Emerging roles of the cancerous inhibitor of protein phosphatase 2A (CIP2A) in ovarian cancer by Alice Filipe, Sayeh Saravi, Denis Mustafov, Suzana Panfilov, Simran Banger, Seyedehnajmeh Mousavikivaj, Maria Braoudaki, Senthilkumar Kailasam, Yasser Riazalhosseini, Michelle A. Sahai, Fotios Drenos, Cristina Sisu, Emmanouil Karteris

“…High CIP2A expression reduces both overall-and progression-free survival, whereas an R530T mutation is predicted to cause structural destabilisation of the CIP2A dimer. We also provide evidence for microRNA (miRNA) and mRNA target interactions with CIP2A. …”
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Integrating multi-model frameworks to unravel the spatiotemporal dynamics of flash floods in the Tianshan Mountain, China by Biao Zhang, Haiyan Fang, Guotao Zhang, Songqing Li, Shufang Wu, Kadambot H.M. Siddique

“…Subsequently, the Partial Least Squares Structural Equation (PLS-SEM) was used to explore the direct and indirect influence pathways among driving factors. …”
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Exploring the sequential mediation model of coping humor, self-esteem, resilience, and subjective well-being among Taiwanese university students by Chin-Wen Liao, Chih-Yu Ting, Yao-Chung Cheng, Kai-Jie Chen, An-Sheng Liu, Tzu-Ju Hsueh

“…Analyses were conducted using IBM SPSS 27.0 and SmartPLS 4.0, applying descriptive statistics, Pearson correlation, t-tests, ANOVA, and Partial Least Squares Structural Equation Modeling (PLS-SEM). Results confirmed that self-esteem and resilience significantly mediate the relationship between coping humor and subjective happiness, validating the proposed model. …”
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Resistin Is Increased in Periodontal Cells and Tissues: In Vitro and In Vivo Studies by Andressa V. B. Nogueira, Marjan Nokhbehsaim, Sema Tekin, Rafael S. de Molon, Luis C. Spolidorio, Svenja Memmert, Anna Damanaki, Andreas Jäger, Sigrun Eick, James Deschner, Joni A. Cirelli

“…The periodontitis group demonstrated significant bone loss, an increase in the number of inflammatory cells and vascular structures, an increase in resistin expression and synthesis, and a decrease in the expression of adiponectin, leptin, and its functional receptor. …”
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Sustainable transformation of cotton stalk waste as a biochar-based copper-silicon composite for chromium (VI) detoxification by Sana Shakil, Salah Ud Din, Khawaja Ansar Yasin, Muhammad Sheraz Ahmad, Muhammad Imran, Abdurahman Hajinur Hirad, Jamoliddin Razzokov, Sirajul Haq

“…Characterization techniques, including XRD, FTIR, EDX, SEM, TEM, XPS, and PZC analysis, confirmed the material's structural and chemical properties. Peaks at 153 eV (Si2p) and 932.1 eV (Cu 2p) validated the presence of silicon and copper, while a peak at 529.9 eV indicated Cr₂O₃/Cr(OH)₃ formation after adsorption. …”
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Numerical Simulation of Thermal Fields and Microstructure Evolution in SLM of Fe₃₂Cr₃₃Ni₂₉Al₃Ti₃ Alloy by Xuyun Peng, Xiaojun Tan, Haibing Xiao, Wei Zhang, Liang Guo, Wei Tan, Jian Huang, Chaojun Ding, Yushan Yang, Jieshun Yang, Haitao Chen, Qingmao Zhang

“…Fabricating eutectic high-entropy alloys (EHEAs) via selective laser melting (SLM) presents significant potential for advanced structural applications. This study explores the microstructural evolution of Fe₃₂Cr₃₃Ni₂₉Al₃Ti₃ EHEAs fabricated by SLM under varying laser powers. …”
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Census of Blue Straggler Stars in Distant Open Clusters and Maximum Fractional Mass Excess of Open Cluster Blue Straggler Stars by Qian Cui, Zhihong He, Shunhong Deng, Liming Peng, Chunyan Li, Yangping Luo, Kun Wang

“…We identified blue straggler stars (BSSs) in 53 open clusters utilizing data from Gaia DR3. Most of these clusters are situated in the outer regions of the Galactic disk, encompassing structures such as the warp and the Outer arm. …”
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Comparative risk of QTc prolongation induced by second-generation antipsychotics in the real world: retrospective cohort study based on a hospital information system by Luyao He, Wenjuan Yu, Huiqing Song, Lujin Li, Yifeng Shen, Lei Zhang, Huafang Li

