Association of cancer and outcomes of patients hospitalized for COVID-19 between 2020 and 2023 [version 2; peer review: 1 approved, 2 approved with reservations, 1 not approved] by Robert F Terry, Rugiatu Z Kamara, Robert J Samuels, Donald S Grant, Sulaiman Lakoh, Mustapha Kabba, Innocent Nuwagira, Yusuf Sheku Tejan, Sia Morenike Tengbe, Ibrahim Franklyn Kamara, Shermarke Hassan, Abdulai Tejan Jalloh, Divya Nair, Laura Merson

“…Methods We conducted an analysis on data collected in a large prospective cohort study set-up by the International Severe Acute Respiratory and Emerging Infection Consortium (ISARIC). …”
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Two new species of Ascomycota on bamboo leaves in Fujian, China by Xiayu Guan, Zhiying Zhao, Nemat O. Keyhani, Taichang Mu, Minhai Zheng, Lixia Yang, Yuchen Mao, Junya Shang, Jiao Yang, Huili Pu, Yongsheng Lin, Mengjia Zhu, Huajun Lv, Zhiang Heng, Huiling Liang, Longfei Fan, Xiaoli Ma, Haixia Ma, Zhenxing Qiu, Junzhi Qiu

“…In addition, the morphological characteristics of fungal structures as well as growth parameters were characterized.ResultsWe report two new fungal species, one each within the Didymosphaeriaceae and Magnaporthaceae, both diverse genera that include saprophytes, endophytes, and pathogens. …”
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Using Natural Language Processing to Explore Patient Perspectives on AI Avatars in Support Materials for Patients With Breast Cancer: Survey Study by Eleanor Cheese, Raouef Ahmed Bichoo, Kartikae Grover, Dorin Dumitru, Alexandros Zenonos, Joanne Groark, Douglas Gibson, Rebecca Pope

“…We applied and evaluated different NLP machine learning techniques to draw insights from these unstructured data, namely sentiment analysis, topic modeling, summarization, and term frequency–inverse document frequency word clouds. …”
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Development and Application of a Senolytic Predictor for Discovery of Novel Senolytic Compounds and Herbs by Jinjun Li, Kai Zhao, Guotai Yang, Haohao Lv, Renxin Zhang, Shuhan Li, Zhiyuan Chen, Min Xu, Naixue Yang, Shaoxing Dai

“…In the DrugBank database, 98 structurally novel candidate compounds with potential senolytic activity were identified. …”
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Human lung cancer neutrophils generate NETs with preserved anti-tumor cytotoxicity but impaired anti-migratory activity by Nuha Alsharif, Nuha Alsharif, Mohamad Qaisi, Merav Shaul, Naomi Kaisar-Iluz, Naomi Kaisar-Iluz, Dan Padawer, Dan Padawer, Osnath Bouhanna, Osnath Bouhanna, Yael Volman, Yael Volman, Zvi G. Fridlender, Zvi G. Fridlender

“…Neutrophil extracellular traps (NETs) are DNA-protein structures released during a form of programmed neutrophil death known as NETosis. …”
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The evolution of sprinting performance: Technological and regulatory influences from 1976 to 2024 by Dariusz Tadeusz SKALSKI, Magdalena PROŃCZUK, Kinga ŁOSIŃSKA, Ewelina LULIŃSKA, Joanna MOTOWIDŁO, Petr STASTNY, Adam MASZCZYK, Grzegorz TRYBEK

“…Additionally, the study highlights the narrowing gender performance gap, driven by advancements in sports science, improved access to elite training, and evolving competition structures. Conclusions: Regulatory measures, particularly in anti-doping enforcement, have played a crucial role in preserving fair competition and influencing performance trends. …”
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Operational considerations for approximating molecular assembly by Fourier transform mass spectrometry by Gabriella M. Weiss, Gabriella M. Weiss, Gabriella M. Weiss, Silke Asche, Hannah McLain, Angela H. Chung, Angela H. Chung, Angela H. Chung, S. Hessam M. Mehr, Leroy Cronin, Heather V. Graham

“…Because AT makes no assumptions about the chemistry of life, it is an agnostic tool that identifies molecular structures that are probabilistically more likely to have arisen via selection and therefore biological processes. …”
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Anti-HIV-1 Effect of the Fluoroquinolone Enoxacin and Modulation of Pro-Viral hsa-miR-132 Processing in CEM-SS Cells by Verena Schlösser, Helen Louise Lightfoot, Christine Leemann, Seyedeh Elnaz Banijamali, Aathma Merin Bejoy, Shashank Tiwari, Jeffrey L. Schloßhauer, Valentina Vongrad, Andreas Brunschweiger, Jonathan Hall, Karin J. Metzner, Jochen Imig

