Machine learning enhanced metal 3D printing: high throughput optimization and material transfer extensibility by Yuanjie Zhang, Cheng Lin, Yuan Tian, Jianbao Gao, Bo Song, Hao Zhang, Min Wang, Kechen Song, Binghui Deng, Dezhen Xue, Yonggang Yao, Yusheng Shi, Kun Kelvin Fu

“…The high throughput methodologies are mostly on obtaining the printed samples and their structural and physical properties, while ML is used for data analysis by model building for prediction (optimization), and understanding. …”
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MAPT-A152T mutation drives neuronal hyperactivity through Fyn-NMDAR signaling in human iPSC-Derived neurons: Insights into Alzheimer's pathogenesis by Maika Itsuno, Hirokazu Tanabe, Etsuko Sano, Takashi Sasaki, Chisato Oyama, Hiroko Bannai, Koichi Saito, Kazuhiko Nakata, Setsu Endoh-Yamagami, Hideyuki Okano, Sumihiro Maeda

“…In addition, transcriptomic analysis revealed structural changes specific to excitatory neurons with the A152T mutation. …”
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OptiNeoCare: optimisation of routine care in the management of severe perinatal asphyxia in full-term or near-term newborns – study protocol for analysis of suboptimal care by conf... by Pierre-Yves Ancel, Thierry Debillon, Gilles Cambonie, Geraldine Favrais, Gilles Kayem, Hendy Abdoul, Ayoub Mitha, Isabelle Guellec, Gauthier Loron, Charles Garabedian, Thomas Desplanches, Pierre Delorme, Eric Verspyck, Cyril Huissoud, Marie Delnaud, Blanche Graesslin, Pierre Tourneux, Maliha Badr, Sophie Chapeliere, Marie Brasseur-Daudruy, Max Gonzalez Estevez, Agnes Rigouzzo

“…The quality of care will be assessed based on a structured classification of medical errors (diagnostic, therapeutic, preventive and systemic) by a panel of experts including an obstetrician or midwife and a paediatrician. …”
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Genetically predicted white matter microstructure mediates the relationship between risk factors and lacunar stroke by Qing Ye, Jie Zhang, Li Zhang, Benyan Luo, Xiangming Ye, Min Wu, Wenshi Wang, Yue Zou, Douglas Neville, Kaisi Ren, Shuchang Zhong, Haiying Xiang

“…MD and ISOVF in the ALIC may serve as structural brain reserves and early biomarkers of hypertension-induced pathophysiology associated with lacunar stroke.…”
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Comparative Analysis of Plasma Protein Dynamics in Women with ST-Elevation Myocardial Infarction and Takotsubo Syndrome by Shafaat Hussain, Sandeep Jha, Evelin Berger, Linnea Molander, Valentyna Sevastianova, Zahra Sheybani, Aaron Shekka Espinosa, Ahmed Elmahdy, Amin Al-Awar, Yalda Kakaei, Mana Kalani, Ermir Zulfaj, Amirali Nejat, Abhishek Jha, Tetiana Pylova, Maryna Krasnikova, Erik Axel Andersson, Elmir Omerovic, Björn Redfors

“…Differential expression and functional significance were assessed. Data are accessible on ProteomeXchange, ID PXD051367. …”
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Coronary inflammation and atherosclerosis by CCTA in young adults (aged 18-45) by Annalisa Filtz, Daniel Lorenzatti, Henry A Dwaah, Carlos Espiche, Santiago F Galgani, Jake T Gilman, Alexandrina Danilov, Andrea Scotti, Piotr J Slomka, Daniel S Berman, Salim S Virani, Mario J Garcia, Khurram Nasir, Leslee J. Shaw, Ron Blankstein, Michael D Shapiro, Damini Dey, Leandro Slipczuk

“…Structured abstract: Background: Peri-coronary adipose tissue attenuation (PCAT), a marker of coronary inflammation, is linked to coronary artery disease (CAD), but data on the role of PCAT in young individuals are limited. …”
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Cognitive gains and cortical thickness changes after 12 weeks of resistance training in older adults with low and high risk of mild cognitive impairment: Findings from a randomized... by Simona Kušleikienė, Gal Ziv, Wouter A.J. Vints, Erika Krasinskė, Milda Šarkinaite, Orgesa Qipo, Ivan Bautmans, Uwe Himmelreich, Nerijus Masiulis, Vida J. Česnaitienė, Oron Levin

