Effects of left ventricular hypertrophy on prognosis of kidney in patients with chronic kidney disease of stages 3～4 by XIAO Xiao-fen, WANG Xiao-qin, HAN Si-ping

“…Objective To analyze the distribution of left ventricular hypertrophy（LVH） and its effect on renal progression in patients with chronic kidney disease（CKD） of stages 3⁴.Methods We collected the baseline data of 61 patients with CKD stages of 3⁴ who were followed up in Nephrology outpatient of Hubei Provincial Hospital of TCM from February 2012 to February 2016,and found out the distribution of LVH.By following up regularly,we recorded the outcome events including serum creatinine（SCr） double,estimated glomerular filtration rate（eGFR）<15 ml·min^-1·（1.73m²）^-1or 50%reduction,renal replacement therapy or death.And we divided 61 cases into renal function progression group and non-progression group,compared the data between two groups,and used COX risk regression model to analyze risk factors on prognosis of kidney.Results The average follow-up time was（34.70±9.54） months.One case dropped out,and 22 cases entered outcome events,including 12 cases with SCr doubles/50%reduction of eGFR or <15 ml·min^-1·（1.73 m²）^-1,8 cases undergoing maintain hemodialysis and two deaths.The prevelence of left ventricular dilatation,LVH and left ventricular diastolic dysfunction in CKD stages 3⁴ was 22.95%,37.70%,and60.66%respectively.The differences in systolic blood pressure,SCr,eGFR,interventricular septum thickness（IVST）,left ventricular end-diastolic diameter（LVEDd）,left ventricular mass（LVM）,left ventricular mass index（LVMI） and rate of left ventricular enlargement and LVH were significant between renal function progression group and non-progression group（P<0.05）.COX single factor regression analysis showed that systolic blood pressure（P = 0.013）,LVM（P = 0.003）,LVMI（P =0.001）,left ventricular enlargement（P<0.001） and LVH（P = 0.009） could endanger the patients of CKD of stages 3⁴ into the end point events.Multivariate COX proportional hazards regression analysis（enter method） showed risk factors associated with renal function progression in patients of CKD of stages 3⁴ were systolic blood pressure（b=1.075,HR=2.931,P = 0.025）,LVH（b=1.319,HR= 3.740,P = 0.048）.Conclusions LVH was common observed in patients with CKD of stages 3⁴.Early paying attentions to cardiac ultrasound,and timely intervening and controlling blood pressure and structural abnormality of left ventricle are necessary.…”
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Predictors of Preterm Birth among Mothers Who Gave Birth in Silte Zone Public Hospitals, Southern Ethiopia by Jida Ali Hassen, Mengistu Nunemo Handiso, Bitiya Wossen Admassu

“…Data were collected using a structured interview questionnaire complement with record reviewing. …”
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Prevalence and determinants of poor glycemic control among diabetic chronic kidney disease patients on maintenance hemodialysis in Tanzania. by Emmanuel Arthur Mfundo, Alphonce Ignace Marealle, Goodluck G Nyondo, Martine A Manguzu, Deus Buma, Peter Kunambi, Ritah F Mutagonda

“…A consecutive sampling technique was used for patient recruitment, and a semi-structured questionnaire was used to collect data. The primary outcome was poor glycemic control were considered when glycated hemoglobin (HbA1c) levels were <  6% or > 8%. …”
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Importance of antenatal identification of small for gestational age fetuses on perinatal and childhood outcomes: A register‐based cohort study by Emma Hertting, Lotta Herling, Pelle G. Lindqvist, Eva Wiberg‐Itzel

“…Inclusion criteria: singleton pregnancies without chromosomal aberrations or structural abnormalities, with a gestational age at delivery between 22+0 and 43+0 (n = 48 843). …”
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Beyond the SAFE strategy: Systematic review and meta-analysis of prevalence and associated factors of active trachoma among children in Ethiopia. by Zufan Alamrie Asmare, Denekew Tenaw Anley, Melaku Ashagrie Belete, Anteneh Mengist Dessie, Melkamu Aderajew Zemene, Ermiyas Alemayehu, Natnael Moges, Natnael Kebede, Sintayehu Simie Tsega, Asaye Alamneh Gebeyehu, Rahel Mulatie Anteneh, Ermias Sisay Chanie

