Effect of soy isoflavones on intraepithelial lymphocytes, goblet cells and long leptin receptor in intestinal of rats by TANG Xiuying, CHEN Zhengli, LUO Qihui, ZHANG Xiaolong

“…The metabolites of soy isoflavones showed structural and functional similarities to estradiol. …”
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Association between post-PCI vessel fractional flow reserve (vFFR) and optical coherence tomography (OCT) findings: Results from the FAST OCT study by Annemieke C. Ziedses des Plantes, Alessandra Scoccia, Frederik T.W. Groenland, Maria N. Tovar Forero, Mariusz Tomaniak, Janusz Kochman, Wojciech Wojakowski, Pawel Gąsior, Koen Ameloot, Tom Adriaenssens, Wijnand K. den Dekker, Rutger-Jan Nuis, Isabella Kardys, Nicolas M. Van Mieghem, Ernest Spitzer, Joost Daemen

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Temporal evolution and factors influencing visual function and RNFL thickness in ethambutol-associated optic neuropathy by Taimin Guo, Yue Fu, Xiaoyu Xu, Xiaoning Liu, Yurong Zhang, Hui Yang

“…Abstract Purpose This study aimed to investigate the temporal evolution and influencing factors of visual function and optic nerve structure in ethambutol-associated optic neuropathy (EON). …”
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Curve Behavior of Distal Segments After Posterior‐Only Hemivertebra Resection for Congenital Cervicothoracic Scoliosis by Yang Li, Zezhang Zhu, Wanyou Liu, Saihu Mao, Zhen Liu, Xu Sun, Yong Qiu, Benlong Shi

“…However, the curve behavior of distal non‐structural compensatory curves and its possible mechanisms were unclear. …”
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Optimization of the Pedagogical Process in Teaching Chemistry to First-Year Students of the Ural State Medical University by E. Yu. Ermishina, N. A. Naronova, N. N. Kataeva, K. O. Golitsyna, N. A. Belokonova

“…Statistical processing of data on exam results and rating scores in the semester was carried out in the Microsoft Excel 2019 program. …”
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Mechanism and quantitative traceability of anomalous outflow of unloaded gas from protective layer mining under complex tectonics by Xuexi CHEN, Xingyu CHEN, Jiaying HU, Aitao ZHOU, Jian XIAO, Jihong SUN, Zhilong YAN

“…By coupling simulation analysis of FLAC3D-COMSOL under complex structural stress, the mechanical evolution law and stress relief and permeability enhancement mechanism of protective layer mining are studied. …”
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Increased vulnerability to psychological distress and suicidal ideation among transgender women with self-reported disabilities in San Francisco, California by Abtin Shafie, Alexis Salvatore, Riley Shea, Eileen Yu, Oyku Ozyucel, Ansharan Akbar, Bow Suprasert, Erin C. Wilson, Willi McFarland, Kelly D. Taylor, Sean Arayasirikul

“…OBJECTIVE: Research among transgender women has found health, but especially mental health, to be shaped by social inequities and multiple, intersectional, structural vulnerabilities. While some studies have shown that transgender adults are also more likely to have a disability than cisgender adults, few studies have explored this intersection. …”
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Clinical profiles and health-related quality of life changes after treatment in advanced colorectal cancer patients: a nationwide study in China by Hongwei Liu, Ziyao Jia, Huifang Xu, Xiaoyang Wang, Hong Wang, Ruihua Kang, Qiong Chen, Xiaoli Guo, Ranran Qie, Mengfei Zhao, Cheng Cheng, Liyang Zheng, Shuzheng Liu, Yin Liu, Shaokai Zhang, China Working Group on Colorectal Cancer Survey

“…The multivariable regressions and structural equation model (SEM) were used to assess the association between characteristics and HRQOL. …”
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Repositioning FDA-Approved Sulfonamide-Based Drugs as Potential Carbonic Anhydrase Inhibitors in <i>Trypanosoma cruzi</i>: Virtual Screening and In Vitro Studies by Eyra Ortiz-Pérez, Adriana Moreno-Rodríguez, Timoteo Delgado-Maldonado, Jessica L. Ortega-Balleza, Alonzo González-González, Alma D. Paz-González, Karina Vázquez, Guadalupe Avalos-Navarro, Simone Giovannuzzi, Claudiu T. Supuran, Gildardo Rivera

