A comprehensive review on novel opportunities for Alzheimer therapy by targeting BIN1 by Trina Saha, Dipanjan Karati

“…Conclusion The most frequent BIN1 variants are found in non-coding regions immediately upstream of the gene, and it is thus likely that their impact is regulatory and not structural. The variants can influence the levels of BIN1 or splicing between isoforms, especially the distribution of isoforms. …”
Get full text

Development of an intervention for smoking cessation in pregnant women using a theory-based approach by Estelle Clet, Adrianna Burtin, Nolwenn Stevens, Charlotte Kervran, Rebecca Ratel, Manon Vergneau, Perrine Moysan, Manon Frevol, Loïc Sentilhes, Philippe Castera, François Alla, 5A-QUIT-N groupx

“…Next, obstacles and levers that could influence their implementation and effectiveness were identified through a scoping review and semi-structured interviews. The resulting data were then used to design the first version of the intervention. …”
Get full text

Comorbidity-driven COPD outcomes: the urgent need for full optimisation by respiratory physicians by Sobia Chaudhary, Sundeep Kaul

“…Routine, proactive screening for GERD, osteoporosis, PH, bronchiectasis and IHD should become a fundamental practice. Effective, structured referral pathways to pulmonary rehabilitation must be established, combined with integrated cardiopulmonary risk assessments and management protocols. …”
Get full text

Molecular Determinants for the Binding of the Highly Infectious SARS-CoV-2 Omicron (BA.1) Variant to the Human ACE2 Receptor by Majed S. Aljohani, Pawan Bhatta, Xiche Hu

“…Additionally, allosteric effects improve the contributions of non-mutated residues (notably A475, Y453, and F486) via structural realignment and novel hydrogen bonding with ACE2 residues such as S19, leading to an overall increase in the electrostatic and π-system interaction energy. …”
Get full text

Is non-conveyance solo-ambulances a useful mean to meet the increasing demand for emergency medical services in Denmark? by Frederikke Amalie Møller, Mads Lillethorup Persson, Elisabeth Larsen Engholm, Penille Horsbøl Kirkegaard Jensen, Ulla Vaeggemose, Tine Bennedsen Gehrt

“…Furthermore, 19 semi-structured interviews with paramedics, EMS dispatchers and technical dispatchers partaking in the operation of the PVU were conducted. …”
Get full text

“I found much more joy than I ever did as a player”– a qualitative study of the emotional journey of shattered dreams and new horizons with an ACL re-rupture in young active men... by Rebecca Hamrin Senorski, Anna Nordenholm, Emelie Dahlin, Kristian Samuelsson, Ramana Piussi, Eric Hamrin Senorski

“…Methods Eighteen males (19–33 years old) were interviewed with semi-structured interviews, which were recorded, transcribed, and analysed with qualitative content analysis, based on the method described by Graneheim and Lundman. …”
Get full text

Prevalence and factors associated with probable anxiety disorders among elderly persons living with HIV at Mulago ISS clinic: A cross-sectional study. by Anthony Muyunga, Kevin Ouma Ojiambo, Janet Nakigudde, Jovan Mugerwa, Benard Owori, Kevin Naturinda, Brian Mikka, Janet Peace Babirye, Namutale R Nalule, Isaac Samuel Kintu, Enos Kigozi, Caroline Birungi

“…Drug and clinical factors data were extracted from records, entered into Epidata, and later to STATA version 17 for analysis. …”
Get full text

Diversity and equity in medical education over the past decade: applications, matriculations, and the growing gaps by Gang Lv, Xiangxiang Jiang, Jordan Franklin, Minghui Li, Jing Yuan, Z. Kevin Lu

“…Methods This study used data from the Association of American Medical Colleges from 2015 to 2024. …”
Get full text

High frequency and duration of social media exposure during the COVID- 19 pandemic are associated with mental health problems among employees at an Egyptian university by Ghada O. Wassif, Mohamed Y. El-Awady, Mariam W. Nagi, Isis M. Mossad

“…Second, two faculties were randomly selected from each discipline to ensure representative sampling. Data were collected using a structured questionnaire, which included the Generalized Anxiety Disorder-7 (GAD-7) and the Patient Health Questionnaire-9 (PHQ-9) scales to assess anxiety and depression levels. …”
Get full text

Association of workplace support for health with occupational health literacy and illness avoidance: moderated mediation by functioning through a salutogenic lens by Nestor Asiamah, Isaac Aidoo, Etornam Doamekpor, Emelia Sarpong, Emelia Danquah, Cosmos Yarfi, Eric Eku, Usman Yaw Baidoo, Christiana Afriyie Manu, Rita Sarkodie Baffoe

