The origin recognition complex interacts with a subset of metabolic genes tightly linked to origins of replication. by Erika Shor, Christopher L Warren, Joshua Tietjen, Zhonggang Hou, Ulrika Müller, Ilaria Alborelli, Florence H Gohard, Adrian I Yemm, Lev Borisov, James R Broach, Michael Weinreich, Conrad A Nieduszynski, Aseem Z Ansari, Catherine A Fox

“…Since HMR-E possessed a unique non-replication function, we reasoned that other tight sites might reveal novel functions for ORC on chromosomes. …”
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Effect of Probiotics Complex on Improving Antibiotic-associated Diarrhea in Mice by Liyi LU, Yecheng GAO, Junlong CHEN, Yajuan GUO, Hualin LIU, Chang CHEN, Xinliang MAO

“…Furthermore, the administration of probiotics complex notably up-regulated the mRNA expression levels of intestinal tight junction proteins ZO-1 and occludin (P<0.05). …”
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Comparison between contra-incision combined with high loose-tight thread and traditional incision-thread-drawing procedure for high complex anal fistula by Peng Jue, Peng Yunhua, Liu Suzhi, Chen Tian, Fang Chenyang, Yang Wei

“…[Conclusion] Compared with traditional incision-thread-drawing procedure, contra-incision combined with high loose-tight thread for high complex anal fistula can achieve comparable effectiveness and recurrence rate and shows benefits of shorter time to wound healing, less postoperative anal distension, less wound pain, and better anal function.…”
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“THE MIGHT-HAVE-BEENS” AS METAPLOT IN JULIAN BARNES’ STORYBOOK “THE LEMON TABLE” by Elena S. Annenkova

“…“The might-have-beens” metaplot will show the peculiarities of the heroes’ characters and their reactions to life situations, which will be the result of their individual life fears and complexes, aggravated by the limit situation of imminent death. …”
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Structural and functional insights into the pilotin-secretin complex of the type II secretion system. by Shuang Gu, Saima Rehman, Xiaohui Wang, Vladimir E Shevchik, Richard W Pickersgill

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Digital core reconstruction of tight carbonate rocks based on SliceGAN by Ying Zhou, Taiping Zhao, Wenjing Zhang, Feiqi Teng, Xin Nie

“…This study provided a new sight for reconstructing cores with complex pore structures and strong heterogeneity and innovatively supports tight carbonate reservoir characterization and evaluation.…”
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Expression of Tight Junction Protein Claudin-1 in Human Crescentic Glomerulonephritis by Ryo Koda, Atsunori Yoshino, Yuji Imanishi, Shinya Kawamoto, Yoshihiko Ueda, Eishin Yaoita, Junichiro James Kazama, Ichiei Narita, Tetsuro Takeda

“…Co-localization of claudin-1 with ZO-1 implies the formation of functional tight junction complexes in crescentic lesions to prevent the interstitial damage caused by penetration of filtered molecules from Bowman’s space.…”
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Effect Evaluation of Staged Fracturing and Productivity Prediction of Horizontal Wells in Tight Reservoirs by Yuan Zhang, Jianyang Chen, Zhongbao Wu, Yuxiang Xiao, Ziyi Xu, Hanlie Cheng, Bin Zhang

“…Due to the interference of multiple physical parameters and the complex functional relationship in the development of tight reservoir fracturing, the traditional prediction method has low accuracy and it is difficult to establish an accurate mapping relationship. …”
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How health mediation can function effectively on the fostering of healthcare utilization? : a realist qualitative study by Elodie Richard, Leila Ramiz, Mara Oltean, Vanina Troussier, Caroline Ulracher, Olivia Speed, Muriele Conort, Cécile Coutant, Fréderique Chaves Quirino, Judith Martin Fernandez, Stéphanie Vandentorren, Linda Cambon

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A refined model of claudin-15 tight junction paracellular architecture by molecular dynamics simulations. by Giulio Alberini, Fabio Benfenati, Luca Maragliano

“…The tight-junction backbone is made of strands of transmembrane proteins from the claudin family, but the molecular mechanism of its function is still not completely understood. …”
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Mechanism of intestinal tight junction transmembrane proteins interaction with egg white peptides RVPSL and QIGLF by Zhipeng Yu, Di Liu, Long Ding, Zhiyang Du, Wenzhu Zhao

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Generatively optimised compact 3-DoF spherical parallel manipulator with tightly integrated actuators by Kartikeya Walia, William Navaraj, Philip Breedon

