Seroprevalence of anti-SARS-CoV-2 antibodies and risk of viral exposure among healthcare workers in the South Kivu province, eastern Democratic Republic of the Congo: a cross-secti... by Denis Mukwege, Andreas Kalk, Tim Eckmanns, Andreas Nitsche, Fabian H Leendertz, Tshass B Chasinga, Jean-Paul Buhendwa Cikwanine, Sarah Kribi, Jonathan Tunangoya Yoyu, Natalie Hofmann, Marica Grossegesse, Sara Tomczyk, Ann C Vietor, Aline B Kusinza, Eric Munguakonkwa, Maroyi Raha, Nelson S Kambale, Rodrigue B Ayagirwe, Grit Schubert

“…The present study aims to measure the impact of SARS-CoV-2 on HCWs in central sub-Saharan Africa.Setting A cross-sectional serological study was conducted at six urban and five rural hospitals during the first pandemic wave in the South Kivu province, Democratic Republic of the Congo (DRC).Participants Serum specimens from 1029 HCWs employed during the first pandemic wave were collected between August and October 2020, and data on demographics and work-related factors were recorded during structured interviews.Primary and secondary outcome measures The presence of IgG antibodies against SARS-CoV-2 was examined by ELISA. …”
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Complementary medicine among individuals experiencing homelessness in Switzerland: a quantitative and qualitative descriptive study by Véronique S. Grazioli, Evelyne Hangartner, Patrick Bodenmann, Luana Schaad, Léa Grosjean, Justin Nikles, David J. T. Campbell, Laurent Hyvert, Tshahé Anongba Varela, Susan E. Collins, Caroline Leblanc, Christine Loignon, Chantal Berna

“…A subsample of the survey participants (n = 18) and 14 professionals working in the homeless-serving sector participated in semi-structured interviews exploring perceived utility of CM for PEH. …”
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Risk Factors, Clinical Characteristics, and Antibiotic Susceptibility Patterns of <i>Streptococcal</i> Keratitis: An 18-Year Retrospective Study from a Tertiary Hospital in China by Zhen Cheng, Qingquan Shi, Bo Peng, Zijun Zhang, Zhenyu Wei, Zhiqun Wang, Yang Zhang, Kexin Chen, Xizhan Xu, Xinxin Lu, Qingfeng Liang

“…IVCM revealed deeper inflammatory cell distribution and structural disruption as the disease progressed. Resistance rates of aminoglycosides, β-lactams, and fluoroquinolones have increased, with significant differences among species for amikacin (<i>p</i> = 0.010), gentamicin (<i>p</i> = 0.007), and others. …”
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Clinical genome sequencing in patients with hereditary breast and ovarian cancer: Concept, implementation and benefits by Dennis Witt, Marc Sturm, Antje Stäbler, Benita Menden, Lisa Ruisinger, Kristin Bosse, Ines Gruber, Andreas Hartkopf, Silja Gauß, German Demidov, Nicolas Casadei, Elena Buena Atienza, Kira Mehnert, Janna Witt, Caspar Gross, Leon Schütz, Christopher Schroeder, Stephan Ossowski, Andreas Dufke, Tobias B. Haack, Olaf Riess, Ulrike Faust

“…GS offers a wealth of information, including the improved detection of structural variants, copy number variants, and parallel detection of complex genetic markers. …”
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The antioxidant property of CAPE depends on TRPV1 channel activation in microvascular endothelial cells by Miltha Hidalgo, Bárbara Railef, Vania Rodríguez, Carolina Navarro, Vanessa Rubio, Jorge Meneses-Pacheco, Sandra Soto-Alarcón, Christine Kreindl, Carolina Añazco, Leandro Zuñiga, Omar Porras

“…Herein, we hypothesized that a subfamily of TRP ion channels works as the molecular entity that recognizes CAPE at the plasma membrane and allows a fast shift in the antioxidant capacity of intact endothelial cells (EC).By monitoring cytoplasmic Ca2+ in a microvascular EC model, we compared the calcium responses evoked by three structurally related compounds: caffeic acid phenethyl ester, neochlorogenic acid and caffeic acid. …”
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MERS-CoV seroconversion amongst Malaysian Hajj pilgrims returning from the Middle East, 2016–2018: results from the MERCURIAL multiyear prospective cohort study by Jefree Johari, Robert D. Hontz, Brian L. Pike, Tupur Husain, Norhayati Rusli, Rozainanee Mohd-Zain, Vunjia Tiong, Hai-Yen Lee, Boon-Teong Teoh, Sing-Sin Sam, Chee-Sieng Khor, Shih-Keng Loong, Juraina Abd-Jamil, Siti-Sarah Nor'e, Hasmawati Yahaya, Naim Che-Kamaruddin, Jose A. Garcia-Rivera, Sazaly AbuBakar

