Discovery of a novel highly specific, fully human PSCA antibody and its application as an antibody-drug conjugate in prostate cancer by Xiaojie Chu, Seungmin Shin, Du-San Baek, Liyong Zhang, Alex Conard, Megan Shi, Ye-Jin Kim, Cynthia Adams, Maggie Hines, Xianglei Liu, Chuan Chen, Zehua Sun, Dontcho V. Jelev, John W. Mellors, Dimiter S. Dimitrov, Wei Li

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Aging-dependent change in Th17 and cytokine response in multiple sclerosis by Wen Zhu, Shankar Revu, Chenyi Chen, Megan Dahl, Archana Ramkumar, Conor Kelly, Mandy J. McGeachy, Zongqi Xia

“…Abstract Background Multiple sclerosis (MS) is a chronic autoimmune disease damaging the central nervous system. Diminished inflammatory disease activity (DA) as people with MS (pwMS) age motivated randomized clinical trials assessing disease-modifying therapy (DMT) discontinuation in older pwMS given the concern for risks outweighing benefits. …”
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Design, Synthesis, and Antiproliferative Activity of Novel Indole/1,2,4-Triazole Hybrids as Tubulin Polymerization Inhibitors by Esraa Mahmoud, Dalia Abdelhamid, Anber F. Mohammed, Zainab M. Almarhoon, Stefan Bräse, Bahaa G. M. Youssif, Alaa M. Hayallah, Mohamad Abdel-Aziz

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Comparison of chip size effects of thin film GaN-based μLEDs fabricated by plasma etching and ion implantation processing by Tsung-Chih Wan, Ping-Hsun Tsai, Hao-Wu Lin, Chien-Chung Lin, Dong-Sing Wuu, Hiroshi Amano, Tae-Yeon Seong, Ray-Hua Horng

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Research Trends in the Field of Participatory Governance: Drawing a Map of Co-occurrence and Co-word Analysis by Seyed Mohsen Mirbagheri, Seyed Mostafa Jalili

“…Experts in participatory governance face the daunting task of navigating through an extensive array of research documents to analyze the field's various strengths and weaknesses. …”
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Advancing cancer therapy with custom-built alternating electric field devices by Isobel Jobson, Nguyen T. N. Vo, Edward Kujawinski, Chris Denning, Snow Stolnik, Veeren M. Chauhan, Frankie Rawson

“…However, there is a space to design alternative systems that will be amenable for wider use in current research. …”
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Changes of cytokine profile measures during the treatment of rheumatoid arthritis with rituximab biosimilar (Acellbia, BIOCAD) and the original drug (MabThera, F. Hoffmann-La Roche... by A. S. Avdeeva, A. S. Artyukhov, E. B. Dashinimaeva, M. V. Cherkasova, E. L. Nasonov

“…The concentration of 27 cytokines in blood serum was determined by multiplex xMAP technology on the analyzer Bio-Plex Array System (BIO-RAD, USA). Results and discussion. …”
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Disaster Medicine Core Competencies: Comparative Analysis of Emergency Medicine Residency Training in Taiwan and the United States by Joyce Tay, Wei-Kuo Chou, Ming-Tai Cheng, Chih-Wei Yang, Shuo-Kuen Huang, Chien-Hao Lin

“…Background: Situated in the western Pacific Ocean, Taiwan has faced a diverse array of natural and man-made disasters. Since 2000, disaster medicine education has been progressively integrated into various medical professions, with a focus on training disaster medical assistance teams, managing chemical and radiological emergencies, and enhancing prehospital and hospital emergency management capabilities. …”
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Harnessing plant growth-promoting bacteria to combat watermelon mosaic virus in squash by Shymaa R. Bashandy, Omima Abdelsater Mohamed, Osama A. Abdalla, A. Elfarash, Mohamed Hemida Abd-Alla

“…GC–MS analysis of the six bacterial strains revealed a diverse array of 73 chemical metabolites, including common compounds such as 9-Octadecenoic acid (Z), benzene derivatives, and cyclopentanones. …”
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Salt Stress Leads to Morphological and Transcriptional Changes in Roots of Pumpkins (<i>Cucurbita</i> spp.) by Hongjiu Liu, Ding Ding, Yeshuo Sun, Ruiping Ma, Xiaoqing Yang, Jie Liu, Guoxin Zhang

“…To deal with salt stress, plants exhibit an array of responses such as changes in their root system architecture. …”
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Probing Equatorial Ionospheric TEC at Sub-GHz Frequencies with Wide-Band (B4) uGMRT Interferometric Data by Dipanjan Banerjee, Abhik Ghosh, Sushanta K. Mondal, Parimal Ghosh

“…Radio interferometers such as the giant metrewave radio telescope (GMRT) are capable of detecting changes in the ionosphere’s total electron content (TEC) over larger spatial scales and with greater sensitivity compared to conventional tools like the global navigation satellite system (GNSS). Thanks to its unique design, featuring both a dense central array and long outer arms, and its strategic location, the GMRT is particularly well-suited for studying the sensitive ionospheric region located between the northern peak of the equatorial ionization anomaly (EIA) and the magnetic equator. …”
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Hemotropic pathogens in aborted fetuses of domestic ruminants: transplacental transmission and implications for reproductive loss by Daria Jurković Žilić, Šimun Naletilić, Željko Mihaljević, Ema Gagović, Silvio Špičić, Irena Reil, Sanja Duvnjak, Maja Zdelar Tuk, Adnan Hodžić, Relja Beck

