Deep learning-based computational approach for predicting ncRNAs-disease associations in metaplastic breast cancer diagnosis by Saleem Ahmad, Imran Zafar, Shaista Shafiq, Laila Sehar, Hafsa Khalil, Nida Matloob, Mehvish Hina, Sidra Tul Muntaha, Hamid Khan, Najeeb Ullah Khan, Samreen Rana, Ahsanullah Unar, Muhammad Azmat, Muhammad Shafiq, Yousef A. Bin Jardan, Musaab Dauelbait, Mohammed Bourhia

“…SHAP analysis identified key sequence motifs (e.g., "UUG") and structural free energy (ΔG = − 12.3 kcal/mol) as critical predictors, validated by PCA (82% variance) and t-SNE clustering. …”
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Assessment of Methicillin-Resistant Staphylococcus aureus (MRSA) knowledge and awareness among healthcare workers in South-Lebanon by Ali El Roz, Taghrid Chaaban, Hawraa Issa, José-Noel Ibrahim, Zeinab Ezzeddine, Ghassan Ghssein

“…Methods: A total of 244 HCWs, including those in medical services (MS), paramedical services (PS), and non-medical services (NMS), were conveniently selected for this study. Data was gathered using a structured, validated questionnaire that explored their knowledge and awareness of MRSA risks, prevention measures, hand hygiene practices, and multidrug resistance. …”
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Decentralized fintech platforms adoption intention in cyber risk environment among GenZ: A dual-method approach using PLS-SEM and necessary condition analysis by Md Sharif Hassan, Nguyen Hong Mai, Nor Shaipah Abdul Wahab, Mohammad Bin Amin, Md Maruf Hassan, Judit Oláh

“…A total of 391 valid responses were received. The data were analyzed through partial least squares structural equation modeling (PLS-SEM) and necessary condition analysis (NCA). …”
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Comparison of Molnupiravir Exposure‐Response Relationships for Virology Response and Mechanism of Action Biomarkers With Clinical Outcomes in Treatment of COVID‐19 by Akshita Chawla, Ruthie Birger, Brian M. Maas, Youfang Cao, Hong Wan, Julie Strizki, Arthur Fridman, Amanda Paschke, Carisa deAnda, Wei Gao, Matthew L. Rizk, Wendy Painter, Wayne Holman, Susanne Sardella, George Painter, Julie A. Stone

“…Exposure‐response (E‐R) analyses for viral RNA mutation rate and virologic outcomes were conducted using data from three phase 2/3 studies of molnupiravir (P006, MOVe‐IN, and MOVe‐OUT). …”
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Improving Childhood Immunization Service Delivery in Cameroon: A Synthesis of Caregiver Experiences and Recommendations by Yauba Saidu, Jessica Gu, Budzi Michael Ngenge, Sangwe Clovis Nchinjoh, Amani Adidja, Nnang Edwidge, Nkwain Muteh, Clarence Mbanga, Diaby Ousmane, Andreas Njoh, Junie Flegere, Demba Diack, Emanuele Montomoli, Sue Ann Costa Clemens

“…Methods: A descriptive cross-sectional study was conducted, targeting caregivers of children brought to selected health facilities for immunization in all ten regions of Cameroon. Using structured questionnaires, data were collected from caregivers and analyzed using STATA version 13. …”
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Impact of Mothers' Weaning Knowledge, and Practice on Infants' Health: A National Assessment by Samar A. Amer, Alaa N. Nafee, Reham Alkharayef, Fahad A. Al Amri, Faten A. AlRadini, Reem C. Alanazi, J. Norah Alshathri, Summayah Alanazi, Jaffer Shah, Iman I. Aldebasi, Izere Salomon, Eman Elsayed Abd‐Ellatif, Khaled Moghib

“…Participants were recruited from primary healthcare centres across five regions of Saudi Arabia. Structured face‐to‐face interviews were used to collect data, and χ2 tests and multinomial logistic regression were used to look for links between what mothers knew, how they weaned their infants, and signs of their infants' health. …”
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Mapping rapeseed (Brassica napus L.) aboveground biomass in different periods using optical and phenotypic metrics derived from UAV hyperspectral and RGB imagery by Chuanliang Sun, Chuanliang Sun, Weixin Zhang, Genping Zhao, Qian Wu, Wanjie Liang, Ni Ren, Hongxin Cao, Lidong Zou, Lidong Zou

