TET dioxygenases localize at splicing speckles and promote RNA splicing by Florian D. Hastert, Jasmin Weber, Christina Bauer, Andreas Zhadan, Deepanshu N. D. Singh, Thomas C. Dix, Roland Arnold, Sergey Bessonov, Matthias Soller, Heinrich Leonhardt, M. Cristina Cardoso, Maria Arroyo

“…This study explores the relationship between RNA splicing and the TET dioxygenase activity, shedding light on the role of hm5C (RNA 5-hydroxymethylcytosine), and TET proteins in RNA metabolism. Integrating data from mass spectrometry, AlphaFold structural modeling, microscopic analysis, and different functional assays, including in vitro splicing, TET proteins were found to regulate splicing. …”
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Visual Impairment Among Undergraduates: A Situational Analysis of Eye Health in Bowen University Iwo, Nigeria by Olumide Thomas Adeleke, Akinsola Aina, Adewumi Oluwafemi Oyabambi, Timothy Samson, Oludamola Victoria Adeleke, Temitayo Aderemi Olabode, Ifeoluwasemilojo Aina, Oluwaseun Awe

“…Materials and methods: A cross-sectional study was conducted among 1407 undergraduate students at the institution. Data obtained includes sociodemographic characteristics, vital signs, and visual acuity using a structured questionnaire. …”
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Determinants of digital health literacy among older adult patients with chronic diseases: a qualitative study by Yujiao Shao, Xiumu Yang, Xiumu Yang, Qin Chen, Hongyan Guo, Xiaocui Duan, Xuejun Xu, Jianxing Yue, Zeyu Zhang, Shuang Zhao, Shiqing Zhang

“…ObjectiveThis study aimed to identify the factors influencing digital health literacy in older adult patients with chronic diseases.MethodsA descriptive qualitative approach incorporated purposive and snowball sampling methods. Semi-structured interviews were conducted with 32 older adult patients with chronic diseases from three hospitals in Anhui Province between October 2023 and May 2024. …”
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Same same but different: Neuroanatomic and connectomic profiles of early-onset schizophrenia and autism spectrum disorder by Bin Lu, Xue Li, Xue-Ping Gao, Jing Chen, Yi Liu, Jian-Ping Lu, Siu-Ching Kat, Zeng-Hui Ma, Li-Yang Zhao, Ting-Ni Yin, Xing Su, Fan-Chao Meng, Ya-Ru Zhang, Shu-Xian Wu, Wen-Jie Yan, Ya-Song Du, Xue-Rong Luo, Jing Liu, Chao-Gan Yan

“…Conclusion: The neuro-profiles revealed that EOS and ASD exhibit overlapping as well as unique imaging characteristics; however, EOS exhibits greater structural variation, while ASD presents with more subtle connectomic abnormalities. …”
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Fluid characteristics, gas accumulation controlling factors and gas enrichment modes in coal reservoirs: A case study of the Upper Paleozoic in the central-eastern Ordos Basin, NW... by Shida CHEN, Dazhen TANG, Wei HOU, Daojun HUANG, Yongzhou LI, Jianling HU, Hao XU, Shu TAO, Song LI, Shuling TANG

“…Based on the test and experimental data from exploration well cores of the Upper Paleozoic in the central-eastern Ordos Basin, combined with structural, burial depth and fluid geochemistry analyses, this study reveals the fluid characteristics, gas accumulation control factors and accumulation modes in the Upper Paleozoic coal reservoirs. …”
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Rebuilding lives in Nagaya, a public housing for older victims of the great East Japan earthquake: An interview survey by Naomi Ito, Yurie Kobashi, Yuri Kinoshita, Nobuaki Moriyama, Toshiki Abe, Hiroaki Saito, Isamu Amir, Chika Yamamoto, Mika Sato, Masaharu Tsubokura

“…The current interview survey aimed to report the living conditions of such older victims in Nagaya and accordingly suggest strategies for supporting the older population who experience disasters. We conducted semi-structured interviews with 32 Nagaya residents, who relocated there due to the earthquake, and performed a thematic analysis of the data. …”
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Thai Guideline for Nuclear Medicine Investigations of Neurocognitive Disorders: Nuclear Medicine Society of Thailand, the Neurological Society of Thailand, and Thai Medical Physici... by Tawika Kaewchur, Tanyaluck Thientunyakit, Wichana Chamroonrat, Benjapa Khiewvan, Peerapon Kiatkittikul, Nantaporn Wongsurawat, Chanisa Chotipanich, Yuttachai Likitjaroen, Vorapun Senanarong, Panya Pasawang, Tanawat Sontrapornpol, Nucharee Poon-iad, Sasithorn Amnuaywattakorn, Supatporn Tepmongkol

