Comparative risk of QTc prolongation induced by second-generation antipsychotics in the real world: retrospective cohort study based on a hospital information system by Luyao He, Wenjuan Yu, Huiqing Song, Lujin Li, Yifeng Shen, Lei Zhang, Huafang Li

“…A marginal structural Cox model was used to compare the hazard ratios for QTc prolongation associated with various SGAs. …”
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Hmgb2 improves astrocyte to neuron conversion by increasing the chromatin accessibility of genes associated with neuronal maturation in a proneuronal factor-dependent manner by Priya Maddhesiya, Tjasa Lepko, Andrea Steiner-Mezzardi, Julia Schneider, Veronika Schwarz, Juliane Merl-Pham, Finja Berger, Stefanie M. Hauck, Lorenza Ronfani, Marco Bianchi, Tatiana Simon, Anthodesmi Krontira, Giacomo Masserdotti, Magdalena Götz, Jovica Ninkovic

“…Using this culture system, we show that chromatin structural protein high mobility group box 2 (HMGB2) regulates the direct conversion rate downstream of the growth factor combination. …”
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The Primary Care Spend Model: a systems approach to measuring investment in primary care by Robert Phillips, Michael Kidd, Viviana Martinez-Bianchi, Martin Roland, Jennifer DeVoe, Hong Wang, Robert Baillieu, Michael Mueller, David Morgan, Bruce Landon, Rebecca Etz, Chris Koller, Neha Sachdev, Hannah Jackson, Yalda Jabbarpour, Andrew Bazemore

“…The model articulates varied definitions of primary care through a tiered structure which includes overall spending on primary care services, spending on services delivered by primary care professionals and spending delivered by providers that can be characterised by the ‘4Cs’ (first contact, continuous, comprehensive and coordinated care). …”
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Effects of Solidification Thermal Variables on the Microstructure and Hardness of the Silicon Aluminum Bronze Alloy CuAl₆Si₂ by Paulo Henrique Tedardi do Nascimento, Vinicius Torres dos Santos, Ricardo de Luca, Marcio Rodrigues da Silva, Flavia Goncalves Lobo, Rogerio Teram, Mauricio Silva Nascimento, Ronaldo Camara Cozza, Antonio Augusto Couto, Givanildo Alves dos Santos, Anibal de Andrade Mendes Filho

“…An optical microscope, scanning electron microscope (SEM), and X-ray diffraction (XRD) were used to verify the fusion structure and determine the volumetric fraction of the formed phases. …”
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‘When I tried to explain, they shouted back at me!’: exploring how community pharmacists navigate tensions implementing antimicrobial stewardship in Vietnam by Duy Trinh Hoang, Shannon McKinn, Dorothy Drabarek, Thao Thu Trieu, Van Thuy Pham, Yen Ngoc Pham, Thai Hung Cao, Hung Mai Tran, Greg J. Fox, Thu-Anh Nguyen, Sarah Bernays

“…This qualitative analysis draws on data from 24 in-depth interviews with licensed community pharmacists in Vietnam. …”
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The Impact of Nitrogen Addition on Soil Carbon Components and Understory Vegetation in Moso Bamboo Forests by Zhoubin Huang, Xiaotong Liu, Haoyu Chu, Hao Jia, Xianxian He, Canying Wang, Bing Zhang, Chuanxia Pan, Sufan Liu, Shaohui Fan, Wenhui Su

“…Nitrogen reshaped the community structure, notably affecting dominant species such as <i>Viola davidii</i> and <i>Rubus buergeri.…”
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Comparative Immunogenicity in Rabbits of the Polypeptides Encoded by the 5′ Terminus of Hepatitis C Virus RNA by Irina Sominskaya, Juris Jansons, Anastasija Dovbenko, Natalia Petrakova, Ilva Lieknina, Marija Mihailova, Oleg Latyshev, Olesja Eliseeva, Irina Stahovska, Inara Akopjana, Ivars Petrovskis, Maria Isaguliants

“…Recent studies on the primate protection from HCV infection stressed the importance of immune response against structural viral proteins. Strong immune response against nucleocapsid (core) protein was difficult to achieve, requesting further experimentation in large animals. …”
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Heterojunction Derived Efficient Charge Separation for High Sensitivity Self‐Powered Flexible Photodetectors toward Real‐Time Heart Rate Monitoring by Nan Ding, Ge Zhu, Xiaotao Zhang, Wen Xu, Hailong Liu, Yanan Ji, Yuanzheng Chen, Bin Dong

