Design, Synthesis, and Evaluation of Nitroxide Radical Derivatives Based on Rhein as Potential Anti-Aging Agents Targeting the Keap1-Nrf2 Pathway by Wang J, Peng X, Zhang X, Lin J, Zhang Q, Li J, Cui L, Zhao L

“…It significantly improved the survival rate of L02 hepatocytes under oxidative stress, maintaining 95.42% viability (p < 0.01). In the C. elegans model, 4b extended the average lifespan and enhanced stress resistance, increasing GSH activity, reducing MDA content, and decreasing ROS accumulation. …”
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Association between outdoor light at night exposure and preterm birth and effect modification by pre-pregnancy stress: A national population-based retrospective cohort study by Manman Chen, Qiongjie Zhou, Yuanyuan Li, Qu Lu, Anying Bai, Fangyi Ruan, Yandan Liu, Yu Jiang, Xiaotian Li

“…ALAN exposure was quantified using satellite data, and pre-pregnancy stress was assessed via a structured questionnaire focusing on life, friend, economic, and total stress. …”
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International mobility experiences among Italian students: a cross-sectional survey comparing motivations towards high- versus low-income countries by Giovanni Putoto, Pietro Invernizzi, Maria Grazia Strepparava, Marco Bani, Selena Russo, Federico Zorzi, Alexia Del Greco, Stefano Ardenghi, Giulia Rampoldi

“…Additionally, high school students reported greater overall interest in IMEs than undergraduates (4.03±1.04 vs 3.42±1.25; Z=−4.895, p<0.001). Structural equation modelling with bootstrapping confirmed these patterns (all path p<0.001), with 95% CIs indicating robust associations.Conclusions The findings suggest that tailored educational interventions integrating global health principles may enhance the motivation for IMEs, with distinct motivational drivers for high- versus low-income country destinations. …”
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Orientações para filhos de pai/mãe cardiopatas: possibilidades e abordagens [Guidance for children of fathers/mothers with heart disease: possibilities and approaches] [Orientacion... by Cláudia Zamberlan, Saul Ferraz de Paula, Hedi Crecencia Heckler de Siqueira, Dirce Stein Backes, Jeferson Ventura

“…Method: Grounded Theory provided the methodological frame of reference for data collection by semi-structured interview and observation of 11 children of mothers/fathers with heart disease, and as a technique of data analysis at theoretical saturation. …”
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Intención de volver a participar en un evento deportivo en el medio natural: prácticas verdes y cali-dad de resultado como antecedentes (Intention to re-participate in a natural en... by Karla Chaves-Castro, Guillermo Morán-Gámez, Román Nuviala, Antonio Fernández-Martínez

“…Descriptive statistics, Cronbach's alpha, AVE, FC, and structural model analysis were calculated for data analysis. …”
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How do children understand and respond to the EQ-5D-Y-3L? A mixed methods study in a community-based sample of 6–12-year-olds by Diana Khanna, Kiri Lay, Jyoti Khadka, Christine Mpundu-Kaambwa, Julie Ratcliffe, in collaboration with the Quality of Life in Kids: Key evidence to strengthen decisions in Australia (QUOKKA) project team

“…Methods A mixed methods study was conducted in a community-based sample of 39 children aged 6–12 years. In a semi-structured interview, children self-completed the EQ-5D-Y-3L and then engaged in retrospective think-aloud. …”
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Factors Influencing the Response of Patients with Infantile Epileptic Spasms Syndrome to ACTH as Repeated First-Line Therapy by Wenrong Ge, Ping Pang, Ziyan Zhang, Lin Wan, Guang Yang

“…Conversely, an older age at the time of the initial first-line treatment, an older age at the onset of epileptic spasms, and patients with congenital structural abnormalities without genetic abnormalities were less likely to achieve an initial response in subsequent ACTH treatment (OR 0.85, 95% CI 0.78, 0.92, p < 0.001; OR 0.43, 95% CI 0.16, 0.82, p = 0.032; and OR 0.18, 95% CI 0.04, 0.69, p = 0.016, respectively).. …”
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Defining Health Movements and Health Needs Across the Life Course: A Qualitative Study by Alyssa Yenyi Chan, Felicia Jia Hui Chan, Lucas Jia Rong Puah, Muhammad Bin Aman Azamuddin, Priyanka Rajendram, Weng Mooi Tan, Yoek Ling Yong, Zoe Jane‐Lara Hildon

“…Focus group discussions (FGDs, n = 12) and one semi‐structured interview (altogether involving n = 52 individuals) were carried out with government and community implementation stakeholders, alongside go‐along interviews (n = 24, involving 11 volunteers, 13 programme participants) and e‐diaries (n = 37, with 22 programme participants and 15 volunteers). …”
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Continuity of care in lumbar disc herniation: a systematic review and meta-analysis providing a deeper look into postoperative efficacy by Ying Lin, Ying Lin, Qiaoling Chen, Qiaoling Chen, RouMei Wang, Bing Zhang, Bing Zhang, Rui Huang, Yiguang Bai, Yiguang Bai

“…A meta-analysis was performed using both fixed-effects and random-effects models based on heterogeneity assessment. We analyzed the data using R software version 4.2.2 and Stata software version 15.1. …”
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Challenges of integrating HIV prevention and treatment in China's border mountain regions: a grounded theory study by Sixian Du, Haoran Niu, Feng Jiang, Liwen Gong, Shan Zheng, Qi Cui, Xu Yang, Jiayan He, Rongcai Dai, Qilian Luo, Yiqing Yang