“…By providing functional and molecular data via brain imaging, nuclear medicine investigations offer valuable insights that complement clinical evaluations and structural imaging in the early detection, diagnosis, and differentiation of various types of dementia, leading to more accurate diagnosis and personalized treatment planning. …”
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Telemedicine for under-resourced patients with systemic lupus erythematosus: a qualitative study exploring the views and experiences of patients and their healthcare team by Savannah Bowman, Sandeep K. Agarwal, Keshia C. Ferguson, Maryjo J. Maliekel, Maria A. Lopez-Olivo, Maria E. Suarez-Almazor, Maria I. Danila, Maria I. Danila, Jinoos Yazdany, Sebastian Bruera

“…Using Levesque's conceptual framework for healthcare access, semi-structured interviews and content analysis were used to explore benefits and limitations of telemedicine in under-resourced patients with SLE. …”
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Lived Experiences of Sexual and Gender Minorities in Solid Organ Transplantation: A Best-Fit Framework Synthesis and Inductive Thematic Analysis by Murdoch Leeies, Carmen Hrymak, David Collister, Emily Christie, Karen Doucette, Ogai Sherzoi, Tricia Carta, Ken Sutha, Cameron T. Whitley, Tzu-Hao Lee, Matthew J. Weiss, Sonny Dhanani, Julie Ho

“…Targets for improvement included (1) enhancements to shared decision-making between OTDT providers and patients, (2) transparent communication from OTDT organizations, (3) data-driven donor risk assessments, (4) expanded healthcare worker training, (5) inclusive physical care spaces, (6) recommendations for transgender and gender-diverse health system planning, (7) integrated sexual and reproductive healthcare services for transplant recipients, (8) increased SGM representation in medical education and care settings, (9) SGM and OTDT intersectional support networks, and (10) structural facilitation of SGM community advocacy efforts. …”
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Working memory related functional connectivity in adult ADHD and its amenability to training: A randomized controlled trial by Tuija Tolonen, Sami Leppämäki, Timo Roine, Kimmo Alho, Pekka Tani, Anniina Koski, Matti Laine, Juha Salmi

“…WM training did not modulate functional or structural connectivity compared with the active controls. …”
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Isolated Rapid Deployment Aortic Valve Replacement in Patients with Aortic Stenosis: Single-Center Retrospective Study by Ricardo Ferreira, Tiago R. Velho, João Gonçalves, André Sena, Beatriz Draiblate, Ana G. Almeida, Ângelo Nobre, Fausto Pinto

“…At a median follow-up of 6.7 years, no cases of structural valve deterioration and only one case of endocarditis were reported. …”
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Decreasing prevalence of anaemia in pregnant women at delivery: a quality improvement initiative by Vidushi Kulshrestha, K Aparna Sharma, Neena Malhotra, Anushka Rathi, Swati Sharma, Tanisha Gupta, Aditya Sarkar, Srinidhi Y Reddy, Nambrath Sunita, Joby Titto

“…At AIIMS, New Delhi, baseline data revealed a 35.57% prevalence of anaemia among booked pregnant women at delivery. …”
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Long COVID and episodic disability: advancing the conceptualisation, measurement and knowledge of episodic disability among people living with Long COVID – protocol for a mixed-met... by Richard Harding, Kristine M Erlandson, Jaime H Vera, Colm Bergin, Ciaran Bannan, Darren A Brown, Margaret O'Hara, Kelly K O'Brien, Patricia Solomon, Angela M Cheung, Lisa Avery, Soo Chan Carusone, Susie Goulding, Lisa McCorkell, Larry Robinson, Catherine Thomson, Hannah Wei, Natalie St Clair-Sullivan, Brittany Torres, Niamh Roche, Ruth Stokes, Patriic Gayle

