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3421
Considerations for Establishing a Behavioral Policy-Making and Nudge Institution within the Country's Executive Structure
Published 2024-11-01“…Through this rigorous interview process, a wealth of qualitative data was gathered to assess both the potential and the challenges associated with forming a dedicated behavioral insight institution.ResultsThe literature review summarizes the experiences of countries with behavioral insight teams, presenting them in three areas: operational goals and tasks, institutional and organizational structure, and legal frameworks. …”
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3422
The structure of an amyloid precursor protein/talin complex indicates a mechanical basis of Alzheimer’s disease
Published 2024-11-01“…Here, we report the crystal structure of an APP/talin1 complex identifying a new way to couple the cytoskeletal machinery to synaptic sites through APP. …”
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3423
Tracing the aggregation pathway of the scaffold protein DISC1: Structural implications for chronic mental illnesses
Published 2025-06-01“…Disrupted in schizophrenia 1 (DISC1) is a pleiotropic scaffold protein that is postulated to comprise large disordered regions and four distinct structured segments with a high proportion of helical or coiled-coil fold. …”
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3424
Development and distribution characteristics of geohazards based on sedimentary-structural evolution in Xide County, southwest Sichuan
Published 2025-05-01“…The wide and gentle fold structures in red beds are the disaster-prone environment for landslide. …”
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3425
Comparative Whole-Genome Analysis of Production Traits and Genetic Structure in Baiyu and Chuanzhong Black Goats
Published 2024-12-01“…Furthermore, we conducted a comprehensive analysis of genetic diversity, population structure, and selection signatures using whole-genome resequencing data. …”
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3426
Genomic structural equation modeling reveals latent phenotypes in the human cortex with distinct genetic architecture
Published 2024-10-01“…Even though we observed model instability in our application of genomic SEM to high-dimensional data, jointly modeling the genetic architecture of complex traits and investigating multivariate genetic links across neuroimaging phenotypes offers new insights into the genetics of cortical structure and relationships to psychopathology.…”
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3427
Presence of Pain Shows Greater Effect than Tendon Structural Alignment During Landing Dynamics
Published 2025-02-01“…This study aims to investigate the relationship between tendon structure, presence of pain, and sex differences in landing kinematics and kinetics during countermovement jumps (CMJ) and tuck jump tests (TJT) in professional volleyball players. …”
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3428
Structural placental changes in women with intra-pregnancy novel coronavirus infection COVID-19 (review)
Published 2023-01-01“…In those that were excluded from the review, information about the clinical course of pregnancy and its outcome during novel coronavirus infection prevailed, or isolated cases of studying insignificant placental structural changes were discussed. Studies with a small number of observations were selected only in the case of the uniqueness of the published data, the absence of scientific papers where similar studies would have been conducted in larger sample.Results. …”
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3429
Impact of the fishing ban on fish diversity and population structure in the middle reaches of the Yangtze River, China
Published 2025-01-01“…Fish monitoring data collected from 2017–2019 (pre-ban) and 2021–2023 (post-ban) were analyzed to evaluate changes in fish body size, species diversity, and community structure. …”
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3430
The structural and functional brain alternations in tobacco use disorder: a systematic review and meta-analysis
Published 2025-04-01“…Consequently, it is important to utilize relevant coordinate data for a comprehensive meta-analysis to identify the shared patterns of structural, functional, and multimodal alternations in TUD.MethodThe present study conducted a systematic retrieval of studies published on PubMed, Web of Science, and Scopus from January 1, 2010, to December 12, 2023, to identify studies on voxel-based morphometry (VBM) and resting-state functional magnetic resonance imaging (rs-fMRI) for TUD. …”
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3431
Investigating the Relationship between Financialization and Long-Term Use of Short-Term Debt
