Confirmatory study on the retention rate of ketogenic diet therapy and related factors in children with drug‐resistant epilepsy: A single‐center cohort study by Jie Zhang, Qiang Gu, Yuan Wu, Han Xie, Cuijie Wei, Yao Zhang, Taoyun Ji, Xinhua Bao, Xingzhi Chang, Yuehua Zhang, Yuwu Jiang, Ye Wu

“…Methods This was a single‐center cohort study. Baseline data were collected, and regular follow‐up was conducted after KDT treatment. …”
Get full text

Characterization of the 1966 Camp Century subglacial core: a multiscale analysis by C. M. Collins, N. Perdrial, N. Perdrial, P.-H. Blard, P.-H. Blard, N. Keulen, W. C. Mahaney, H. Mastro, J. Souza, D. M. Rizzo, Y. Marrocchi, P. C. Knutz, P. R. Bierman

“…Microscale grain size and shape analysis, conducted using scanning electron microscopy, showed an abundance of fine-grained materials in the lower part of the core and no correspondence between grain shape parameters and sedimentary structures. These multiscale data define five distinct stratigraphic units within the core based on sedimentary process; <span class="inline-formula"><i>k</i></span>-means clustering analysis supports this unit delineation. …”
Get full text

Age features of myocardial remodeling in men with ischemic chronic heart failure and renal dysfunction by D. A. Lashkul

“…However, in most studies structural remodeling of the myocardium was analyzed without sex and age characteristics. …”
Get full text

Multi-field information fusion-based analysis of the macroscopic and mesoscopic damage evolution and location identification of caving and water-conducting fracture zones for minin... by Jiangbo WEI, Shuangming WANG, Lang LIU, Baoning WEI, Deyu CHONG, Zhizhen LIU, Dongkui LI, Dengdeng ZHUANG, Jing ZHOU

“…ObjectiveFor the coal mining areas in the middle reaches of the Yellow River, there is an urgent need to determine the failure characteristics of the mining overburden and the spatial structural evolution of caving and water-conducting fracture zones in the overburden, which is recognized as the major challenge in coal mining through gangue grouting filling in goaves. …”
Get full text

CLINICAL PROFILE OF PATIENTS WITH EARLY AXIAL SPONDYLOARTHRITIS (RUSSIAN COHORT OF PATIENTS) by E. E. Gubar', A. G. Bochkova, T. V. Dubinina, A. B. Dyomina, O. A. Rumyantseva, M. M. Urumova, S. V. Shubin, A. A. Godzenko, A. V. Smirnov, E. Yu. Tyukhova, S. I. Glukhova, Sh. F. Erdes

“…X-ray revealed definite SI in 49.3% of patients («classic» AS). According to MRI data, 30.1% of patients with active SI and without structural changes of sacroiliac joints had pre-radiological stage of AS (by Russian version of modified New York criteria). 74.0% of patients fulfilled both sets of ASAS criteria for axSpA, 5.5% – met only I criteria set, whereas 20.5% – only II criteria set. …”
Get full text

Las brechas laborales que afectan a las mujeres desde la perspectiva de las ciencias económicas: un análisis de la producción científica en la base de datos Scopus - Labor market g... by Emanuel José Maldonado, Denis González-Argote, Rolando Eslava-Zapata, Alfredo Javier Pérez-Gamboa

“…This is particularly relevant in Latin American contexts, where unique economic and social structures pose specific challenges.…”
Get full text

The meaning of ‘quality’ of homecare for older people: a scoping review by Alex Hall, Vanessa Davey, Lisa McGarrigle, Jayne Astbury, Kimberly Lazo Green, Nisar Ahmed, Oleta Williams, Fiona Beyer, Barbara Hanratty, Debora Price

“…We identified four dimensions: (1) relationships and continuity of care; (2) bespoke care; (3) organisational and structural aspects of care; and (4) understanding of quality as a measurable construct. …”
Get full text

NDVI Estimation Throughout the Whole Growth Period of Multi-Crops Using RGB Images and Deep Learning by Jianliang Wang, Chen Chen, Jiacheng Wang, Zhaosheng Yao, Ying Wang, Yuanyuan Zhao, Yi Sun, Fei Wu, Dongwei Han, Guanshuo Yang, Xinyu Liu, Chengming Sun, Tao Liu

