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  1. 57521
  2. 57522

    Targeting macrophages and ion homeostasis in T2D: new genes and therapeutic pathways identified by Lisha Mou, Lisha Mou, Tony Bowei Wang, Ying Lu, Ying Lu, Zijing Wu, Zijing Wu, Yuxian Chen, Ziqi Luo, Xinyu Wang, Zuhui Pu, Zuhui Pu

    Published 2025-08-01
    “…These DEGs were intersected with ABRGs to identify hub genes. Machine learning models were developed to predict T2D, and structural predictions of the hub proteins were performed. …”
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    Article
  3. 57523

    Improving contraceptive agency through peer social support: findings from a longitudinal qualitative evaluation of the I-CAN intervention in Uganda by Erica Sedlander, Beth Phillips, Isabelle Thapar, Catherine Birabwa, Lauren Suchman, Madeline Griffith, Dinah Amongin, Ronald Wasswa, Lynn Atuyambe, Jenny Liu, Peter Waiswa, Kelsey Holt

    Published 2025-05-01
    “…Peer social support shows promise to address structural and social barriers limiting women's agency to make and act on decisions related to contraception, but evidence-based models are lacking. …”
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  4. 57524

    The circUbqln1, regulated by XBP1s, interplays with 14–3–3ζ to inhibit collagen synthesis and promote osteoarthritis by controlling PRODH activity and proline metabolism by Naibo Feng, Yuanlan Ye, Yiming Pan, Biao Kuang, Yu Du, Nana Geng, Cheng Chen, Kaiwen Liu, Li Liang, Menglin Xian, Yuyou Yang, Xingyue Li, Lin Deng, Fengmei Zhang, Liang Kuang, Mengtian Fan, Yangli Xie, Fengjin Guo

    Published 2024-12-01
    “…Consequently, this leads to the promotion of proline degradation and the inhibition of collagen synthesis,ultimately culminating in the impairment of cartilage and its structural integrity. Conclusion: CircUbqln1 plays a crucial role in the occurrence and development of OA, indicating that the inhibition of circUbqln1 holds promise as a significant approach for treating OA in the future.…”
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  5. 57525

    Investigating the efficiency of fixed bed column containing Fe3O4-ZIF8@eggshell membrane matrix in concurrent adsorption of arsenic and nitrate from water by Hossein Abdipour, Ghorban Asgari, Abdolmotaleb Seid-Mohammadi, Alireza Rahmani, Reza Shokoohi

    Published 2024-12-01
    “…This study demonstrates the stability and high efficiency of the newly structured adsorbent after 10 consecutive adsorption cycles. …”
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  6. 57526

    Family-based substance use screening and intervention for adolescents with chronic medical conditions: a study protocol to implement SBIRT-family within school-based health centers by Faith Summersett Williams, Natalie A. Larez, Lauren Mondesir, Kennedy Curtis, Sara Valdivia, Sara Becker, Kenneth Papineau, Aaron Hogue

    Published 2025-06-01
    “…Focus groups will be audio recorded and conducted in English. The semi-structured focus group guides were designed based on the Health Equity Implementation Framework (HEIF) and the Consolidated Framework for Implementation Research (CFIR). …”
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    Article
  7. 57527

    Two zinc ABC transporters contribute to Rhizobium leguminosarum symbiosis with Pisum sativum and Lens culinaris by Joanna N. Soldek, Marta Ballesteros-Gutiérrez, Laura Díaz-Sáez, Ignacio Delgado-Santamaría, José Manuel Palacios, José Manuel Palacios, Marta Albareda, Marta Albareda

    Published 2025-06-01
    “…In this work, protein sequence analysis and structural modelling have revealed that RLV_3444 is highly similar to the functionally characterized zinc-binding protein ZniA from Klebsiella pneumoniae, so the host-dependent binding protein was renamed as ZniA and the transporter system as ZniCBA. …”
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    Article
  8. 57528