“…Results: We established that Enoxacin, but not the structurally similar compound nalidixic acid, exhibits strong anti-HIV-1 effects in the T-cell line CEM-SS, but not MT-4. …”
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O-prenylchalcones inhibit cell proliferation and activate apoptosis by inducing mitochondrial dysfunction in gastric cancer cells by José C. Espinoza-Hicks, Yarely M. Salinas-Vera, Javier Camarillo-Cisneros, Alejandro A. Camacho-Dávila, Jessica L. Hernández-Rivera, Nadia Flores-Huerta, Eloisa Ibarra-Sierra, Carlos Pérez-Plasencia, María Elizbeth Álvarez-Sánchez, Ángeles C. Tecalco-Cruz, César López-Camarillo

“…The interactions between the O-prenylchalcones and selected oncoproteins were predicted by first identifying the most stable conformers, and approximately 5,000 structures were evaluated by force field molecular dynamics. …”
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Augmented Reality Navigation in Craniomaxillofacial/Head and Neck Surgery by E. Brandon Strong, Anuj Patel, Alexander P. Marston, Cameron Sadegh, Jeffrey Potts, Darin Johnston, David Ahn, Shae Bryant, Michael Li, Osama Raslan, Steven A. Lucero, Marc J. Fischer, Marike Zwienenberg, Neha Sharma, Florian Thieringer, Christian El Amm, Kiarash Shahlaie, Marc Metzger, E. Bradley Strong

“…Virtual surgical plans were generated from computed tomography/magnetic resonance imaging data and uploaded onto the AR platform. A reference array was mounted to the patient, and the virtual plan was registered to the patient intraoperatively. …”
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The Robust Detection and Spatial Distribution of Acetaldehyde in Orion KL: Atacama Large Millimeter/submillimeter Array Observations and Chemical Modeling by Miwha Jin, Anthony J. Remijan, Robin T. Garrod, Giseon Baek, Martin Cordiner, Steven Charnley, Eric Herbst, Jeong-Eun Lee

“…We analyze extensive Atacama Large Millimeter/submillimeter Array archival data sets (142–355 GHz) to search for acetaldehyde, revealing two distinct acetaldehyde emission peaks and one component with more complex kinematic structures. …”
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Systematic evaluation of single-cell RNA-seq analyses performance based on long-read sequencing platforms by Enze Deng, Qingmei Shen, Jingna Zhang, Yaowei Fang, Lei Chang, Guanzheng Luo, Xiaoying Fan

“…However, the NGS-based scRNA-seq only quantifies gene expression and cannot reveal the exact transcript structures (isoforms) of each gene due to the limited read length. …”
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Recovery and study of human remains at the Chapel of S. Domenico – Al-Tahira Cathedral of the Syro-Catholic Archdiocese of Mosul located in Quaraqosh, Iraq: Medico-legal and foren... by Laura Donato, Douglas H Ubelaker, Rossana Cecchi, Jessika Camatti, Marco Albore, Gianpiero D'Antonio, Gabriele Napoletano, Letizia Sorace, Michele Treglia, Luigi Tonino Marsella, Costantino Ciallella

“…C2 showed a cranial disintegration with fracture fragments affecting the structures of the left neuro- and splanchnic skull and to a greater extent the left hemifacial, orbital, zygomatic regions and thethe same side of the face. …”
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Theoretical–Cheminformatic Study of Four Indolylphytoquinones, Prospective Anticancer Candidates by Edgar Daniel Moyers-Montoya, María Jazmín Castañeda-Muñoz, Daniel Márquez-Olivas, René Miranda-Ruvalcaba, Carlos Alberto Martínez-Pérez, Perla E. García-Casillas, Wilber Montejo-López, María Inés Nicolás-Vázquez, René Gerardo Escobedo-González

“…Results: The results revealed that the studied structures possibly presented antineoplastic activity, in addition to the fact that the reactivity parameters showed that two of the evaluated compounds have the option to present IC₅₀ values lower than or similar to 25 mg/mL, activity like that of indolylisoperezone; moreover, they show molecular coupling to PARP-1. …”
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UE-NER-2025: A GPT-Based Approach to Multi-Lingual Named Entity Recognition on Urdu and English by Muhammad Ahmad, Humaira Farid, Iqra Ameer, Fida Ullah, Muhammad Muzamil, Muhammad Jalal, Ameer Hamza, Ildar Batyrshin, Grigori Sidorov