“…Vegetation indices (VI), texture features (TF), and structural features (SF) were extracted from UAV hyperspectral and ultra-high-resolution RGB images to assess their correlation with rapeseed biomass at different growth stages. …”
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Changes in dietary intake during Ramadan month among university students in Bangladesh: a cross-sectional study by Mohammad Delwer Hossain Hawlader, Koustuv Dalal, Md. Kamrul Hasan, Humayun Kabir, Somayea Sultana Mim, Lamisa Rahman, Miah Mohammad Akiful Haque, Mamunur Rahman, Moez AlIslam E. Faris, Sahabi Kabir Sulaiman, Fatimah Isma’il Tsiga-Ahmed, Syed Fahad Javaid, Mariam Eisa Alseqetri, Moien A. B. Khan

“…Methods A cross-sectional study was conducted using a semi-structured questionnaire during the month of Ramadan in the year 2021 (10 May 2021 to 10 June 2021). …”
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Perspectives of researchers and clinicians on patient and public involvement (PPI) in preclinical spinal cord research: An interview study by Pádraig Carroll, Éimear Smith, Adrian Dervan, Ciarán McCarthy, Cliff Beirne, John Quinlan, Geoff Harte, Dónal O'Flynn, Fergal J. O'Brien, Frank Moriarty, Michelle Flood

“…This study aimed to explore the perspectives of two key stakeholder groups, preclinical researchers and clinicians on PPI in preclinical research, using spinal cord research as a case study. Methods Semi‐structured interviews were conducted online with 11 clinicians and 11 preclinical researchers all working in the area of spinal cord injury (SCI). …”
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Human microbiome-derived peptide affects the development of experimental autoimmune encephalomyelitis via molecular mimicryResearch in context by Xin Ma, Jian Zhang, Qianling Jiang, Yong-Xin Li, Guan Yang

“…Of note, half of these analogs could bind to MHC II and interact with TCR through structural modeling of the interaction using fine-tuned AlphaFold. …”
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Integrative DNA methylome and transcriptome analysis identify potential genes on the influence of dilated cardiomyopathy-associated heart failure by Zhenglong Guo, Yunfei Liu, Zhiming Zhou, Jianchao Chen, Lin Guo, Keke Liang, Yibin Hao, Bingtao Hao, Bin Yang, Shixiu Liao

“…Conclusions These findings suggest that the epigenetic dysregulation of cardiac stress-response and structural genes contributes to the pathogenesis of DCM-HF. …”
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Unravelling typology of family life when a parent has heart disease: A qualitative study of families with adolescents by Matilda Holmbom, Hanna Grundström, Frida Andréasson, Camilla Rotvig, Hege Andersen, Camilla Bernild, Tone Merete Norekvål, Selina Kikkenborg Berg, Anna Strömberg

“…Inclusion criteria were families with a parent living with any type of heart disease, within six months and up to five years since diagnosis and having one or more adolescents living at home. Methods: Data was collected through semi-structured individual interviews. …”
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A systematic review and meta-analysis: prevalence and clinical implications of anatomical variants of the hepatic portal vein by Juan José Valenzuela-Fuenzalida, Benjamín Rodríguez-Osorio, Cristian Salgado-Torres, Pablo Nova-Baeza, Mathias Orellana-Donoso, Alejandro Bruna-Mejías, Roberto Avila-Sepulveda, Álvaro Becerra-Farfán, Macarena Rodríguez-Luengo, Juan Sanchis-Gimeno, Guinevere Granite, Héctor Gutiérrez-Espinoza

“…Tree authors independently performed the search, study selection and data extraction. Methodological quality was evaluated with an assurance tool for anatomical studies. …”
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Spanish Nurses’ Knowledge and Perceptions of Climate Change: A Qualitative Study by Antonio Miguel Caraballo-Betancort, Irene Marcilla-Toribio, Blanca Notario-Pacheco, Maria Leopolda Moratalla-Cebrian, Ana Perez-Moreno, Alba del Hoyo-Herraiz, Raquel Poyatos-Leon, Maria Martinez-Andres