Published 2025-09-01“…It provides empirical evidence at the firm level and investigates the underlying mechanisms through which financialization influences the long-term use of short-term debt.Keywords: Capital Structure, Debt Maturity Structure, Financialization, Tangible Long-Term InvestmentsJEL Classification: G11، G31، P45 IntroductionAccording to the principle of matching investment and financing maturities, the maturity of a firm's debt should correspond to the maturity of its assets (Chen et al., 2023). …”
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3432
Divergent trajectories to structural diversity impact patient survival in high grade serous ovarian cancer
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3433
Pharmacological and structural characterization of vibostolimab, a novel anti-TIGIT blocking antibody for cancer immunotherapy
Published 2025-08-01“…The mouse surrogate anti-TIGIT antibodies were identified and used to extensively investigate the mechanism of action of anti-TIGIT antibodies as monotherapy or in combination with anti-programmed cell death protein-1 (PD-1) antibody in vivo by gene expression profiling and flow cytometry analyses with a mouse syngeneic tumor model.Results Structural analyses with solution NMR and X-ray crystallography revealed that vibostolimab binds the CC’C’’FG loop interface of TIGIT, completely competing for the binding site of CD155 with a larger coverage area than another anti-TIGIT antibody tiragolumab, consistent with surface plasmon resonance analysis, though mouse models with similar antibodies revealed no functional difference in antitumor efficacy. …”
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3434
Explaining the Effects of Geotourism on the Development of Entrepreneurship in City- Village Ghori-Ghalhe with Structural Equation Approach
Published 2017-05-01“…Finally, the results of final model of fitted structural equation for geotourism effect (as the independent variable of studdy) on entrepreneurship development (as dependent variable) among households of QuriQalhe showed that geotourism, at a confidence level of 99%, has a significant effect on the development of entrepreneurship and its indicators. …”
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3435
Parcel-scale crop planting structure extraction combining time-series of Sentinel-1 and Sentinel-2 data based on a semantic edge-aware multi-task neural network
Published 2025-08-01“…Ultimately, a parcel-scale random forest (RF) model was developed to enable accurate crop type classification and spatial delineation of crop planting structures. Results show: 1) SEANet achieves accurate extraction of parcel boundaries, extracting a total of 175,000 parcels, and demonstrates a relative error of 6.98% compared to statistical yearbook data. …”
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3436
Optimisation of the performance and structure of soluble ball seat metal sealing rings based on response surface
Published 2025-01-01“…On this basis, the Box-Behnken design is used to construct a four-factor and three-level experimental scheme, and a second-order response surface agent model is established by 25 sets of simulation data, with the dual optimization objectives of minimizing the equivalent force and maximizing the contact pressure, and the relationship between the structural parameters and the equivalent force and the contact pressure as the optimization function, and the range of geometrical parameters as the boundary conditions. …”
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3437
Characteristics of demersal fish community structure during summer hypoxia in the Pearl River Estuary, China
Published 2024-07-01“…Further analysis demonstrated that dissolved oxygen had a significantly stronger effect on fish community structure at hypoxic sites than in the whole PRE. Moreover, other environmental variables also had significant effects on the fish community structure and interacted with dissolved oxygen in the hypoxia area. …”
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3438
Seismic Mitigation Performance and Damage of Prefabricated Base Isolation Structure Based on the Shaking Table Test
Published 2025-01-01“…Secondly, Shaking table tests were conducted on the prefabricated base isolation structural model. And acceleration sensors and laser displacement transducers were installed on the test specimen to collect dynamic response data. …”
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3439
A whole-brain voxel-based analysis of structural abnormalities in PTSD: An ENIGMA-PGC study
Published 2025-01-01“…In the current study, we have conducted a voxel-based morphometry (VBM) meta-analysis using whole-brain statistical maps with neuroimaging data from the ENIGMA-PGC PTSD working group. Methods T1-weighted structural neuroimaging scans from 36 cohorts (PTSD n = 1309; controls n = 2198) were processed using a standardized VBM pipeline (ENIGMA-VBM tool). …”
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3440
2-Amino-4-ferrocenyl-5-oxo-5,6,7,8-tetrahydro-4H-chromene-3-carbonitrile monohydrate
Published 2025-05-01Get full text
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