“…Therefore, it is imperative to fine-tune the intervention focus on personal hygiene-related activities in removing dirt, fly-eye contact, and a well-structured approach for both constructing and ensuring the functionality of household taps and latrines. …”
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Timing of exposure to household poverty and adolescent mental health problems by Y. Koyama, A. Isumi, T. Fujiwara

“…We applied g-estimation of structural nested mean modelling to account for time-varying confounders. …”
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Prevalence and Associated Factors of Anemia among Reproductive-Aged Women in Sayint Adjibar Town, Northeast Ethiopia: Community-Based Cross-Sectional Study by Berhanu Woldu, Bamlaku Enawgaw, Fikir Asrie, Elias Shiferaw, Zegeye Getaneh, Mulugeta Melku

“…Sociodemographic, socioeconomic, and reproductive histories of study participants were collected using the structured and pretested questionnaire. Capillary blood and stool samples were collected from each study participant for hemoglobin and parasitological analysis, respectively. …”
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In silico design and in vitro validation of a multi-epitope peptide vaccine targeting triple-negative breast cancer by Pengjun Zhou, Xing Shi, Jinquan Xia, Hong Hu

“…Five multi-epitope vaccine constructs were designed using different adjuvants (GM-CSF, β-defensin, IL-2, cholera enterotoxin, and 50S ribosomal protein L7/L12), and enhanced with PADRE and HEYGAEALERA sequences. Structural modelling, refinement, disulfide engineering, and validation (via Robetta, GalaxyRefine, ProSA, and Ramachandran plots) were performed, followed by docking with TLR2 and TLR4. …”
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Assessment of Poor Home Management Practice of Diarrhea and Associated Factors among Caregivers of Under-Five Years Children in Urban and Rural Residents of Doba Woreda, Ethiopia:... by Waktole Kebede Fufa, Gebretsadik Berhe Gebremedhin, Gebremedhin Berhe Gebregergs, Taklu Marama Mokonnon

“…An interviewer administered pretested structured questionnaire was used to collect data. Collected data were entered into Epi Info version 3.5.1 and exported to statistical package for social sciences (SPSS) version 20.0 for analysis. …”
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RTCi versus OSBC teaching method in eight-year medical program: a randomized, controlled educational research by Lu Wang, Ben Zhao, Xiaohui Wang, Minghao Guo, Lu Wang, Lei Dou, Yinan Sun

“…The two groups were compared in terms of on-schedule graduation, the number of papers published per student, grade-weighted scores and objective structured clinical examination (OSCE) scores. Results The 230 participants were randomly divided into two groups. …”
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Quantitative Analysis of Ginger Maturity and Pulsed Electric Field Thresholds: Effects on Microstructure and Juice’s Nutritional Profile by Zhong Han, Pan He, Yu-Huan Geng, Muhammad Faisal Manzoor, Xin-An Zeng, Suqlain Hassan, Muhammad Talha Afraz

“…This study used fresh (young) and old (mature) ginger tissues as model systems to investigate how plant maturity modulates the response to pulsed electric field (PEF), a non-thermal processing technology. …”
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Building linkages between private pharmacies and public facilities to improve diabetes and hypertension care in urban areas of Nepal: a protocol for implementation research by Grishu Shrestha, Deepak Joshi, Helen Elsey, Abhigyna Bhattarai, Parash Mani Sapkota, Bassey Ebenso, Raju Raman Neupane, Bryony Dawkins, Sampurna Kakchapati, Sujan Poudel, Shreeman Sharma, Abriti Arjyal, Sushil Chandra Baral

“…Qualitative data from semi-structured interviews with health workers at pharmacies, clients, and public health facility staff will be analyzed via thematic analysis to identify barriers to and facilitators of intervention adoption, implementation, and sustainability. …”
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Nurturing compassion in neonatal end-of-life care: a qualitative exploration of palliative care nurses’ roles and experiences by Osama Mohamed Elsayed Ramadan, Alaa Hussain Hafiz, Nouran Essam Katooa, Nasreen M. Alghamdi, Nadia Bassuoni Elsharkawy, Enas Mahrous Abdelaziz, Nermen Abdelftah Mohamed, Nagwa Ibrahim Mabrouk Baraka