“…Purposive and snowball sampling strategies were used to recruit nurses from emergency services, geriatrics, cardiology, respiratory medicine and primary care in nine different regions of Spain. Semi-structured online interviews were conducted. Data analysis was carried out by three researchers via a three-stage inductive thematic analysis approach. …”
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Ophthalmologists’ and patients’ perspectives on treatments for diabetic retinopathy and maculopathy in Vietnam: a descriptive qualitative study by Tunde Peto, Nathan Congdon, Lynne Lohfeld, Hoang Tran, Katie Curran, Van Thu Nguyen, Tung Thanh Hoang, Hue Thi Nguyen, Quan Nhu Nguyen, Catherine Dardis, Hoang Huy Tran, Anh Tuan Vu, Mai Quoc Tung

“…Thematic analysis was used to analyse the data.Results In total, 10/24 (41.7%) ophthalmologists were female, and their median age was 41 years (range 29–69 years). …”
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Strengthening the delivery of integrated care for individuals experiencing serious mental illness within mental health settings: a qualitative description of health provider perspe... by Munazzah Ambreen, Christopher Canning, Brian Lo, Sri Mahavir Agarwal, Amer M. Burhan, David Castle, M. Elisabeth Del Giudice, Barna Konkolÿ-Thege, Louis Liu, Osnat C. Melamed, Frank Sirotich, Sanjeev Sockalingam, Gillian Strudwick, Tania Tajirian, Philip G. Tibbo, Mary Rose van Kesteren, Caroline Walker, Vicky Stergiopoulos

“…Methods This qualitative descriptive study involved conducting individual semi-structured interviews with 13 health administrators and four focus groups with 15 clinicians between July 2023 and April 2024. …”
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Cost-effectiveness of FIT and a FIT-based model to optimise symptomatic diagnosis of colorectal cancer: health economic modelling for the COLOFIT project by Linda Sharp, Sarah Bailey, Colin Rees, Willie Hamilton, Dawn Craig, Joe West, David Humes, Gary Abel, James Turvill, Brian Nicholson, Chloe Thomas, Jim Chilcott, Colin Crooks, Olena Mandrik, John Whelpton

“…Cost-effectiveness improves as risk thresholds rise. High structural uncertainty around cancer progression during diagnostic delay and diagnosis of other serious bowel diseases considerably affects cost-effectiveness.Conclusions COLOFIT is likely to be more cost-effective than FIT alone and could help alleviate pressure on diagnostic services. …”
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Impact of residential density on heavy metal mobilization in urban soils: Human activity patterns and eco-health risks in the Beijing-Tianjin-Hebei region by Siyu Wang, Lingqing Wang, Xiaoyong Liao, Guangjin Zhou, Yizhong Huan, Shun Li, Tao Liang

“…Co-occurrence network and Partial Least Squares Structural Equation Modeling (PLS-SEM) suggested that human activities may indirectly influence metal dispersion by altering soil organic carbon (TOC) and nitrogen dynamics, rather than directly increasing bulk metal content. …”
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Immunization Coverage and Barriers among Hajj and Umrah Pilgrims: Insights into Vaccine Uptake and Compliance by Adeeb A. Bulkhi, Hani M. Almoallim, Majed S. Obaid, Nahla H. Hariri, Hamsah S. Alqashqri, Ismail A. Alghamdi, Amar Mohammad A. Alkhotani, Muhammad Irfanullah Siddiqui, Heba M. Adly, Mohammed A. Garout, Elbagir A. Elfaki, Saleh A. K. Saleh, Noura Mohammed Bakhsh, Raghda Sami Hassan H. Alhazmi, Aous S. Alhazmi, Jaffar A. Al-Tawfiq, Fahad A. Alamri, Anas A. Khan

“…Methods A cross-sectional study was conducted during the 2024 Hajj season, with data collected via structured interviews from 5,355 participants. …”
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Embracing Growth, Adaptability, Challenges, and Lifelong Learning: A Qualitative Study Examining the Lived Experience of Early Career Nurses by Liz Ryan, Di Stratton-Maher, Jessica Elliott, Tracey Tulleners, Geraldine Roderick, Thenuja Jayasinghe, Joanne Buckley, Jamie-May Newman, Helen Nutter, Jo Southern, Lisa Beccaria, Georgina Sheridan, Danielle Gleeson, Haiying Wang, Sita Sharma, Jing-Yu (Benjamin) Tan, Linda Ng, Blake Peck, Tao Wang, Daniel Terry

“…Thematic analysis was used to analyse data while adhering to the consolidated criteria for reporting qualitative research (COREQ) guidelines. …”
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