“…A marginal structural Cox model was used to compare the hazard ratios for QTc prolongation associated with various SGAs. …”
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Hmgb2 improves astrocyte to neuron conversion by increasing the chromatin accessibility of genes associated with neuronal maturation in a proneuronal factor-dependent manner by Priya Maddhesiya, Tjasa Lepko, Andrea Steiner-Mezzardi, Julia Schneider, Veronika Schwarz, Juliane Merl-Pham, Finja Berger, Stefanie M. Hauck, Lorenza Ronfani, Marco Bianchi, Tatiana Simon, Anthodesmi Krontira, Giacomo Masserdotti, Magdalena Götz, Jovica Ninkovic

“…Using this culture system, we show that chromatin structural protein high mobility group box 2 (HMGB2) regulates the direct conversion rate downstream of the growth factor combination. …”
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‘When I tried to explain, they shouted back at me!’: exploring how community pharmacists navigate tensions implementing antimicrobial stewardship in Vietnam by Duy Trinh Hoang, Shannon McKinn, Dorothy Drabarek, Thao Thu Trieu, Van Thuy Pham, Yen Ngoc Pham, Thai Hung Cao, Hung Mai Tran, Greg J. Fox, Thu-Anh Nguyen, Sarah Bernays

“…This qualitative analysis draws on data from 24 in-depth interviews with licensed community pharmacists in Vietnam. …”
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System Design and Launch of a Hybrid Rocket with a Star-Fractal Swirl Fuel Grain Toward an Altitude of 15 km by Atsushi Takano, Keita Yoshino, Yuki Fukushima, Ryuta Kitamura, Yuki Funami, Kenichi Takahashi, Akiyo Takahashi, Yoshihiko Kunihiro, Makoto Miyake, Takuma Masai, Shizuo Uemura

“…In addition to the engine, other components were also improved, such as through the incorporation of lightweight structures, low-shock separation devices, a high-reliability telemetry device, and a data logger, while keeping costs low. …”
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Comparative Immunogenicity in Rabbits of the Polypeptides Encoded by the 5′ Terminus of Hepatitis C Virus RNA by Irina Sominskaya, Juris Jansons, Anastasija Dovbenko, Natalia Petrakova, Ilva Lieknina, Marija Mihailova, Oleg Latyshev, Olesja Eliseeva, Irina Stahovska, Inara Akopjana, Ivars Petrovskis, Maria Isaguliants

“…Recent studies on the primate protection from HCV infection stressed the importance of immune response against structural viral proteins. Strong immune response against nucleocapsid (core) protein was difficult to achieve, requesting further experimentation in large animals. …”
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Advancements in Optical Fiber Sensors for pH Measurement: Technologies and Applications by Alaa N. D. Alhussein, Mohammed R. T. M. Qaid, Timur Agliullin, Bulat Valeev, Oleg Morozov, Airat Sakhabutdinov, Yuri A. Konstantinov

“…Recent advancements have also enabled automation in data analysis and improvements in remote sensing capabilities. …”
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Application of Convolutional Neural Networks in an Automatic Judgment System for Tooth Impaction Based on Dental Panoramic Radiography by Ya-Yun Huang, Yi-Cheng Mao, Tsung-Yi Chen, Chiung-An Chen, Shih-Lun Chen, Yu-Jui Huang, Chun-Han Chen, Jun-Kai Chen, Wei-Chen Tu, Patricia Angela R. Abu

“…<b>Background/Objectives:</b> Panoramic radiography (PANO) is widely utilized for routine dental examinations, as a single PANO image captures most anatomical structures and clinical findings, enabling an initial assessment of overall dental health. …”
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Incorporating the voice of young people in mental health research: reflections from three lived experience advisory panels in Latin America by Liliana Hidalgo-Padilla, Daniela Ramirez-Meneses, Karen Ariza-Salazar, Santiago Cesar Lucchetti, Natividad Olivar, Diliniya Stanislaus Sureshkumar, Catherine Fung, Luis Ignacio Brusco, Carlos Gómez-Restrepo, José Miguel Uribe-Restrepo, Stefan Priebe, Francisco Diez-Canseco