“…Background: In this randomized controlled trial, we assessed the neuroprotective effect of a 12-week resistance training (RT) program on executive control and cortical thickness of the prefrontal, temporal, parietal, and central cortex, regions prone to structural decline in individuals with mild cognitive impairment (MCI). …”
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Impact of shared decision-making in Taiwanese patients with atrial fibrillation eligible for novel oral anticoagulant therapy by Yen-Wen Wu, Tsung-Hsien Lin, Yuan-Po Yang, Wei-Tsung Wu, Chung-Ming Tu, Hung-Kain Huang, Chun-Yuan Chu, Chi-Cheng Huang, Szu-Chi Chien, Shih-Jie Jhuo, Ching-Pei Chen

“…During Stage I, part I participants (n = 124) completed a semi-structured survey (understanding evaluation sections only) before and after viewing SDM materials on stroke prevention for AF. …”
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Clinical relevance of loss-of-function mutations of NEMO/IKBKG by Jin Wang, Kexin Shen, Hongxia Lou, Lina Zhou, Yunfei An, Xiaodong Zhao, Yuan Ding

“…Almost all cases of hyper-IgM occurred in patients with EDA-ID. Different structural domains correspond to symptoms with varying degrees of severity. …”
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Co-designing and testing the learn together guidance to support patient and family involvement in patient safety investigations: a mixed-methods study by Jane O’Hara, Lauren Ramsey, Siobhan McHugh, Joseph Langley, Justin Waring, Ruth Simms-Ellis, Gemma Louch, Jenni Murray, Carl Macrae, John Baker, Rebecca Lawton, Daisy Halligan, Olivia Rogerson, Penny Phillips, Debra Hazeldine, Sarah Seddon, Joanne Hughes, Rebecca Partridge, Katherine Ludwin, Laura Sheard

“…Stage 2B synthesised previous data to develop common principles and programme theory. …”
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Knowledge, attitudes, and referral practices regarding animal bites and prevention of human rabies among Traditional Health Practitioners in the eThekwini District in KwaZulu-Natal... by Maxwell Mabona, Maxwell Mabona, Maxwell Mabona, Thembekile Zwane, Babongile Mhlongo, Lazarus Kuonza, Lazarus Kuonza, Poncho Phafane, Poncho Phafane

“…Our study aimed to assess the knowledge, attitudes, and referral practices regarding human rabies and the associated factors among THPs in eThekwini District, KwaZulu-Natal.MethodsA cross-sectional study was conducted among registered THPs in eThekwini District, collecting data through a structured, standardized questionnaire. …”
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Human gut microbiota adaptation to high-altitude exposure: longitudinal analysis over acute and prolonged periods by Xianzong Ma, Changwei Duan, Xiaoying Wang, Yurong Tao, Lang Yang, Yongsheng Teng, Yuanming Pan, Mingjie Zhang, Junfeng Xu, Jianqiu Sheng, Xin Wang, Peng Jin

“…In summary, acute high-altitude exposure caused dramatic changes in gut microbiota, while prolonged exposure led to structural and functional reshaping. These findings enhance our understanding of how high-altitude environments reshape gut microbiota.IMPORTANCEThis study is the first to investigate the impact of high-altitude exposure on gut microbiota adaptation in a large-scale longitudinal cohort. …”
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A qualitative study on the experience of nurses in the health education for patients with ulcerative colitis based on the Ottawa decision support framework (基于渥太华决策支持框架的护士参与溃疡性结肠炎患... by LIANG Zhuolin (梁琢琳), LI Xumiao (李旭苗), WEI Rongsai (魏荣赛), LIU Jingying (刘璟莹), ZHANG Nan (张楠), MA Hongwen (马宏文)

“…Through purposive sampling, semi-structured interviews were conducted with 11 nurses from the Department of Gastroenterology. …”
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Magnetic Resonance Imaging as a Readout of CLN5 Gene Therapy Efficacy in Sheep by Samantha J. Murray, Mustafa M. Almuqbel, Simon A. Felton, Nickolas J. Palmer, Ashley R. Deane, Daniel J. Myall, Reza Shoorangiz, Arsène Ella, Matthieu Keller, David N. Palmer, Tracy R. Melzer, Nadia L. Mitchell