    Association of wearable device-measured physical activity with full-course diabetic retinopathy and retinal traits: insights from the middle-aged and older adult cohort by Chenxiao Shen, Zijing Du, Chunran Lai, Ting Su, Qiaowei Wu, Yanlei Chen, Ying Fang, Zhuoting Zhu, Xiayin Zhang, Honghua Yu

    Published 2025-06-01
    “…Abstract Purpose To assess accelerometer-measured physical activity (PA) in patients with all stages of diabetic retinopathy (DR) and investigate its association with specific retinal structural metrics. Methods This extensive cohort study included 13,600 participants with an average age of 56.39 years. …”
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    Article
  9. 57529

    Validation of the European Oncology toolkit for the self-assessment of Quality of Life (EUonQoL-Kit) in cancer patients and survivors: study protocol of a pan European survey by G. Apolone, M. Costantini, L. Caselli, N. Bos, A. Caraceni, G. Ciliberto, N. Couespel, M. Ferrer, M. Groenvold, S. Kaasa, C. Lombardo, R. Pietrobon, G. Pravettoni, A. Sirven, H. Vachon, G. Velikova, O. Garin, A. Gilbert, A. Machiavelli, C. Marzorati, R. Miceli, M. Pe, MA. Petersen, A. Tanzilli, F. van Schelven, C. Dantas, I Minnée-van Braak, L. Pinnavaia, C. Brunelli

    Published 2024-12-01
    “…Psychometric analyses will encompass exploratory and confirmatory factor analyses (measurement model and structural validity), Cronbach's alpha (internal consistency), intraclass correlation coefficient (test–retest reliability), Pearson/Spearman correlation (concurrent validity), comparison of group scores (construct validity), and Differential Item Functioning (cross-country item equivalence). …”
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  10. 57530

    Lateral bearing characteristics of subsea wellhead assembly in the hydrate trial production engineering by Jing Zeng, Wen-wei Xie, Bei-bei Kou, Jing-an Lu, Xing-chen Li, De-jun Cai, Hao-xian Shi, Ke-wei Zhang, Hua-qing Liu, Jin Li, Bo Li

    Published 2023-07-01
    “…However, the deformation law of the deep-water suction anchor wellhead assembly under the moving load of the riser is not clear, and it is necessary to understand the lateral bearing characteristics to guide the design of its structural scheme. Based on 3D solid finite element method, the solid finite element model of the suction anchor wellhead assembly is established. …”
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    Article
  11. 57531

    Energy-Efficient Office Renovation by Minyoung KWON

    Published 2020-01-01
    “…The empirical studies are structured in four parts. Energy consumption As a preliminary study, architects and facility managers were interviewed to identify the building characteristics of renovated offices and energy consumption. …”
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    Article
  12. 57532

    Factors affecting the design of the management dashboard framework with an emphasis on the components of human resources productivity by Hassan Barmaki, Farshad Faezy Razi, Ehtesham Rashidi

    Published 2024-11-01
    “…The statistical population of the research includes 15 senior managers of Mapna Company and knowledgeable academic staff members in the field of research; and the interviews continued until reaching theoretical saturation. Semi-structured interviews were used to collect information. …”
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  13. 57533

    Silver nanoparticles (Ag-NPs) embedded in zeolite framework: A comprehensive study on bromide removal from water, including characterization, antibacterial properties, and adsorpti... by Aiman Eid Al-Rawajfeh, Albara Ibrahim Alrawashdeh, Mohammad Taha Etiwi, Ali Alnawaiseh, Muhammad Kashif Shahid, Mohanad H.M. Masad, Sumaia Omar Oran, Solhe F. Alshahateet

