Cavin-3 knockout mice show that cavin-3 is not essential for caveolae formation, for maintenance of body composition, or for glucose tolerance. by Libin Liu, Carsten G Hansen, Brian J Honeyman, Benjamin J Nichols, Paul F Pilch

“…Likewise, the two mouse strains exhibit identical glucose tolerance tests on both diets. Microarray analysis from adipose tissue shows that the changes in mRNA expression between cavin-3 null and wild type mouse are minimal. …”
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Assessment of Human Epididymis Protein 4 Expression in Breast Ductal Carcinoma In Situ by Nah Ihm Kim, Min Ho Park, Ji Shin Lee

“…An additional independent tissue microarray of 41 DCIS cases was also analyzed for HE4 expression in tumor tissue only. …”
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Altered Expression Profile of Renal α1D-Adrenergic Receptor in Diabetes and Its Modulation by PPAR Agonists by Xueying Zhao, Yuanyuan Zhang, Michelle Leander, Lingyun Li, Guoshen Wang, Nerimiah Emmett

“…The present study was designed to investigate the expression profile of α1D-AR in the diabetic kidneys and its modulation by activation of peroxisome proliferator-activated receptors (PPARs). 12-week-old Zucker lean (ZL) and Zucker diabetic fatty (ZD) rats were treated with fenofibrate or rosiglitazone for 8–10 weeks. Gene microarray, real-time PCR, and confocal immunofluorescence microscopy were performed to assess mRNA and protein expression of α1D-AR in rat kidney tissue. …”
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Transcriptomic Profiling of Virus-Host Cell Interactions following Chicken Anaemia Virus (CAV) Infection in an In Vivo Model. by Efstathios S Giotis, Lisa Rothwell, Alistair Scott, Tuanjun Hu, Richard Talbot, Daniel Todd, David W Burt, Elizabeth J Glass, Pete Kaiser

“…There was little evidence of a Th1 adaptive immune response in any lymphoid tissue, as would normally be expected in response to viral infection. …”
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Transcriptional changes during hepatic ischemia-reperfusion in the rat. by Valerie Zabala, Joan M Boylan, Paul Thevenot, Anderson Frank, Dewahar Senthoor, Varun Iyengar, Hannah Kim, Ari Cohen, Philip A Gruppuso, Jennifer A Sanders

“…These tissue autonomous and non-autonomous responses may serve as targets to ameliorate IR injury.…”
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Epigenetic Studies Point to DNA Replication/Repair Genes as a Basis for the Heritable Nature of Long Term Complications in Diabetes by Alexey A. Leontovich, Robert V. Intine, Michael P. Sarras

“…In the current study, control, DM, and MM excised fin tissues were further analyzed by MeDIP sequencing and microarray techniques. …”
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Engineering glycosyltransferases into glycan binding proteins using a mammalian surface display platform by Ryoma Hombu, Lauren E. Beatty, John Tomaszewski, Sheldon Park, Sriram Neelamegham

“…Spectral flow cytometry and tissue microarray analysis using sCore2 reveal distinct cell- and tissue-specific sialyl core-2 staining patterns in human blood cells and paraffin-embedded tissue sections. …”
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Site-specific expression of amine oxidases in breast cancer metastases by Yoon Jin Cha, Woo Hee Jung, Ja Seung Koo

“…We aimed to evaluate the expression of amine oxidase-related proteins in metastatic breast cancer tissue and determine its clinical implication. A tissue microarray was constructed from a total of 126 metastatic breast tumors (31 bone metastases (24.6%), 36 brain metastases (28.6%), 11 liver metastases (8.7%), and 48 lung metastases (38.1%)). …”
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Pharmacologic inhibition of CSF-1R suppresses intrinsic tumor cell growth in osteosarcoma with CSF-1R overexpression by Cheng Dai, Bin Shen, Shenyan Liu, Cong Li, Shuqun Yang, Jie Wang, Jie Zhang, Manqi Liu, Zhixuan Zhu, Wan Shi, Qi Zhang, Zhui Chen, Nannan Zhang

“…Results IHC analysis of human tissue microarray samples revealed a high prevalence of CSF-1R overexpression in osteosarcoma patient samples. …”
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P67 | EMERGING ROLE OF NUCLEAR PHOSPHOLIPASE C BETA 1 AS POTENTIAL BIOMARKER IN LUNG CANCER

“…PLCβ1 displayed favorable results, therefore its expression was evaluated through immunohistochemistry on a commercial tissue microarray. Notably, the array revealed a consistent nuclear overexpression of the enzyme in tumoral tissue of patients. …”
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Xirp proteins mark injured skeletal muscle in zebrafish. by Cécile Otten, Peter F van der Ven, Ilka Lewrenz, Sandeep Paul, Almut Steinhagen, Elisabeth Busch-Nentwich, Jenny Eichhorst, Burkhard Wiesner, Derek Stemple, Uwe Strähle, Dieter O Fürst, Salim Abdelilah-Seyfried

