Experiences and perceptions of Chinese patients enrolled in a clinical trial assessing tuina and manual therapies for knee osteoarthritis: a nested qualitative study by Luping Liu, Lingyun Zhang, Sina Li, Meiling Cai, Siyu Han, Zhiwen Weng, Qianji Chen, Yixuan Gao, Xiaoming Yang, Yang Zhang, Duoduo Li, Changxin Liu, Ya’nan Sun, Xiyou Wang, Changhe Yu

“…The interviews were conducted by two researchers who have extensive experience interviewing KOA patients, and data were gathered through face-to-face, semi-structured interviews to ensure a high level of information power. …”
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Unique epitope–antibody interactions in the intrinsically disordered proteoglycan-like domain of human carbonic anhydrase IX defined by high-resolution NMR combined with yeast surf... by Feng Ni, Cunle Wu, Ping Xu, Ping Wang, Yves Fortin, Melanie Arbour, Luke Masson, Denis L’Abbé, Andrea Acel, Mylene Gosselin, Anne E.G. Lenferink

“…Transverse relaxation optimized NMR spectroscopy of 11H9-F(Ab) in complex with the CA-IX IDR outlines structural rigidification of a linear epitope, while the rest of the IDR remains largely unstructured upon complex formation. …”
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A Multidata Approach to Open Clusters: Roslund 3 and Ruprecht 174 in CCD UBV and Gaia DR3 Context by Hülya Karagöz, Talar Yontan, Selçuk Bilir, Olcay Plevne, Tansel Ak, Serap Ak, Remziye Canbay, Timothy Banks

“…A detailed analysis of the structural, astrophysical, kinematic, and dynamical properties of the open clusters Roslund 3 and Ruprecht 174 is carried out using CCD UBV photometry in conjunction with astrometric and photometric data from Gaia DR3. …”
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Fostering achievement of sustainable development goals through green culture and digital transformation: Empirical evidence from an Indonesian education human resources university by Indah Prabawati, Wiwik Sri Utami, Harmanto, Meirinawati, Suci Megawati, Artanti Indrasetianingsih, Sud Sudirman

“…Utilizing a quantitative approach, a survey was conducted with 435 students from State University of Surabaya, a leading IEHRU. Data were analyzed using partial least squares structural equation modeling (PLS-SEM) with SmartPLS 4. …”
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Quantitative Characterization and Determination of the Main Factors That Control Fracture Development in the Lower Paleozoic Shale in Southeastern Chongqing, China by Zhiping Zhang, Xiangye Kong, Qing Chen, Ye Zhang, Zhi Deng, Chuan Yu, Zhian Lei, Haijie Zhang, Xiaofeng Wang, Guanghua Yao, Licheng Yang, Xianfeng Tan

“…The results obtained showed that there are three types of fractures in the lower Paleozoic shale in southeastern Chongqing, which are structural, diagenetic, and abnormal high-pressure fractures. …”
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Astragaloside IV attenuates podocyte apoptosis via regulating TXNIP/NLRP3/GSDMD signaling pathway in diabetic nephropathy by Zhibo Hu, Yu Zhou, Cailing Gao, Junfen Liu, Congqing Pan, Jun Guo

“…Conclusions The anti-pyroptosis effect of AS-IV via the TXNIP-NLRP3-GSDMD axis improves the renal function and podocyte damage of db/db mice and delays the onset of DKD, according to in vivo and in vitro experimental data.…”
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Effects of timely case conferencing between general practitioners and specialist palliative care services on symptom burden in patients with advanced chronic disease: results of th... by Tina Mallon, Josefine Schulze, Nadine Pohontsch, Thomas Asendorf, Jan Weber, Silke Böttcher, Uta Sekanina, Franziska Schade, Nils Schneider, Judith Dams, Michael Freitag, Christiane Müller, Friedemann Nauck, Tim Friede, Martin Scherer, Gabriella Marx