    Published 2024-01-01
    “…Fourier Transform Infrared Spectroscopy (FT-IR) and X-ray Diffraction (XRD) analyses confirmed the successful integration of Ag-NPs within the zeolite framework, ensuring structural integrity and chemical composition. Under varying operational conditions, the batch experiments consistently exhibited the zeolite with Ag-NPs as superior in bromide removal efficacy compared to zeolite alone, both achieving over 96% removal efficiency. …”
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  14. 57534

    Consensus-Based Guidelines for Best Practices in the Selection and Use of Examination Gloves in Healthcare Settings by Jorge Freitas, Alexandre Lomba, Samuel Sousa, Viviana Gonçalves, Paulo Brois, Esmeralda Nunes, Isabel Veloso, David Peres, Paulo Alves

    Published 2025-01-01
    “…Recommendations were structured to ensure compliance with international regulations and sustainability frameworks aligned with the One Health approach and Sustainable Development Goals (SDGs). …”
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  15. 57535

    Increased vulnerability to psychological distress and suicidal ideation among transgender women with self-reported disabilities in San Francisco, California by Abtin Shafie, Alexis Salvatore, Riley Shea, Eileen Yu, Oyku Ozyucel, Ansharan Akbar, Bow Suprasert, Erin C. Wilson, Willi McFarland, Kelly D. Taylor, Sean Arayasirikul

    Published 2025-06-01
    “…OBJECTIVE: Research among transgender women has found health, but especially mental health, to be shaped by social inequities and multiple, intersectional, structural vulnerabilities. While some studies have shown that transgender adults are also more likely to have a disability than cisgender adults, few studies have explored this intersection. …”
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  16. 57536

    Linking Medical Treatment and Physiotherapy in Stroke Recovery: A Meta-Analytical Statistical Synthesis by Abeer Mohammed, Mohamed Elfar, Amira Afify, Heba Gaber, Mohamed Raafat, Kholoud Soliman, Amash Alajmi, Ahmad Quneis, Forat Alomoush, Kalmah AL-Olimat, Shorooq Almaaitah, Yazeed Hijazi, Asma Atwa, Ahmed Alja'fari, Wessam Mohamed

    Published 2025-04-01
    “…The study underscores the importance of early, structured physiotherapy within multidisciplinary care models and provides statistically grounded insights to inform stroke rehabilitation protocols. …”
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    Article
  17. 57537

    Evaluation of a train-the-coach program in the context of a complex intervention for diabetes type 2 and coronary heart disease patients (P-SUP study) by Isabel Hamm, Aliza Lehmann, Angeli Gawlik, Yeliz Nacak, Julia Timmke, Christian Funke, Stefan Wilm, Lisa Giesen, Marcus Redaèlli, Chloé Chermette, Frank Vitinius, Frank Vitinius

    Published 2025-07-01
    “…The training was evaluated based on the Kirkpatrick model, quantitatively with an evaluation survey and a knowledge test on a 7-point Likert scale and qualitatively semi-structured interviews, with emphasis on the qualitative evaluation. …”
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    Article
  18. 57538

    Ubiquitin-specific protease 38 exacerbates diabetic cardiomyopathy via post-translational modification of ACAD11 by Zheng Xiao, Yucheng Pan, Hong Meng, Zongze Qu, Liang Guo, Bin Kong, Wei Shuai, He Huang

    Published 2025-07-01
    “…Conversely, cardiomyocyte-specific USP38 deletion improved cardiac structural and electrical remodeling and attenuated mitochondrial impairment. …”
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    Article
  19. 57539

    Self-assembled supramolecular nanogels based on poly(vinyl alcohol) and gallic acid as nanocarriers for breast cancer treatment by Anabella P. Rosso, Micaela A. Macchione, Ana C. Racca, Matias L. Picchio, Eduardo A. Coronado, Marisa Martinelli, Sergio D. Garcia Schejtman

    Published 2025-07-01
    “…This behavior is attributed to the particle formation kinetics, leading to different structural arrangements. The different nano/microgels synthesized were characterized using DLS, TEM, FT-IR, and NMR. …”
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  20. 57540