Seeking Correlation Among Porin Permeabilities and Minimum Inhibitory Concentrations Through Machine Learning: A Promising Route to the Essential Molecular Descriptors by Sara Boi, Silvia Puxeddu, Ilenia Delogu, Domenica Farci, Dario Piano, Aldo Manzin, Matteo Ceccarelli, Fabrizio Angius, Mariano Andrea Scorciapino, Stefan Milenkovic

“…The automated protocol presented here could be used to inspect, in silico, many alternatives of a given molecular structure, with the output being the list of the best candidates to be then synthesized and tested. …”
Get full text

Interface characterization of Cu18150/Al1060/Cu18150 laminated composite produced by combined cast-roll and hot-roll technique by Mahmoud Ebrahimi, Yuchao Zhao, Huisheng Cai, Shokouh Attarilar, Zhengping Shang, Qudong Wang

“…Scanning electron microscopy (SEM) and energy-dispersive spectroscopy (EDS) analyses elucidate the formation of IMCs at the interfaces, with predicted formation sequences influenced by Gibbs free energy data. Electron backscatter diffraction (EBSD) analysis indicates that hot rolling promotes grain refinement in Cu18150, resulting in a homogeneous structure with elongated fine grains, while Al1060 shows nonuniform grain distribution. …”
Get full text

Identification and Analysis of <i>KAS II</i>, <i>FAT</i>, <i>SAD</i>, and <i>FAD</i> Gene Families in <i>Hippophae rhamnoides</i> by Alexander A. Arkhipov, Ekaterina M. Dvorianinova, Anastasia A. Turba, Roman O. Novakovskiy, Yury A. Zubarev, Pavel A. Predushchenko, Elizaveta A. Sigova, Daiana A. Zhernova, Elena V. Borkhert, Elena N. Pushkova, Chengjiang Ruan, Nataliya V. Melnikova, Alexey A. Dmitriev

“…As a result of structure and phylogenetic analyses, 4 <i>KAS II</i>, 8 <i>FAT</i>, 9 <i>SAD</i>, and 12 <i>FAD</i> genes were identified in the <i>H. rhamnoides</i> genome, which were classified into subfamilies: <i>KAS II, FATA</i>, <i>FATB</i>, <i>FAD2</i>, <i>FAD3</i>, <i>FAD6</i>, and <i>FAD7/8</i>. …”
Get full text

Differential effects of oral versus intravenous hydrocortisone and dexamethasone on capillary blood glucose levels in adult inpatients − a single centre study by Vaishali Limbachia, Ian Nunney, Daniel J. Page, Hannah A. Barton, Leena K. Patel, Georgia N. Thomason, Stephan L. Green, Kieran F.J. Lewis, Ketan Dhatariya

“…An auto-regressive covariance structure was employed to model correlations between repeated measurements. …”
Get full text

Quality of Care of Adult Patients With Allergic Diseases in Urban, Rural, and Remote Primary Care Sites in the Philippines by Carol Stephanie C. Tan-Lim, Robbi Miguel G. Falcon, Jeremiah F. Feliciano, Michael B. Fong MD, Mark Anthony U. Javelosa, Leonila F. Dans, Iris Thiele C. Isip-Tan, Josephine T. Sanchez, Mia P. Rey, Antonio Miguel L. Dans

“…Methods: This was a retrospective review of electronic health records of all adult patients who consulted in the 3 sites from May 2019 to April 2022. Data of adult patients with allergic diseases was extracted from the 3 EHR systems operating across the participating sites using standardized Structured Query Language queries across the 3 systems. …”
Get full text

Whole-Genome Resequencing to Identify Selection Signatures Associated with High Fertility in Lüliang Black Goat by Xu Wang, Zhenqi Zhou, Xinrui Chai, Jie Li, Wannian Wang, Zhixu Pang, Lifen Cheng, Caihong Cheng, Liying Qiao, Yangyang Pan, Kaijie Yang, Wenzhong Liu, Jianhua Liu

“…Based on whole-genome resequencing data, this study comprehensively assessed the population structure and genetic diversity of LBG and explored the related genes that affect reproductive performance. …”
Get full text