“…Using phase 2 data, we will characterise the profile of disability using structural equation modelling techniques to examine relationships between dimensions of disability and the influence of intrinsic and extrinsic contextual factors. …”
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Real-Time FTM-Based Victim Positioning System Using Heterogeneous Robots in Remote and Outdoor Scenarios by Juan Bravo-Arrabal, Carlos Simon Alvarez-Merino, Manuel Toscano-Moreno, Javier Seron-Barba, J. J. Fernandez-Lozano, Jose Antonio Gomez-Ruiz, Emil J. Khatib, Raquel Barco, Alfonso Garcia-Cerezo

“…A centralized Feedback Information System (FIS) processes real-time RTT data from the field, executes a multilateration algorithm, and provides live geolocation updates to SAR coordinators. …”
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Top 10 palliative care research priorities in France: a 3-step, mixed-methods protocol (AXEPRO study) by Stéphane Sanchez, Guillaume Economos, Fiona Ecarnot, Cecile Barbaret, Raphaëlle Habert-Dantigny, Héloïse Rouze, Doan Huynh, Roseline Huynh, Caroline Tête, Martin Julier-Costes, Valérie Amouroux-Gorsse, Isabelle Lavault, Justine Bret

“…A multidisciplinary steering committee including board-certified PC physicians, methodologists, nurses, a sociologist, an anthropologist and an information specialist will analyse the data collected in order to delete duplicate questions, do a thematic and population classification of the responses, modify questions using the PICO (patient problem, intervention, comparison and outcome) format and perform a literature review on each question to identify any relevant systematic review.Ethics and dissemination We expect the results to have wide-ranging benefits, for example, by prompting investment in the 10 prioritised research questions. …”
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From reality to virtuality: Unveiling Gen Z's purchasing behavior through virtual influencers in the metaverse by Tri-Quan Dang, Tan-Minh Nguyen, Phuc-Thien Tran, Tien-Thao Cong Phan, Thach-Bao Huynh, Luan-Thanh Nguyen

“…Utilizing judgmental sampling, a sample of 352 individuals with prior experience as VIs was selected to address the research objectives. The data were analyzed using a mixed-method approach, incorporating fuzzy-set Qualitative Comparative Analysis (fsQCA), Partial Least Squares Structural Equation Modeling (PLS-SEM), and Artificial Neural Networks (ANN techniques). …”
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ARTISANAL FISHING ON THE COAST OF ESPÍRITO SANTO STATE, SOUTHEASTERN BRAZIL: AN APPROACH TO SOCIOENVIRONMENTAL OCEANOGRAPHY by Joelson MUSIELLO-FERNANDES, Pablo da Costa OLIVEIRA, Samanta Chisté de ARAÚJO, Juliana Silva de ABREU, Ana Paula Madeira DI BENEDITTO, Adriane Araújo BRAGA, Mauricio HOSTIM-SILVA, Camilah Antunes ZAPPES

“…Despite this, there is a lack of updated data on artisanal fishing and its interfaces with socioenvironmental oceanography. …”
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Identification of multiple genomic alterations and prediction of neoantigens from circulating tumor cells at the single-cell level by Xiaochen Gao, Xinyu Li, Weize Xu, Ming Jiao, Yu Guo, Jiajia Wang, Weihao Wang, Jiling Feng, Qianqian Guo, Chengchao Wu, Taiyu Zhang, Yuqin Yang, Da Lin

“…In the PDX model, integrating data from seven CTCs captures 88.7% of SNPs and INDELs, and 75.0% of structural variants present in tumor tissue. …”
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Tackling Paradoxes and Double Binds for a Healthier Workplace: Insights from the Early COVID-19 Responses in Quebec and Ontario by Daniel Côté, Amelia León, Ai-Thuy Huynh, Jessica Dubé, Ellen MacEachen, Pamela Hopwood, Marie Laberge, Samantha Meyer, Shannon Majowicz, Meghan K. Crouch, Joyceline Amoako

“…This study presents a secondary analysis of qualitative data on paradoxes and double binds (PDBs) experienced by precarious essential workers in Canada who interacted with the public and their supervisors. …”
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Prevalence and environmental abundance of the TSET complex in cosmopolitan algal groups by Mathias Penot-Raquin, Mandeep Sivia, Kelly M. Fafoumi, Raegan Larson, Richard G. Dorrell, Joel B. Dacks

“…Finally, diatom TSET genes are detectable in meta-transcriptomic data from Tara Oceans, suggesting functional roles in the wild. …”
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