Identification and validation of a novel autoantibody biomarker panel for differential diagnosis of pancreatic ductal adenocarcinoma by Metoboroghene O. Mowoe, Metoboroghene O. Mowoe, Hisham Allam, Joshua Nqada, Marc Bernon, Karan Gandhi, Sean Burmeister, Urda Kotze, Miriam Kahn, Christo Kloppers, Suba Dharshanan, Zafirah Azween, Pamela Maimela, Paul Townsend, Eduard Jonas, Jonathan M. Blackburn, Jonathan M. Blackburn

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Targeting hyperlipidemia: A polarity-driven ternary extraction of Apium graveolens bioactives—A coupled in-vivo, in-vitro and in-silico investigation by Nargis Sultana Chowdhury, Tasnuva Sharmin Zaman, Rifah Noor Chowdhury, Md Abdur Rahman, Sheikh Rakibul Alam, Romana Akter, Md. Nazmus Samdani, Syeda Sadia Afrin, Md. Rafat Tahsin, Fahima Aktar, Ishrat Jahan, Nasiba Binte Bahar, Salehuddin Ayubee, Umme Habiba Ria, Md Zakir Sultan, Mohammad Borhan Uddin, Jakir Ahmed Chowdhury, Md. Selim Reza, Abu Asad Chowdhury, Shaila Kabir, Md. Shah Amran

“…However, in our solvent system we enhance the polarity by adding 15 % water so more hydrophilic compounds could be present in the extract. …”
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Hemoglobin state-flux: A finite-state model representation of the hemoglobin signal for evaluation of the resting state and the influence of disease. by Randall L Barbour, Harry L Graber, San-Lian S Barbour

“…Inspection of the coefficient arrays reveals that they are governed predominantly by first-order rate processes, and that each array class exhibits preferred structure that is mainly independent of the others. …”
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Research on the charging periods of the ultra-shallow play in front of the Hashan area, northwestern margin of the Junggar Basin by WANG Qianjun, ZHOU Jian, ZHANG Faqiang, YU Hongzhou, WU Qianqian, LU Hongli, LIU Qingxin, ZHOU Yu, CHENG Ming, YAN Jianzhao, LYU Yanfang

“…Objective  The Hala’alat Mountain front-overthrust belt, renowned for its abundant hydrocarbon resources, is characterized by multi-layer oil-bearing systems and intricate source-reservoir relationships. …”
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ALMA Spectral Survey of an Eruptive Young Star, V883 Ori (ASSAY). II. Freshly Sublimated Complex Organic Molecules in the Keplerian Disk by Jae-Hong Jeong, Jeong-Eun Lee, Seonjae Lee, Giseon Baek, Ji-Hyun Kang, Seokho Lee, Chul-Hwan Kim, Hyeong-Sik Yun, Yuri Aikawa, Gregory J. Herczeg, Doug Johnstone, Lucas Cieza

“…We present an investigation of complex organic molecules (COMs) in the spatially resolved Keplerian disk around V883 Ori, an eruptive young star, based on a spectral survey carried out with the Atacama Large Millimeter/submillimeter Array in Band 6 (220.7−274.9 GHz). We identified about 3700 molecular emission lines and discovered 23 COMs in the disk. …”
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Microneedle Patch for In Situ Neutrophil Monitoring by Ziyi Lu, Ruisi Cai, Tianao Xie, Sheng Zhao, Sarun Juengpanich, Win Topatana, Shijie Li, Jiasheng Cao, Jiahao Hu, Tianen Chen, Jiachen Chen, Jicheng Yu, Tao Sheng, Wentao Zhang, Hao Wang, Jiahuan You, Yukai Shan, Yuchao Sun, Ruijing Shen, Zhengjie Zhao, Kangfan Ji, Ziqi Gao, Xinmin Yu, Xiujun Cai, Zhen Gu, Yuqi Zhang, Mingyu Chen

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Understanding Infection, Viral Exacerbation and Respiratory Symptoms at Admission-Longitudinal (UNIVERSAL) study: a prospective observational cohort study protocol by Nicola White, James D Chalmers, Salman Siddiqui, Paul H Lee, Cyrus Daneshvar, James Raftery, Charles Roberts, Philip Mitchelmore, Kerensa Thorne, Stefan J Marciniak, Tom Wilkinson, Angelica Cazaly, Gareth Griffiths, Neil J Greening, Anna Freeman, Alexander Allen, Andrew Cook, Karl J Staples, Tommaso Morelli, Jacqueline Nuttall, James Myerson, Olivia Cox, Emma Chamberlain, Tristan William Clark, Martha Purcell, Pedro Rodrigues, Matthew Pavitt, Michael G Crooks, Emma Tilt, Emma Knox, Monica Gil, Max Ellis, Ingrid Seath, Sandy Aitken, Barbara Costa, Sarah Dudley