“…Meanwhile, the high hole mobility and suitable energy band structure of p‐type SnS QDs are doped into spiro‐OMeTAD HTL, which can improve the hole extraction, and balance electron and hole mobilities. …”
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Diversified Cropping Modulates Microbial Communities and Greenhouse Gas Emissions by Enhancing Soil Nutrients by Zhongyan Wang, Huaqiang Xuan, Bei Liu, Hongfeng Zhang, Tongyan Zheng, Yunxia Liu, Luping Dai, Yi Xie, Xianchao Shang, Li Zhang, Long Yang, Sitakanta Pattanaik, Ling Yuan, Xin Hou

“…Therefore, we conducted a quantitative bibliometric analysis of observed data between 2014 and 2024 to identify current research hotspots and future research trends in intercropping and crop rotation. …”
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Incorporating the voice of young people in mental health research: reflections from three lived experience advisory panels in Latin America by Liliana Hidalgo-Padilla, Daniela Ramirez-Meneses, Karen Ariza-Salazar, Santiago Cesar Lucchetti, Natividad Olivar, Diliniya Stanislaus Sureshkumar, Catherine Fung, Luis Ignacio Brusco, Carlos Gómez-Restrepo, José Miguel Uribe-Restrepo, Stefan Priebe, Francisco Diez-Canseco

“…Future efforts should focus on overcoming structural limitations and fostering equitable collaboration, emphasising the need for youth perspectives in mental health research, particularly in low- and middle-income countries.…”
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Genome-Wide Analysis of GRETCHEN HAGEN3 Genes and Characterization of IAA-Amido Synthetase Gene <i>CsGH3.1</i> in Rhizome Proliferation in <i>Cymbidium sinense</i> ‘Qijianbaimo’... by Sisi Jia, Cuiling Liu, Chushu Liao, Ruizhen Zeng, Li Xie, Qian Wei, Zhisheng Zhang

“…Gene structure analysis showed that <i>CsGH3s</i> contain one to four exons, and their promoter regions feature auxin and jasmonic acid response elements. …”
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Impacts of habitat modification on the dynamics of waterbird diversity in Guangzhou Haizhu National Wetland Park by Zhouhan Chen, Xiaoshan Fang, Shangjiangfeng Lin, Xuefei Zhang, Dongmei Yu, Yuanzhihong Liu, Xiqing Liu, Huijian Hu

“…By 2022, significant changes in habitat structure had occurred, making it an important site for waterbird aggregation. …”
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Impact of Early-Life Brain Injury on Gut Microbiota Composition in Rodents: Systematic Review with Implications for Neurodevelopment by Vanessa da Silva Souza, Raul Manhães-de-Castro, Sabrina da Conceição Pereira, Beatriz Souza de Silveira, Caio Matheus Santos da Silva Calado, Henrique José Cavalcanti Bezerra Gouveia, Jacques-Olivier Coq, Ana Elisa Toscano

“…Eligible studies focused on evaluating the microbiota alterations and related gut–brain axis markers at the neonatal or post-weaning stages. The data extraction and synthesis followed PRISMA guidelines. …”
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Short- and long-term outcomes of Impella-protected, high-risk, elective PCI in patients with multivessel coronary disease and low ejection fraction — Polish Impella Registry by Wojciech J. Skorupski, Arkadiusz Pietrasik, Aleksandra Gąsecka, Jerzy Sacha, Tomasz Pawłowski, Gabriel Bielawski, Wojciech Balak, Adam Sukiennik, Paulina Burzyńska, Adam Witkowski, Mateusz Warniełło, Łukasz Rzeszutko, Stanisław Bartuś, Artur Pawlik, Mateusz Kaczyński, Robert Gil, Wiktor Kuliczkowski, Krzysztof Reczuch, Marcin Protasiewicz, Jacek Legutko, Paweł Kleczyński, Piotr Wańczura, Sebastian Gurba, Anna Kochanowska, Michał Łomiak, Maciej Krajsman, Włodzimierz Skorupski, Maciej Zarębiński, Piotr Pawluczuk, Szymon Włodarczak, Adrian Włodarczak, Krzysztof Ściborski, Artur Telichowski, Mieszko Pluciński, Jarosław Hiczkiewicz, Karolina Konsek, Michał Hawranek, Mariusz Gąsior, Jan Peruga, Marcin Fiutowski, Robert Romanek, Piotr Kasprzyk, Dariusz Ciećwierz, Andrzej Ochała, Wojciech Wojakowski, Janusz Kochman, Maciej Lesiak, Marek Grygier