“…Named Entity Recognition (NER) is a fundamental task that identifies and classifies entities into predefined categories from unstructured text. As textual data continues to grow and span diverse linguistic communities, NER is rarely studied as a multilingual task, particularly for low-resource languages. …”
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Multicenter study correlating molecular characteristics and clinical outcomes of cancer cases with patient-derived organoids by Paloma Navarro, Tatiana P. Grazioso, Arantzazu Barquín, Maria Barba, Mónica Yagüe, Carlos Millán, Irene López, Elena Sevillano, Miguel Quiralte, Paloma Fernández, Diego Losada, Eduardo Caleiras, Julia Calzas, Beatriz Jiménez, Sergio Ruiz-Llorente, Juan Justo, Félix Guerrero, Vital Hevia, Raquel Martín, Francisco José Pérez-Rodriguez, Julia Tejerina, Mario Prieto, Paula Comune, Juan Francisco Rodriguez-Moreno, Jesús García-Donás

“…Abstract Background 3D-spatial interaction between cancer cells influences tumor behavior, making it essential to replicate tumor structures for predicting patient outcomes. Methods We collected data from three multicenter prospective studies to evaluate the ability to establish Patient-Derived Organoids (PDOs) from different biological samples and timepoints, correlating their characteristics and drug sensitivity with clinical outcomes. …”
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Newly diagnosed diseases and the frequency of their occurrence in patients after a new coronavirus infection. Results of an International Register "Dynamics Analysis of Comorbiditi... by G. P. Arutyunov, E. I. Tarlovskaya, A. G. Arutyunov, D. S. Polyakov, Yu. N. Belenkov, A. O. Konradi, Yu. M. Lopatin, A. P. Rebrov, S. N. Tereshchenko, A. I. Chesnikova, H. G. Hayrapetyan, A. P. Babin, I. G. Bakulin, N. V. Bakulina, L. A. Balykova, A. S. Blagonravova, M. V. Boldina, M. I. Butomo, A. R. Vaisberg, A. S. Galyavich, V. V. Gomonova, N. Yu. Grigoryeva, I. V. Gubareva, I. V. Demko, A. V. Evzerikhina, A. V. Zharkov, A. A. Zateishchikova, U. K. Kamilova, Z. F. Kim, T. Yu. Kuznetsova, A. N. Kulikov, N. V. Lareva, E. V. Makarova, S. V. Malchikova, S. V. Nedogoda, M. M. Petrova, I. G. Pochinka, K. V. Protasov, D. N. Protsenko, D. Yu. Ruzanov, S. A. Saiganov, A. Sh. Sarybaev, N. M. Selezneva, A. B. Sugraliev, I. V. Fomin, O. V. Khlynova, O. Yu. Chizhova, I. I. Shaposhnik, D. A. Schukarev, A. K. Abdrakhmanova, S. A. Avetisyan, H. G. Avoyan, K. K. Azaryan, G. T. Aimakhanova, D. A. Ayypova, A. Ch. Akunov, M. K. Alieva, A. R. Almukhambedova, O. Yu. Aparkina, O. R. Aruslanova, E. Yu. Ashina, O. Yu. Badina, O. Yu. Barysheva, T. I. Batluk, A. S. Batchaeva, R. A. Bashkinov, A. M. Bitieva, I. U. Bikhteev, N. A. Borodulina, M. V. Bragin, V. A. Brazhnik, A. M. Budu, G. A. Bykova, K. R. Vagapova, D. D. Varlamova, N. N. Vezikova, E. A. Verbitskaya, O. E. Vilkova, E. .A. Vinnikova, V. V. Vustina, E. A. Elena A. Galova, V. V. Genkel, D. B. Giller, E. D. Gordeychuk, E. I. Gorshenina, E. V. Grigoryeva, E. Yu. Gubareva, G. M. Dabylova, A. I. Demchenko, O. Yu. Dolgikh, M. Y. Duishobaev, D. S. Evdokimov, K. E. Egorova48, A. E. Zheldybaeva, N. V. Zarechnova, Yu. D. Zimina, S. Yu. Ivanova, E. Yu. Ivanchenko, M. V. Ilina, M. V. Kazakovtseva, E. V. Kazymova, Yu. S. Yuliya S. Kalinina, N. A. Kamardina, A. M. Karachenova, I. A. Karetnikov, N. A. Karoli, M. Kh. Karsiev, D. S. Kaskaeva, K. F. Kasymova, Zh. B. Kerimbekova, E. S. Kim, N. V. Kiseleva, D. A. Klimenko, O. V. Kovalishena, S. V. Kozlov, E. V. Kolmakova, T. P. Kolchinskaya, M. I. Kolyadich, O. V. Kondryakova, M. P. Konoval, D. Yu. Konstantinov, E. A. Konstantinova, V. A. Kordyukova, E. V. Koroleva, A. Yu. Kraposhina, T. V. Kryukova, A. S. Kuznetsova, T. Yu. Kuzmina, K. V. Kuzmichev, C. K. Kulchoroeva, T. V. Kuprina, I. M. Kuranova, L. V. Kurenkova, N. Yu. Kurchugina, N. A. Kushubakova, V. I. Levankova, A. A. Ledyaeva, T. V. Lisun, V. E. Lisyanskaya, N. A. Lyubavina, N. A. Magdeeva, K. V. Mazalov, V. I. Mayseenko, A. S. Makarova, A. M. Maripov, N. V. Markov, A. A. Marusina, E. S. Melnikov, A. I. Metlinskaya, N. B. Moiseenko, F. N. Muradova, R. G. Muradyan, Sh. N. Musaelyan, E. S. Nekaeva, N. M. Nikitina, S. E. Nifontov, E. Yu. Obolentseva, A. A. Obukhova, B. B. Ogurlieva, A. A. Odegova, Yu. V. Yuliya V. Omarova, N. A. Omurzakova, Sh. O. Ospanova, V. A/ Pavlova, E. V. Pakhomova, L. D. Petrov, S. S. Plastinina, D. A. Platonov, V. A. Pogrebetskaya, D. V. Polyakov, E. V. Ponomarenko, L. L. Popova, A. A. Potanin, N. A. Prokofieva, Yu. D. Rabik, N. A. Rakov, A. N. Rakhimov, N. A. Rozanova, S. Serikbolkyzy, Ya. A. Sidorkina, A. A. Simonov, V. V. Skachkova, R. D. Skvortsova, D. S. Skuridin, D. V. Solovieva, I. A. Solovieva, I. M. Sukhomlinova, A. G. Sushilova, D. R. Tagaeva, E. P. Tikhonova, D. S. Tokmin, A. A. Tolmacheva, M. S. Torgunakova, K. V. Trenogina, N. A. Trostyanetskaya, D. A. Trofimov, M. A. Trubnikova, A. A. Tulichev, A. T. Tursunova, N. D. Ulanova, O. V. Fatenkov, O. V. Fedorishina, T. S. Fil, I. Yu. Fomina, I. S. Fominova, I. A. Frolova, S. M. Tsvinger, V. V. Tsoma, M. B. Cholponbaeva, T. I. Chudinovskikh, I. V. Shavrin, O. A. Shevchenko, D. R. Shikhaliev, E. A. Shishkina, K. Yu. Shishkov, S. Yu Shcherbakov, G. V. Shcherbakova, E. A. Yausheva