“…Adults admitted with respiratory symptoms who test positive for RVIs via the BioFire® FilmArray® System or other validated diagnostic PCR tests will be enrolled. …”
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Identification of HMOX-1-Targeting Natural Compounds in <i>Camellia nitidissima</i> Chi for NSCLC Therapy: Integrating Bioassay and In Silico Screening Approaches by Lingqiu Zhang, Fan Zhang, Haimei Liang, Xiangling Qin, Chunmei Liang, Manlu Zhong, Yuemi Mo, Jinling Xie, Xiaotao Hou, Jiagang Deng, Erwei Hao, Zhengcai Du

“…Ferroptosis was verified via transmission electron microscopy (TEM), biochemical indicators, a PCR Array, and immunofluorescence. The bioactive compounds were identified using UPLC-Q Exactive MS, and their binding affinity to HMOX-1 was evaluated via molecular docking and dynamics simulations, followed by cellular validation. …”
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Interplay of coprecipitation and adsorption processes: deciphering amorphous mineral–organic associations under both forest and cropland conditions by F. Jamoteau, F. Jamoteau, F. Jamoteau, F. Jamoteau, E. Doelsch, E. Doelsch, N. Cam, C. Levard, T. Woignier, T. Woignier, A. Boulineau, F. Saint-Antonin, S. Swaraj, G. Gassier, A. Duvivier, D. Borschneck, M.-L. Pons, P. Chaurand, V. Vidal, N. Brouilly, I. Basile-Doelsch

“…However, conversion from forest to agricultural systems disrupts these associations, leading to carbon loss and reduced soil fertility in croplands. …”
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What do arc magmatism trace-element patterns and Sr–Nd–Pb isotopic data reflect? Insights from the Urumieh–Dokhtar magmatic arc of Iran by M. R. Ghorbani, M. Akbari, M. Akbari, I. T. Graham, M. Benoit, F. Sepidbar

“…The mafic volcanic rocks, which extend from the mantle array (i.e., the NHRL; Northern Hemisphere reference line) toward an enriched mantle, on the Pb–Pb isotopic plots, further support this finding. …”
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Predicting Insemination Outcome in Holstein Dairy Cattle using Deep Learning by Mohammad Alishahi, Mahdi Ravakhah

“…The integration of predicting models in the existing systems in animal husbandry increases its practical application as a decision support tool for animal farmers. …”
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Embedding a Choice Experiment in an Online Decision Aid or Tool: Scoping Review by Nyantara Wickramasekera, Phil Shackley, Donna Rowen

“…MethodsThis scoping review followed the PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses extension for Scoping Reviews) guidelines. …”
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All‐in‐one perovskite memristor with tunable photoresponsivity by Guan‐Hua Dun, Yuan‐Yuan Li, Hai‐Nan Zhang, Fan Wu, Xi‐Chao Tan, Ken Qin, Yi‐Chu He, Ze‐Shu Wang, Yu‐Hao Wang, Tian Lu, Shi‐Wei Tian, Dan Xie, Jia‐Li Peng, Xiang‐Shun Geng, Xiao‐Tong Zhao, Jia‐He Zhang, Yu‐Han Zhao, Xiaoyu Wu, Ning‐Qin Deng, Zheng‐Qiang Zhu, Yan Li, Xian‐Zhu Liu, Xing Wu, Weida Hu, Peng Zhou, Yang Chai, Mario Lanza, He Tian, Yi Yang, Tian‐Ling Ren

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PSZ2 G181.06+48.47. II. Radio Analysis of a Low-mass Cluster with Exceptionally Distant Radio Relics by Kamlesh Rajpurohit, Andra Stroe, Ewan O’Sullivan, Eunmo Ahn, Wonki Lee, Hyejeon Cho, M. James Jee, Reinout van Weeren, Lorenzo Lovisari, Kyle Finner, Aurora Simionescu, William Forman, Timothy Shimwell, Christine Jones, Zhenlin Zhu, Scott Randall

“…We report upgraded Giant Metrewave Radio Telescope and Karl J. Jansky Very Large Array radio observations of a low-mass merging galaxy cluster PSZ2 G181.06+48.47. …”
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The Gaseous Blowout of the 30 Doradus Starburst Region in the LMC by Suraj Poudel, April Horton, Jo Vazquez, Kathleen A. Barger, Frances H. Cashman, Andrew J. Fox, Nicolas Lehner, Scott Lucchini, Dhanesh Krishnarao, N. M. McClure-Griffiths, Elena D’Onghia, Jason Tumlinson, Ananya Goon Tuli, Lauren Sdun, Stone Gebhart, Katherine Anthony, Bryce Cole, Jacco Th. van Loon, Julia Roman-Duval, Yik Ki Ma, Callum Lynn, Min-Young Lee, Denis Leahy

