Large-scale annotation of biochemically relevant pockets and tunnels in cognate enzyme–ligand complexes by O. Vavra, J. Tyzack, F. Haddadi, J. Stourac, J. Damborsky, S. Mazurenko, J. M. Thornton, D. Bednar

“…Abstract Tunnels in enzymes with buried active sites are key structural features allowing the entry of substrates and the release of products, thus contributing to the catalytic efficiency. …”
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Impacts of local, provincial, and federal immigration policies on health and social services access among women with precarious immigration status by Hanah Damot, Shaina Schafers, Mei-ling Wiedmeyer, Stefanie Machado, Elmira Tayyar, Padmini Thakore, Ruth Lavergne, Shira Miriam Goldenberg, the IRIS team

“…., non-status immigrants, refugee claimants, students, temporary foreign workers, visitors, and other migrants) face structural barriers to health and social services access. …”
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Human immunodeficiency virus accelerates brain aging and disrupts the trajectory of glymphatic clearance in aging brain by Benedictor Alexander Nguchu, Benedictor Alexander Nguchu, Jing Zhao, Yu Lu, Yifei Han, Han Jin, Xiaoxiao Wang, Hongjun Li, Peter Shaw

“…ResultsOur results showed that subjects with HIV had increased brain-PAD in several brain structures compared to those who were HIV-negative, suggesting underlying neuropathology associated with HIV. …”
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Analysis of the dependence of the levels of markers of early kidney damage — cytokines KIM-1 and TGF-β1 in children with juvenile idiopathic arthritis by L.I. Vakulenko, S.V. Samsonenko

“…The purpose was to analyze the risk factors for structural tubular lesions by studying the level of kidney injury molecule-1 (KIM-1) and transforming growth factor β1 (TGF-β1) in children with JIA, depending on the characteristics of the clinical course of the disease and the treatment received. …”
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Microvascular flow imaging of fibroids: A prospective pilot study by Marissa Frijlingh, Barbara Stoelinga, Robert A. deLeeuw, Wouter J. K. Hehenkamp, Jos W. R. Twisk, Thierry van denBosch, Lynda J. M. Juffermans, Judith A. F. Huirne

“…Using 2D MV‐flow different vascular structures were visible in detail, in contrary to using 2D and 3D power Doppler. …”
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The Use of Enhanced External Counterpulsation in the Treatment of Patients with Coronary Artery Disease by K. S. Karaganov, A. S. Lishuta, Y. N. Belenkov

“…To study the effect of the EECP course on exercise tolerance, quality of life, structural and functional parameters of blood vessels in patients with verified stable CAD complicated by CHF.Material and methods. …”
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MYH1 deficiency disrupts outer hair cell electromotility, resulting in hearing loss by Jinsei Jung, Sun Young Joo, Hyehyun Min, Jae Won Roh, Kyung Ah Kim, Ji-Hyun Ma, John Hoon Rim, Jung Ah Kim, Se Jin Kim, Seung Hyun Jang, Young Ik Koh, Hye-Youn Kim, Ho Lee, Byoung Choul Kim, Heon Yung Gee, Jinwoong Bok, Jae Young Choi, Je Kyung Seong

“…Here, we investigated the role of MYH1 in outer hair cells (OHCs), crucial structures in the organ of Corti responsible for regulating cochlear amplification. …”
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Metagenomics combined with activity-based proteomics point to gut bacterial enzymes that reactivate mycophenolate by Joshua B. Simpson, Josh J. Sekela, Amanda L. Graboski, Valentina B. Borlandelli, Marissa M. Bivins, Natalie K. Barker, Alicia A. Sorgen, Angie L. Mordant, Rebecca L. Johnson, Aadra P. Bhatt, Anthony A. Fodor, Laura E. Herring, Hermen Overkleeft, John R. Lee, Matthew. R. Redinbo