“…., WSH, OHL, functioning, and illness avoidance) were measured with Likert-type scales adopted in whole from the literature. Data were analysed with Hayes’ Process Model through structural equation modelling. …”
Get full text

PSYCHOLOGICAL READINESS OF SECONDARY VOCATIONAL EDUCATION TEACHERS FOR MASTERING NEW ACTIVITIES IN THE CONTEXT OF PROFESSIONAL REORIENTATION by I. I. Khasanova, S. S. Kotova

“…The functionality of this technology, its tasks, structural components, possible methods and estimated effects of its implementation in practice of the SPE (Secondary Professional Education) system are noted.Practical significance. …”
Get full text

Types and Characteristics of Hair Across the Globe: Results of a Multinational Study on 19,461 Individuals by Flament F, Maudet A, Barbarat P, Jabnoun M, Bayer-Vanmoen M, Imbert legrain A, Leclerc-Mercier S, Taieb C, Skayem C, Lebarbanchon L

“…Participants completed a structured digital questionnaire evaluating hair thickness, type, damage, and curl degree, alongside questions on stress, sleep, and well-being. …”
Get full text

Molecular prevalence of Chlamydia trachomatis infection among women attending gynaecological clinic for infertility evaluation by Olufemi Olamakinwa Ala, Bukhari Isah Shuaib, Amina Momodu, Musa Abidemi Muhibi

“…Socio-demographic and clinical data were collected via structured questionnaires. …”
Get full text

Implementation of a spaced-repetition approach to enhance undergraduate learning and engagement in paediatrics by Keta Vagha, Sonali Choudhari, Amar Taksande, Jayshree Tembhurne, Jayant Vagha, Sunita Vagha

“…While widely used in self-directed learning, its role in structured medical education remains underexplored. …”
Get full text

Experiencias de enfermeras en el cuidado de personas diagnosticadas de anorexia nerviosa: un estudio cualitativo by Victoria Velasco-Cabrero, Julio González-Luis

“…A qualitative design will be used, specifically grounded theory, through in-depth semi-structured interviews, at the Institute of Psychiatry and Mental Health of the Gregorio Marañón University General Hospital. …”
Get full text

No vas a dejar el surf. Reflexiones sobre las motivaciones y condicionantes sociales que conducen a su práctica en entornos naturales y artificiales (You won't quit surfing. Reflec... by Diego Santos González

“…A comparative qualitative approach was adopted with a sample of 24 surfers, selected through intentional sampling and the snowball technique. Semi-structured, in-depth interviews were conducted to collect data, analyzed through thematic coding. …”
Get full text

Enhancing Accessibility in Philippine Public Bus Systems: Addressing the Needs of Persons with Disabilities by Ma. Janice J. Gumasing, Timothy Ray P. Del Castillo, Antoine Gabriel L. Palermo, Janred Thien G. Tabino, Josiah T. Gatchalian

“…Structural equation modeling (SEM) was used to analyze the hypothesized relationships between these variables, passenger satisfaction, and intention to reuse public transport. …”
Get full text

Diachronic changes in local food heritage: the ethnobiology of wild foods in central Tuscany by Mousaab Alrhmoun, Valter Guiggi, Syed Waseem Gillani, Muhammad Manzoor, Naji Sulaiman, Andrea Pieroni

“…This study explores shifts in wild food knowledge and practices over two decades, comparing data collected in 2024 with findings from a 2004 study. …”
Get full text

Viral activity in lake analogs of anoxic early Earth oceans by Natascha S. Varona, Bailey A. Wallace, Alice Bosco-Santos, Julianna Mullinax, Alexandra K. Stiffler, Molly D. O’Beirne, Josh Ford, James M. Fulton, Josef P. Werne, William P. Gilhooly, Cynthia B. Silveira

“…This suggests that viral lysis may contribute less to bacterial community structuring in these high-density microbial plates. …”
Get full text

AI-powered visual E-monitoring system for cattle health and wealth by Aung Si Thu Moe, Pyke Tin, Masaru Aikawa, Ikuo Kobayashi, Thi Thi Zin

“…A farm-side desktop application processes live video streams from 22 cameras using multiprocessing, maintaining an average latency of 0.62 s per frame per camera. Captured data are stored in a structured MySQL database and accessed via a RESTful API by a user-side mobile application developed using Flutter and Clean Architecture. …”
Get full text