“…Forty nurses from four neonatal intensive care units (NICUs) in Egypt completed semi-structured interviews and reflective journaling. Data were analyzed using a two-phase approach, incorporating Lazarus and Folkman’s Transactional Model of Stress and Coping to contextualize findings within broader emotional regulation and resilience frameworks. …”
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Usefulness of Mixed Reality in Surgical Treatment: Delphi Study by Renato Magalhães, Ana Carolina Lima, António Marques, Javier Pereira, Lúcio Lara Santos

“…In the first round, participants provided insights into the potential applications of MR in surgical procedures through open-ended questions structured across 5 distinct sections. Responses were analyzed to develop the second-round questionnaire, which was hierarchically organized into main topics and subtopics. …”
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Protein intake and muscle mass of community-dwelling older adults: a cross-sectional study in Kigali, Rwanda by Theogene Habumugisha, Eric Matsiko, Inger Elisabeth Måren, Matthias Kaiser, Alida Melse-Boonstra, Karin Borgonjen-van den Berg, Jutta Dierkes, Ingunn M. S. Engebretsen

“…Dietary intake was estimated using two non-consecutive 24-h recalls. A structured questionnaire was used to collect data on socio-demographic characteristics. …”
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Association of oral health status and salivary profile of rheumatoid arthritis disease subjects and healthy subjects and prediction of caries risk using cariogram- A cross-sectiona... by Ananya Jha, Aparna K S, Praveen Jodalli, Avinash B R

“…Methods: A total of ninety volunteers were enrolled, forty-seven of whom were age-matched healthy individuals and forty-three of whom were patients with rheumatoid arthritis. A structured questionnaire, clinical assessment, and saliva collection were used in the data gathering process. …”
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Risk stratification and clinical classification for postoperative neurological complications in post-tuberculosis kyphosis: a retrospective cohort study by Jianqiang Wang, Yong Hai, Haoshuang Geng, Zhangfu Li, Yuzeng Liu, Yangpu Zhang, Lijin Zhou

“…The area under the curve (AUC) for both classifications demonstrated good predictive performance, with the DeLong test indicating superior efficacy for the Imaging-Biomarker Classification (P = 0.039). Conclusion Spinal structural instability, spinal cord compression, osteotomy grade, and elevated CRP levels may all contribute to an increased risk of postoperative neurological complications in patients with post-tuberculosis kyphosis. …”
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The role of social relationships in recovery court programs by Emma Katherine Dudley, Barbara Andraka-Christou, Alexandra Boland, Danielle N. Atkins, Ekaterina Pivovarova

“…Methods We used in-depth, semi-structured qualitative interviews with recovery court participants (N = 68) across nine recovery courts in one northeastern state to explore the role of social relationships on recovery court program progress. …”
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Educating tomorrow's donors: a high school initiative to promote blood and stem cell donation through stem education by Katia Mareschi, Alessia Giovanna Santa Banche Niclot, Elena Marini, Camilla Francesca Proto, Federico Divincenzo, Claudia Peirolo, Giulia Zucchetti, Franca Fagioli

“…Conclusions The program effectively promoted awareness of blood and stem cell donation among adolescents and stimulated interest in STEM-related careers. Given its structured and adaptable format, this model could be implemented in other educational contexts to enhance health literacy and support donor recruitment efforts. …”
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Analysis of the Carbon Footprint of a Textile Company for the Automotive Industry by Beatriz Silva, David Malheiro, Dinis Júnior, Francisca Nunes, Joana Santos, Liliana Guimarães, Maria Socorro, Mariana Carvalho, Mariana Silva, Rui M. Lima, Rui M. Sousa

“…This study aims to develop a process to calculate the carbon footprint of a company in the textile sector for the automotive industry, thus addressing a research gap identified in this sector. Based on a structured calculation model, the project aspires to innovate by quantifying not only the greenhouse gas emissions at different stages of the company’s operations, including those generated by the consumed electricity and gas, but also the emissions related to external and in-house transportation and solid waste management. …”
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