“…This study utilizes field data from five major crops (cotton, rice, maize, rape, and wheat) throughout their whole growth periods. …”
Get full text

Machine learning enhanced metal 3D printing: high throughput optimization and material transfer extensibility by Yuanjie Zhang, Cheng Lin, Yuan Tian, Jianbao Gao, Bo Song, Hao Zhang, Min Wang, Kechen Song, Binghui Deng, Dezhen Xue, Yonggang Yao, Yusheng Shi, Kun Kelvin Fu

“…The high throughput methodologies are mostly on obtaining the printed samples and their structural and physical properties, while ML is used for data analysis by model building for prediction (optimization), and understanding. …”
Get full text

MAPT-A152T mutation drives neuronal hyperactivity through Fyn-NMDAR signaling in human iPSC-Derived neurons: Insights into Alzheimer's pathogenesis by Maika Itsuno, Hirokazu Tanabe, Etsuko Sano, Takashi Sasaki, Chisato Oyama, Hiroko Bannai, Koichi Saito, Kazuhiko Nakata, Setsu Endoh-Yamagami, Hideyuki Okano, Sumihiro Maeda

“…In addition, transcriptomic analysis revealed structural changes specific to excitatory neurons with the A152T mutation. …”
Get full text

Serum and tear autoantibodies from NOD and NOR mice as potential diagnostic indicators of local and systemic inflammation in Sjögren’s disease by Shruti Singh Kakan, Sara Abdelhamid, Sara Abdelhamid, Yaping Ju, Yaping Ju, J. Andrew MacKay, J. Andrew MacKay, J. Andrew MacKay, Maria C. Edman, Indu Raman, Chengsong Zhu, Prithvi Raj, Sarah F. Hamm-Alvarez, Sarah F. Hamm-Alvarez

“…The LG produces the protein-rich aqueous component of tears, and SjD-associated autoimmune dacryoadenitis (AD) may thus alter tear autoantibody composition.MethodsThe presence of tertiary lymphoid structures (TLS) in LG from two murine models of SjD-associated AD, male non-obese diabetic (NOD) and male non-obese insulitis resistant (NOR) mice, were evaluated using immunofluorescence. …”
Get full text

Genetically predicted white matter microstructure mediates the relationship between risk factors and lacunar stroke by Qing Ye, Jie Zhang, Li Zhang, Benyan Luo, Xiangming Ye, Min Wu, Wenshi Wang, Yue Zou, Douglas Neville, Kaisi Ren, Shuchang Zhong, Haiying Xiang

“…MD and ISOVF in the ALIC may serve as structural brain reserves and early biomarkers of hypertension-induced pathophysiology associated with lacunar stroke.…”
Get full text

Comparative Analysis of Plasma Protein Dynamics in Women with ST-Elevation Myocardial Infarction and Takotsubo Syndrome by Shafaat Hussain, Sandeep Jha, Evelin Berger, Linnea Molander, Valentyna Sevastianova, Zahra Sheybani, Aaron Shekka Espinosa, Ahmed Elmahdy, Amin Al-Awar, Yalda Kakaei, Mana Kalani, Ermir Zulfaj, Amirali Nejat, Abhishek Jha, Tetiana Pylova, Maryna Krasnikova, Erik Axel Andersson, Elmir Omerovic, Björn Redfors

“…Differential expression and functional significance were assessed. Data are accessible on ProteomeXchange, ID PXD051367. …”
Get full text

Assessing the context within academic health institutions toward improving equity-based, community and patient-engaged research by Prajakta Adsul, Shannon Sanchez-Youngman, Elizabeth Dickson, Belkis Jacquez, Alena Kuhlemeier, Michael Muhammad, Katherine J. Briant, Bridgette Hempstead, Jason A. Mendoza, Lisa G. Rosas, Anisha Patel, Patricia Rodriguez Espinosa, Tabia Akintobi, Paige Castro-Reyes, Lori Carter-Edwards, Nina Wallerstein

“…Third, institutional structures created power imbalances and community mistrust which were identified as key barriers to P/CenR. …”
Get full text

