Identification of multiple genomic alterations and prediction of neoantigens from circulating tumor cells at the single-cell level by Xiaochen Gao, Xinyu Li, Weize Xu, Ming Jiao, Yu Guo, Jiajia Wang, Weihao Wang, Jiling Feng, Qianqian Guo, Chengchao Wu, Taiyu Zhang, Yuqin Yang, Da Lin

“…In the PDX model, integrating data from seven CTCs captures 88.7% of SNPs and INDELs, and 75.0% of structural variants present in tumor tissue. …”
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Tackling Paradoxes and Double Binds for a Healthier Workplace: Insights from the Early COVID-19 Responses in Quebec and Ontario by Daniel Côté, Amelia León, Ai-Thuy Huynh, Jessica Dubé, Ellen MacEachen, Pamela Hopwood, Marie Laberge, Samantha Meyer, Shannon Majowicz, Meghan K. Crouch, Joyceline Amoako

“…This study presents a secondary analysis of qualitative data on paradoxes and double binds (PDBs) experienced by precarious essential workers in Canada who interacted with the public and their supervisors. …”
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Prevalence and environmental abundance of the TSET complex in cosmopolitan algal groups by Mathias Penot-Raquin, Mandeep Sivia, Kelly M. Fafoumi, Raegan Larson, Richard G. Dorrell, Joel B. Dacks

“…Finally, diatom TSET genes are detectable in meta-transcriptomic data from Tara Oceans, suggesting functional roles in the wild. …”
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Multimodal gradients unify local and global cortical organization by Yezhou Wang, Nicole Eichert, Casey Paquola, Raul Rodriguez-Cruces, Jordan DeKraker, Jessica Royer, Donna Gift Cabalo, Hans Auer, Alexander Ngo, Ilana R. Leppert, Christine L. Tardif, David A. Rudko, Robert Leech, Katrin Amunts, Sofie L. Valk, Jonathan Smallwood, Alan C. Evans, Boris C. Bernhardt

“…Here, we present an approach to integrate inter- and intra-areal similarities of microstructure, structural connectivity, and functional interactions. …”
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Unveiling the powerhouse: ASCL1-driven small cell lung cancer is characterized by higher numbers of mitochondria and enhanced oxidative phosphorylation by Anna Solta, Büsra Ernhofer, Kristiina Boettiger, Christian Lang, Zsolt Megyesfalvi, Theresa Mendrina, Dominik Kirchhofer, Gerald Timelthaler, Beata Szeitz, Melinda Rezeli, Clemens Aigner, Arvand Haschemi, Lukas W. Unger, Balazs Dome, Karin Schelch

“…Methods Metabolic alterations were analyzed using proteomic data. Structural and functional differences of mitochondria were investigated using qPCR, flow cytometry, confocal imaging, and transmission electron microscopy and seahorse assays. …”
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The Mediator Role of Depression in the Successful Aging and Death Anxiety in Middle-Aged and Older People With Hypertension by Xiaoping Li, Lu Sun, Liu Yang, Congzhi Wang, Ting Yuan, Huanhuan Wei, Yunxiao Lei, Jing Li, Mingming Liu, Dongmei Zhang, Ying Hua, Haiyang Liu, Lin Zhang

“…Pearson Correlation Analysis and Regression analysis were performed in the data analysis. In addition, AMOS was used to analyze the mediator variable effects. …”
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Technological Assessment and Predictive Modeling of Probiotic Lactose-Free Fermented Milk with <i>Lacticaseibacillus paracasei</i> GV17 by Taynan Jonatha Neves Costa, Isabella Maciel Costa, Larissa Mirelle Mendes Magalhães, Marcelo Resende de Souza, Gabriel Augusto Marques Rossi, Bruna Maria Salotti-Souza, Camila Argenta Fante

“…Regarding technological characteristics, syneresis decreased by 8.90% after 28 days, indicating greater structural stability, while water retention capacity remained constant. …”
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Decoding Schizophrenia: How AI-Enhanced fMRI Unlocks New Pathways for Precision Psychiatry by Valeria Di Stefano, Martina D’Angelo, Francesco Monaco, Annarita Vignapiano, Vassilis Martiadis, Eugenia Barone, Michele Fornaro, Luca Steardo, Marco Solmi, Mirko Manchia, Luca Steardo

“…Moreover, ethical considerations surrounding data integrity, algorithmic transparency, and patient individuality must guide AI’s integration into psychiatry. …”
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Evidential deep learning-based drug-target interaction prediction by Yanpeng Zhao, Yuting Xing, Yixin Zhang, Yifei Wang, Mengxuan Wan, Duoyun Yi, Chengkun Wu, Shangze Li, Huiyan Xu, Hongyang Zhang, Ziyi Liu, Guowei Zhou, Mengfan Li, Xuanze Wang, Zhengshan Chen, Ruijiang Li, Lianlian Wu, Dongsheng Zhao, Peng Zan, Song He, Xiaochen Bo

“…EviDTI integrates multiple data dimensions, including drug 2D topological graphs and 3D spatial structures, and target sequence features. …”
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Optimization of Protein Extraction from Rapeseed Oil Cake by Dephenolization Process for Scale-Up Application Using Artificial Neural Networks by Branislava Đermanovć, Jelena Vujetić, Tea Sedlar, Danka Dragojlović, Ljiljana Popović, Predrag Kojić, Pavle Jovanov, Bojana Šarić

