Evidence of slab tearing on an inherited Mesozoic rift transfer fault in the Betic Cordillera by Antonio Pedrera, Juan Díaz-Alvarado, Antonio Azor, Andrés Folguera, Luis González-Menéndez, Jesús García-Senz, Pedro Pablo Hernaiz-Huerta, Ana Ruiz-Constán, Carlos Marín-Lechado, Adrià Ramos, Berta López-Mir, Carmen Rodríguez, Roberto Jiménez-Borrego, Károly Hidas

“…Our findings demonstrate how inherited rift-related structures can drive slab tearing and asthenospheric upwelling, shaping the spatial and temporal patterns of magmatism and high-temperature metamorphism in complex subduction systems.…”
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The nonglycosylated variant in therapeutic monoclonal antibodies preferentially forms large aggregates under typical thermal stresses used in forced degradation studies by Gao-Yuan Liu, Jenny Kim Kim, Shuli Tang, Yuetian Yan, Mandi Hopkins, Dalia Laredo, Teng-Chieh Yang, James Mutino, Douglas E. Kamen, Kenneth S. Graham, Mohammed Shameem, Shunhai Wang, Ning Li

“…Monoclonal antibodies (mAbs) feature a conserved N-linked glycosylation site in the CH2 domain, which exhibits heterogeneities in both occupancy and glycan structures. Previous studies have suggested that the unoccupied (nonglycosylated) variant exhibits decreased thermal stability, potentially impacting the overall stability of mAb products. …”
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EAM Integrated Widely Tunable DBR Lasers Based on InGaAlAs/InP MQWs by Mengyang Zhong, Huan Li, Daibing Zhou, Kun Yang, Fei Guo, Dan Lu, Lingjuan Zhao, Song Liang

“…At 25°, the electro-absorption modulator (EAM) of the device has a small signal modulation bandwidth exceeding 27 GHz, which is notably higher than the bandwidth for a TEML device having the same structure but InGaAsP MQW active material. At 25 Gb/s NRZ data modulation, to achieve 10E-10 bit error rate (BER), the power penalty after 5 and 10 km fiber transmission are 1 and 3 dB, respectively. …”
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Temporal variability on Seagrass Cover and Species Composition in a Tourism Hotspot: A case study in Derawan Island by Kusumaningtyas Mariska Astrid, Zulfikar Andi, Rustam Agustin, Salim Hadiwijaya L., Rahayu Yusmiana P., Daulat August, Suryono Devi Dwiyanti, Ati Restu Nur Afi, Sudirman Nasir, Khairunnisa Khairunnisa, Hidayat Wahyu

“…This study aims to assess the resilience of the seagrass ecosystem on Derawan Island by examining temporal variability in seagrass cover and community structure. Permanent plots were established to monitor changes in seagrass cover and community composition. …”
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Mite Domatia and Associated Mite Density in a North American Eastern Deciduous Forest in Michigan by Carolyn D. K. Graham, Lillian R. Bailey, Ashley E. Cole, Anna M. Cress, Emma Dawson‐Glass, Bailee D. Duke, Liam J. Estill, Lauren D. Jones, Gabrielle R. Leon, Samantha Molino, Nia G. Paton, Abrianna J. Soule, Christopher A. Talbot, Addison L. Yerks, Marjorie G. Weber

“…We scored 16 common woody species in a wooded natural area for the presence and number of mite domatia—small structures on the underside of plant leaves that are known to house mutualistic mites. …”
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An innovative thermal simulation study of microstructure improvement by delay forging during solidification by Jiongshen Chen, Li Rong, Chenxi Ma, Wu Wei, Shengping Wen, Kunyuan Gao, Hui Huang, Zuoren Nie

“…Temperature and force data were collected using the Gleeble system for analysis. …”
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Wheat dwarf virus and its impact on the 2020 harvest in some regions of Ukraine by L. Mishchenko, A. Dunich, I. Mishchenko, A. Dashchenko, O. Boyko, O. Skufinskyi, A. Kyrychenko, N. Kozub, T. Mukha

