Exploring cognitive and neuroimaging profiles of dementia subtypes of individuals with dementia in the Democratic Republic of Congo by Jean Ikanga, Jean Ikanga, Saranya Sundaram Patel, Saranya Sundaram Patel, Megan Schwinne, Caterina Obenauf, Caterina Obenauf, Emmanuel Epenge, Guy Gikelekele, Nathan Tshengele, Immaculee Kavugho, Samuel Mampunza, Lelo Mananga, Charlotte E. Teunissen, Julio C. Rojas, Brandon Chan, Argentina Lario Lago, Joel H. Kramer, Adam L. Boxer, Andreas Jeromin, Emile Omba, Alvaro Alonso, Alden L. Gross

“…Core AD biomarkers (Aβ42/40 and p-tau181) and non-specific neurodegeneration biomarkers (NfL, GFAP) were measured in blood plasma. Neuroimaging structures were assessed using magnetic resonance imaging (MRI). …”
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Systemic inflammation is an important risk factor and predictor of graft loss and mortality one year after kidney transplantation by Torbjørn F. Heldal, Torbjørn F. Heldal, Torbjørn F. Heldal, Anders Åsberg, Anders Åsberg, Anders Åsberg, Thor Ueland, Thor Ueland, Thor Ueland, Anna V. Reisæter, Anna V. Reisæter, Søren E. Pischke, Søren E. Pischke, Tom E. Mollnes, Tom E. Mollnes, Pål Aukrust, Pål Aukrust, Pål Aukrust, Pål Aukrust, Finn P. Reinholt, Anders Hartmann, Anders Hartmann, Kristian Heldal, Kristian Heldal, Kristian Heldal, Trond G. Jenssen, Trond G. Jenssen

“…BackgroundAn inflammatory environment following kidney transplantation is associated with increased risk of graft loss and mortality, however, evaluation of systemic inflammation is not implemented in structured risk assessment in kidney transplant recipients. …”
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Postnatal care could be the key to improving the continuum of care in maternal and child health in Ratanakiri, Cambodia. by Kimiyo Kikuchi, Junko Yasuoka, Keiko Nanishi, Ashir Ahmed, Yasunobu Nohara, Mariko Nishikitani, Fumihiko Yokota, Tetsuya Mizutani, Naoki Nakashima

“…Overall, 377 women were included, and data were collected via face-to-face interviews using a semi-structured questionnaire. …”
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Sources of uncertainty in DNA metabarcoding of whole communities: Implications for its use in biomonitoring by J. Iwan Jones, Amanda Arnold, Dominik Buchner, John F. Murphy, Jasmine N. Childress, Pedro Beja, Florian Altermatt, Kristian Meissner, Ian Adams, Meri Anderson, Yaisel J. Borrell, Andrew G. Briscoe, Kat Bruce, Cátia Chaves, Chris Conyers, Kristy Deiner, Vasco Elbrecht, Álvaro Fueyo, Tim Goodall, Javier Granero‐Castro, Cristina Hartmann‐Fatu, Eleanor Jones, Elvira Mächler, Filipa M. S. Martins, Sam McGreig, Lyndall Pereira‐da‐Conceicoa, James L. Pretty, Daniel S. Read, Ben Price, Florian Leese, Rosetta C. Blackman

“…However, the routine application of DNA‐based methods to monitor whole communities using a metabarcoding approach and derive ecosystem status continues to be limited. We undertook a structured experiment to assess factors influencing the precision and accuracy of molecular methods for freshwater macroinvertebrate community assessment. …”
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Predicting coronavirus disease 2019 severity using explainable artificial intelligence techniques by Takuya Ozawa, Shotaro Chubachi, Ho Namkoong, Shota Nemoto, Ryo Ikegami, Takanori Asakura, Hiromu Tanaka, Ho Lee, Takahiro Fukushima, Shuhei Azekawa, Shiro Otake, Kensuke Nakagawara, Mayuko Watase, Katsunori Masaki, Hirofumi Kamata, Norihiro Harada, Tetsuya Ueda, Soichiro Ueda, Takashi Ishiguro, Ken Arimura, Fukuki Saito, Takashi Yoshiyama, Yasushi Nakano, Yoshikazu Muto, Yusuke Suzuki, Ryuya Edahiro, Koji Murakami, Yasunori Sato, Yukinori Okada, Ryuji Koike, Makoto Ishii, Naoki Hasegawa, Yuko Kitagawa, Katsushi Tokunaga, Akinori Kimura, Satoru Miyano, Seishi Ogawa, Takanori Kanai, Koichi Fukunaga, Seiya Imoto