“…Methods The cluster-randomised controlled trial compared a structured palliative care nurse visit followed by an interprofessional case conference to usual care. …”
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Adherence to Life’s Essential 8 enhances gut microbiota diversity and cognitive performance by Yannick N. Wadop, Jazmyn Muhammad, Rebecca Bernal, Claudia L. Satizabal, Claudia L. Satizabal, Claudia L. Satizabal, Claudia L. Satizabal, Alexa Beiser, Alexa Beiser, Alexa Beiser, Ramachandran S. Vasan, Ramachandran S. Vasan, Ramachandran S. Vasan, Ramachandran S. Vasan, Ramachandran S. Vasan, Ramachandran S. Vasan, Ramachandran S. Vasan, Ramnik Xavier, Ramnik Xavier, Ramnik Xavier, Tiffany Kautz, Tiffany Kautz, Sudha Seshadri, Sudha Seshadri, Sudha Seshadri, Sudha Seshadri, Jayandra Jung Himali, Jayandra Jung Himali, Jayandra Jung Himali, Jayandra Jung Himali, Jayandra Jung Himali, Jayandra Jung Himali, Bernard Fongang, Bernard Fongang, Bernard Fongang

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The microbiologist's guide to metaproteomics by Tim Van Den Bossche, Jean Armengaud, Dirk Benndorf, Jose Alfredo Blakeley‐Ruiz, Madita Brauer, Kai Cheng, Marybeth Creskey, Daniel Figeys, Lucia Grenga, Timothy J. Griffin, Céline Henry, Robert L. Hettich, Tanja Holstein, Pratik D. Jagtap, Nico Jehmlich, Jonghyun Kim, Manuel Kleiner, Benoit J. Kunath, Xuxa Malliet, Lennart Martens, Subina Mehta, Bart Mesuere, Zhibin Ning, Alessandro Tanca, Sergio Uzzau, Pieter Verschaffelt, Jing Wang, Paul Wilmes, Xu Zhang, Xin Zhang, Leyuan Li, The Metaproteomics Initiative

“…As the primary catalytic and structural components of microbiomes, proteins provide unique insights into the active processes and ecological roles of microbial communities. …”
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Genomic landscape of diffuse glioma revealed by whole genome sequencing by Ben Kinnersley, Josephine Jung, Alex J. Cornish, Daniel Chubb, Ross Laxton, Anna Frangou, Andreas J. Gruber, Amit Sud, Giulio Caravagna, Andrea Sottoriva, David C. Wedge, Thomas Booth, Safa Al-Sarraj, Samuel E. D. Lawrence, Erminia Albanese, Giulio Anichini, David Baxter, Alexandros Boukas, Yasir A. Chowdhury, Pietro D’Urso, Robert Corns, Andrew Dapaah, Ellie Edlmann, Fay Greenway, Paul Grundy, Ciaran S. Hill, Michael D. Jenkinson, Sandhya Trichinopoly Krishna, Stuart Smith, Susruta Manivannan, Andrew J. Martin, Samir Matloob, Soumya Mukherjee, Kevin O’Neill, Puneet Plaha, Jonathan Pollock, Stephen Price, Ola Rominiyi, Bobby Sachdev, Fozia Saeed, Saurabh Sinha, Lewis Thorne, Ismail Ughratdar, Peter Whitfield, Amir Saam Youshani, Helen Bulbeck, Prabhu Arumugam, Richard Houlston, Keyoumars Ashkan

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Humoral and cellular response to SARS-CoV-2 mRNA vaccine in paediatric heart transplant recipients by Amanda Bermejo-Gómez, Laura Tarancon-Diez, Beatriz Lazaro-Martin, Begoña Santiago-Garcia, Nuria Gil Villanueva, Roberto Alonso, Mª Ángeles Muñoz-Fernández, Manuela Camino López, Alicia Hernanz-Lobo, María Luisa Navarro Gómez