Technical note: Flow cytometry assays for the detection, counting and cell sorting of polyphosphate-accumulating bacteria by C. Bouquet, H. Billard, H. Billard, C. C. Bidaud, J. Colombet, J. Colombet, Y.-T. Chang, J. Artigas, I. Batisson, K. Benzerara, F. Skouri-Panet, E. Duprat, A.-C. Lehours

“…This requires high-throughput methods to characterize their structure and dynamics in ecosystems. A promising strategy is to combine the staining of intracellular polyphosphate granules and their subsequent detection by flow cytometry, enabling rapid data acquisition. …”
Get full text

Contextual factors in value-based decision support to enhance health technologies adoption: the case of biosimilars by Maximilian Otte, Maximilian Otte, Maximilian Otte, Zoltán Kaló, Zoltán Kaló, Zoltán Kaló, Hussain Abdulrahman Al-Omar, Meindert Boysen, Yingyao Chen, Ana Paula Beck Da Silva Etges, Ana Paula Beck Da Silva Etges, Guvenc Kockaya, Iñaki Gutierrez-Ibarluzea, Ahmed Mohammed Seyam, Deirdre Mullen, Deirdre Mullen, Hans-Peter Dauben, Hans-Peter Dauben, Hans-Peter Dauben

“…The MCDA framework offers a structured approach to operationalize these principles. …”
Get full text

Erythritol as a Next-Generation Sweetener: properties, metabolism, cardiovascular risk and gut health implications – A literature review by Julia Skowrońska-Borsuk, Martyna Narożniak, Adrianna Ewa Pękacka, Bartłomiej Czerwiec, Adam Borsuk, Joanna Katarzyna Pergoł, Malwina Wojtas, Julia Borkowska, Zuzanna Krupa, Julia Sposób

“…However, these findings are inconclusive and require further investigation. Emerging animal data indicate erythritol may modulate gut epithelial structure via microbiota-derived metabolites. …”
Get full text

Anti-Migratory Activity of Brazilin Chemodiversification on Breast Cancer Cells by Alberto Hernández-Moreno, Dania A. Nava-Tapia, Miriam D. Zuñiga-Eulogio, Jorge Bello-Martínez, Monserrat Olea-Flores, Tadeo Hernández-Moreno, Mario Ordoñez, Ana E. Zacapala-Gómez, Miguel A. Mendoza-Catalán, Napoleón Navarro-Tito

“…In this study, we isolated brazilin from the heartwood of <i>Haematoxylum brasiletto</i>; then, we performed a semi-synthesis by adding three methyl or acetyl groups to the core structure of brazilin. We confirmed the identity of brazilin and its derivatives by spectroscopic data (¹H NMR and ¹³C NMR) and measured their purity by optical rotation. …”
Get full text

An effective fluorescence strategy based on xanthine oxidase catalysis and the carbon dots’ specific response to ·OH for aminophylline pharmacokinetic studies by Chenfang Miao, Menghan Zhang, Ying Zheng, Xiaoyan Lin, Shuangying Yang, Linlin Xu, Sitong Lu, Zhengjun Huang, Jianyong Huang, Yanjie Zheng, Shaohuang Weng

“…In this study, high quantum yield carbon dots (CA/EDA-CDs) were synthesized via a hydrothermal method using riboflavin as the carbon source, citric acid and ethylenediamine as functionalizing agents and dopants. The luminescent structure of CA/EDA-CDs, featuring a π-conjugated system (aromatic C=C and graphite N) and surface chromophores (C=N/C=O) connected via C-N, C-O, and hydrogen bonds, was controllably modulated by hydroxyl radical (·OH). …”
Get full text

Orthopaedic Consultation is Associated With Fewer Patient-Perceived Barriers to Total Joint Arthroplasty by Insa Mannstadt, BS, BA, J. Alex B. Gibbons, BA, Troy B. Amen, MD, MBA, Mangala Rajan, PhD, Sarah R. Young, PhD, Henry Tischler, MD, Michael L. Parks, MD, Mark Figgie, MD, Anne Bass, MD, Linda Russell, MD, Bella Mehta, MD, MS, Iris Navarro-Millán, MD, Susan M. Goodman, MD

“…Methods: We performed a post-hoc analysis of questionnaire responses based on data from a previous study that used semi-structured interviews with patients with advanced osteoarthritis. …”
Get full text