“…GUS enzymes demonstrate distinct substrate preferences based on their structural features, and gut microbial GUS enzymes that reactivate MPA have not been identified. …”
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The Cosmic Evolution Early Release Science Survey (CEERS) by Steven L. Finkelstein, Micaela B. Bagley, Pablo Arrabal Haro, Mark Dickinson, Henry C. Ferguson, Jeyhan S. Kartaltepe, Dale D. Kocevski, Anton M. Koekemoer, Jennifer M. Lotz, Casey Papovich, Pablo G. Pérez-González, Nor Pirzkal, Rachel S. Somerville, Jonathan R. Trump, Guang Yang, L. Y. Aaron Yung, Adriano Fontana, Andrea Grazian, Norman A. Grogin, Lisa J. Kewley, Allison Kirkpatrick, Rebecca L. Larson, Laura Pentericci, Swara Ravindranath, Stephen M. Wilkins, Omar Almaini, Ricardo O. Amorín, Guillermo Barro, Rachana Bhatawdekar, Laura Bisigello, Madisyn Brooks, Véronique Buat, Fernando Buitrago, Denis Burgarella, Antonello Calabrò, Marco Castellano, Yingjie Cheng, Nikko J. Cleri, Justin W. Cole, M. C. Cooper, Olivia R. Cooper, Luca Costantin, Isa G. Cox, Darren Croton, Emanuele Daddi, Kelcey Davis, Avishai Dekel, David Elbaz, Vital Fernández, Seiji Fujimoto, Giovanni Gandolfi, Jonathan P. Gardner, Eric Gawiser, Mauro Giavalisco, Carlos Gómez-Guijarro, Yuchen Guo, Ansh R. Gupta, Nimish P. Hathi, Santosh Harish, Aurélien Henry, Michaela Hirschmann, Weida Hu, Taylor A. Hutchison, Kartheik G. Iyer, Anne E. Jaskot, Saurabh W. Jha, Intae Jung, Susan A. Kassin, Vasily Kokorev, Peter Kurczynski, Gene C. K. Leung, Mario Llerena, Arianna S. Long, Ray A. Lucas, Shiying Lu, Elizabeth J. McGrath, Daniel H. McIntosh, Emiliano Merlin, Bahram Mobasher, Alexa M. Morales, Lorenzo Napolitano, Fabio Pacucci, Viraj Pandya, Marc Rafelski, Giulia Rodighiero, Caitlin Rose, Paola Santini, Lise-Marie Seillé, Raymond C. Simons, Lu Shen, Amber N. Straughn, Sandro Tacchella, Anthony J. Taylor, Brittany N. Vanderhoof, Jesús Vega-Ferrero, Benjamin J. Weiner, Christopher N. A. Willmer, Peixin Zhu, Eric F. Bell, Stijn Wuyts, Benne W. Holwerda, Xin Wang, Weichen Wang, Jorge A. Zavala, (CEERS collaboration)

“…CEERS targets the Hubble Space Telescope–observed region of the Extended Groth Strip field, supported by a rich set of multiwavelength data. CEERS facilitated immediate community science in both of the extragalactic core JWST science drivers “First Light” and “Galaxy Assembly,” including: (1) the discovery and characterization of large samples of galaxies at z  ≳ 10 from  ∼90 arcmin ^2 of NIRCam imaging, constraining their abundance and physical nature; (2) deep spectra of  >1000 galaxies, including dozens of galaxies at 6 <  z  < 10, enabling redshift measurements and constraints on the physical conditions of star formation and black hole growth via line diagnostics; (3) quantifying the first bulge, bar, and disk structures at z  >  3; and (4) characterizing galaxy mid-IR emission with MIRI to study dust-obscured star formation and supermassive black hole growth at z  ∼ 1–3. …”
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Quantitative infrared detection methods for debonding in concrete-filled steel tubes during the hydration heat phase by Haonan Cai, Chongsheng Cheng, Hong Zhang, Jianting Zhou

“…Conducting rapid quantitative debonding detection after the completion of Concrete-filled steel tube (CFST) pouring is crucial for the timely identification and repair of potential structural issues. Currently, there is a lack of an infrared detection method that can perform quantitative detection specifically during the construction phase of CFST. …”
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Algorithm for analyzing randomness in point patterns by Tony Sampaio, Jorge Rocha, Cláudia M. Viana, Silvana Camboin, Fábio Marcelo Breunig, Edenilson Nascimento, Elaine de Cacia de Lima Frick

“…. • Automated scripts for structuring data, calculating expected and observed values, and applying the chi-square goodness-of-fit test for statistical analysis. • Advanced spatial analysis using chi-square goodness of fit coupled with and without Bonferroni correction, providing deeper insight into the study of the effect of spatial phenomena on the distribution of point events.…”
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A Narrative Review on Advancing Pediatric Oral Health: Comprehensive Strategies for the Prevention and Management of Dental Challenges in Children by Sung-Ying Han, Chia-Lin Chang, Yung-Li Wang, Ching-Shuen Wang, Wei-Ju Lee, Thi Thuy Tien Vo, Yuh-Lien Chen, Chueh-Yi Cheng, I-Ta Lee

“…Oral health is fundamental to overall well-being, especially in childhood, when dental structures and lifelong habits are established. This review provides a comprehensive analysis of children’s dental development, common oral health challenges, and evidence-based preventive strategies. …”
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Water resource utilization and future supply–demand scenarios in energy cities of semi-arid regions by Dong Wang, Kai Li, Hengji Li, Yaozong Zhang, Tonglin Fu, Linchan Sun, Yun Wang, Jianxiang Zhang

