Advances in diffuse glial tumors diagnosis by Luis Filipe de Souza Godoy, Vitor Ribeiro Paes, Aline Sgnolf Ayres, Gabriela Alencar Bandeira, Raquel Andrade Moreno, Fabiana de Campos Cordeiro Hirata, Frederico Adolfo Benevides Silva, Felipe Nascimento, Guilherme de Carvalho Campos Neto, Andre Felix Gentil, Leandro Tavares Lucato, Edson Amaro Junior, Robert J. Young, Suzana Maria Fleury Malheiros

“…This article will explore morphologic pathology and molecular/genetics techniques (immunohistochemistry, genetic sequencing, and methylation profiling), which are pivotal in diagnosis, besides the correlation of structural neuroimaging radiophenotypes to pathology and genetics. …”
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Rapid On-Site Histopathological Analysis of Kidney Biopsy With Dynamic Full-Field Optical Coherence Tomography by Léa Zuccarelli, Quentin Bernard, Georges Tarris, Laurent Martin, Mathilde Funes de la Vega, Amélie Jacq, Jean-Michel Rebibou, Claire Tinel, Claude Boccara, Olivier Thouvenin, Jean-Marie Chassot, Marion Rabant, Julien Zuber, Christophe Legendre, Jean-Pierre Quenot, Marie-Noëlle Peraldi, Lucile Amrouche, Anne Scemla, Nathalie Chavarot, Dany Anglicheau, Mathieu Legendre, Thomas Maldiney

“…The clinical and biological data were prospectively collected. Histopathological analysis of kidney biopsies was conducted using both conventional stains and dynamic D-FF-OCT imaging. …”
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Distinct subnetworks of the mouse anterior thalamic nuclei by Houri Hintiryan, Mitchell Rudd, Sumit Nanda, Adriana E. Gutierrez, Darrick Lo, Tyler Boesen, Luis Garcia, Jiandong Sun, Christian Estrada, Hyun-Seung Mun, Seita Yamashita, Yeji E. Han, Ian Bowman, Lin Gou, Chunru Cao, Jennifer Gonzalez, Keivan Moradi, Qiuying Zhao, Inga Yenokian, Aishwarya Dev, Brian Zingg, Hanpeng Xu, Qing Xue, Muye Zhu, Lijuan Liu, Xin Chen, Zhixi Yun, Hanchuan Peng, Nicholas N. Foster, Hong-Wei Dong

“…Therefore, the ATN provide a promising avenue to investigate the relationship between structural and functional complexity with neuron type diversity. …”
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EP240801a/XRF 240801B: An X-Ray Flash Detected by the Einstein Probe and the Implications of Its Multiband Afterglow by Shuai-Qing Jiang, Dong Xu, Agnes P. C. van Hoof, Wei-Hua Lei, Yuan Liu, Hao Zhou, Yong Chen, Shao-Yu Fu, Jun Yang, Xing Liu, Zi-Pei Zhu, Alexei V. Filippenko, Peter G. Jonker, A. S. Pozanenko, He Gao, Xue-Feng Wu, Bing Zhang, Gavin P Lamb, Massimiliano De Pasquale, Shiho Kobayashi, Franz Erik Bauer, Hui Sun, Giovanna Pugliese, Jie An, Valerio D’Elia, Johan P. U. Fynbo, WeiKang Zheng, Alberto J. Castro-Tirado, Yi-Han Iris Yin, Yuan-Chuan Zou, Adam T. Deller, N. S. Pankov, A. A. Volnova, A. S. Moskvitin, O. I. Spiridonova, D. V. Oparin, V. Rumyantsev, O. A. Burkhonov, Sh. A. Egamberdiyev, V. Kim, M. Krugov, A. M. Tatarnikov, R. Inasaridze, Andrew J. Levan, Daniele Bjørn Malesani, Maria E. Ravasio, Jonathan Quirola-Vásquez, Joyce N. D. van Dalen, Javi Sánchez-Sierras, Daniel Mata Sánchez, Stuart P. Littlefair, Jennifer A. Chacón, Manuel A. P. Torres, Ashley A. Chrimes, Nikhil Sarin, Antonio Martin-Carrillo, Vik Dhillon, Yi Yang, Thomas G. Brink, Rebecca L. Davies, Sheng Yang, Amar Aryan, Ting-Wan Chen, Albert K. H. Kong, Wen-Xiong Li, Rui-Zhi Li, Jirong Mao, Ignacio Pérez-García, Emilio J. Fernández-García, Moira Andrews, Joseph Farah, Zhou Fan, Estefania Padilla Gonzalez, D. Andrew Howell, Dieter Hartmann, Jing-Wei Hu, Páll Jakobsson, Cheng-Kui Li, Zhi-Xing Ling, Curtis McCully, Megan Newsome, Benjamin Schneider, Kaew Samaporn Tinyanont, Ning-Chen Sun, Giacomo Terreran, Qing-Wen Tang, Wen-Xin Wang, Jing-Jing Xu, Wei-Min Yuan, Bin-Bin Zhang, Hai-Sheng Zhao, Juan Zhang

