeh Iarijani, Reyhaneh Iranpour

“…The results of the research based on regression analysis of panel data indicated that the new corporate governance code had a negative and significant impact on earning management based on the manipulation of accruals. …”
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The moderating effect of self-efficacy on the relationship between parents and children and academic participation, considering the mediating variable of learning adaptation among... by meysam karamipour, samaneh mataji, rezvaneh kazem nezhad, maryam esfandyari

“…Adaptability of learning Adaptation in school is a multi-dimensional structure that should be distinguished between several types, i.e. academic, social and individual emotional adaptation (Lavasani et al, 2018). …”
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Synthesizing the Academic Administrators’ Competencies: Developing of a Model by Homa Rahmani, Asadollah Khadivi

“…The technique of triangulation refers to the use of multiple sources of data to draw conclusions. Using multiple approaches in a study can lead to increasing the credibility of information. …”
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Proteogenomic annotation of T6SS components identified in Bacteroides fragilis secretome by Natalya B. Zakharzhevskaya, Olga Yu Shagaleeva, Daria A. Kashatnikova, Daria A. Kashatnikova, Anton O. Goncharov, Anton O. Goncharov, Daria V. Evsyutina, Dmitry A. Kardonsky, Elizaveta A. Vorobeva, Artemiy S. Silantiev, Viktoria D. Kazakova, Irina V. Kolesnikova, Ivan O. Butenko, Anna A. Vanyushkina, Svetlana V. Smirnova, Andrei V. Chaplin, Andrei V. Chaplin, Boris A. Efimov, Boris A. Efimov

“…Intensive study of the T6SS structure has led to an understanding of certain issues related to its functional activity, but the exact regulatory mechanisms of E-I protein pair activity remain unclear. …”
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The MaNGA Dwarf Galaxy Sample (MaNDala): Stellar Profiles and Gradients Characterization by M. Cano-Díaz, A. Rodríguez-Puebla, A. C. Robleto-Orús, V. Ávila-Reese, H. M. Hernández-Toledo, J. A. Vázquez-Mata, O. Valenzuela, J. J. González, H. J. Ibarra-Medel, J. C. Clemente-González, L. Pavón-Alvarez

“…We derived robust radial profiles and inner/outer gradients of various stellar population (SP) properties for a sample of 124 bright dwarf galaxies, 10 ^7.53 ≤ M _* / M _⊙ ≤ 10 ^9.06 , from the MaNDala sample, using integral field spectroscopy observations. Given the complex structure of dwarf galaxies, we explored four different methods to derive SP radial profiles: two based on concentric elliptical rings, and the other two exploiting the spatially resolved nature of the data. …”
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A Rare Case of Exophiala Dermatitidis Isolation in a Patient with Non-Cystic Fibrosis Bronchiectasis: Colonization or True Infection? by Francesco Rocco Bertuccio, Nicola Baio, Simone Montini, Valentina Ferroni, Vittorio Chino, Lucrezia Pisanu, Marianna Russo, Ilaria Giana, Elisabetta Gallo, Lorenzo Arlando, Klodjana Mucaj, Mitela Tafa, Maria Arminio, Emanuela De Stefano, Alessandro Cascina, Angelo Guido Corsico, Giulia Maria Stella, Valentina Conio

“…<b>Discussion:</b> This case underscores the diagnostic challenges in distinguishing fungal colonization from true infection in structurally abnormal lungs. In NCFB, disrupted mucociliary clearance and microbial dysbiosis may facilitate fungal persistence, even in the absence of overt immunosuppression. …”
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Possible Carbon Dioxide above the Thick Aerosols of GJ 1214 b by Everett Schlawin, Kazumasa Ohno, Taylor J. Bell, Matthew M. Murphy, Luis Welbanks, Thomas G. Beatty, Thomas P. Greene, Jonathan J. Fortney, Vivien Parmentier, Isaac R. Edelman, Samuel Gill, David R. Anderson, Peter J. Wheatley, Gregory W. Henry, Nishil Mehta, Laura Kreidberg, Marcia J. Rieke

“…Further modeling of the planet’s atmosphere, interior structure and origins will provide valuable insights about how sub-Neptunes like GJ 1214 b form and evolve.…”
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Nematodes exposed to furfural acetone exhibit a species-specific vacuolar H+-ATPase response by Wanli Cheng, Wei Dai, Wen Chen, Hua Xue, Zhengzheng Zhao, Zhengbing Jiang, Huanan Li, Jiashu Liu, Feng Huang, Minmin Cai, Longyu Zheng, Ziniu Yu, Donghai Peng, Jibin Zhang

“…And the Spearman analysis results illustrated that the differential nematicidal activity of FAc against various nematodes is attributed to variations in the sequence and structure of the receptor proteins VHA-12 and VHA-13 among different nematode species. …”
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Exploring the phylogenetic framework and trait evolution of Impatiens through chloroplast genome analysis by Wen-Xiang Lan, Qing Mo, Meng-Meng Jin, Yong-Hui Wen, Meng-Qing Yang, Hui Ma, Hai-Quan Huang, Mei-Juan Huang

