Bis-Iridoid Glycosides and Triterpenoids from <i>Kolkwitzia amabilis</i> and Their Potential as Inhibitors of ACC1 and ACL by Jiang Wan, Ze-Yu Zhao, Can Wang, Chun-Xiao Jiang, Ying-Peng Tong, Yi Zang, Yeun-Mun Choo, Jia Li, Jin-Feng Hu

“…Amabiliacids A (<b>5</b>) and B (<b>6</b>) are 24-nor-ursane-type triterpenoids characterized by an uncommon ∆^11,13(18) transannular double bond. Their chemical structures and absolute configurations were elucidated through spectroscopic data and electronic circular dichroism analyses. …”
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H‐Shaped Anatomical Titanium Plate: Biomechanical Validation and Clinical Application in the Treatment of Complex Posterior Wall/Column Acetabular Fractures by Qiaoli Zhang, Liang Jin, Xiaorui Hao, Weijie Zheng, Fei Zhou, Shuxin Zhang, Tianfeng Li, Xiaohui Xiong, Yihan He, Xiaojie Chen, Jiexin Huang

“…Following anatomic reduction, cyclic loading and destructive experiments were conducted to assess the efficacy of different fixation devices under various loads for the posterior wall and column, as well as their peak load and structural stiffness. Additionally, we retrospectively analyzed the clinical data of 53 patients (46 males, 7 females; mean follow‐up 24.6 ± 3.2 months) with the HTP at our hospital from April 2017 to January 2023. …”
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Les réseaux d’alimentation en eau des pentes de la Croix-Rousse et de la presqu’île de Lyon by Jules Ramona

“…Drawing on a comprehensive collection of data relating to water-related structures (wells, pipes, basins and fountains), the objective of the article is to review the state of knowledge about the modes of water supply on the slopes of the Croix-Rousse and the Presqu’île. …”
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Optical Coherence Tomography Imaging and Angiography of Skull Base Tumors Presenting as a Middle Ear Mass in Clinic by Dorothy W. Pan, Marcela A. Morán, Wihan Kim, Zihan Yang, Brian E. Applegate, John S. Oghalai

“…Optical coherence tomography (OCT) is a noninvasive imaging technique that can image tissue with high resolution in three dimensions, including through structures such as the TM and bone. OCT angiography is also able to assess tissue vascularity. …”
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Bicontinuous Nanophasic Conetworks of Polystyrene with Poly(dimethylsiloxane) and Divinylbenzene: From Macrocrosslinked to Hypercrosslinked Double-Hydrophobic Conetworks and Their... by Anna Petróczy, István Szanka, András Wacha, Zoltán Varga, Yi Thomann, Ralf Thomann, Rolf Mülhaupt, Laura Bereczki, Nóra Hegyesi, Béla Iván

“…The Korsmeyer–Peppas type evaluation of the swelling data indicates hindered Fickian diffusion of both solvents in the conetwork organogels. …”
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Morphological analysis and functional connectivity of the insular in patients with dysphagia after cerebral infarction based on resting-state fMRI by Ming Guo, Bingjie Li, Jun Zhao, Chen Bai, Weiyong Yu, Hongxia Zhang, Haoyuan Li, Yongxue Yuan, Qingsu Zhang, Tong Zhang

“…Resting-state functional magnetic resonance imaging (rs-fMRI) and high-resolution T1-weighted structural imaging data were acquired. Seed-based analysis (using the CONN FC toolbox) was employed to quantify the whole-brain functional connectivity (FC) of the insula, and voxel-based morphometry (VBM) was used to assess gray matter volume changes. …”
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Association between post-PCI vessel fractional flow reserve (vFFR) and optical coherence tomography (OCT) findings: Results from the FAST OCT study by Annemieke C. Ziedses des Plantes, Alessandra Scoccia, Frederik T.W. Groenland, Maria N. Tovar Forero, Mariusz Tomaniak, Janusz Kochman, Wojciech Wojakowski, Pawel Gąsior, Koen Ameloot, Tom Adriaenssens, Wijnand K. den Dekker, Rutger-Jan Nuis, Isabella Kardys, Nicolas M. Van Mieghem, Ernest Spitzer, Joost Daemen