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The haplotype-resolved telomere-to-telomere genome and OMICS analyses reveal genetic responses to tapping in rubber tree by Chaochao Li, Yuan Yuan, Zhiyi Nie, Tingkai Wu, Zhiyuan Wang, Jiangxia Qiao, Zhi Deng, Xiaobo Wang, Dong Xu, Xu Wang, Shuo Cao, Bingqin Li, Zewei An, Wenguan Wu, Zhongxin Jin, Huasun Huang, Wei Hu, Yongfeng Zhou, Han Cheng

“…We present the haplotype-resolved, telomere-to-telomere, gap-free genome assembly of the cultivar CATAS 7-33–97, with both haplotypes containing complete telomeric and centromeric regions. Structural variations, including a 32.71 Mb inversion on chromosome 8, are identified. …”
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Efficacy and safety of cannabidiol in a single-center pediatric drug-resistant epilepsy cohort: a retrospective study by Ambra Butera, Ambra Butera, Giulia Spoto, Graziana Ceraolo, Maria Grella, Ivana Giunta, Maria Ludovica Albertini, Carla Consoli, Caterina Sferro, Maria Spanò, Gabriella Di Rosa, Antonio Gennaro Nicotera

“…Clinical, demographic, and instrumental data were retrospectively extracted from the medical records and caregivers’ reports. …”
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Phenotypically distinguishable eosinophilic cells do not impact epithelial functions in a triple-culture in vitro intestinal model by Christoph Benkstein, Laurin Mosig, Daniel Vondran, Heidi Schlichting, Lea Kissing, Bente Wohlert, Ida Gensmer, Larissa Nogueira de Almeida, Peter König, Peter König, Kerstin Fibelkorn, Anna Kordowski, Stefanie Derer-Petersen, Christian Sina, Christian Sina, Yves Laumonnier, Yves Laumonnier

“…In-depth characterization by real-time PCR, flow cytometry, functional assay and electron microscopy showed that only butyrate and dibutyryl-cAMP generated phenotypically distinct eosinophilic cells with different activation statuses, marked by differential expression of surface markers CD11c and CD62L, increased expression of eosinophil specific genes, and development of eosinophilic structural features. Then, a triple-culture system encompassing the enterocytic cell line Caco-2 and the secretory cell line HT29-MTX complemented with eosinophilic differentiated cells was established. …”
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Feasibility study of single-image super-resolution scanning system based on deep learning for pathological diagnosis of oral epithelial dysplasia by Zhaochen Liu, Zhaochen Liu, Peiyan Wang, Peiyan Wang, Nian Deng, Hui Zhang, Hui Zhang, Fangjie Xin, Xiaofei Yu, Xiaofei Yu, Mujie Yuan, Mujie Yuan, Qiyue Yu, Yuhao Tang, Keke Dou, Jie Zhao, Bing He, Jing Deng, Jing Deng