“…The integration of actuators within a generatively optimized structure offers a compact, lightweight solution and a high-performance alternative for applications demanding singularity-free motion and reduced actuation-complexity. Future work will extend this design to higher payload systems using metal components, enhancing durability and functionality for industrial applications.…”
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Complex Medium-Chain Triglycerides Mitigate Porcine Epidemic Diarrhea Virus Infection in Piglets by Enhancing Anti-Inflammation, Antioxidation, and Intestinal Barrier Function by Tingting Hu, Yunhao Liu, Sihui Gao, Xiaonan Zhao, Huangzuo Cheng, Youjun Hu, Huaqiao Tang, Zhiwen Xu, Chunlin Fang

“…Expression of intestinal tight junction proteins claudin-1 and ZO-1 was restored. …”
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Alteration of Tight and Adherens Junctions on 50-Hz Magnetic Field Exposure in Madin Darby Canine Kidney (MDCK) Cells by Zoltán Somosy, Zsolt Forgács, Gabriella Bognár, Katalin Horváth, Gyözo Horváth

“…Adherens (AJ) and tight junctions (TJ), as integrated parts of the junctional complex, are multifunctional specialized regions of the cell membrane in epithelial cells. …”
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TIMP1 inhibits Rac1-mediated ROS production to ameliorate blood–spinal cord barrier disruption in amyotrophic lateral sclerosis by Jingshu Tang, Yuying Kang, Qiuyu Chen, Baodan Zhang, Nianying Shang, Jiaqi Lan, Lei Wu, Ying Peng

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PERHITUNGAN NUMERIK RAPAT KEADAAN GRAPHENE BILAYER DENGAN MODEL TIGHT-BINDING MENGGUNAKAN METODE RAMBATAN WAKTU TROTTER-SUZUKI by Wahyu Setiawan

“…The generation of the initial wave function  is carried out by using a random complex number as a superposition function of the base of each hexagonal structure atomic site to obtain the correlation function. …”
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Handling Multiple-Fuel Options in Economic Dispatch of Thermal Power Plants Through a Tight Model Applying Indicator Variables by Hossein Sharifzadeh

“…The inclusion of these binary variables and nonlinear cost functions results in a complex NP-hard mixed-integer nonlinear programming (MINLP). …”
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Case Report: Treatment of a complex hand disfigurement injury by fully shaped reconstruction of a severed finger combined with ectopic banking by Zhengfeng Jia, Zhengfeng Jia, Zhengfeng Jia, Longbao Shi, Weilu Gao, Weilu Gao, Weilu Gao, Han Li, Jianzheng Zhang, Weidong Shi, Jiantao Li, Jiantao Li, Jianwen Zhao

“…One of the primary challenges in hand microsurgical reconstruction lies in addressing severe hand injuries, particularly those involving multiple finger amputations, as autologous replantation might not fully restore hand functionality. In such scenarios, fully shaped reconstruction of a severed finger combined with Ectopic banking could yield superior reconstructive outcomes and enhance the amputated limb's function. …”
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A feedback circuitry involving γ-actin, β-actin and nonmuscle myosin-2 A controls tight junction and apical cortex mechanics by Marine Maupérin, Yuze Sun, Thomas Glandorf, Tabea Anne Oswald, Niklas Klatt, Burkhard Geil, Annick Mutero-Maeda, Isabelle Méan, Lionel Jond, Andreas Janshoff, Jie Yan, Sandra Citi

“…Abstract Cytoplasmic β- and γ-actin isoforms, along with non-muscle myosin 2 isoforms, are tightly regulated in epithelial cells and compose the actomyosin cytoskeleton at the apical junctional complex. …”
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Complex Loci in human and mouse genomes. by Pär G Engström, Harukazu Suzuki, Noriko Ninomiya, Altuna Akalin, Luca Sessa, Giovanni Lavorgna, Alessandro Brozzi, Lucilla Luzi, Sin Lam Tan, Liang Yang, Galih Kunarso, Edwin Lian-Chong Ng, Serge Batalov, Claes Wahlestedt, Chikatoshi Kai, Jun Kawai, Piero Carninci, Yoshihide Hayashizaki, Christine Wells, Vladimir B Bajic, Valerio Orlando, James F Reid, Boris Lenhard, Leonard Lipovich

“…To determine the incidence, functional significance, and evolutionary context of mammalian complex loci, we identified and characterized 5,248 cis-antisense pairs, 1,638 bidirectional promoters, and 1,153 chains of multiple cis-antisense and/or bidirectionally promoted pairs from 36,606 mouse transcriptional units (TUs), along with 6,141 cis-antisense pairs, 2,113 bidirectional promoters, and 1,480 chains from 42,887 human TUs. …”
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