“…Myocellular regeneration in vertebrates involves the proliferation of activated progenitor or dedifferentiated myogenic cells that have the potential to replenish lost tissue. In comparison little is known about cellular repair mechanisms within myocellular tissue in response to small injuries caused by biomechanical or cellular stress. …”
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Inhibition of dipeptidyl peptidase-4 ameliorates cardiac ischemia and systolic dysfunction by up-regulating the FGF-2/EGR-1 pathway. by Masayoshi Suda, Ippei Shimizu, Yohko Yoshida, Yuka Hayashi, Ryutaro Ikegami, Goro Katsuumi, Takayuki Wakasugi, Yutaka Yoshida, Shujiro Okuda, Tomoyoshi Soga, Tohru Minamino

“…DNA microarray analysis revealed that the cardiac tissue level of early growth response protein 1 (EGR-1), which activates angiogenesis, was significantly reduced in untreated mice with dietary obesity, while this decrease was inhibited by administration of linagliptin. …”
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Gene expression analysis reveals mir-29 as a linker regulatory molecule among rheumatoid arthritis, inflammatory bowel disease, and dementia: Insights from systems biology approach... by Devi Soorya Narayana S, Vino Sundararajan

“…<h4>Methodology</h4>Ten microarray datasets each for RA, and IBD, and nine datasets for dementia were obtained from Gene Expression Omnibus. …”
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Transcription Analysis of the Myometrium of Labouring and Non-Labouring Women. by Gemma C Sharp, James L Hutchinson, Nanette Hibbert, Tom C Freeman, Philippa T K Saunders, Jane E Norman

“…Appropriate analysis of large microarray experiments that compare gene expression in non-labouring and labouring gestational tissues is necessary to help bridge these gaps in our knowledge. …”
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Stroma regulates increased epithelial lateral cell adhesion in 3D culture: a role for actin/cadherin dynamics. by Karen F Chambers, Joanna F Pearson, Naveed Aziz, Peter O'Toole, David Garrod, Shona H Lang

“…<h4>Background</h4>Cell shape and tissue architecture are controlled by changes to junctional proteins and the cytoskeleton. …”
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Aberrant mitochondrial homeostasis at the crossroad of musculoskeletal ageing and non-small cell lung cancer. by Konstantinos Prokopidis, Panagiotis Giannos, Oliver C Witard, Daniel Peckham, Theocharis Ispoglou

“…Screening of the literature resulted in 14 microarray datasets (GSE25941, GSE28392, GSE28422, GSE47881, GSE47969, GSE59880 in musculoskeletal ageing; GSE118370, GSE33532, GSE19804, GSE18842, GSE27262, GSE19188, GSE31210, GSE40791 in NSCLC). …”
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Caveolin-1 in Tumour Cells is Predominately Expressed in the Basal Subtype of Triple-Negative Breast Carcinoma by Savelina Popovska, Ivan Ivanov, Akishi Ooi

“…Triple-negative breast cancer (TNBC) is a subtype of breast cancer which is clinically negative for expression of steroid hormones and HER2 protein. According to DNA microarray profiling, breast cancer was divided into several molecular subgroups, including Luminal A and Luminal B; HER2 overexpressing; normal breast- like and basal-like subtype. …”
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Immunohistochemistry guided segmentation of benign epithelial cells, in situ lesions, and invasive epithelial cells in breast cancer slides. by Maren Høibø, André Pedersen, Vibeke Grotnes Dale, Sissel Marie Berget, Borgny Ytterhus, Cecilia Lindskog, Elisabeth Wik, Lars A Akslen, Ingerid Reinertsen, Erik Smistad, Marit Valla

“…The sections were derived from four breast cancer cohorts. Tissue microarray cores from a fifth cohort of 21 patients was used as a second test set. …”
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Spatially resolved analysis of TGF/BMP signalling in pancreatic ductal adenocarcinoma by digital pathology identifies patient subgroups with adverse outcome by Konstantin Bräutigam, Philipp Zens, Stefan Reinhard, Jessica L. Rohrbach, Simon J. Leedham, Anna S. Wenning, Beat Gloor, Viktor H. Koelzer, Martin Wartenberg

“…Methods We performed a spatially resolved analysis of PDAC on a multi-region tissue microarray cohort of 117 curatively resected PDAC specimens consisting of tumour centre (TC), tumour front (TF), and stromal(-predominant) tissue cores each. …”
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Nanofiber Alignment Regulates NIH3T3 Cell Orientation and Cytoskeletal Gene Expression on Electrospun PCL+Gelatin Nanofibers. by Timothy Fee, Swetha Surianarayanan, Crawford Downs, Yong Zhou, Joel Berry

“…To examine the influence of substrate topology on the behavior of fibroblasts, tissue engineering scaffolds were electrospun from polycaprolactone (PCL) and a blend of PCL and gelatin (PCL+Gel) to produce matrices with both random and aligned nanofibrous orientations. …”
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