“…Both the DS30R and Nikon scanners demonstrate high sensitivity and specificity for detecting structural features in OED pathological images; however, DS30R excels at identifying certain cellular features. …”
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Quality of Surface and Groundwater in the Sierra de Amula Region, Jalisco, Mexico by Oscar Raúl Mancilla-Villa, Fabiola Villafaña-Castillo, Álvaro Can-Chulim, Rubén Darío Guevara-Gutiérrez, José Luis Olguín-López, Elia Cruz-Crespo, Jonas Alan Luna-Fletes, Juan Uriel Avelar-Roblero

“…Each sample was evaluated for its pH, electrical conductivity, and ionic concentration (Ca²⁺, Mg²⁺, Na⁺, K⁺, CO₃²⁻, HCO₃⁻, CI⁻, SO₄²⁻). For data analysis, we determined the ionic concentrations and the salinity and sodicity indexes, including the electrical conductivity, pH, sodium adsorption ratio (SAR), and cationic ratio of soil structural stability (CROSS). …”
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Lessons from the PROTECT-CH COVID-19 platform trial in care homes by Philip M Bath, Jonathan Ball, Matthew Boyd, Heather Gage, Matthew Glover, Maureen Godfrey, Bruce Guthrie, Jonathan Hewitt, Robert Howard, Thomas Jaki, Edmund Juszczak, Daniel Lasserson, Paul Leighton, Val Leyland, Wei Shen Lim, Pip Logan, Garry Meakin, Alan Montgomery, Reuben Ogollah, Peter Passmore, Philip Quinlan, Caroline Rick, Simon Royal, Susan D Shenkin, Clare Upton, Adam L Gordon

“…Generic challenges included working across the four home nations with their different structures and regulations. Limitations The feasibility of contracting between the sponsor and the principal investigators, general practitioners and care homes; screening, consent and treatment of care home residents; data acquisition and the potential benefit of postexposure prophylaxis were never tested. …”
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Investigating the Mediating Role of Self-Efficacy in the Relationship between Job Demand and Role Ambiguity with Employee Well-Being by Mahnaz Rahimi, Mohammad Hassani, Hasen Ghalavand

“…</p> <p style="text-align: left;"><strong>3.Methodology</strong></p> <p style="text-align: left;">In this article, we intended to model the factors affecting employees' well-being with the mediation of self-efficacy using a quantitative approach and structural equation modeling. For this purpose, we first determined the independent, dependent and mediating variables based on the backgrounds. …”
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Genome-Wide Identification and Evolutionary Analysis of <i>Ionotropic Receptors</i> Gene Family: Insights into Olfaction Ability Evolution and Antennal Expression Patterns in <i>Or... by Wen-Qi Yang, Ge Ding, Lin-Lin Wang, Chi-Jie Yin, Hai-Yue Wu, Hua-Bin Zhang, Qiu-Ning Liu, Sen-Hao Jiang, Bo-Ping Tang, Gang Wang, Dai-Zhen Zhang

“…Based on the whole-genome data of <i>O. oratoria</i>, we identified and analyzed 50 members of the <i>IR</i> gene family (<i>OratIRs</i>) through bioinformatics approaches. …”
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PUI Heating in the Supersonic Solar Wind by Parisa Mostafavi, Laxman Adhikari, Bishwas L. Shrestha, Gary P. Zank, Merav Opher, Matthew E. Hill, Heather A. Elliott, Pontus C. Brandt, Ralph L. McNutt, David J. McComas, Andrew R. Poppe, Elena Provornikova, Romina Nikoukar, Peter Kollmann, S. Alan Stern, Kelsi N. Singer, Anne Verbiscer, Joel Parker