“…ELISAs and micro-neutralization assays were performed to detect the presence of MERS-CoV IgG antibodies. Sociodemographic data, symptoms experienced during Hajj, and history of exposure to camels or camel products were recorded using structured pre- and post-Hajj questionnaires. …”
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Traditional uses and importance of Strychnos L. (Loganiaceae): A cross-cultural and spatial variation study in Benin by Donald Djidohokpin, Gbèwonmèdéa Hospice Dassou, Gnimansou Abraham Favi, Octave Mathieu Zountangni, Jéronime Marie-Ange Sènami Ouachinou, Judicael Makponsè, Ghyslain Kpetikou, Gbèkponhami Monique Tossou, Hounnankpon Yédomonhan, Aristide Cossi Adomou

“…Detailed information about uses and homemade herbal remedies regarding the medicinal category was collected. Data were analyzed through the citation frequencies and homemade remedy report (HR) using Excel. …”
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Optical genome mapping: Unraveling complex variations and enabling precise diagnosis in dystrophinopathy by Jiahui Mai, Jing Duan, Xiaoyu Chen, Liqin Liu, Dachao Liang, Tao Fu, Gang Lu, Wai Yee Chan, Xufeng Luo, Feiqiu Wen, Jianxiang Liao, Zhuo Li, Xinguo Lu

“…We used the optical genome mapping (OGM) technology to detect and analyze uncommon mutations or structural variations (SVs) within the DMD gene, thus contributing to more precise clinical diagnoses. …”
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Audio and linguistic prediction of objective and subjective cognition in older adults: what is the role of different prompts? by Varsha D. Badal, Varsha D. Badal, Caitlyn Tran, Haze Brown, Danielle K. Glorioso, Danielle K. Glorioso, Rebecca Daly, Rebecca Daly, Anthony J. A. Molina, Anthony J. A. Molina, Alison A. Moore, Alison A. Moore, Erhan Bilal, Ellen E. Lee, Ellen E. Lee, Ellen E. Lee, Colin A. Depp, Colin A. Depp, Colin A. Depp

“…BackgroundPsycho-linguistic and audio data derived from speech may be useful in screening and monitoring cognitive aging. …”
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Assessment of usage, reuse and disposal of thermoplastic masks among radiotherapy technologists in India: A nationwide perspective by M. Nagesh, Rohit Vadgaonkar, K.K. Sreelakshmi, Raghavendra Hajare, Pritam Parab, Subhabrat Dash, Ramesh Reddy, Vaishali Shende, Ankita Nawar, Rahul Biswas, Sandeep Ratna Bula, Shubham Gagare, Darshani Belekar, Raviteja Miriyala, Umesh Mahantshetty

“…Materials and Methods: A cross-sectional survey was conducted among RTTs working in different healthcare settings. A structured questionnaire designed by a team of RTTs and radiation oncologists was used to collect responses. …”
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CTV-MIND: A cortical thickness-volume integrated individualized morphological network model to explore disease progression in temporal lobe epilepsy by Xinyan Liu, Jiaqi Han, Xiating Zhang, Boxuan Wei, Lu Xu, Qilin Zhou, Yuping Wang, Yicong Lin, Jicong Zhang

“…This study aimed to investigate progressive changes in TLE by constructing a novel individualized morphological brain network based on T1-weighted structural magnetic resonance imaging (MRI). MRI data were collected from 34 postoperative seizure-free TLE patients and 28 age- and sex-matched healthy controls (HC), with patients divided into LONG-TERM and SHORT-TERM groups. …”
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Prevalence and risk factors of Helicobacter pylori infection in urban children aged 6–13 years in Fuzhou, China: a cross-sectional study in a high gastric cancer incidence region by Youtao Chen, Youtao Chen, Youtao Chen, Xiaoting Pan, Xiaoting Pan, Xiaoting Pan, Yanyan Wang, Yanyan Wang, Longzhen Lin, Xiaoyan Chen, Xiaoyan Chen, Yan Chen, Yan Chen, Hong Ye, Hong Ye, Hong Ye

“…BackgroundThe burden of Helicobacter pylori infection remains a global public health concern, particularly due to its lifelong risk of gastric cancer starting from childhood. Comprehensive data on the prevalence of H. pylori infection and associated risk factors among children are limited. …”
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Safety of mycophenolate mofetil in systemic lupus erythematosus maintenance therapy: insights from the LUNA registry in a nationwide prospective cohort study by Ken-ei Sada, Shuhei Yoshida, Kenji Saito, Yuya Fujita, Eisuke Inoue, Kiyoshi Migita, Naoki Matsuoka, Hiroshi Kajiyama, Ryusuke Yoshimi, Kunihiro Ichinose, Yoshia Miyawaki, Shigeru Ohno, Nobuyuki Yajima, Yasuhiro Shimojima, Shuzo Sato, Michio Fujiwara, Keisuke Nishimura, Takashi Kida, Yuya Sumichika, Haruki Matsumoto, Jumpei Temmoku, Tomoyuki Asano, Shotaro Ogawa, Jumpei Fukita, Yusuke Matsuo, Takahisa Onishi