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OrchidBase 6.0: increasing the number of Cymbidium (Orchidaceae) genomes and new bioinformatic tools for orchid genome analysis by You-Yi Chen, Ye Sun, Chung-I Li, Shao-Ting Lin, Hao-Chen Zheng, Zhe-Bin Zhang, Bing-Ru Lee, Chun-Lin Hsieh, Yu-Yun Hsiao, Chi-Nga Chow, Chien-Wen Yang, Wen-Chi Chang, Heming Chen, Feng-Xi Yang, Gen-Fa Zhu, Qinyao Zheng, Cheng-Yuan Zhou, Zhuang Zhao, Ye Ai, Lin-Ying Wang, Deqiang Chen, Xin He, Ming-Zhong Huang, Dong-Hui Peng, Hao Yu, Siren Lan, Zhong-Jian Liu, Wei-Sheng Wu, Wen-Chieh Tsai

“…Abstract Background Orchids are well-known for their rich diversity of species as well as wide range habitats. Their floral structures are so unique in angiosperms that many of orchids are economically and culturally important in human society. …”
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Sixty Degrees of Solutions: Field Techniques for Human–Jaguar Coexistence by John Polisar, Rafael Hoogesteijn, Almira Hoogesteijn, Diego Francis Passos Viana, Skarleth Johana Chinchilla Valdiviezo, Carlos Valderrama Vásquez, Allison Loretta Devlin, Ranni José Arias Herrera, Margaux Babola, Frederick Bauer, Ivonne Cassaigne Guasco, Chia Yu Chang, Daniel Corrales Gutiérrez, J. Antonio De la Torre, Wezddy Del Toro-Orozco, Aline Kotz, Duston Larsen, Nicolás Lodeiro Ocampo, Daniel Monzón, Carmen Angélica Morante Ascanio, Ricardo Daniel Ortiz-Hoyos, Pablo Gastón Perovic, Grasiela Edith de Oliviero Porfirio, María Fernanda Puerto Carrillo, Paul Raad, Thiago Reginato, Yina Paola Serna, Claudio Sillero-Zubiri, Laura Villalba, Armand Ziller

“…Throughout this geographical breadth, jaguars represent an essential component of native biological diversity, but conflict revolving around real and perceived jaguar depredation on livestock is a factor in jaguar mortality. We developed a structured questionnaire to evaluate the effectiveness of anti-depredation strategies from northern Mexico to Argentina, collecting data from 11 countries and 248 livestock operations, 194 with efficacy metrics, and 24 with benefit–cost ratios (value of the livestock losses averted/cost of the intervention). …”
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‘A good decision is the one that feels right for me’: Codesign with patients to inform theoretical underpinning of a decision aid website by Kelly Kohut, Kate Morton, Karen Hurley, Lesley Turner, The CanGene‐CanVar Patient Reference Panel, Caroline Dale, Susan Eastbrook, Rochelle Gold, Kate Henwood, Sonia Patton, Reshma Punjabi, Helen White, Charlene Young, Julie Young, Elizabeth Bancroft, Lily Barnett, Sarah Cable, Gaya Connolly, Beth Coad, Andrea Forman, Helen Hanson, Grace Kavanaugh, Katherine Sahan, Katie Snape, Bethany Torr, Rosalind Way, Elizabeth Winchester, Alice Youngs, The International Lynch Decision Aid Stakeholder Panel, Diana Eccles, Claire Foster