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Curve Behavior of Distal Segments After Posterior‐Only Hemivertebra Resection for Congenital Cervicothoracic Scoliosis by Yang Li, Zezhang Zhu, Wanyou Liu, Saihu Mao, Zhen Liu, Xu Sun, Yong Qiu, Benlong Shi

“…However, the curve behavior of distal non‐structural compensatory curves and its possible mechanisms were unclear. …”
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Mechanism and quantitative traceability of anomalous outflow of unloaded gas from protective layer mining under complex tectonics by Xuexi CHEN, Xingyu CHEN, Jiaying HU, Aitao ZHOU, Jian XIAO, Jihong SUN, Zhilong YAN

“…By coupling simulation analysis of FLAC3D-COMSOL under complex structural stress, the mechanical evolution law and stress relief and permeability enhancement mechanism of protective layer mining are studied. …”
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Les effectifs en langues dans l’enseignement supérieur français : vers une politique linguistique d’ouverture ? by Marcelo Tano

“…Abstract (English) This contribution aims to disclose the main data collected during field surveys carried out in 372 structures in the four most representative sectors of French public higher education that include language courses in their training curricula. …”
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Effects of low wildfire burn severity due to pre-fire shrub thinning on the chaparral soil bacteriome in the Santa Monica Mountains of Southern California by Mariah Macias, Mari R. Irving, Katelyn M. Bandow, Kaitlyn Kim, Cecilia Heredia, Courtney A. Hoskinson, Nina R. Duchild, Michael T. Nicholas, Lindsey M. Marian, Camille K. Sicangco, Karagan L. Smith, Stephen D. Davis, Helen I. Holmlund, Leah T. Stiemsma

“…We predicted the functional bacteriome from the 16S data using PICRUSt2. Relative to high severity soils, low severity soils showed decreased nutrient concentrations, pH, and % organic matter in 2019. …”
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Increased vulnerability to psychological distress and suicidal ideation among transgender women with self-reported disabilities in San Francisco, California by Abtin Shafie, Alexis Salvatore, Riley Shea, Eileen Yu, Oyku Ozyucel, Ansharan Akbar, Bow Suprasert, Erin C. Wilson, Willi McFarland, Kelly D. Taylor, Sean Arayasirikul

“…OBJECTIVE: Research among transgender women has found health, but especially mental health, to be shaped by social inequities and multiple, intersectional, structural vulnerabilities. While some studies have shown that transgender adults are also more likely to have a disability than cisgender adults, few studies have explored this intersection. …”
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Clinical profiles and health-related quality of life changes after treatment in advanced colorectal cancer patients: a nationwide study in China by Hongwei Liu, Ziyao Jia, Huifang Xu, Xiaoyang Wang, Hong Wang, Ruihua Kang, Qiong Chen, Xiaoli Guo, Ranran Qie, Mengfei Zhao, Cheng Cheng, Liyang Zheng, Shuzheng Liu, Yin Liu, Shaokai Zhang, China Working Group on Colorectal Cancer Survey

“…The multivariable regressions and structural equation model (SEM) were used to assess the association between characteristics and HRQOL. …”
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Diagnostics and Treatment of Esophageal Achalasia (Clinical Guidelines of the Russian Gastroenterological Association, Russian Scientific Medical Society of Internal Medicine, Russ... by V. T. Ivashkin, A. S. Trukhmanov, I. V. Maev, O. M. Drapkina, A. I. Martynov, O. A. Storonova, E. A. Godgello, M. P. Korolev, T. L. Lapina, P. V. Pavlov, A. V. Paraskevova, I. A. Tarasova, E. D. Fedorov, A. T. Tskhovrebov, M. P. Shapka, A. L. Shestakov, A. V. Yurasov