“…Using a PUI-mediated plasma model, we explore shock structures and PUI heating, finding that shocks preferentially heat PUIs over the thermal solar wind in the outer heliosphere. …”
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Integrated land systems for sustainable food production and biodiversity conservation in the semi-arid to moist tropics: stakeholder perspectives from Andhra Pradesh, India by Iris Berger, Iris Berger, Manan Bhan, Rekha Bhangaonkar, Abhishek Chaudhary, Gopinath R. Mallapu, Tanaya Nair, Eswarayya Ramireddy, Rengalakshmi Raj, Vijay Ramprasad, Vishnupriya Sankararaman, Vartika Singh, A. S. Hareesha, Parthiba Basu, Boraiah Bheemappa, Chandrashekhar Biradar, Archana Chatterjee, Ramdas Dagam, Israel Oliver King Edwin Devarathna, Reuben Gergan, Vinuthna Patibandla, Benjamin Paul, Vamshi Krishna Pulluri, Nandini Rajamani, Mounika Ramireddy, Imran Siddiqui, Sowmithri Vadaganambi Ramachari, Farida Tampal, Swati Udayraj, Tata Venkateswarlu, Tata Venkateswarlu, Lynn V. Dicks, Lynn V. Dicks

“…To achieve a vision of an equitable and sustainable food system and of multifunctional and nature-positive land systems, we advocate for an end to harmful subsidies, improvements in infrastructures and social organisations, dietary shifts, and creation of both supporting financial structures and sustainable and transparent value chains. …”
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Metabolic Acidosis Is Associated With an Accelerated Decline of Allograft Function in Pediatric Kidney Transplantation by Agnieszka Prytula, Rukshana Shroff, Ineke van Gremberghe, Kai Krupka, Justine Bacchetta, Elisa Benetti, Ryszard Grenda, Isabella Guzzo, Nele Kanzelmeyer, Bahar Büyükkaragöz, Birgitta Kranz, Hülya Nalçacıoğlu, Jun Oh, Lars Pape, Mohan Shenoy, Anne-Laure Sellier-Leclerc, Burkhard Tönshoff, Gema Ariceta, Atif Awan, Sevcan Bakkaloğlu, Marjolein Bonthuis, Charlotte Bootsma Robroeks, Antonia Bouts, Martin Christian, Marlies Cornelissen, Ali Duzova, Nasrin Esfandiar, Luciana Ghio, Ryszard Grenda, Isabella Guzzo, Maria Herrero Goni, Julien Hogan, Nattaphorn Hongsawong, Nele Kanzelmeyer, Aysun Karabay Bayazit, Gülşah Kaya Aksoy, Noel Knops, Linda Koster Kamphuis, Daniella Levy Erez, Victor Lopez-Baez, Alvaro Madrid, Stephen Marks, Anette Melk, Luisa Murer, Lars Pape, Licia Peruzzi, Edita Petrosyan, Evgenia Preka, Nikoleta Printza, Andreea Liana Rachisan, Ann Raes, Mohan Shenoy, Oguz Soylemezoglu, Luca Dello Strologo, Ana Teixeira, Rezan Topaloglu, Markus Weitz, Jakub Zieg, Galia Zlatanova, Christian Patry, Jerome Harambat, Ayşe Ağbaş, Varvara Askiti, Marina Avramescu, Justine Bacchetta, Sevcan Bakkaloglu, Marjolein Bontuis, Caroline Booth, Laurene Dehoux, Giacomo Dizazzo, Dorota Drozdz, Ismail Dursun, Michaela Gessner, Jaap Groothoff, Giuliana Guido, Isabella Guzzo, Aysun Karabay Bayazit, Guenter Klaus, Linda Koster-Kamphuis, Alexander Lalayiannis, Maren Leifheit-Nestler, Sinha Manish, Chiara Matteucci, Jun Oh, Ozan Ozkaya, Edita Petrosyan, Christine Pietrement, Agnieszka Prytula, George Reusz, Franz Schaefer, Claus Peter Schmitt, Anne Schön, Fatma Lale Sever, Stella Stabouli, Serra Sürmeli Döven, Camilla Tondel, Enrico Verrina, Enrico Vidal, Dean Wallace, Zainab Arslan, M. Bald, H. Fehrenbach, D. Haffner, M. Hansen, C. Hempel, U. John, G. Klaus, J. König, B. Lange-Sperandio, D. Müller, J. Oh, L. Pape, M. Pohl, K. Sauerstein, G. Schalk, H. Staude, P. Strotmann, L.T. Weber, M. Weitz, L. Berta, K. Heindl-Rusai