“…Patient discussions were the primary data source. Facilitators provided a semi‐structured guide, but they did not influence the patient discussions or provide clinical advice. …”
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Understanding Care‐Seeking Behavior for Reproductive Tract Infections Among Afghan Women: A Cross‐Sectional Study by Cecilia Acuti Martellucci, Nooria Mohammady, Fawzia Negin, Sayed Hamid Mousavi, Adriana Viola Miranda, Husna Safa, Bibi Qudsia Qasimi, Khaterah Mosavi, Basira Bek, Alisina Azimi, Zahra Annabi, Saddiqa Noorzai, Aabidullah Rahimee, Taha Balaghat, Fatema Rezaie, Fardına Temory, Mirwais Ramozi, Mosè Martellucci, Rahila Bek, Shabanah Noorzai, Madina Niro, Husna Sultani, Palwasha Farooqi, Ehsan Shayan, Mohammadgul Zhwand, Qasem Rezaee, Farzana Torgani, Bibi Shakiba Hussaini, Shaqaiq Akhtiyari, Farah Qaderi, Shohra Qaderi

“…Methods From September 16, 2022 to November 26, 2022, a structured questionnaire was administered to women presenting at multi‐specialist clinics in the major cities of Afghanistan. …”
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‘It’s the perfect storm’: why are people with eating disorders at risk of suicide? A qualitative study by Una Foye, Saakshi Kakar, Niamh McNamara, Agnieszka Musial, Tom Jewell, Jessica R. Griffiths, Carol Kan, Gerome Breen, Rachel Rowan Olive, T. Suratwala, Aman Sidhu, Lizzie Mitchell, George Mycock, Katie Graden, Saskia Evans Perks, Elia Chitwa, Holly Whitehead, Ulrike Schmidt, Rina Dutta, Moritz Herle

“…Methods Using a qualitative design, we conducted semi-structured interviews with people with lived experience of an ED (n = 30), and clinicians who work with people with EDs (n = 19). …”
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Adherence to Mediterranean diet in Moroccan school-age adolescents: sociodemographic, socioeconomic and lifestyle determinants by Halima Belaoufi, Sanaa El-Jamal, Khadija Sahel, Abdelghani Aboukhalaf, Firdaous Friki, Hamid Chamlal, Jamila Elbiyad, Soumaya Atouife, Abdellah El Habazi, Rekia Belahsen

“…Material and methods A cross-sectional survey was conducted in a school setting among 386 students (148 boys and 238 girls), aged 14 to 18 years, randomly selected and from different socioeconomic strata. A structured questionnaire was used to collect sociodemographic, socioeconomic and lifestyle data. …”
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Knowledge, attitudes, and practices of people living in artisanal mining areas on water pollution in Siguiri, Guinea, 2023 by Aly Badara Toure, Aly Badara Toure, Mariama Sadjo Diallo, Mariama Sadjo Diallo, Sidikiba Sidibe, Sidikiba Sidibe, Salifou Talassone Bangoura, Salifou Talassone Bangoura, Fassou Mathias Grovogui, Fassou Mathias Grovogui, Fassou Mathias Grovogui, Maladho Diaby, Maladho Diaby, Mohamed Aly Bangoura, Yamoussa Youla, Mory Kourouma, Alexandre Delamou, Alexandre Delamou, Alexandre Delamou

