Leveraging AI to explore structural contexts of post-translational modifications in drug binding by Kirill E. Medvedev, R. Dustin Schaeffer, Nick V. Grishin

“…Recent advancements in computational power and artificial intelligence, particularly in deep learning algorithms and protein structure prediction tools like AlphaFold3, have opened new possibilities for exploring the structural context of interactions between PTMs and drugs. …”
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Structural and Dynamical Effects of the CaO/SrO Substitution in Bioactive Glasses by Margit Fabian, Matthew Krzystyniak, Atul Khanna, Zsolt Kovacs

“…Motivated by these recent developments, the effect of SrO/CaO–CaO/SrO substitution on the local structure and dynamics of Si-Na-P-Ca-O oxide glasses has been studied in this work. …”
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Determinants of child malnutrition and morbidity in Ethiopia: a structural equation modeling approach by Birhanu Betela Warssamo, Denekew Bitew Belay, Denekew Bitew Belay, Ding-Geng Chen, Ding-Geng Chen

“…Thus, this study aims to investigate the underlying risk factors by employing a structural equation model to analyze malnutrition as a mediator in the relationship between selected factors and morbidity.MethodsThe study utilized data from the 2016 Ethiopia Demographic and Health Survey and a sample of 8,560 under-five children were considered. …”
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The effect of conservation in various cryoprotectants on the properties and morphological structure of the umbilical cord arteries by V. A. Brumberg, T. A. Astrelina, T. F. Malivanova, I. V. Kobzeva, Yu. B. Suchkova, V. A. Nikitina, D. Yu. Usupzhanova, V. A. Brunchukov, S. V. Lishchuk, P. S. Kyzlasov, A. A. Kazhera, V. M. Troyakov, A. S. Samoilov

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The Temporal Structure of the Running Cycle, an Essential Element in the Analysis: A Critical Review by Felipe Inostroza-Ríos, Pablo Merino-Muñoz, Celso Sánchez-Ramírez, Alejandro Bustamante Garrido, Jorge Pérez-Contreras, Jorge Cancino-Jimenez, David Arriagada-Tarifeño, Esteban Aedo-Muñoz, Ciro José Brito

“…Additionally, methodologies for identifying these events through dynamometry and motion capture are evaluated, emphasizing their role in contextualizing kinetic and kinematic data. By integrating this temporal structure, the study aims to standardize biomechanical assessments of running technique, fostering more consistent comparisons across studies. …”
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Choroid plexus aging: structural and vascular insights from the HCP-aging dataset by Zhe Sun, Chenyang Li, Jiangyang Zhang, Thomas Wisniewski, Yulin Ge

“…Abstract Background The choroid plexus (ChP), a highly vascularized structure within the ventricles, is essential for cerebrospinal fluid (CSF) production and metabolic waste clearance, crucial for neurofluid homeostasis and cognitive function. …”
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High Resolution Mass Spectrometry Fragmentation Rules of Etomidate and Its Structural Analogues by FAN Xian-yu, ZHU Xue-yan, WANG Xin, XIANG Ping, ZHAO Jun-bo

“…ObjectiveTo explore the characteristic fragment ions, ion abundance ratios and mass spectrometry fragmentation rules of etomidate and its structural analogues by using gas chromatography-quadrupole/orbitrap mass spectrometry （GC-Q/Orbitrap MS） and liquid chromatography-linear ion trap quadrupole-orbitrap mass spectrometry （LC-LTQ-Orbitrap MS） techniques, providing important data support for the identification and prediction of etomidate structural analogues.MethodsGC-Q/Orbitrap MS and LC-LTQ-Orbitrap MS were used to analyze metomidate, etomidate, isopropoxate and propoxate, to obtain their GC high resolution mass spectra and LC high resolution mass spectra.ResultsUnder the electron impact （EI） ion source mode, etomidate, metomidate and the other two analogues all produced their molecular ions and seven identical fragment ions （m/z 77.038 6, 79.054 2, 95.024 0, 105.069 9, 143.073 0, 172.099 5 and 199.086 6）, among which isopropoxate and propoxate also produced characteristic fragment ions m/z 216.089 3. …”
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Fine Structure of Glycosaminoglycans from Fresh and Decellularized Porcine Cardiac Valves and Pericardium by Antonio Cigliano, Alessandro Gandaglia, Antonio Junior Lepedda, Elisabetta Zinellu, Filippo Naso, Alessandra Gastaldello, Paola Aguiari, Pierina De Muro, Gino Gerosa, Michele Spina, Marilena Formato

“…Cardiac valves are dynamic structures, exhibiting a highly specialized architecture consisting of cells and extracellular matrix with a relevant proteoglycan and glycosaminoglycan content, collagen and elastic fibers. …”
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Modeling factors related to earthquake preparedness: a structural equation modeling approach by Azadeh Fatehpanah, Elham Maraghi, Anthony Coetzer-Liversage, Mahmood Karimy, Amir H. Pakpour, Majed Maripour, Nematollah Jaafarzadeh Haghighi Fard, Marzieh Araban