Cognitive gains and cortical thickness changes after 12 weeks of resistance training in older adults with low and high risk of mild cognitive impairment: Findings from a randomized... by Simona Kušleikienė, Gal Ziv, Wouter A.J. Vints, Erika Krasinskė, Milda Šarkinaite, Orgesa Qipo, Ivan Bautmans, Uwe Himmelreich, Nerijus Masiulis, Vida J. Česnaitienė, Oron Levin

“…Background: In this randomized controlled trial, we assessed the neuroprotective effect of a 12-week resistance training (RT) program on executive control and cortical thickness of the prefrontal, temporal, parietal, and central cortex, regions prone to structural decline in individuals with mild cognitive impairment (MCI). …”
Get full text

Prospective Evaluation of a Novel Unidirectional Permanent Device for Intraoperative Brachytherapy by Abraham J. Wu, MD, Irini Youssef, MD, Gil’ad N. Cohen, MS, Paul B. Romesser, MD, Neil K. Taunk, MD, Karen Episcopia, MS, Christopher H. Crane, MD, Philip Paty, MD, Julio Garcia-Aguilar, MD, PhD, Martin Weiser, MD, J. Joshua Smith, MD, PhD, Garrett M. Nash, MD, Eugene Cha, MD, Aman Taggar, MD, Zhigang Zhang, PhD, Antonio L. Damato, PhD

“…This facilitates intraoperative placement of permanent brachytherapy seeds in a surgical tumor bed, while minimizing dose to overlying structures. No clinical trial data have yet been published for this device. …”
Get full text

Clinical relevance of loss-of-function mutations of NEMO/IKBKG by Jin Wang, Kexin Shen, Hongxia Lou, Lina Zhou, Yunfei An, Xiaodong Zhao, Yuan Ding

“…Almost all cases of hyper-IgM occurred in patients with EDA-ID. Different structural domains correspond to symptoms with varying degrees of severity. …”
Get full text

Human gut microbiota adaptation to high-altitude exposure: longitudinal analysis over acute and prolonged periods by Xianzong Ma, Changwei Duan, Xiaoying Wang, Yurong Tao, Lang Yang, Yongsheng Teng, Yuanming Pan, Mingjie Zhang, Junfeng Xu, Jianqiu Sheng, Xin Wang, Peng Jin

“…In summary, acute high-altitude exposure caused dramatic changes in gut microbiota, while prolonged exposure led to structural and functional reshaping. These findings enhance our understanding of how high-altitude environments reshape gut microbiota.IMPORTANCEThis study is the first to investigate the impact of high-altitude exposure on gut microbiota adaptation in a large-scale longitudinal cohort. …”
Get full text

Magnetic Resonance Imaging as a Readout of CLN5 Gene Therapy Efficacy in Sheep by Samantha J. Murray, Mustafa M. Almuqbel, Simon A. Felton, Nickolas J. Palmer, Ashley R. Deane, Daniel J. Myall, Reza Shoorangiz, Arsène Ella, Matthieu Keller, David N. Palmer, Tracy R. Melzer, Nadia L. Mitchell

“…Method Sheep treated at a pre‐symptomatic timepoint underwent five T1‐weighted structural MRI scans between 5 and 18 months of age. …”
Get full text

Legal frameworks for blockchain applications: a comparative study with implications for innovation in Europe by Francisco Von Hafe, Francisco Von Hafe, Francisco Von Hafe, Yash Wagle, Federico Guede-Fernández, Federico Guede-Fernández, Ana Paula Giordano, Ana Paula Giordano, Luís Silva, Salomé Azevedo, Salomé Azevedo, Salomé Azevedo

“…This study compares blockchain regulations across six European geographies: Switzerland, Liechtenstein, and Malta (blockchain-specialised regulators) versus the European Union (EU), Estonia, and Portugal (generalist regulators) to map key divergences in legal maturity, asset classification, taxation, anti-money laundering/know-your-customer enforcement, and supervisory structures. A secondary objective is to evaluate how these differences impact the scalability of innovation.MethodsThis study compares blockchain regulations across six European jurisdictions through a three-phase analysis. …”
Get full text