“…Visual diagnostics, enzyme-linked immunosorbent assay in double sandwich modification (DAS-ELISA), polymerase chain reaction, biometric, determination of yield and its structure, statistical data processing. Results. …”
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Magnetic Bifunctional Ru-Enzyme Catalyst Allows for Sustainable Conversion of Cellulose Derivative to D-Sorbitol by Boris B. Tikhonov, Daniil R. Lisichkin, Alexandrina M. Sulman, Alexander I. Sidorov, Alexey V. Bykov, Yury V. Lugovoy, Alexey Y. Karpenkov, Lyudmila M. Bronstein, Valentina G. Matveeva

“…To optimize the nanobiocatalyst structure and composition, we first synthesized the biocatalyst, MNA-CSP-Cel (CSP stands for the CS layer cross-linked by TPP), as well as the nanocatalyst, MNA-CSP-Ru, and studied them in the one-step reactions of hydrolysis and hydrogenation, respectively. …”
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Characterization and kinetic analysis of Vc1509, a NAD+ dependent deacetylase from Vibrio cholerae by Arindam Jana, Pragyan Mishra, Ritu Ghosh, Ajit Kumar Dhal, Shibangini Beura, Amrita Mishra, Rahul Modak

“…Vc1509 is a monomeric protein and harbours conserved secondary structure features of CobB. Our data show that Vc1509 is an active NAD+ dependent lysine de-acylase capable of targeting a broad range of acylated substrates, providing new insights into the enzymatic properties and substrate specificity of CobB bacterial deacetylases.…”
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A hammerhead ribozyme selects mechanically stable conformations for catalysis against viral RNA by Man Lu, Zhiqiang Cao, Luoan Xiong, Hongying Deng, Kangkang Ma, Ning Liu, Yanding Qin, Shen-Bo Chen, Jun-Hu Chen, Yao Li, Yijin Liu, Zhongbo Yu

“…Among them, hammerhead is the smallest and best characterized ribozyme. However, the structure and biochemical data of ribozymes have been disagreed on, making the understanding of its catalysis mechanism a longstanding issue. …”
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Global characterization of mouse testis O-glycoproteome landscape during spermatogenesis by Qiannan Liu, Xiaoyan Lu, Yao Deng, Han Zhang, Rumeng Wei, Hongrui Li, Ying Feng, Juan Wei, Fang Ma, Yan Zhang, Xia Zou

“…Interestingly, we found dynamic changes with an increase Tn and a decrease T structure from early to mature developmental stages. …”
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MtDNA genetic diversity and phylogeographic insights into giant domestic pigeon (Columba livia domestica) breeds: connections between Central Europe and the Middle East by K. Balog, A.S. Wadday, B.A. Al-Hasan, G. Wanjala, Sz. Kusza, P. Fehér, V. Stéger, Z. Bagi

“…The highest genetic diversity was found in the Carpathian Basin, and the lowest in the Iraqi region. STRUCTURE analysis revealed low structurality, K=3 was the most likely. …”
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Psychological correlates of eating behavior in overweight/obese adolescents in Taiwan: Psychometric and correlation analysis of the Three-Factor Eating Questionnaire (TFEQ)-R21 by Yu-Wen Lin, Chung-Ying Lin, Carol Strong, Chih-Hsiang Liu, Yi-Ping Hsieh, Yi-Ching Lin, Meng-Che Tsai

“…This study aimed to assess the factor structure and reliability of TFEQ-R21 and to identify the correlates of eating behavior in obese and non-obese Taiwanese adolescents. …”
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Western disturbances and climate variability: a review of recent developments by K. M. R. Hunt, K. M. R. Hunt, J.-P. Baudouin, A. G. Turner, A. G. Turner, A. P. Dimri, A. P. Dimri, G. Jeelani, Pooja, R. Chattopadhyay, R. Chattopadhyay, F. Cannon, T. Arulalan, T. Arulalan, M. S. Shekhar, T. P. Sabin, E. Palazzi

“…Use of new modelling frameworks and tracking algorithms has significantly improved knowledge of WD structure and variability, and a more frequentist approach can now be taken. …”
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The Automatic Joint Teeth Segmentation in Panoramic Dental Images using Mask Recurrent Convolutional Neural Networks with Residual Feature Extraction: by Raghavendra H. Bhalerao, Abhijeet Ashok Salunke, Shristi Sharan, Kamlesh Kumar, Priyank Rathod, Prince Kumar, Manish Chaturvedi, Nandlal Bharwani, Krupa Shah, Dhruv Patel, Keval Patel, Vikas Warikoo, Manisha Abhijeet Salunke, Shashank Pandya