“…In this study, the effects of dephenolization on the structural, physicochemical, and functional properties of rapeseed protein isolate obtained from defatted rapeseed cake were investigated through four different protocols. …”
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Impact-induced energy release of typical HCP metal/PTFE/W reactive materials: Experimental study and predictive modeling via machine learning by Zhenwei Zhang, Weixi Tian, Tianyi Wang, Zhiyuan Liu, Yansong Yang, Chao Ge, Lei Guo, Yuan He, Chuanting Wang, Yong He

“…Zirconium, titanium, and other hexagonally close-packed (HCP) metals and their alloys are representative high specific strength, high reaction enthalpy, and high thermal conductivity structural materials. In this study, two typical HCP metals, zirconium, and titanium, were applied to reactive materials (RMs) to prepare Zr/PTFE/W RMs and Ti/PTFE/W RMs, validating the feasibility of HCP metal/PTFE/W RMs. …”
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Study on residual strength of oil and gas pipeline with corrosion defects under bending load by Song Chenxi, Shu Jie, Chen Han, Shi Tong, Wu Xiatong, Liu Xiaoben

“…These challenges include structural defects, geological disasters such as earthquakes, landslides, debris flows, and land subsidence, as well as external forces such as dynamic impact forces, shear forces, extrusion forces, and uneven settlement forces. …”
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Synergistic Enhancement of Rhodamine B Adsorption by Coffee Shell Biochar Through High-Temperature Pyrolysis and Water Washing by Xurundong Kan, Yao Suo, Bingfei Shi, Yan Zheng, Zaiqiong Liu, Wenhui Ma, Xianghong Li, Jianqiang Zhang

“…The adsorption kinetics conformed to a pseudo-second-order model, indicating chemisorption, and the equilibrium data fit the Langmuir model, suggesting monolayer coverage. …”
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Valorization of Food Waste: Extracting Bioactive Compounds for Sustainable Health and Environmental Solutions by Nikša Bekavac, Korina Krog, Ana Stanić, Dunja Šamec, Anita Šalić, Maja Benković, Tamara Jurina, Jasenka Gajdoš Kljusurić, Davor Valinger, Ana Jurinjak Tušek

“…Studies lacking empirical data, not addressing the extraction or application of bioactives, or published in languages other than English were excluded.…”
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Hospital Context Determinants of Variability in Healthcare-Associated Infection Prevalence: Multi-Level Analysis by Rui Malheiro, André Amaral Gomes, Carlos Fernandes, Ana Fareleira, Ana Lebre, Dulce Pascoalinho, João Gonçalves-Pereira, José-Artur Paiva, Rita Sá-Machado

“…The study variables included patient, structural, and process variables, tested as risk factors, with patients clustered in hospitals. …”
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Functional neuroplasticity in chronic post-stroke aphasia following a singing intervention in a cross-over randomised trial by Noelia Martínez-Molina, Anni Pitkäniemi, Sini-Tuuli Siponkoski, Nella Moisseinen, Linda Kuusela, Sari Laitinen, Essi-Reetta Särkämö, Johanna Pekkola, Susanna Melkas, Gottfried Schlaug, Boris Kleber, Aleksi J. Sihvonen, Teppo Särkämö

“…Abstract Group-based singing has been shown to improve language outcomes and induce structural neuroplasticity in chronic post-stroke aphasia (PSA). …”
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Surface patterning for multi-scale strain analysis of in-situ SEM mechanical experiments by Bin Zhang, Xianjue Ye, Jin Wang, Yuefei Zhang, Ze Zhang

“…Such experimental analyses offer an opportunity to further explore multi-scale strain heterogeneity in some advanced structural materials and provide reliable experimental verification for material mechanics simulations.…”
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Crafting the Organic Mindset Through Attitude: A PLS-SEM Approach by Kalisri L. Aravindan, Aysa Siddika, T. Ramayah, Farheen S. Wani, Sanmugam Annamalah, N. Ilhavenil, Lylia Hamdan Sunita

“…The study utilized purposive sampling, and data analysis was conducted by Partial Least Square, Structural Equation Modeling (PLS-SEM). …”
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The influence of public health organization on response to the COVID-19 pandemic in four Canadian provinces: A comparative qualitative analysis by Susan Usher, Sara Allin, Lara Gautier, Katherine Fierlbeck, Veena Sriram, Aidan Bodner, Camille Trapé, Leah Shipton, Alessia Montecalvo, Peter Berman

“…All public health systems relied on healthcare resources for testing programs despite differences in the integration of public health under healthcare governance structures; centralization of healthcare governance was a facilitator. …”
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Environmental behavior of microplastic - heavy metal synergistic contamination in a typical urban-rural river network by Kaihang Zhang, Jian Huang, Jiamei Zhang, Hua Zhang, Shanshan Xi

“…Based on the correlation analysis and structural equation model, the polymer type of MPs (path coefficient = 0.3798) and the content of HMs in water (path coefficient = 0.3391) were the significant influence drivers on the adsorption of HMs by MPs. …”
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