In Vitro Structure–Activity Relationship Stability Study of Antisense Oligonucleotide Therapeutics Using Biological Matrices and Nucleases by Jelena Lovrić, Jingjing Yan, XueQing Li, Tony Karlsborn, Mattias Bood, Anders Dahlén, Constanze Hilgendorf, Deepak Kumar Bhatt

Get full text

Potential compensatory mechanism for cognitive impairment in type 2 diabetes and prediabetes: altered structure-function coupling by Weiye Lu, Xuan Huang, Die Shen, Kun Wang, Jiahe Wang, Ziyu Diao, Shijun Qiu, Shijun Qiu

“…BackgroundStructure-function (SC-FC) coupling may be more sensitive to detecting changes in the brain than any single modality. …”
Get full text

Impact of a Structured Social Skills Training Program on Adolescents and Young Adults with Level 1 Autism by Leonardo Zoccante, Sara Sabaini, Erika Rigotti, Sophia Marlene Bonatti, Camilla Lintas, Marco Zaffanello

“…This study aims to evaluate the effectiveness of a structured social skills training programme for adolescents and young adults with level 1 ASD. …”
Get full text

HPV16 genome structure analysis in oropharyngeal cancer PDXs identifies tumors with integrated and episomal genomes by Claire D. James, Raymonde O. Otoa, Aya H. Youssef, Christian T. Fontan, Malay K. Sannigrahi, Brad Windle, Devraj Basu, Iain M. Morgan

“…Here we characterize HPV genome structures in eight HPV16+ OPC patient-derived xenografts (PDXs), and evaluate their responses to standard chemotherapy. …”
Get full text

Is AI the future of evaluation in medical education?? AI vs. human evaluation in objective structured clinical examination by Murat Tekin, Mustafa Onur Yurdal, Çetin Toraman, Güneş Korkmaz, İbrahim Uysal

“…Abstract Background Objective Structured Clinical Examinations (OSCEs) are widely used in medical education to assess students’ clinical and professional skills. …”
Get full text

Fine Scale Patterns of Population Structure and Connectivity in Scandinavian Flat Oysters in Scandinavia (Ostrea edulis L.) by Chloé Robert, Homère J. Alves Monteiro, Alan Le Moan, Arnaud Tanguy, Ane T. Laugen, Jakob Hemmer‐Hansen, Åsa Strand, Pierre De Wit

“…However, despite recent studies focusing on flat oyster population structure along the European coast, little is known about the population structure of oysters in the Skagerrak marginal sea in Scandinavia, and how it is related to neighbouring regions. …”
Get full text

Diabetes care in the pandemic era in the Midwestern USA: a semi-structured interview study of the patient perspective by Shakoora A Sabree, Kimberly Dukes, Carolina Gonzalez Bravo, Morolake J Adeagbo, Sarai Edwards, Kasey Wainwright, Sienna E Schaeffer, Aneli Villa, Aloha D Wilks, Martha L Carvour

“…Objectives To understand patients’ experiences with diabetes care during the COVID-19 pandemic, with an emphasis on rural, medically underserved, and/or minoritised racial and ethnic groups in the Midwestern USA.Design Community-engaged, semi-structured interviews were conducted by medical student researchers trained in qualitative interviewing. …”
Get full text

Temporal trends of blood-based markers in various psychiatric disorders and their cross-sectional brain structure associations by Yu-Jia Wang, Zairen Zhou, Yu-Zhu Li, Ju-Jiao Kang, Jin-Tai Yu, Jian-Feng Feng, Wei Cheng, Guoqing Pan, Jia You, Linbo Wang

“…This study aimed to explore these trends in the decade before and after diagnosis, along with the cross-sectional relationships with brain structures. Methods: Utilizing UK Biobank data, we conducted a nested case-control analysis of individuals aged 40-69 years diagnosed with anxiety (n = 27,216), bipolar disorder (n = 1325), depression (n = 36,570), or schizophrenia (n = 1478) within 10 years of baseline. …”
Get full text

Cardiac structure and function in anabolic-androgenic steroid users: a 16-year follow-up study by Sigrun Halvorsen, Dan Atar, Anne Rossebø, Tea Sætereng Fyksen, Jørgen Gravning, Paul Vanberg, Ole Jørgen Grøtta

“…Background and aim Long-term data on cardiac changes in anabolic-androgenic steroid (AAS) users are lacking. …”
Get full text

EFFECT OF ARGININE DEIMINASE FROM STREPTOCOCCUS PYOGENES ON CYTOSKELETON STRUCTURE AND MIGRATION ACTIVITY OF HUMAN ENDOTHELIAL CELLS by E. A. Starikova, J. T. Mammedova, L. A. Burova, A. V. Sokolov, V. B. Vasilyev, I. S. Freidlin

“…To analyze the influence of bacterial factors on the actin cytoskeleton structure, cells were stained with phalloidin-rhodamine. …”
Get full text

THE FIRST EXPERIENCE IN DIAGNOSING THE GEODYNAMIC MECHANISMS OF FOLDING BY THE FACTOR ANALYSIS OF FOLDED STRUCTURE PARAMETERS (GREATER CAUCASUS) by F. L. Yakovlev, E. S. Gorbatov