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Topical administration of GLP-1 eyedrops improves retinal ganglion cell function by facilitating presynaptic GABA release in early experimental diabetes by Yu-Qi Shao, Yong-Chen Wang, Lu Wang, Hang-Ze Ruan, Yun-Feng Liu, Ti-Hui Zhang, Shi-Jun Weng, Xiong-Li Yang, Yong-Mei Zhong

“…Moreover, multielectrode array recordings revealed that glucagon-like peptide-1 functionally augmented the photoresponses of ON-type retinal ganglion cells. …”
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<i>C11orf58</i> (Hero20) Gene Polymorphism: Contribution to Ischemic Stroke Risk and Interactions with Other Heat-Resistant Obscure Chaperones by Irina Shilenok, Ksenia Kobzeva, Vladislav Soldatov, Alexey Deykin, Olga Bushueva

“…<b>Methods</b>: 2204 Russian subjects (917 IS patients and 1287 controls) were genotyped for fifteen common SNPs in Hero20 gene <i>C11orf58</i> using probe-based PCR and the MassArray-4 system. <b>Results</b>: Six <i>C11orf58</i> SNPs were significantly associated with an increased risk of IS in the overall group (OG) and significantly modified by smoking (SMK) and low fruit/vegetable intake (LFVI): rs10766342 (effect allele (EA) A; P(_OG = 0.02; _SMK = 0.009; _LFVI = 0.04)), rs11024032 (EA T; P(_OG = 0.01; _SMK = 0.01; _LFVI = 0.036)), rs11826990 (EA G; P(_OG = 0.007; _SMK = 0.004; _LFVI = 0.03)), rs3203295 (EA C; P(_OG = 0.016; _SMK = 0.01; _LFVI = 0.04)), rs10832676 (EA G; P(_OG = 0.006; _SMK = 0.002; _LFVI = 0.01)), rs4757429 (EA T; P(_OG = 0.02; _SMK = 0.04; _LFVI = 0.04)). …”
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A SORT1/EGFR molecular interplay as a prognostic biomarker in glioblastoma vasculogenic mimicry: implications in the transcriptional regulation of cancer stemness and drug resistan... by Marie-Eve Roy, Alain Zgheib, Nicoletta Eliopoulos, Borhane Annabi

“…This was consistent with cDNA array analyses from clinically annotated GBM demonstrating higher SORT1 levels in stage III-IV compared to stage I-II tumors. …”
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Yiqi Huayu Jiedu Decoction reduces colorectal cancer liver metastasis by promoting N1 neutrophil chemotaxis by Hua-Jian Zhou, Bai-Xiang Mu, Meng-Chao Wen, Qi Zhao, Yuanxiang Li, Wen-Xuan Zhao, Hong-Ye Yin, Shuai Ren, Jin-Yong Zhou, Jin-Yong Zhou, Min Chen

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Methylation-based biological age and cardiotoxicity risk in breast cancer patients treated with trastuzumab by Jamila Mammadova, Alicia Richards, Adriana Gonzalez-Torriente, Evan R. Adler, Rachel J. Cruz, Stefanie Palfi, Dae Hyun Lee, Christine Sam, Mohammed Al-Jumayli, Anders Berglund, Jong Y Park, Mohammed Alomar, Jacob K. Kresovich

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Influence of Different Nicotine Sources on Exercise-Driven Immune Responses of Peripheral Blood Monocytes by Paul N. Axt, Theresa Mohr, Armin Steffen, Kirstin Plötze-Martin, Nele Jagodzinski, Sabine Bohnet, Daniel Drömann, Karl-Ludwig Bruchhage, Klaas F. Franzen, Ralph Pries

“…Plasma cytokines were evaluated using membrane-based cytokine arrays and enzyme-linked immunosorbent assays (ELISA). …”
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Lack of HLH in FMF by Ozge Basaran, Erdal Sag, Elif Arslanoglu Aydın, Busra Aydın, Nur Kübra Tasdemir, Elif Celikel, Yagmur Bayındır, Semanur Özdel, Yelda Bilginer, Alexei A Grom, Seza Ozen

“…Abstract Background Macrophage activation syndrome (MAS) is a severe complication of systemic juvenile idiopathic arthritis (sJIA), driven by excessive activation of T cells and macrophages, resulting in a cytokine storm. …”
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The ArtemIS project: Assessment for medium-depth geothermal energy utilization in Germany by L. M. Weydt, T. Agemar, M. Erb, N. Mantei, N. Dobrzinski, J. Weber, S. Sperlich, J. van der Vaart, K. Bär, I. Moeck, I. Moeck, I. Sass, I. Sass

“…<p>To date, most geothermal projects in Germany have focused on deep geothermal systems, while resources at intermediate depths have only been explored to a small extend. …”
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