Unfolding insights about resilience and its coping strategies by medical academics and healthcare professionals at their workplaces: a thematic qualitative analysis by Salman Yousuf Guraya, Jacqueline Maria Dias, Mohamed Ahmed Eladl, Ayah Mohammad Rajai Rustom, Fatima Audi Saleem Alalawi, Majid Hassan Saleh Alhammadi, Yusra Ahmed Mohammed Ahmed, Amna Ali Omran Taryam Al Shamsi, Sarah Juman Bilalaga, Alfred Nicholson, Hani Malik, Shaista Salman Guraya

“…Lastly, we adopted the Braun and Clarke 6-stage thematic model for qualitative data analysis. Results Our study recorded insights of 170 participants; 69 MHAs and 101 HCPs. …”
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Temperature-Dependent Aggregation of Tau Protein Is Attenuated by Native PLGA Nanoparticles Under in vitro Conditions by Paul PS, Rathnam M, Khalili A, Cortez LM, Srinivasan M, Planel E, Cho JY, Wille H, Sim VL, Mok SA, Kar S

“…In this study we evaluated the effects of FDA-approved poly (D,L-lactide-co-glycolic) acid (PLGA) nanoparticles, which can inhibit amyloid-β aggregation/toxicity in cellular/animal models of AD, on temperature-dependent aggregation of 0N4R tau isoforms in vitro.Methods: We have used a variety of biophysical (Thioflavin T kinetics, dynamic light scattering and asymmetric-flow field-flow fractionation), structural (fluorescence imaging and transmission electron microscopy) and biochemical (Filter-trap assay and detection of soluble protein) approaches, to evaluate the effects of native PLGA nanoparticles on the temperature-dependent tau aggregation.Results: Our results show that the aggregation propensity of 0N4R tau increases significantly in a dose-dependent manner with a rise in temperature from 27°C to 40°C, as measured by lag time and aggregation rate. …”
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Healthcare leadership practice and associated factors among primary healthcare managers in East Gojam Zone, Northwest Ethiopia: a mixed method study by Endalew Minwuye Andargie, Wubshet D. Negash, Abebe Kassa Geto, Asmamaw Atnafu

“…Method Facility-based cross-sectional study supplemented with qualitative inquiry was conducted in the East Gojam zone among 532 primary healthcare managers selected by a two-stage stratified random sampling technique. A pre-tested and structured self-administered questionnaire was used to collect the quantitative data. …”
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Incidence, bacteriological profile and predictors of surgical site infections following limb amputation at Bugando medical centre and Sekou toure referral regional hospital, Mwanza... by Haitham Hamudu, Helmut Nyawale, Vitus Silago, Mariam M. Mirambo, Phillipo L. Chalya, Stephen E. Mshana

“…Methods The longitudinal study was conducted among patients undergoing limb amputations between March and July 2024 at BMC and SRRH. Pre-tested structured questionnaires were used to collect sociodemographic and clinical data. …”
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Embracing innovation to drive positive change to clinical practice in stroke care by Indira Natarajan

“…The NMES device stimulates nerves in the leg to activate calf and foot muscle pumps, increasing venous blood flow in the deep veins, significantly reducing VTE incidence, with no cases reported in the NMES-treated group.The successful adoption of this technology was facilitated through leadership and a structured, multidisciplinary approach involving key stakeholders. …”
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Self-Management Practice of Minor Pregnancy Disorders and Associated Factors Among Pregnant Women Attending Antenatal Clinics at Tulu Bolo General Hospital, Ethiopia by Mangistu Abera MSc, Aynalem Belay MSc, Aberash Beyene Derribow MSc, Girma Bacha MSc, Sena Belina PhD

“…Among 403, pregnant women were selected using a systematic random sampling technique. A structured and interviewer-administered questionnaire was used to collect the data. …”
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Synthesis, Characterization, and Regeneration of Ag/TiO₂ Nanoparticles: Photocatalytic Removal of Mixed Dye Pollutants by Zainab S. Mahdi, Aseel M. Aljeboree, Fadhil A. Rasen, Noor Abd Alkhudhur Salman, Ayad F. Alkaim

“…The prepared samples were dried overnight at <inline-formula><math xmlns="http://www.w3.org/1998/Math/MathML" display="inline"><semantics><mrow><mn>60</mn><msup><mtext> </mtext><mo>∘</mo></msup><mi mathvariant="normal">C</mi></mrow></semantics></math></inline-formula> and then calcined at <inline-formula><math xmlns="http://www.w3.org/1998/Math/MathML" display="inline"><semantics><mrow><mn>500</mn><msup><mtext> </mtext><mo>∘</mo></msup><mi mathvariant="normal">C</mi></mrow></semantics></math></inline-formula> for 2 h. Structural and morphological characterization were carried out using X-ray diffraction, field emission scanning electron microscopy (FE-SEM), and transmission electron microscopy (TEM). …”
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The relationship between eHealth literacy and oral frailty among older adults: the serial mediating effects of self-efficacy and oral health by Jie Wu, Xin-xin Wang, Min Xu, Kang-ping Liu, Li-ling Xu, Ying Zhang

“…Spearman’s correlation analysis was conducted to examine the relationships among these variables. A structural equation model was used to analyse the mediating effects. …”
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Catastrophic health expenditure and associated factors among adult diabetes patients at the University of Gondar Comprehensive Specialized Hospital, Northwest Ethiopia by Kibret Mesgie, Asmamaw Atnafu, Tesfahun Zemene Tafere, Nigusu Worku, Banchlay Addis, Asebe Hagos