“…Future studies should focus on structural modifications to improve selectivity. Integrating docking, parasitological, and enzymatic data is crucial for optimizing drug candidates for Chagas disease.…”
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Health poverty reduction effect of medical insurance in China’s middle-aged and elderly populations: a cross-sectional study by Haijun Yang, Rui Chen, Ye Li, Qunhong Wu, Linghan Shan, Bing Wu, Fang Yin, Yiyun Zhang, Yongqiang Lai, Xinwei Liu, Wanxin Tian, Xiyu Zhang, Yujuan Xu, Wenqing Miao, Baoguo Shi, Feifei Leng

“…Objectives In the context of demographic structure and disease spectrum changes: to study the role of the medical insurance system in providing protection and risk resilience for middle-aged and elderly vulnerable groups who are prone to impoverishment by medical expenses (IME), identify the vulnerable points and propose recommendations for improving the medical insurance system.Setting The research used data from the 2018 China Health and Retirement Longitudinal Study.Participants 9184 households were included in the research ultimately.Primary and secondary outcome measures We use the WHO’s recommended composite measure of disease-related poverty and algorithm to determine the occurrence of IME in households. …”
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Seeking Correlation Among Porin Permeabilities and Minimum Inhibitory Concentrations Through Machine Learning: A Promising Route to the Essential Molecular Descriptors by Sara Boi, Silvia Puxeddu, Ilenia Delogu, Domenica Farci, Dario Piano, Aldo Manzin, Matteo Ceccarelli, Fabrizio Angius, Mariano Andrea Scorciapino, Stefan Milenkovic

“…The automated protocol presented here could be used to inspect, in silico, many alternatives of a given molecular structure, with the output being the list of the best candidates to be then synthesized and tested. …”
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Predicting leakage of the VERCORS mock-up and concrete containment buildings - a digital twin approach by Laurent Charpin, Jessica Haelewyn, Anass Cherki El Idrissi, Julien Niepceron, Benoît Masson, Charles Toulemonde, Guillaume Boulant, Jean-Philippe Mathieu, François Hamon, Sylvie Michel-Ponnelle, Jean-Marie Hénault, Frédéric Taillade, Jean-Luc Adia, Florian Escoffier

“…An important numerical effort has also been made to implement structural computations of the mock-up and to capitalize these computations as well as their post-processing (so as to compare automatically with the monitoring data) in what can be called a digital twin of the mock-up. …”
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Interface characterization of Cu18150/Al1060/Cu18150 laminated composite produced by combined cast-roll and hot-roll technique by Mahmoud Ebrahimi, Yuchao Zhao, Huisheng Cai, Shokouh Attarilar, Zhengping Shang, Qudong Wang

“…Scanning electron microscopy (SEM) and energy-dispersive spectroscopy (EDS) analyses elucidate the formation of IMCs at the interfaces, with predicted formation sequences influenced by Gibbs free energy data. Electron backscatter diffraction (EBSD) analysis indicates that hot rolling promotes grain refinement in Cu18150, resulting in a homogeneous structure with elongated fine grains, while Al1060 shows nonuniform grain distribution. …”
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Identification and Analysis of <i>KAS II</i>, <i>FAT</i>, <i>SAD</i>, and <i>FAD</i> Gene Families in <i>Hippophae rhamnoides</i> by Alexander A. Arkhipov, Ekaterina M. Dvorianinova, Anastasia A. Turba, Roman O. Novakovskiy, Yury A. Zubarev, Pavel A. Predushchenko, Elizaveta A. Sigova, Daiana A. Zhernova, Elena V. Borkhert, Elena N. Pushkova, Chengjiang Ruan, Nataliya V. Melnikova, Alexey A. Dmitriev