“…To capture multi-level insights, semi-structured interviews were conducted between August and December 2024 with 23 purposively selected participants, including individuals living with HIV, village doctors, healthcare providers, and local policymakers. …”
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La evaluación en educación física: representaciones sociales de profesores de establecimientos educacionales de Viña del Mar, Chile (Evaluation in physical education: social repres... by Macarena Hurtado-Guerrero, Juan Pablo Zavala-Crichton, Pablo del Val Martín, Eduardo Báez-San Martín, Rodrigo Yáñez-Sepúlveda, Claudio Hinojosa-Torres

“…The sample consisted of ten teachers working as physical education instructors in schools in Viña del Mar, Chile. Two semi-structured interviews based on the SR model were implemented to reveal the central and peripheral concepts associated with evaluation. …”
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Learning strategies in nursing sciences: Analysis of gender disparities in a Moroccan educational context by K. Ait Moussa, S. Selmaoui, N. Ouzennou

“…Results: The findings indicate an overall homogeneity between genders in the use of cognitive, metacognitive, and affective tools, with a statistically significant but weak difference in the “Structuring-Reorganization” dimension (p = 0.044, small effect size). …”
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Bacterial profile and antimicrobial susceptibility pattern of urinary tract infection among diabetic patients at Bule Hora University Teaching Hospital, Southern Ethiopia by Mohamed Esmael Gena, Getachew Bitew, Elias Chane, Negesse Cherie, Dereje Mengesha Berta, Lidetu Demoze, Muluken Walle, Kalicha Boru, Dagnamyelew Tilahun, Bisrat Birke Teketelew, Abiy Ayele Angelo

“…Sociodemographic and clinical data were gathered using a pretested structured questionnaire. Midstream urine samples were collected for bacterial culture and identification following standard microbiological procedures, with antimicrobial susceptibility testing performed using the Kirby-Bauer disk diffusion method on Mueller–Hinton agar. …”
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Evaluation of immediate and sustained effects of transitioning quality long-acting reversible contraceptives (LARCs) services to public sector health facilities in Ghana: a pre-pos... by Yuen Wai Hung, Sara Riese, Kofi Issah, Claudette A. Diogo, Nirali Chakraborty

“…Methods Using a pre-post intervention design, facility structural quality, providers’ training, practice, and knowledge on the provision of LARCs, and clients’ perceived service quality were assessed in 8 Ghanaian regions. …”
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Estimation of the economic impact of lumpy skin disease (LSD) outbreaks (2022–23) in dairy cattle farmers of Uttar Pradesh, India by Vinodhkumar Obli Rajendran, G. Govindaraj, A. Arivazhagan, D. Premkumar, Varsha Jayakumar, B.C. Saravanan, S. Nandi, Sanjay Panday, B.R. Singh

“…To estimate the economic loss in dairy animals due to LSD outbreaks, a study was conducted in 13 districts of Uttar Pradesh (UP) involving 248 farmers during 2022–2023. A semi-structured questionnaire was used to collect information about the outbreaks and economic losses incurred. …”
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Neuroprotection effect of HSV-1 LAT-derived miR-H2 and miR-H3 associated with Tau and alpha-synuclein downregulation by Fatemeh Saadatpour, Zahra Fekrirad, S. Mohammadhadi Mirab, Pedram Mardani, Ehsan Arefian

“…Future studies investigating the neuroprotective properties of HSV-1 miRNAs, particularly their impact on multi-structural peptide deficiencies, will offer valuable insights into HSV-1–host co-evolution and mechanisms for counteracting neuronal apoptosis. …”
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FACTORS ASSOCIATED WITH ANXIETY AND DEPRESSION SPECTRUM DISORDERS IN BEHCHET’S DISEASE by P. S. Ovcharov, T. A. Lisitsyna, D. Yu. Veltishchev, O. F. Seravina, O. B. Kovalevskaya, S. I. Glukhova, Z. S. Alekberova, E. L. Nasonov

“…ADSDs were diagnosed by a psychiatrist according to the ICD-10 during semi-structured interviews using the Hospital Anxiety and Depression Scale (HADS), the Hamilton Anxiety Rating Scale (HAM-A), and the Montgomery-Asberg Depression Rating Scale (MADRS). …”
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Schema-Informed Digital Mental Health Intervention for Maladaptive Cognitive-Emotional Patterns: Randomized Controlled Trial by Seohyun Jeong, Hyeonseong Kim, Silvia Kyungjin Lho, Inae Hwang, Seongjun Mun, Soohyun Kim, Hyejin Lim, Hyeonhee Kim, Min-Sup Shin, Woori Moon

“…These findings suggest the potential utility of structured, accessible digital interventions within stepped-care models for mental health support. …”
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Prostatectomy outcomes for patients with benign prostatic hyperplasia and its associated factors in East and West Gojjam zones comprehensive specialized hospitals, Northwest Ethiop... by Abebe Dilie Afenigus, Berhanu Kassahun, Megbar Dessalegn, Asmamaw Getnet, Mihretie Gedfew, Tiringo Kebede

“…Besides this, logistic regression models were computed to assess the relationship between variables. …”
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Prevalence and associated factors of HIV among female sex workers in Eastern and Southern Africa: Systematic review and meta-analysis. by Tigabu Kidie Tesfie, Getaneh Awoke Yismaw, Bantie Getnet Yirsaw, Habtamu Wagnew Abuhay, Meron Asmamaw Alemayehu, Nebiyu Mekonnen Derseh, Gebrie Getu Alemu, Muluken Chanie Agimas

“…<h4>Background</h4>Female sex workers (FSWs) are marginalized groups of the population who have limited access to healthcare and a higher risk of HIV infection due to biobehavioral and structural risk factors. Although it is known that the Eastern and Southern African region is affected by the highest HIV incidence and prevalence, understanding the burden among FSWs in the region remains limited. …”
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