“…Data were collected using a structured questionnaire, entered into Epi-Data version 4.6, and analyzed using STATA version-16. …”
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New Insights into the Role of Inflammatory Pathways and Immune Cell Infiltration in Sleep Deprivation-Induced Atrial Fibrillation: An Integrated Bioinformatics and Experimental Stu... by Liang J, Tang B, Shen J, Rejiepu M, Guo Y, Wang X, Shao S, Guo F, Wang Q, Zhang L

“…Live studies have demonstrated that SD amplifies the atrial electrical rearrangement, structural changes, the infiltration of inflammatory cells, and the heightened presence of YBX1 along with inflammasome elements.Conclusion: The research pinpoints YBX1 as a crucial gene in SD-related AF, possibly influencing its impact via the NOD-like receptor signaling route and the invasion of immune cells. …”
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AQP5 trafficking is regulated by its C-terminal tail and interaction with prolactin-inducible protein by Claudia D’Agostino, Egor Zindy, Louise Conrard, Amel Takkal, Françoise Gregoire, Nargis Bolaky, Susanna Törnroth-Horsefield, Jason Perret, Christine Delporte

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Integrative development of a concise screening questionnaire for early detection of pregnant women at risk for dystrophy by Yadi Zhang, Xiaoge Gao, Haiyan Zhu, Qi Zhou, Xiaxia Cai, Pamela Ann Koch, Shengzhi Sun, Huanling Yu

“…Exploratory factor analysis was used to test the structural validity of the scale. A generalized linear model was used to analyze the correlation between dietary behavior and birth weight. …”
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Global transcriptome modulation by xenobiotics: the role of alternative splicing in adaptive responses to chemical exposures by Andrew J. Annalora, Jacki L. Coburn, Antony Jozic, Patrick L. Iversen, Craig B. Marcus

“…Conclusions This study demonstrates how xenobiotic structural features influence gene expression and splicing, revealing splicing patterns that expand our understanding of transcriptome diversity and function. …”
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Enhancing learning in medical same-day emergency care (MSDEC): implementing a bite-sized teaching programme by Sadaf Sadaf, Nnamdi Emekekwue, Rachel Lai, Prajakta Pradhan

“…To address this, we implemented a structured bite-sized teaching programme aimed at enhancing clinical knowledge and confidence while promoting multidisciplinary learning. …”
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An Improved 2D Pose Estimation Algorithm for Extracting Phenotypic Parameters of Tomato Plants in Complex Backgrounds by Yawen Cheng, Ni Ren, Anqi Hu, Lingli Zhou, Chao Qi, Shuo Zhang, Qian Wu

“…However, segmentation-based methods are labor-intensive due to their requirement for extensive annotation during training, while object detection approaches exhibit limitations in capturing intricate structural features. To achieve real-time, efficient, and precise extraction of phenotypic traits of seedling tomatoes, a novel plant phenotyping approach based on 2D pose estimation was proposed. …”
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Awareness about cervical cancer and its socio-economic determinants among adults in Bangladesh: Results from a nationwide cross-sectional study. by Tariful Islam, Md Abdullah Saeed Khan, Mohammad Delwer Hossain Hawlader, Nur-E-Safa Meem, Fahima Nasrin Eva, Umme Kulsum Monisha, Mohammad Ali Hossain, Mohammad Hayatun Nabi

“…This cross-sectional study was conducted in Bangladesh to evaluate cervical cancer awareness among adults aged 18 years and above. A semi-structured questionnaire was designed for this research, keeping in mind the local sociocultural contexts. …”
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Knowledge, Attitude and Practice Regarding Thyroid Disorders in Pregnant Women: A Cross-Sectional Study in Guangdong, China by Han L, Jin J, Xu J, Wang H, Qin A, Chen J

“…Multivariate logistic regression analysis indicated that practice score (OR = 1.212, 95% CI: [1.136– 1.294], P &lt; 0.001) and age (OR = 1.069, 95% CI: [1.007– 1.135], P = 0.029) were protective factors directly associated with thyroid disease complicating pregnancy. The structural equation model (SEM) results showed a direct effect of knowledge on attitude (β = 0.434, P = 0.021) and of attitude on practice (β = 0.604, P = 0.012). …”
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Development and Validation of the Academic Self-Handicapping Scale for Nursing and Midwifery Students: A Study of Reliability and Agreement by Fatemeh Aliakbari Borovati, Naser Mohammadi Ahmadabadi, Shahrzad Sanjari, Alireza Keikha, Asma Bameri, Gholamhasan Panahi, Mohammadreza Mohamadi Soliemani

“…In the qualitative phase, 30 nursing and midwifery students were selected through purposive sampling, and semi-structured interviews were conducted to identify the dimensions of academic self-handicapping. …”
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Establishing a Multicenter Active Adverse Events Following Immunization Sentinel Surveillance Network Across 22 Tertiary Care Hospitals in India: Protocol for a Prospective Observa... by Apoorva Sharan, Manoja Kumar Das, Akhil PM, Ramesh Poluru, Neeraj Kumar Kashyap, Christian Burri, Jan Bonhoeffer, Satinder Aneja, Deepak Polpakara, Narendra Kumar Arora

“…We screened all children aged 1-24 months who were hospitalized for more than 24 hours at participating sites to identify suspected or confirmed cases of these outcomes using a structured checklist. Written informed consent was obtained from the parent or legally authorized representative for inclusion in the study. …”
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Hypothetical Preferences and Concerns for Long-Acting Injectable HIV PrEP Use Among Female Barmaids in Ubungo, Dar Es Salaam, Tanzania by Akyoo WO, Mosha IH, Mpembeni RM, Jahn A

“…Interviews were conducted using a guide with semi-structured questions. We adopted an inductive approach for analyzing data.Findings: The majority of PrEP non-users expressed no preference for any form of PrEP, while oral PrEP-users preferred LAI PrEP. …”
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