“…The objective of this study was to analyze the knowledge, attitudes, and practices (KAP) of the population regarding water pollution in the mining areas of Siguiri, Guinea.MethodsA cross-sectional study was conducted from May 15 to June 15, 2023, on the population of Doko, Siguiri. Data were collected using a structured questionnaire that assessed knowledge, attitudes, and practices related to water pollution in artisanal mining areas. …”
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ADA2 is a lysosomal deoxyadenosine deaminase acting on DNA involved in regulating TLR9-mediated immune sensing of DNA by Ole Kristian Greiner-Tollersrud, Máté Krausz, Vincent Boehler, Aikaterini Polyzou, Maximilian Seidl, Ambra Spahiu, Zeinab Abdullah, Katarzyna Andryka-Cegielski, Felix Immunuel Dominick, Katrin Huebscher, Andreas Goschin, Cristian R. Smulski, Eirini Trompouki, Regina Link, Hilmar Ebersbach, Honnappa Srinivas, Martine Marchant, Georgios Sogkas, Dieter Staab, Cathrine Vågbø, Danilo Guerini, Sebastian Baasch, Eicke Latz, Gunther Hartmann, Philippe Henneke, Roger Geiger, Xiao P. Peng, Bodo Grimbacher, Eva Bartok, Ingrun Alseth, Max Warncke, Michele Proietti

“…Our study reveals that ADA2 localizes within the lysosomes, where it is targeted through modifications of its glycan structures. We show that ADA2 interacts with DNA molecules, altering their sequences by converting deoxyadenosine (dA) to deoxyinosine (dI). …”
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Patient and healthcare professionals’ perception of weekly prophylactic catheter washout in adults living with long-term catheters: qualitative study of the CATHETER II trial by John Norrie, Graeme Maclennan, David Cooper, Paul Little, Peter Murchie, Phyo Kyaw Myint, Mohamed Abdel-fattah, Mary Kilonzo, Muhammad Imran Omar, Diana Johnson, Sara J Maclennan, James Ndow, Graham Scotland, Amanda Young, Seonaidh Cotton, Nikesh Thiruchelvam, Catherine Paterson, Lynda Constable, Hashim Hashim, Sheela Tripathee, Konstantinos Dimitropoulos, Suzanne Evans, Karen Powell, James Hugh Larcombe

“…Data were analysed using the Theoretical Framework of Acceptability and Theoretical Domains Framework. …”
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Readiness for scale up following effectiveness-implementation trial: results of scalability assessment of the Community Partnership Program for diabetes self-management for older a... by Melissa Northwood, Tracey Chambers, Kathryn Fisher, Rebecca Ganann, Maureen Markle-Reid, Marie-Lee Yous, Ron Beleno, Gary Gaudet, Andrea Gruneir, Helen Leung, Craig Lindsay, Kasia Luebke, Gail Macartney, Ethel Macatangay, Janet MacIntyre, Carolyn MacPhail, William Montelpare, Allan Morrison, Lisa Shaffer, Martha St. Pierre, Frank Tang, Catharine Whiteside

“…Methods Multiple methods were used to assess the scalability of the CPP including collection and analysis of publicly available documents, synthesis of qualitative and quantitative evidence from studies of the CPP, semi-structured interviews with key informants, feedback and recommendations arising from working group meetings and knowledge exchange workshops to discuss and rate the scalability of the program. …”
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A Rare Case of Exophiala Dermatitidis Isolation in a Patient with Non-Cystic Fibrosis Bronchiectasis: Colonization or True Infection? by Francesco Rocco Bertuccio, Nicola Baio, Simone Montini, Valentina Ferroni, Vittorio Chino, Lucrezia Pisanu, Marianna Russo, Ilaria Giana, Elisabetta Gallo, Lorenzo Arlando, Klodjana Mucaj, Mitela Tafa, Maria Arminio, Emanuela De Stefano, Alessandro Cascina, Angelo Guido Corsico, Giulia Maria Stella, Valentina Conio