“…Method Sheep treated at a pre‐symptomatic timepoint underwent five T1‐weighted structural MRI scans between 5 and 18 months of age. …”
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Genetic influences on the association between DNA methylation and obesity measures: insights from a twin study design by Xuanming Hong, Hui Cao, Weihua Cao, Jun Lv, Canqing Yu, Tao Huang, Dianjianyi Sun, Chunxiao Liao, Yuanjie Pang, Runhua Hu, Ruqin Gao, Min Yu, Jinyi Zhou, Xianping Wu, Yu Liu, Shengli Yin, Wenjing Gao, Liming Li

“…Despite more than a thousand of obesity-related DNAm sites (CpGs) being identified, studies that account for genetic influences in these associations are limited. Results Using data from 1,074 twins in the Chinese National Twin Registry and bivariate structural equation models (SEMs), we investigated the phenotypic (Rph), genetic (Ra), and environmental (Re) correlations between genome-wide DNAm and three obesity indices: BMI, waist circumference (WC), and waist-to-hip ratio (WHR). …”
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The Boost Team: transforming outreach for female veterans in rural communities by Jenny Krause Cohen, Jenny Krause Cohen, Kara Zamora-Rogoski, Caitlin McLean, Mariam Jacob, Tara Stacker, Caroline Dancu, Caroline Dancu, Jennifer Childers

“…Of Veterans who received the outreach, 58 completed a telephone survey using the Patient Empowerment Engagement Activation Survey (PEEAS), and 21 completed a semi-structured interview. Interviews focused on experiences with the NP, Boost's impact on access to and experience of VHA care, and suggestions for program improvement. …”
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Prevalence of blood-borne virus infections and uptake of hepatitis C testing and treatment in Australian prisons: the AusHep studyResearch in context by Rugiatu Bah, Yumi Sheehan, Xiaoying Li, Gregory J. Dore, Jason Grebely, Andrew R. Lloyd, Behzad Hajarizadeh, Andrew Lloyd, Behzad Hajarizadeh, Yumi Sheehan, Rugi Bah, Charlotte Li, Marianne Byrne, Tony Butler, Bridget Musarurwa, Elmira Hooshmand, Annabeth Simpson, Meya Alrayyani, Jason Grebely, Greg Dore, Nikki Price, Melissa Groom

“…Methods: Randomly-selected participants from 23 representative prisons nationally were offered point-of-care testing for HIV and HCV (anti-HCV) antibodies, hepatitis B surface antigen (HBsAg), and HCV RNA (if anti-HCV positive). Demographic data and previous HCV testing and treatment were collected by structured interview. …”
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Prospectively investigating the impact of AI on shared decision-making in post kidney transplant care (PRIMA-AI): protocol for a longitudinal qualitative study among patients, thei... by Peter Dabrock, David Samhammer, Zeineb Sassi, Sascha Eickmann, Sebastian Möller, Roland Roller, Bilgin Osmanodja, Aljoscha Burchardt, Klemens Budde, Anne Herrmann

“…Assuming a dropout rate of 20% per year, it is anticipated that 30 patient–SP dyads will be included in the last follow-up with the aim of achieving data saturation. Interviews will be audio-recorded and transcribed verbatim. …”
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Rationale and methodology of a multicentric prospective cohort study on ‘Longitudinal Effects of Air Pollution Exposure on Adolescent Lungs (APEAL)’ in urban India: APEAL protocol... by George D’Souza, Anant Mohan, Padukudru Anand Mahesh, Amruta Nori-Sarma, Harish C Phuleria, Gregory Wellenius, Twinkle Agrawal, Rajesh Thimmulappa, Biligere Siddaiah Jayaraj, Minu Rose Mani, Swapnali Patil, Priya Samdarshi

“…After quality checks, data will be compiled, summarising pulmonary function parameters alongside covariates and confounders. …”
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An inner membrane complex protein IMC1g in Plasmodium berghei is involved in asexual stage schizogony and parasite transmission by Yinjie Liu, Shitong Cheng, Gang He, Dawei He, Duo Wang, Sicong Wang, Lumeng Chen, Liying Zhu, Yonghui Feng, Liwang Cui, Yaming Cao, Xiaotong Zhu

“…Additionally, we confirmed that IMC1g is functionally conserved in Plasmodium spp. These data reveal the function of IMC1g protein in anchoring the glideosome, providing further insight into the mechanism of the glideosome function.…”
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