“…Structural equation modeling (SEM) was employed to analyze TPB constructs, including attitudes, subjective norms, perceived behavioral control, and intentions, in relation to earthquake preparedness behaviors. …”
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L-Ornithine derivatives with structural hetaryl and alkyl moiety: Synthesis and antibacterial activity by T. G. Bodrova, U. A. Budanova, Yu. L. Sebyakin

“…Nine new lipoamino acid cationic bivalent amphiphiles based on L-ornithine were synthesized. The structure of the obtained compounds was confirmed by nuclear magnetic resonance 1H spectroscopy and mass spectrometry data. …”
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Tau follows principal axes of functional and structural brain organization in Alzheimer’s disease by Julie Ottoy, Min Su Kang, Jazlynn Xiu Min Tan, Lyndon Boone, Reinder Vos de Wael, Bo-yong Park, Gleb Bezgin, Firoza Z. Lussier, Tharick A. Pascoal, Nesrine Rahmouni, Jenna Stevenson, Jaime Fernandez Arias, Joseph Therriault, Seok-Jun Hong, Bojana Stefanovic, JoAnne McLaurin, Jean-Paul Soucy, Serge Gauthier, Boris C. Bernhardt, Sandra E. Black, Pedro Rosa-Neto, Maged Goubran

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Change in Organizational Structure Influences Perceived Leadership in a Dutch Radiotherapy Center by Swart RR, Jacobs MJ, Van Merode F, Boersma LJ

“…This study examines the impact of structural changes on perceived leadership styles in a Dutch radiotherapy center (RTc) following the implementation of proton therapy, a radical innovation.Patients and Methods: A mixed-method approach combined leadership surveys, with data collected at three time points, before and after structural changes in 2022. …”
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Cancer pain and quality of life structural equation model based on the biopsychosocial model by Xiaoyu Hu, Jingjing Lü, Chang Qin, Xiaoxuan Liu, Jianbiao Zhu, Yongchun Cui

“…Abstract Objective This study employed a biopsychosocial framework to develop structural equation models(SEM)quantifying the multidimensional impact of pain on quality of life in cancer patients, aiming to provide scientific evidence and novel clinical perspectives for evidence-based pain management strategies. …”
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Modelling and optimisation of the structural performance of lightweight polypropylene fibre-reinforced LECA concrete by Idris Ahmed Ja'e, Zakaria Che Muda, Mugahed Amran, Agusril Syamsir, Chiemela Victor Amaechi, Ebrahim Hamid Hussein Al-Qadami, Marco Antonio Díaz Huenchuan, Siva Avudaiappan

“…However, achieving an optimal balance between structural weight, and performance remains a challenging endeavour. …”
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Monitoring of the assortment structure and price dynamics of hepatoprotectors in the modern Ukrainian pharmaceutical market by I. O. Pukhalska, Аdaba Мukhamed, О. P. Hudzenko, О. L. Drozdov

“…During investigation, systemic, structural, logical practices and method of summarization were used. …”
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STRUCTURAL FEATURES OF PURULENT INFLAMMATORY DISEASES OF THE MAXILLOFACIAL REGION IN RESIDENTS OF THE POLTAVA REGION by D.V. Steblovskyi, M.G. Skikevich, V.V. Bondarenko

“…The aim of the study. Investigate the structure and frequency of purulent inflammatory diseases in residents of Poltava region. …”
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Gender prevalence and pattern structure of various online behaviors among adolescents in Abakan by L. S. Evert, S. Yu. Tereshchenko, Yu. R. Kostyuchenko, N. B. Semenova

“…The aim of the study was to research the gender prevalence and pattern structure of various types of online behavior in adolescents from Abakan (Khakassia). …”
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Evaluating the effects of coffee consumption on the structure and function of the heart from multiple perspectives by Xiong-Bin Ma, Yan-Lin Lv, Lin Qian, Jing-Fen Yang, Qian Song, Yong-Ming Liu

“…ObjectiveTo assess the causal relationship between coffee consumption and cardiac structure and function in elderly European populations using multiple genetic methodologies.MethodsLeveraging genome-wide association study (GWAS) data from elderly European populations, we conducted linkage disequilibrium score regression (LDSC), two-step Mendelian randomization (MR), and colocalization analyses to investigate genetic associations, causal relationships, and mediating effects among these factors. …”
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THE PALEOPROTEROZOIC IMANDRA-VARZUGA RIFTING STRUCTURE (KOLA PENINSULA): INTRUSIVE MAGMATISM AND MINERAGENY by V. V. Chashchin, F. P. Mitrofanov

“…The article provides data on the structure of the Paleoproterozoic intercontinental Imandra-Varzuga rifting structure (IVS) and compositions of intrusive formations typical of the early stage of the IVS development and associated mineral resources. …”
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Structural Geomorphology and Tectonic Dynamism of the Lolodorf Segment, Nyong Complex, SW Cameroon by Messi Ottou Eric José, Etoundi Akoa Philémon Rémi, Ntieche Benjamin, Ntomba Sylvestre Martial, Evina Aboula Yannick Saturnin, Ndjigui Paul-Désiré

“… The study of the structural geomorphology and tectonic dynamism of the Lokoundjé and Nyong watersheds has made possible to discriminate the essential geological objects of the Lolodorf region (3°10’- 3°25’N, 10°40’- 10°55’E), in Southern Cameroon. …”
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