“…Finally, our hydrodynamical simulations of the Magellanic Clouds and MW system suggest that the Magellanic Corona can protect the LMC winds from the ram pressure forces exerted by the MW’s halo.…”
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IL-19 as a promising theranostic target to reprogram the glioblastoma immunosuppressive microenvironment by Gilbert Aaron Lee, Justin Bo-Kai Hsu, Yu-Wei Chang, Li-Chun Hsieh, Yi-Tien Li, Ying Chieh Wu, Cheng-Ying Chu, Yung-Hsiao Chiang, Wan-Yuo Guo, Chih-Chun Wu, Liang-Wei Chen, Hung-Wen Kao, Wan-Li Lin, Li‑Wen Tseng, Ting-Wei Weng, Duen-Pang Kuo, Sho-Jen Cheng, Yung-Chieh Chen, Shiu-Wen Huang, Hsing-Jien Kung, Cheng-Yu Chen

“…Prussian blue staining further confirmed the localization of these nanoparticles in tumor tissues, verifying their potential as a diagnostic tool for detecting IL-19 expression in glioblastoma. This system offers a theranostic approach, integrating diagnostic imaging and targeted therapy for IL-19-expressing GBM. …”
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Basic Cells Special Features and Their Influence on Global Transport Properties of Long Periodic Structures by Luna R. N. Oliveira, Marcos G. E. da Luz

“…In this contribution, we address quantum transport in long periodic arrays whose basic cells, localized potentials <inline-formula><math xmlns="http://www.w3.org/1998/Math/MathML" display="inline"><semantics><mrow><mi>U</mi><mo>(</mo><mi>x</mi><mo>)</mo></mrow></semantics></math></inline-formula>, display certain particular features. …”
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Health position paper and redox perspectives – Bench to bedside transition for pharmacological regulation of NRF2 in noncommunicable diseases by Antonio Cuadrado, Eduardo Cazalla, Anders Bach, Boushra Bathish, Sharadha Dayalan Naidu, Gina M. DeNicola, Albena T. Dinkova-Kostova, Raquel Fernández-Ginés, Anna Grochot-Przeczek, John D. Hayes, Thomas W. Kensler, Rafael León, Karen T. Liby, Manuela G. López, Gina Manda, Akshatha Kalavathi Shivakumar, Henriikka Hakomäki, Jessica A. Moerland, Hozumi Motohashi, Ana I. Rojo, Gerasimos P. Sykiotis, Keiko Taguchi, Ángela M. Valverde, Masayuki Yamamoto, Anna-Liisa Levonen

“…Its dysregulation is implicated in the progression of a wide array of human diseases, making NRF2 a compelling target for therapeutic interventions. …”
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The changing face of the Arctic: four decades of greening and implications for tundra ecosystems by Gerald V. Frost, Uma S. Bhatt, Matthew J. Macander, Logan T. Berner, Donald A. Walker, Martha K. Raynolds, Rúna Í. Magnússon, Annett Bartsch, Jarle W. Bjerke, Jarle W. Bjerke, Howard E. Epstein, Bruce C. Forbes, Scott J. Goetz, Elizabeth E. Hoy, Elizabeth E. Hoy, Stein R. Karlsen, Timo Kumpula, Trevor C. Lantz, Mark J. Lara, Efrén López-Blanco, Paul M. Montesano, Paul M. Montesano, Christopher S. R. Neigh, Ingmar Nitze, Kathleen M. Orndahl, Taejin Park, Taejin Park, Gareth K. Phoenix, Adrian V. Rocha, Brendan M. Rogers, Gabriela Schaepman-Strub, Hans Tømmervik, Mariana Verdonen, Mariana Verdonen, Alexandra Veremeeva, Anna-Maria Virkkala, Christine F. Waigl

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The ALMA Survey of Gas Evolution of PROtoplanetary Disks (AGE-PRO). I. Program Overview and Summary of First Results by Ke Zhang, Laura M. Pérez, Ilaria Pascucci, Paola Pinilla, Lucas A. Cieza, John Carpenter, Leon Trapman, Dingshan Deng, Carolina Agurto-Gangas, Anibal Sierra, Nicolás T. Kurtovic, Dary A. Ruiz-Rodriguez, Miguel Vioque, James Miley, Benoît Tabone, Camilo González-Ruilova, Rossella Anania, Giovanni P. Rosotti, Estephani TorresVillanueva, Michiel R. Hogerheijde, Kamber Schwarz, Aleksandra Kuznetsova

“…We present the Atacama Large Millimeter/submillimeter Array Survey of Gas Evolution of PROtoplanetary Disks (AGE-PRO), a large program of the ALMA. …”
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