“…Methods: This registry study collected data up to 10 years posttransplant. Survival analysis for a composite end point of graft loss or estimated glomerular filtration rate (eGFR) ≤ 30 ml/min per 1.73 m2 or ≥50% decline from eGFR at month 3 posttransplant was performed. …”
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Epithelial-to-mesenchymal transition is an active process in the large airways of patients with asthma-COPD overlap and partially abrogated by inhaled corticosteroid treatment: a b... by Surajit Dey, Wenying Lu, Prabuddha S. Pathinayake, Maddison Waters, Greg Haug, Josie Larby, Heinrich C. Weber, Peter A. B. Wark, Peter A. B. Wark, Mathew Suji Eapen, Sukhwinder Singh Sohal

“…Additionally, the degree of RBM fragmentation was evaluated, a key tissue structural marker of EMT.ResultsCompared to healthy controls and asthmatics, ACO had the greatest fragmentation of RBM (P &lt; 0.01). …”
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Microstructural integrity of autonomic central nervous tracts is linked to cardiovascular health by Janis M. Nolde, Alexander Rau, Elias Kellner, Horst Urbach, Cornelius Weiller, Fabian Bamberg, Jakob Weiss, Marco Reisert, Jonas A. Hosp

“…Differential patterns were observed in cortical versus subcortical CAN structures, suggesting distinct pathophysiological roles within the heart-brain axis.…”
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Geological characteristics of biogenic gas formation and direction of favorable zones in the Quaternary mudstone of the Qaidam Basin, China by Jixian Tian, Zeyu Shao, Jian Li, Dekang Song, Zhou Fei, Ya'nan Li, Wei Sha, Hao Zhang, Lili Hou, Xiaoqiu Zhang, Haining Zhang, Yixuan Yang

“…In this study, we utilize core data from the mudstone sections of two newly drilled wells in the study area as the object, and carry out a comprehensive study of the formation and reservoir characteristics of mudstone biogas through systematic experimental analysis, on the basis of which, favourable exploration areas for mudstone biogas are identified. …”
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Co-circulation and genetic characterization of genotype I and II feline bocavirus strains in domestic cats from Northern Vietnam by Hieu Van Dong, Giang Thi Huong Tran, Yen Hoang Thi Nguyen, Thiet Chi Ngo, Amonpun Rattanasrisomporn, Chaiwat Boonkaewwan, Dao Anh Tran Bui, Jatuporn Rattanasrisomporn

“…DNA was extracted and screened for FBoV using conventional polymerase chain reaction targeting the non-structural (NS)-1 gene. Positive samples were subjected to Sanger sequencing, and partial NS1 sequences were analyzed using MEGA X for phylogenetic inference. …”
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Cultural and behavioral drivers of zoonotic disease transmission and persistence among diverse pastoralist communities in East Africa by Dismas C.O. Oketch, Ruth Njoroge, Tonny O. Ngage, Asha Abdikadir Omar, Abdulai Magarre, Raphael Pasha, John Gachohi, Samuel Waiguru Muriuki, Samoel Ashimosi Khamadi, Ali Duba Boru, Boku Bodha, Lydia Kilowua, Nazaria Wanja Nyaga, Humphrey Kariuki Njaanake, Eunice Kamaara, Walter Jaoko, M. Kariuki Njenga, Eric Osoro, Dalmas Omia

“…Methods This study adopts a One Health approach, employing a range of participatory methods including informal observations, “go-along interviews,” narrative-, and key informant- interviews, to explore the cultural, behavioral, and structural drivers of zoonotic disease transmission among pastoralist communities in East Africa. …”
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