“…A specific feature of our study is statistical analysis of the data obtained by the methods of tectonophysics and structural geology. …”
Get full text

FARM STRUCTURE AND FARMLAND CONCENTRATION IN ROMANIA AND IN OTHER SELECTED EU'S COUNTRIES WITH LARGE UTILIZED AGRICULTURAL AREA by Agatha POPESCU

“…Fixed basis indices, regression equations, R square, Herfindahl-Hirschman Index (HHI), Gini Struck Coefficient(GSC), structural indices, comparisons with the EU average and among the selected EU countries: Romania, Poland, Italy, Spain, France, Germany, United Kingdom were used as processing methods for reflecting the changes farmland and farm structures. …”
Get full text

The natural diet composition of young piglets suggests an overlook of fibre and food structure in farmed suckling piglets by Renjie Yao, Hubèrt M. J. van Hees, An Cools, Sebastián A. Ballari, Dominiek Maes, Geert P. J. Janssens

Get full text

Global stock structure of the Silky shark (Carcharhinus falciformis, Carcharhinidae) assessed with high-throughput DNA sequencing by Derek W. Kraft, Emily E. Conklin, Evan B. Freel, Melanie Hutchinson, Julia L.Y. Spaet, Robert J. Toonen, Zac H. Forsman, Michael I. Grant, John David Filmalter, John R. Hyde, Simon J.B. Gulak, Brian W. Bowen

“…Here we investigate the global stock structure of silky sharks and compare population structure to the four RFMO boundaries. …”
Get full text

Perfluorohexane Sulfonic Acid Disrupts the Immune Microenvironment for Spermatogenesis by Damaging the Structure of the Blood‐Testis Barrier in Mice by Yan Zhang, Mingxue Shu, Shilin Shan, Huiying Liu, Yucheng Zhang, Chenyang Song, Qiaoqiao Xu, Yun Fan, Chuncheng Lu

“…Additionally, it is found that the structure of the blood‐testis barrier (BTB) is damaged after PFHxS treatment, leading to higher expression levels of inflammatory cytokines in the microenvironment for spermatogenesis. …”
Get full text

Velocity Structure Correlations between the Nebular, Molecular, and Atmospheric Gases in the Cores of Four Cool Core Clusters by Muzi Li, B.R. McNamara, Alison L. Coil, Marie-Joëlle Gingras, Fabrizio Brighenti, H.R. Russell, Prathamesh D. Tamhaneh, S. Peng Oh, Serena Perrotta

“…We investigate the velocity structure of nebular gas in the central galaxies of four clusters: A1835, PKS 0745−191, A262, and RXJ0820.9+0752, using data from the Keck Cosmic Web Imager. …”
Get full text

Multi-level Hierarchical Structure Analysis of Influencing Factors of Coal Mine Managers' Blame Avoidance Behavior by Li Wang, Wenyi Zeng, Ziyan Jing, Yonghui Xu, Jiang Li

“…Methods: Based on the semi-structured interviews and questionnaire surveys (20 middle-level managers in coal mines), this paper used the Grounded Theory and Nvivo Software qualitative research methodology to open, spindle, and selectively encode the interview data. …”
Get full text

Advancing macromolecular structure determination with microsecond X-ray pulses at a 4th generation synchrotron by Julien Orlans, Samuel L. Rose, Gavin Ferguson, Marcus Oscarsson, Alejandro Homs Puron, Antonia Beteva, Samuel Debionne, Pascal Theveneau, Nicolas Coquelle, Jerome Kieffer, Paolo Busca, Jeremy Sinoir, Victor Armijo, Marcos Lopez Marrero, Franck Felisaz, Gergely Papp, Herve Gonzalez, Hugo Caserotto, Fabien Dobias, Jonathan Gigmes, Guillaume Lebon, Shibom Basu, Daniele de Sanctis

“…Abstract Serial macromolecular crystallography has become a powerful method to reveal room temperature structures of biological macromolecules and perform time-resolved studies. …”
Get full text

Sugarcane bagasse derived biochar potential to improve soil structure and water availability in texturally different soils by Farzad Moradi-Choghamarani, Ali Akbar Moosavi, Ali Reza Sepaskhah

“…The high energy moisture characteristic (HEMC) data was modeled using a modified van Genuchten function to quantify aggregate stability through stability ratio (SR) and structural stability index (SSI). …”
Get full text

Investigating tree diversity and structure across varying land cover classes and altitudes in the savanna woodlands of Sudan by Nasradeen A. H. Gadallah, Nasradeen A. H. Gadallah, Nasradeen A. H. Gadallah, Zoro Bertin Gone Bi, Zoro Bertin Gone Bi, Victor Ongoma, Ali Omer, Ali Omer, Abdelhakam Esmaeil Mohamed Ahmed, Abdelhakam Esmaeil Mohamed Ahmed, Ahmed M. M. Hasoba, Ahmed M. M. Hasoba, Ahmed A. H. Siddig, Ahmed A. H. Siddig

“…A systematic sampling was used across varying AGs and LC types to collect data on tree species richness and structure in 926 circular plots. …”
Get full text