“…Future efforts should focus on overcoming structural limitations and fostering equitable collaboration, emphasising the need for youth perspectives in mental health research, particularly in low- and middle-income countries.…”
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Impact of Early-Life Brain Injury on Gut Microbiota Composition in Rodents: Systematic Review with Implications for Neurodevelopment by Vanessa da Silva Souza, Raul Manhães-de-Castro, Sabrina da Conceição Pereira, Beatriz Souza de Silveira, Caio Matheus Santos da Silva Calado, Henrique José Cavalcanti Bezerra Gouveia, Jacques-Olivier Coq, Ana Elisa Toscano

“…Eligible studies focused on evaluating the microbiota alterations and related gut–brain axis markers at the neonatal or post-weaning stages. The data extraction and synthesis followed PRISMA guidelines. …”
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Genome-Wide Identification of the HSP Gene Family in Penaeus japonicus and Their Expression Characteristics During Development Stages by Xueqiong BIAN, Xianyun REN, Junxia WANG, Shaoting JIA, Jianjun GUO, Kuangcheng ZHAO, Ping LIU, Jian LI, Jitao LI

“…Fifteen members of the hsp gene family were identified from the whole genome of P. japonicus via bioinformatics analysis, and their gene structures, motif compositions, chromosome localizations, and phylogenetic characteristics were analyzed. …”
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Short- and long-term outcomes of Impella-protected, high-risk, elective PCI in patients with multivessel coronary disease and low ejection fraction — Polish Impella Registry by Wojciech J. Skorupski, Arkadiusz Pietrasik, Aleksandra Gąsecka, Jerzy Sacha, Tomasz Pawłowski, Gabriel Bielawski, Wojciech Balak, Adam Sukiennik, Paulina Burzyńska, Adam Witkowski, Mateusz Warniełło, Łukasz Rzeszutko, Stanisław Bartuś, Artur Pawlik, Mateusz Kaczyński, Robert Gil, Wiktor Kuliczkowski, Krzysztof Reczuch, Marcin Protasiewicz, Jacek Legutko, Paweł Kleczyński, Piotr Wańczura, Sebastian Gurba, Anna Kochanowska, Michał Łomiak, Maciej Krajsman, Włodzimierz Skorupski, Maciej Zarębiński, Piotr Pawluczuk, Szymon Włodarczak, Adrian Włodarczak, Krzysztof Ściborski, Artur Telichowski, Mieszko Pluciński, Jarosław Hiczkiewicz, Karolina Konsek, Michał Hawranek, Mariusz Gąsior, Jan Peruga, Marcin Fiutowski, Robert Romanek, Piotr Kasprzyk, Dariusz Ciećwierz, Andrzej Ochała, Wojciech Wojakowski, Janusz Kochman, Maciej Lesiak, Marek Grygier

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Comprehensive analysis of the electronic, thermodynamic, and spectroscopic properties of a Cu(II)-based complex with 1,10-phenanthroline and L-glutamine by Marinaldo V. Souza Junior, João G. Oliveira Neto, Walajhone O. Pereira, Jéssica A.O. Rodrigues, Jailton R. Viana, Aramys S. Reis, Mateus R. Lage, Guilherme G.C. Carvalho, Cláudia O. Pessoa, Adenilson O. dos Santos, Francisco F. de Sousa

“…A computational analysis of the intermolecular interactions using Hirshfeld surfaces was also performed, which demonstrated that the H⋯O/O⋯H and H⋯H interactions are mainly responsible for the structural and thermal stability of the complex. The calculated intramolecular vibration bands showed a good correlation with the experimental Raman and infrared (IR) data, although solvation effects caused some wavenumber shifts. …”
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Dolphin Pituitary Gland: Immunohistochemistry and Ultrastructural Cell Characterization Following a Novel Anatomical Dissection Protocol and Non-Invasive Imaging (MRI) by Paula Alonso-Almorox, Alfonso Blanco, Carla Fiorito, Eva Sierra, Cristian Suárez-Santana, Francesco Consolli, Manuel Arbelo, Raiden Grandía Guzmán, Ignacio Molpeceres-Diego, Antonio Fernández Gómez, Javier Almunia, Ayoze Castro-Alonso, Antonio Fernández

“…MRI allowed visualization of the gland’s anatomy and its spatial relationship with the hypothalamus and surrounding structures. A modified skull-opening and pituitary extraction protocol ensured the preservation of the adenohypophysis and neurohypophysis for detailed analysis. …”
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