“…To analyse the obtained data, the Chicago classification is recommended — it allows to ascertain the type of achalasia, which determines the choice of treatment method and the assessment of the prognosis of the therapy effectiveness. …”
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Repositioning FDA-Approved Sulfonamide-Based Drugs as Potential Carbonic Anhydrase Inhibitors in <i>Trypanosoma cruzi</i>: Virtual Screening and In Vitro Studies by Eyra Ortiz-Pérez, Adriana Moreno-Rodríguez, Timoteo Delgado-Maldonado, Jessica L. Ortega-Balleza, Alonzo González-González, Alma D. Paz-González, Karina Vázquez, Guadalupe Avalos-Navarro, Simone Giovannuzzi, Claudiu T. Supuran, Gildardo Rivera

“…Future studies should focus on structural modifications to improve selectivity. Integrating docking, parasitological, and enzymatic data is crucial for optimizing drug candidates for Chagas disease.…”
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Predicting leakage of the VERCORS mock-up and concrete containment buildings - a digital twin approach by Laurent Charpin, Jessica Haelewyn, Anass Cherki El Idrissi, Julien Niepceron, Benoît Masson, Charles Toulemonde, Guillaume Boulant, Jean-Philippe Mathieu, François Hamon, Sylvie Michel-Ponnelle, Jean-Marie Hénault, Frédéric Taillade, Jean-Luc Adia, Florian Escoffier

“…An important numerical effort has also been made to implement structural computations of the mock-up and to capitalize these computations as well as their post-processing (so as to compare automatically with the monitoring data) in what can be called a digital twin of the mock-up. …”
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Dangerous Glacial Lakes Identification With Property-Spatial Associations in High Mountain Asia From 1990 to 2022 by Hang Zhao, Dan Wang, Lingping An, Juan Cheng, Shuang Wang, Meimei Zhang, Chenglong Tao

“…However, the existing methods rely on the scoring regressions from combinations of glacial lake properties to assess the outburst risks of glacial lakes on a large scale, neglecting the spatial structures of lake scenes and property dependencies which may result in diverging hazard estimates. …”
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METASOMATIC AND MAGMATIC PROCESSES IN THE MANTLE LITHOSPHERE OF THE BIREKTE TERRAIN OF THE SIBERIAN CRATON AND THEIR EFFECT ON THE LITHOSPHERE EVOLUTION by Lidia V. Solov’eva, Tatiana V. Kalashnikova, Sergei I. Kostrovitsky, Alexei V. Ivanov, Stanislav S. Matsuk, Ludmila F. Suvorova

“…Mica and ilmenite contents sharply decrease in garnetized xenolithes, where these two minerals, as soon as olivine and pyroxenes are replaced by garnet.Euhedral, subhedral, sideronitic and porphyraceous structures in garnetless xenoliths suggest the primary magmatic genesis of the rocks. …”
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The Effect of Tangible and Intangible Hotel Caracteristics on Brand Loyalty with the Mediating Role of Perceived Well-Being and Brand Attitude (Case study: 4 And 5 Star Hotels In M... by Zahra Mohamadzadeh, Zahra Mohamoudi

“…The sample members were selected by conducting the convenience sampling sample. The collected data were analyzed using structural equation modeling technique in Amos software. …”
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Molecular and spatial transcriptomic classification of midbrain dopamine neurons and their alterations in a LRRK2G2019S model of Parkinson’s disease by Zachary Gaertner, Cameron Oram, Amanda Schneeweis, Elan Schonfeld, Cyril Bolduc, Chuyu Chen, Daniel Dombeck, Loukia Parisiadou, Jean-Francois Poulin, Rajeshwar Awatramani

“…We developed an optimized pipeline for single-nuclear RNA sequencing (snRNA-seq) and generated a high-resolution hierarchically organized map revealing 20 molecularly distinct DA neuron subtypes belonging to three main families. We integrated this data with spatial MERFISH technology to map, with high definition, the location of these subtypes in the mouse midbrain, revealing heterogeneity even within neuroanatomical sub-structures. …”
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