“…Introduction Panoramic dental images gives an in-depth understanding of the tooth structure, both lower and upper jaws, and surrounding structures throughout the cavity in our mouth.The Panoramic dental images provided have significance for dental diagnostics since they aid in the detection of an array of dental disorders, including oral cancer. …”
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Genetic Differentiation of Abies alba Outside Its Main Range Under Warm Meso‐ and Sub‐Mediterranean Conditions in Italy and Switzerland by Sevil Coşgun, Jérémy Gauthier, Giuliano Bonanomi, Gabriele Carraro, Paolo Cherubini, Marco Conedera, Erika Gobet, Maria‐Chiara Manetti, Gianluigi Mazza, Christoph Schwörer, Christoph Sperisen, Nadir Alvarez, Felix Gugerli, Willy Tinner

“…Collectively, the combined genotypic data from individuals across the species' range demonstrate that cryptic Mediterranean populations of A. alba align with the local and large‐scale genetic structure of populations from its main range, suggesting that the species is able to thrive in a warmer and drier environmental range than hitherto anticipated. …”
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Development and validation of a climate change version of the man-made disaster-related distress scale (CC-MMDS) by Jil Beckord, Julia Barbara Krakowczyk, Nadja Gebhardt, Leonie Sophie Geiser, Katharina Kamler, Christoph Nikendei, Eva-Maria Skoda, Martin Teufel, Alexander Bäuerle

“…Initially, 1070 participants were engaged in the survey. Results: The data of n = 715 participants was used for analysis. …”
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Real-Time FTM-Based Victim Positioning System Using Heterogeneous Robots in Remote and Outdoor Scenarios by Juan Bravo-Arrabal, Carlos Simon Alvarez-Merino, Manuel Toscano-Moreno, Javier Seron-Barba, J. J. Fernandez-Lozano, Jose Antonio Gomez-Ruiz, Emil J. Khatib, Raquel Barco, Alfonso Garcia-Cerezo

“…A centralized Feedback Information System (FIS) processes real-time RTT data from the field, executes a multilateration algorithm, and provides live geolocation updates to SAR coordinators. …”
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Top 10 palliative care research priorities in France: a 3-step, mixed-methods protocol (AXEPRO study) by Stéphane Sanchez, Guillaume Economos, Fiona Ecarnot, Cecile Barbaret, Raphaëlle Habert-Dantigny, Héloïse Rouze, Doan Huynh, Roseline Huynh, Caroline Tête, Martin Julier-Costes, Valérie Amouroux-Gorsse, Isabelle Lavault, Justine Bret

“…A multidisciplinary steering committee including board-certified PC physicians, methodologists, nurses, a sociologist, an anthropologist and an information specialist will analyse the data collected in order to delete duplicate questions, do a thematic and population classification of the responses, modify questions using the PICO (patient problem, intervention, comparison and outcome) format and perform a literature review on each question to identify any relevant systematic review.Ethics and dissemination We expect the results to have wide-ranging benefits, for example, by prompting investment in the 10 prioritised research questions. …”
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Rational selection of the monoclonal α-synuclein antibody amlenetug (Lu AF82422) for the treatment of α-synucleinopathies by Pekka Kallunki, Florence Sotty, Katarina Willén, Michal Lubas, Laurent David, Malene Ambjørn, Ann-Louise Bergström, Louise Buur, Ibrahim Malik, Steffen Nyegaard, Thomas Thiilmark Eriksen, Berit O. Krogh, Jeffrey B. Stavenhagen, Kathrine J. Andersen, Lars Ø. Pedersen, Ersoy Cholak, Edward N. van den Brink, Rik Rademaker, Tom Vink, David Satijn, Paul W.H.I. Parren, Søren Christensen, Line R. Olsen, Josefine N. Søderberg, Sandra Vergo, Allan Jensen, Jan Egebjerg, Pernille Gry Wulff-Larsen, Mikkel N. Harndahl, Dina S. M. Damlund, Kaare Bjerregaard-Andersen, Karina Fog

“…The epitope of amlenetug was mapped to amino acids 112-117 and further characterized by crystallographic structure analysis. Based on our data, we hypothesize that targeting α-synuclein will potentially slow further disease progression by inhibiting further pathology development but be without impact on established pathology and symptoms.…”
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