ASSESSMENT OF THE PSYCHOLOGICAL STATUS OF PATIENTS WITH GYNECOLOGICAL CANCER IN THE PROCESS OF PSYCHOLOGICAL REHABILITATION by E. V. Pestereva, V. A. Chulkova, T. Y. Semiglazova, E. G. Ulrich, O. A. Pestereva

“…Disturbing component in patients at the stage of «before operation» and dysphoric component in patients at the stage of «after surgery» were dominated on the background of ergopathic reactions to the disease in the structure of attitude to the disease. The high intensity of complaints of female patients about their health, including non-specific, indicating the psychosomatic component of the patient’s suffering was revealed. …”
Get full text

Inaccuracies of venous thromboembolism risk assessment and prevention practices among medically ill patients by Brandyn D. Lau, Aditya Bhave, Jennifer C. Yui, Rakhi Naik, Kathryn E. Dane, John Lindsley, Dauryne L. Shaffer, Peggy S. Kraus, Erik H. Hoyer, Elliott R. Haut, Michael B. Streiff

“…Leveraging existing structured data to autopopulate VTE risk assessments can assist providers in improving accuracy. …”
Get full text

Fundamental Parameters for Totally Eclipsing Contact Binaries Observed by TESS by Xu Ding, KaiFan Ji, ZhiMing Song, XueFen Tian, JinLiang Wang, ChuanJun Wang, QiYuan Cheng, JianPing Xiong

Get full text

Investigating an Erupting Metric-decimetric Radio Depression and Its Physical Origin by B. T. Wang, X. Cheng, J. Y. Yan, C. Xing, W. T. Fu, L. Wu, L. Deng, A. L. Lan, Y. Chen, C. Wang, M. D. Ding

“…At the radio band, even though the filament is difficult to identify in its early phase, it rapidly became distinct and formed a continuous loop-like dark structure during the eruption, i.e., so-called radio depression. …”
Get full text

Occupational health and safety regulations in China: development process, enforcement challenges, and solutions by Xinyu Xu, Xinyu Xu, Xinyu Xu, Peihua Ren, Peihua Ren, Wenyan Shi, Wenyan Shi, Feidan Deng, Feidan Deng, Qingfeng Wang, Qingfeng Wang, Shaoteng Shi, Shaoteng Shi, Jingchun Shen, Jingchun Shen, Guoqiang Dong, Jing Han, Jing Han, Jing Han, Jing Han

“…The purpose of this paper is to summarize the current health status of China’s occupational population and the dilemmas faced by prevention and treatment work.MethodsThe following databases were utilized: China National Knowledge Infrastructure (CNKI), Wanfang Data, PubMed, Web of Science, Scopus, and Google Scholar. …”
Get full text

Unveiling the charge density wave mechanism in vanadium-based Bi-layered kagome metals by Yi-Chen Yang, Soohyun Cho, Tong-Rui Li, Xiang-Qi Liu, Zheng-Tai Liu, Zhi-Cheng Jiang, Jian-Yang Ding, Wei Xia, Zi-Cheng Tao, Jia-Yu Liu, Wen-Chuan Jing, Yu Huang, Yu-Ming Shi, Soonsang Huh, Takeshi Kondo, Zhe Sun, Ji-Shan Liu, Mao Ye, Yi-Lin Wang, Yan-Feng Guo, Da-Wei Shen

“…Our finding not only comprehensively maps the electronic structure of V-based bi-layer kagome metals but also provides constructive experimental evidence for the unique origin of CDW in this system.…”
Get full text

Physical activity, screen time, and sleep quality of students during remote learning by Elias dos Santos Batista, Helder Xavier Bezerra, Gabriel Pereira Maciel, Alesandra Araújo de Souza, Marcela Rodrigues de Castro, Valter Cordeiro Barbosa Filho, Rodrigo Ramalho Aniceto

“…An online questionnaire was structured, including recall information about behaviors before and during remote learning. …”
Get full text

Optimal suturing techniques in patch-bridging reconstruction for massive rotator cuff tears: A finite element analysis by Yuting Zhong, Chengxuan Yu, Sijia Feng, Han Gao, Luyi Sun, Yunxia Li, Shiyi Chen, Jun Chen

“…The ultimate failure load, failure mode, stress distribution of each structure, and other biomechanical results of the different models were calculated and compared. …”
Get full text