“…The chloroplast genome of Impatiens exhibited a typical four-part structure, with lengths ranging from 146,987 bp(I. morsei)- 152,872 bp(I. jinpingensis). …”
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Mapping grey matter and cortical thickness alterations associated with subjective cognitive decline and mild cognitive impairment among rural-dwelling older adults in China: A popu... by Ziwei Chen, Qianqian Xie, Jiafeng Wang, Yan Wang, Huisi Zhang, Chunyan Li, Yongxiang Wang, Lin Cong, Shi Tang, Tingting Hou, Lin Song, Yifeng Du, Chengxuan Qiu

“…Background: The structural brain alterations for subjective cognitive decline (SCD) and mild cognitive impairment (MCI) are poorly defined. …”
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Dietary Solid-state-fermentation product of Bacillus velezensis T23 alleviate hepatic steatosis, oxidative stress, gut barrier damage, and microbiota dysbiosis in juvenile genetica... by Qiang Hao, Rolf Erik Olsen, Einar Ringø, Qianwen Ding, Tsegay Teame, Yuanyuan Yao, Chao Ran, Yalin Yang, Zhen Zhang, Zhigang Zhou

“…On the contrary, feeding with 0.3T23 negatively affects the gut microbiota diversity and structure of tilapia. Therefore, a 0.2 g/kg dose is suggested to supplement the diet of Nile tilapia to improve liver health and modulate the gut microbiota profile of the fish positively. …”
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SIGNIFICANCE OF ETV6-RUNX1 FUSION GENE TRANSCRIPT DETECTION IN PEDIATRIC B-CELL PRECURSOR ACUTE LYMPHOBLASTIC LEUKEMIA WITH TRANSLOCATION t(12;21)(p13;q22) by G. A. Tsaur, Т. О. Riger, A. M. Popov, T. Yu. Verzhbitskaya, L. V. Vakhonina, A. A. Vlasova, Yu. V. Olshanskaya, А. N. Kazakova, O. V. Streneva, O. V. Makarova, S. V. Tsvirenko, L. I. Saveliev, О. R. Arakaev, L. G. Fechina

“…Translocation t(12;21)(p13;q22) is one of the most common structural genetic abnormalities in childhood acute lymphoblastic leukemia (ALL). …”
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Design, Fabrication, and Application of GaN-Based Micro-LED Arrays With Individual Addressing by N-Electrodes by Enyuan Xie, Mark Stonehouse, Ricardo Ferreira, Jonathan J. D. McKendry, Johannes Herrnsdorf, Xiangyu He, Sujan Rajbhandari, Hyunchae Chun, Aravind V. N. Jalajakumari, Oscar Almer, Grahame Faulkner, Ian M. Watson, Erdan Gu, Robert Henderson, Dominic O'Brien, Martin D. Dawson

“…Compared to conventional GaN-based LED arrays, this array design employs a reversed structure of common and individual electrodes, which makes it innovative and compatible with n-type metal-oxide-semiconductor (NMOS) transistor-based drivers for faster modulation. …”
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Genetic influence of the brain imaging phenotypes, brain and cerebrospinal fluid metabolites and brain genes on migraine subtypes: a Mendelian randomization and multi-omics study by Ping-An Zhang, Jie-Lin Wang, Mei-Hua Dong, Xiang-Chun Huang, Nai-Jian Li, Run-Dong Qin, Jing Li

“…Additionally, We also applied summary-data-based MR (SMR) to detect brain-region-specific genes with potential causal effects. …”
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Association of critically short telomeres with brain and blood markers of ageing and Alzheimer’s disease in older adults by Asrar Lehodey, Perla Kaliman, Cassandre Palix, Robin de Florès, Edelweiss Touron, Anne-Laure Turpin, Séverine Fauvel, Florence Mézenge, Brigitte Landeau, Anne Chocat, Agathe Vrillon, Claire Paquet, Denis Vivien, Vincent de La Sayette, Gaël Chételat, Géraldine Poisnel, the Medit-Ageing Research Group

“…Using linear regressions, we analyzed the relationship between an innovative marker of telomere shortening, the percentage of CST (%CST), structural, functional and molecular neuroimaging outcomes, and multiple blood-based biomarkers related to AD pathophysiology. …”
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Survey of gut microbial biogeography and their functional niche in the grow-finishing swine of ordinary feeding by Lili Cao, Lili Cao, Wei Guo, Shiyu Yang, Shiyu Yang, Anum Ali Ahmad, Yuntao Dong, Cen Gong, Shuoqi Wang, Xuemin Yang, Zhentao Cheng, Zhihong Yan, Zhihong Yan, Weiwei Wang

“…The findings provide essential data for assessing the role of the intestinal microbiome in maintaining and enhancing swine health and productivity, offering fundamental guidance for further exploration of host-microbe interaction mechanisms and regulatory pathways.…”
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Genome-wide identification of VOZ gene family in ten cotton species and the function analysis of GhVOZ2 involved in heat stress response by Xiangxiang Hu, Kailu Chen, Shuangquan Xie, Quanliang Xie, Xifeng Chen, Zhuang Meng, Asigul Ismayil, Xiang Jin, Shandang Shi, Fei Wang, Hongbin Li

“…Chromosome location and collinearity analysis revealed that this gene family had experienced segment duplication events. The exon-intron structure and conserved motif analysis showed high conservations in each branch of the cotton VOZ genes. …”
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