“…Demographic, clinical, and laboratory data, computed tomography (CT) results, information about inhospital clinical course and complications of COVID-19 during hospitalization were extracted from electronic health records using a standardized data collection form. …”
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Engagement of Indigenous peoples in commercial tobacco reform strategies: a scoping review protocol by Andrew Waa, Raglan Maddox, El-Shadan Tautolo, Michelle Kennedy, Patricia Nez Henderson, Hershel Clark, Priscilla Nez, Penney Upton, Andrew Daniel Perusco, Sydney A. Martinez, Sierra Wilcox, Jeyasakthi Venugopal

“…This review supports the global goal of eradicating commercial tobacco-related harms – reframing commercial tobacco use as a structurally imposed harm sustained by colonial and commercial forces rather than personal choice. …”
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White matter and cortical gray matter microstructural alterations in migraine: a NODDI and DTI analysis by Zhilei Li, Yanliang Mei, Lei Wang, Tianhua Fan, Cheng Peng, Kaibo Zhang, Shouyi Wu, Tong Chen, Zhenchang Zhang, Binbin Sui, Yonggang Wang, Xueying Yu

“…The plasticity changes in neuronal structures and neurotransmitter system dysregulations potentially play a crucial role in migraine onset and chronicity of migraine. …”
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Desulfovibrio vulgaris flagellin exacerbates colorectal cancer through activating LRRC19/TRAF6/TAK1 pathway by Yue Dong, Fanyi Meng, Jingyi Wang, Jingge Wei, Kexin Zhang, Siqi Qin, Mengfan Li, Fucheng Wang, Bangmao Wang, Tianyu Liu, Weilong Zhong, Hailong Cao

“…Flagella are important accessory structures of bacteria, which can help them colonize and enhance their invasive ability. …”
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