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Predicting present and future habitats using LiDAR to integrate research and monitoring with landscape analyses by David A. MacLean, Thomas Baglole, Maurane Bourgouin, Billie Chiasson, Jiban C. Deb, Maitane Erdozain, Remus J. James, Lauren Negrazis, Louka Tousignant, Phil Wiebe, Greg Adams, Joseph R. Bennett, Erik J.S. Emilson, Nicole J. Fenton, Graham J. Forbes, Michelle A. Gray, Karen A. Kidd, Andrew McCartney, Gaetan Moreau, Kevin B. Porter, Osvaldo Valeria, Lisa A. Venier

“…LiDAR-based enhanced forest inventory provided forest structure variables that improved bird habitat models and spatial predictions of bird habitat, metrics explaining bryophyte composition and richness, and variability in beetle abundance and richness. …”
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Climate Change Risk, Performance, and Value Added in Agricultural Sector by Ramin Amani, Zanko Ghorbani, Zana Mozaffari

“…The study period spans from 2010 to 2020, and the quantile regression method is employed on panel data to conduct the analysis. Methodology The general definition of quantile regression states that if the linear regression model is assumed as the following equation, we have: yi=ˊxiβτ+uτi.  0<τ<1                                                                                 (1) Quantτ(yi|xi)=xiβτ                                                                                  (2) Equation (2) shows the τth conditional quantile function of the y distribution under the condition of random variables x in which the following condition holds: Quantτ(uτi|xi)=0                                                                                              (3) In the quantile regression structure, the effect of observable features on the conditional distribution is estimated through the process of minimizing the absolute value of the error element. …”
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Comprehensive analysis of the electronic, thermodynamic, and spectroscopic properties of a Cu(II)-based complex with 1,10-phenanthroline and L-glutamine by Marinaldo V. Souza Junior, João G. Oliveira Neto, Walajhone O. Pereira, Jéssica A.O. Rodrigues, Jailton R. Viana, Aramys S. Reis, Mateus R. Lage, Guilherme G.C. Carvalho, Cláudia O. Pessoa, Adenilson O. dos Santos, Francisco F. de Sousa

“…A computational analysis of the intermolecular interactions using Hirshfeld surfaces was also performed, which demonstrated that the H⋯O/O⋯H and H⋯H interactions are mainly responsible for the structural and thermal stability of the complex. The calculated intramolecular vibration bands showed a good correlation with the experimental Raman and infrared (IR) data, although solvation effects caused some wavenumber shifts. …”
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63Fe–63Mn: A Possible Strong Urca Pair and Its Potential Astrophysical Impact by Hao Huang, Kuoang Li, Zhong Liu, Xiaodong Tang, Peng Shuai, Zach Meisel

“…To investigate the cooling effect of this Urca pair on the thermal evolution of neutron star crusts, we performed simulations on neutron star structure and evolution under various spin-parity assignment scenarios. …”
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Analysis of physiological and biochemical changes and metabolic shifts during 21-Day fasting hypometabolism by Zhongquan Dai, Hongyu Zhang, Xiukun Sui, Feng Wu, Cheng Zhang, Zhiqi Fan, Hailong Wang, Yaxiu Guo, Chao Yang, Siyu Jiang, Linjie Wang, Bingmu Xin, Yinghui Li

“…Heart function showed functional adaptive changes without structural damage. Prolonged fasting can reduce the body’s resting energy expenditure and adapt to body weight loss through physiological regulatory mechanisms without adverse effects on basic physiological functions or the structure of important organs. …”
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Deep-learning based multi-modal models for brain age, cognition and amyloid pathology prediction by Chenxi Wang, Weiwei Zhang, Ming Ni, Qiong Wang, Chang Liu, Linbin Dai, Mengguo Zhang, Yong Shen, Feng Gao

“…Abstract Background Magnetic resonance imaging (MRI), combined with artificial intelligence techniques, has improved our understanding of brain structural change and enabled the estimation of brain age. …”
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