“…<b>Discussion:</b> This case underscores the diagnostic challenges in distinguishing fungal colonization from true infection in structurally abnormal lungs. In NCFB, disrupted mucociliary clearance and microbial dysbiosis may facilitate fungal persistence, even in the absence of overt immunosuppression. …”
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Constraints on self-interaction cross-sections of dark matter in universal bound states from direct detection by G. Angloher, S. Banik, G. Benato, A. Bento, A. Bertolini, R. Breier, C. Bucci, J. Burkhart, E. Cipelli, L. Canonica, A. D’Addabbo, S. Di Lorenzo, L. Einfalt, A. Erb, F. v. Feilitzsch, S. Fichtinger, D. Fuchs, A. Garai, V. M. Ghete, P. Gorla, P. V. Guillaumon, S. Gupta, D. Hauff, M. Ješkovský, J. Jochum, M. Kaznacheeva, A. Kinast, S. Kuckuk, H. Kluck, H. Kraus, A. Langenkämper, M. Mancuso, L. Marini, B. Mauri, L. Meyer, V. Mokina, M. Olmi, T. Ortmann, C. Pagliarone, L. Pattavina, F. Petricca, W. Potzel, P. Povinec, F. Pröbst, F. Pucci, F. Reindl, J. Rothe, K. Schäffner, J. Schieck, S. Schönert, C. Schwertner, M. Stahlberg, L. Stodolsky, C. Strandhagen, R. Strauss, I. Usherov, F. Wagner, V. Wagner, V. Zema, CRESST Collaboration

“…Abstract $$\varLambda $$ Λ -Cold Dark Matter ( $$\varLambda $$ Λ CDM) has been successful at explaining the large-scale structures in the universe but faces severe issues on smaller scales when compared to observations. …”
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Outpatient Virtual Care Among People Living With and Beyond Cancer From Culturally and Linguistically Diverse Backgrounds in Australia: A Protocol for a Realist Evaluation by Prince Peprah, Sagda Osman, Rebecca Mitchell, Ashfaq Chauhan, Ramya Walsan, Maryam Sina, Bronwyn Newman, Nadine El‐Kabbout, Jan Mumford, Emilie Francis‐Auton, Elizabeth Manias, Virginia Mumford, Kate Churruca, Michelle Moscova, Natalie Taylor, Craig Nelson, Alexander Cardenas, Robyn Clay‐Williams, Jeffrey Braithwaite, Reema Harrison

“…Phase 2 will use semi‐structured realist interviews and focus group discussions with stakeholders and retroductive, theory‐driven realist analysis to test and refine the initial program theory. …”
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Effects of biochar, ligneous soil amendments, and a microbial stimulant on soil biological activity, and carbon content and stability after two-years of their application in a bore... by J. Heinonsalo, K. Peltokangas, P. Barré, F. Baudin, L. Cécillon, S. Kalu, S. Kanerva, K. Karhu, L. Kulmala, J. Liski, A.-R. Salonen, R. Shrestha, H. Soinne, E. Virtanen, K. Huusko, O.-M. Sietiö

“…We investigated their impacts on soil organic carbon content and its stability, as well as on soil microbial abundance, activities, and community structures. Based on the extensive data we collected, mainly biochars increased soil organic carbon content enough to be detectable after two years. …”
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“A torch, a rope, a belly laugh”: engaging with the multiple voices of support groups for people living with rare dementia by Paul M. Camic, Emma Harding, Sam Rossi-Harries, Oliver S. Hayes, Mary Pat Sullivan, Lawrence Wilson, Nikki Zimmermann, Roberta McKee-Jackson, Joshua Stott, Nick C. Fox, Catherine J. Mummery, Jonathan D. Rohrer, Jason D. Warren, Rimona S. Weil, Sebastian James Crutch

“…The aim of the present study was to explore and better understand what the concept of support means for people living with different rare dementia (PLwRD) and their care-partners who attend ongoing support groups.MethodsRepresenting seven types of rare dementia, source material was collected from 177 PLwRD and care-partners attending in-person support groups, with the goal of developing research-informed group poems, co-constructed by a facilitating poet. Data were analyzed through a three-step process involving linguistic analysis followed by structured-tabular thematic analysis, relational analysis, and concluded with an online survey about participation in the study.ResultsLinguistic analysis found that co-constructed poems remained faithful to the original source material offered by participants. …”
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