“…The future water demand of various sectors was simulated and projected, and the supply–demand balance under different socioeconomic and climate scenarios was analyzed using the Shared Socioeconomic Pathways framework combined with climate model data. This research addresses the gap in the existing literature concerning the analysis of water supply–demand structures in energy cities under climate change and provides scientific support for regional sustainable development. …”
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17p13.1 Deletion in Small B-cell Lymphocytic Lymphomas: A Prognostic Factor and Diagnostic Approach by Andreea-Georgiana STOICA, Miruna CRISTIAN, Mariana ASCHIE, Anca-Florentina MITROI, Georgiana-Camelia COZARU, Gabriela-Izabela BALTATESCU, Madalina BOSOTEANU, Mihaela-Maria GHINEA

“…B-cell small lymphocytic lymphoma (B-SLL) belongs to the category of indolent non-Hodgkin's lymphomas and is defined by the proliferation of mature, inert B lymphocytes and their accumulation in lymphoid structures. Although it is classified as the same entity as chronic lymphocytic leukemia (B-CLL), according to the World Health Organization and the International B-CLL Task Force [1, 2], there is little data on the management of lymphocytic lymphoma, accounting for only 10-15% of B-CLL/SLL cases [3, 4]. …”
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The Interaction Between Self-Efficacy, Fear of Failure, and Entrepreneurial Passion: Evidence from Business Students in Emerging Economies by Elizabeth Emperatriz García-Salirrosas, Dany Yudet Millones-Liza, Rafael Fernando Rondon-Eusebio, Jorge Alberto Esponda-Pérez, Eulalia Elizabeth Salas-Tenesaca, Reinaldo Armas-Herrera, María Fernanda Zumba-Zúñiga

“…Scales from renowned researchers were used, which were translated and semantically validated in Spanish to measure the three variables. The data were analyzed using structural equation modeling with PLS. …”
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Using Steel Fiber-Reinforced Concrete Precast Panels for Strengthening in Shear of Beams: An Experimental and Analytical Investigation by Pitcha Jongvivatsakul, Linh V. H. Bui, Theethawachr Koyekaewphring, Atichon Kunawisarut, Narawit Hemstapat, Boonchai Stitmannaithum

“…An experimental program of RC beams strengthened by using SFRC panels, which were attached to both sides of the beams, is carried out to investigate the effects of fiber volume fraction, connection type, and number and diameter of bolts on the structural responses of the retrofitted beams. The current shear resisting model is also employed to discuss the test data considering shear contribution of SFRC panels. …”
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Seabed Liquefaction Risk Assessment Based on Wave Spectrum Characteristics: A Case Study of the Yellow River Subaqueous Delta, China by Hongan Sun, Jishang Xu, Zhenhuan Tian, Lulu Qiao, Zhixing Luan, Yaxin Zhang, Shaotong Zhang, Xingmin Liu, Guangxue Li

“…Seabed liquefaction induced by wave loading poses considerable risks to marine structures and requires careful consideration in marine engineering design and construction. …”
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WETLAND AND BIOCULTURAL HERITAGE REGENERATION THROUGH THEMATIC ECOLOGICAL TOURISM PRACTICE: THE CASE OF PATAN SUB-DISTRICT, KHUN TAN DISTRICT, CHIANG RAI, THAILAND by Siripen YIAMJANYA, Kannapat KANKAEW, Bussaba SITIKARN, Parinya NAKPATHOM, Ali Mohsin Salim Ba AWAIN, Teerarat JABJAINAI

“…The analytic hierarchy process (AHP) was employed to rank the criteria for ecological tourism development. The structural equation modelling (SEM), as a quantitative approach, was used to foster the factors collected from the focus group. …”
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The impact of human resource management on irrigation and drainage management in Indonesia by Khalisah Hayatuddin, Asel Mohmuod, Ainur O. Ongdash, Seyed Saeed Asghari Zonouz, Shukur-Ali Ataev

“…Significant regional variations were observed, with Java demonstrating consistently higher performance scores compared to other regions. Structural equation modelling indicated that organisational culture (β = 0.412) and leadership style (β = 0.376) significantly influenced HRM effectiveness. …”
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Cerebral vascular malformations: pathogenesis and therapy by Qiheng He, Ran Huo, Yingfan Sun, Zhiyao Zheng, Hongyuan Xu, Shaozhi Zhao, Yang Ni, Qifeng Yu, Yuming Jiao, Wenqian Zhang, Jizong Zhao, Yong Cao

“…Traditionally viewed as congenital conditions with structural abnormalities, CVMs have been treated primarily through resection, embolization, and stereotactic radiosurgery. …”
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