“…As a result of structure and phylogenetic analyses, 4 <i>KAS II</i>, 8 <i>FAT</i>, 9 <i>SAD</i>, and 12 <i>FAD</i> genes were identified in the <i>H. rhamnoides</i> genome, which were classified into subfamilies: <i>KAS II, FATA</i>, <i>FATB</i>, <i>FAD2</i>, <i>FAD3</i>, <i>FAD6</i>, and <i>FAD7/8</i>. …”
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Differential effects of oral versus intravenous hydrocortisone and dexamethasone on capillary blood glucose levels in adult inpatients − a single centre study by Vaishali Limbachia, Ian Nunney, Daniel J. Page, Hannah A. Barton, Leena K. Patel, Georgia N. Thomason, Stephan L. Green, Kieran F.J. Lewis, Ketan Dhatariya

“…An auto-regressive covariance structure was employed to model correlations between repeated measurements. …”
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Whole-Genome Resequencing to Identify Selection Signatures Associated with High Fertility in Lüliang Black Goat by Xu Wang, Zhenqi Zhou, Xinrui Chai, Jie Li, Wannian Wang, Zhixu Pang, Lifen Cheng, Caihong Cheng, Liying Qiao, Yangyang Pan, Kaijie Yang, Wenzhong Liu, Jianhua Liu

“…Based on whole-genome resequencing data, this study comprehensively assessed the population structure and genetic diversity of LBG and explored the related genes that affect reproductive performance. …”
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Technical note: Flow cytometry assays for the detection, counting and cell sorting of polyphosphate-accumulating bacteria by C. Bouquet, H. Billard, H. Billard, C. C. Bidaud, J. Colombet, J. Colombet, Y.-T. Chang, J. Artigas, I. Batisson, K. Benzerara, F. Skouri-Panet, E. Duprat, A.-C. Lehours

“…This requires high-throughput methods to characterize their structure and dynamics in ecosystems. A promising strategy is to combine the staining of intracellular polyphosphate granules and their subsequent detection by flow cytometry, enabling rapid data acquisition. …”
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Erythritol as a Next-Generation Sweetener: properties, metabolism, cardiovascular risk and gut health implications – A literature review by Julia Skowrońska-Borsuk, Martyna Narożniak, Adrianna Ewa Pękacka, Bartłomiej Czerwiec, Adam Borsuk, Joanna Katarzyna Pergoł, Malwina Wojtas, Julia Borkowska, Zuzanna Krupa, Julia Sposób

“…However, these findings are inconclusive and require further investigation. Emerging animal data indicate erythritol may modulate gut epithelial structure via microbiota-derived metabolites. …”
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Anti-Migratory Activity of Brazilin Chemodiversification on Breast Cancer Cells by Alberto Hernández-Moreno, Dania A. Nava-Tapia, Miriam D. Zuñiga-Eulogio, Jorge Bello-Martínez, Monserrat Olea-Flores, Tadeo Hernández-Moreno, Mario Ordoñez, Ana E. Zacapala-Gómez, Miguel A. Mendoza-Catalán, Napoleón Navarro-Tito

“…In this study, we isolated brazilin from the heartwood of <i>Haematoxylum brasiletto</i>; then, we performed a semi-synthesis by adding three methyl or acetyl groups to the core structure of brazilin. We confirmed the identity of brazilin and its derivatives by spectroscopic data (¹H NMR and ¹³C NMR) and measured their purity by optical rotation. …”
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An effective fluorescence strategy based on xanthine oxidase catalysis and the carbon dots’ specific response to ·OH for aminophylline pharmacokinetic studies by Chenfang Miao, Menghan Zhang, Ying Zheng, Xiaoyan Lin, Shuangying Yang, Linlin Xu, Sitong Lu, Zhengjun Huang, Jianyong Huang, Yanjie Zheng, Shaohuang Weng

“…In this study, high quantum yield carbon dots (CA/EDA-CDs) were synthesized via a hydrothermal method using riboflavin as the carbon source, citric acid and ethylenediamine as functionalizing agents and dopants. The luminescent structure of CA/EDA-CDs, featuring a π-conjugated system (aromatic C=C and graphite N) and surface chromophores (C=N/C=O) connected via C-N, C-O, and hydrogen bonds, was controllably modulated by hydroxyl radical (·OH). …”
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