“…Statistical analyses employed marginal structural models with stabilised inverse probability of treatment weighting to adjust for confounders.Results The analysis included 1004 patients; the incidence of severe infections was 6.5% in the MMF group and 7.5% in the non-MMF group, with no significant difference (OR 0.69, 95% CI 0.34 to 1.39). …”
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Bringing a Systems Approach to Living Donor Kidney Transplantation by Anna Horton, Katya Loban, Peter Nugus, Marie-Chantal Fortin, Lakshman Gunaratnam, Greg Knoll, Istvan Mucsi, Prosanto Chaudhury, David Landsberg, Michel R. Pâquet, Marcelo Cantarovich, Shaifali Sandal

“…Findings may be used to guide structured organizational change toward increasing LDKT and mitigating the global burden of kidney failure.…”
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The mediating role of physical activity avoidance in the association between weight stigma and physical activity by Po-Ching Huang, Hung-Ching Wu, Ji-Kang Chen, Xavier C.C. Fung, Nadia Bevan, Daniel Kwasi Ahorsu, Mark D. Griffiths, Jung-Sheng Chen, Kuo-Hsin Lee, Amir H. Pakpour, Chung-Ying Lin

“…Results: Structural equation modeling showed that weight-related self-stigma was significantly associated with PA avoidance (standardized coefficient [β] = 0.67, p < 0.01), and negatively associated with PA (β = −0.14, p < 0.01). …”
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Executive dysfunction relates to salience network desegregation in behavioural variant frontotemporal dementia by Melanie A. Matyi, Hamsanandini Radhakrishnan, Christopher A. Olm, Jeffrey S. Phillips, Philip A. Cook, Emma Rhodes, James C. Gee, David J. Irwin, Corey T. McMillan, Lauren Massimo

“…Given that behavioral variant frontotemporal degeneration (bvFTD) is a neurodegenerative disease associated with executive dysfunction and selective vulnerability of the salience network, we tested the hypotheses that bvFTD structural networks are de-differentiated compared to cognitively normal controls (CNC) and that network de-differentiation relates to worse executive function. …”
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Single-cell chromatin accessibility profiling reveals regulatory mechanisms and evolution in pig brains by Yue Xiang, Saixian Zhang, Yi Huang, Zhuqing Zheng, Jiahui Sun, Qiulin Zhao, Peng Zhou, Xiaolong Qi, Jingjin Li, Fuyang Xiong, Jing Xu, Shengquan Wang, Liangliang Fu, Xinyun Li

“…Abstract Background Pig brains serve as a valuable biomedical model for studying brain-related diseases due to their significant structural similarities to the human brain. Furthermore, the long-term domestication and artificial selection of domestic pigs have profoundly shaped their brains, making them an interesting subject for research. …”
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Exploring the Challenges Faced by Small Insurance Brokers in Achieving Sustainable Growth: A Case Study in Botswana's Insurance Industry by Maalila Malambo

“…Design/methodology/approach: An online questionnaire was distributed to 50 small insurance brokers in Botswana, with a response rate of 70%. Semi-structured interviews were conducted with 10 key stakeholders, including regulators and customers, to gain deeper insights. …”
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Research on the charging periods of the ultra-shallow play in front of the Hashan area, northwestern margin of the Junggar Basin by WANG Qianjun, ZHOU Jian, ZHANG Faqiang, YU Hongzhou, WU Qianqian, LU Hongli, LIU Qingxin, ZHOU Yu, CHENG Ming, YAN Jianzhao, LYU Yanfang

“…The second phase took place during the Late Cretaceous (73 Ma), marked by structural adjustment and hydrocarbon redistribution. …”
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Predictors and health impacts of Ramadan intermittent fasting among patients with sickle cell disease by Mortadah Hadi Alsalman, Zaenb Alsalman, Maryam Mohammed Alshams, Jinan Mohammed Aljasem, Zahra Saleh Alsindi, Amani Abdullah Almutairi, Khadija Abdulrahman Alsunaikh, Hadeel Hesham Buali, Kefah Baqir Algadeeb, Nawal Eltayeb Omer Mohammed, Abdulaziz Abdullah Bushehab, Marwa Mahmoud Shafey

“…This study seeks to identify predictors of fasting capability and investigate the effects of fasting among this patient population.Participants and methodsThis cross-sectional study enrolled adult Muslim patients with SCD from Saudi Arabia. Data were collected through direct interviews using a structured questionnaire with four sections.ResultsA total of 320 patients with SCD were evaluated, with a mean age of 32.6 years (SD ± 11.01) and the majority were females (63.1%). …”
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