“…The T-lymphocyte phenotype and SARS-CoV2-specific CD4+ and CD8+ T-cell response was studied by multiparametric flow cytometry through peripheral blood mononuclear cells by the quantification of degranulation markers (CD107a) and intracellular cytokines (IFN-γ, TNF-α and IL-2) after in vitro stimulation with SARS-CoV-2 peptides from structural proteins (S, M, N, E) and non-structural viral proteins. …”
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Faster efficacy and reduced nodule occurrence with PLLA (poly-l-lactic acid) porous microspheres by Qihua Cao, Qihua Cao, Qihua Cao, Jiayu Chen, Jiayu Chen, Jiayu Chen, Jiayu Chen, Zijun Zhang, Yufei Xiong, Jinxia Ma, Wei Sun, Xin Chen, Qilei Lou, Kaijia Tang, Kaijia Tang, Kaijia Tang, Kaijia Tang, Feng Lin, Feng Lin, Feng Lin, Yueliang Zhu, Yueliang Zhu, Yueliang Zhu, Xiaohua Yu, Xiaohua Yu, Xiaohua Yu, Xiaohua Yu

“…Post-euthanasia, tissue sections underwent histological examination through hematoxylin and eosin (H&E) staining and Masson’s trichrome technique, with subsequent statistical analysis of the observational data.ResultsThe PLLA porous microsphere group demonstrated significantly faster onset of action compared to the control, with observable collagen deposition as early as week 2, enhanced inflammatory cell infiltration, more homogeneous tissue distribution, and substantially fewer microaggregates upon histological examination.DiscussionStructural modification of PLLA microspheres has successfully accelerated their onset of action while reducing nodule formation, thereby providing novel insights for clinical applications.…”
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An open-source simulation platform to support and foster research collaboration in natural hazards engineering by Adam Zsarnóczay, Gregory G. Deierlein, Frank McKenna, Matthew Schoettler, Sang-Ri Yi, Barbaros Cetiner, Aakash Bangalore Satish, Jinyan Zhao, Justin Bonus, Abiy F. Melaku, Sina Naeimi, Pedro Arduino, Rachel Davidson, Rachel Davidson, Catherine Gorle, Sanjay Govindjee, Ahsan Kareem, Tracy L. Kijewski-Correa, Tracy L. Kijewski-Correa, Laura N. Lowes, Michael Motley, Seymour M. J. Spence, Ertugrul Taciroglu, Alexandros A. Taflanidis, Matthew DeJong

“…This paper presents the conceptual foundation and current capabilities of the SimCenter platform, covering hazard characterization, structural response analysis, damage and loss estimation, and recovery modeling. …”
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Signatures of omicron-like adaptation in early SARS-CoV-2 variants and chronic infection by Mark Tsz Kin Cheng, Mazharul Altaf, Jesu Castin, Ann-Kathrin Reuschl, Benjamin L. Sievers, Kimia Kamelian, Dejan Mesner, Rebecca B. Morse, Adam Abdullahi, Bo Meng, Kata Csiba, Steven A. Kemp, Darren P. Martin, Clare Jolly, Christopher Ruis, Lipi Thukral, Ravindra K. Gupta

“…These data shed light on the balance between SARS-CoV-2 upper airway adaptation/immune evasion, syncytium formation, and pathogenic potential.…”
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Newly diagnosed diseases and the frequency of their occurrence in patients after a new coronavirus infection. Results of an International Register "Dynamics Analysis of Comorbiditi... by G. P. Arutyunov, E. I. Tarlovskaya, A. G. Arutyunov, D. S. Polyakov, Yu. N. Belenkov, A. O. Konradi, Yu. M. Lopatin, A. P. Rebrov, S. N. Tereshchenko, A. I. Chesnikova, H. G. Hayrapetyan, A. P. Babin, I. G. Bakulin, N. V. Bakulina, L. A. Balykova, A. S. Blagonravova, M. V. Boldina, M. I. Butomo, A. R. Vaisberg, A. S. Galyavich, V. V. Gomonova, N. Yu. Grigoryeva, I. V. Gubareva, I. V. Demko, A. V. Evzerikhina, A. V. Zharkov, A. A. Zateishchikova, U. K. Kamilova, Z. F. Kim, T. Yu. Kuznetsova, A. N. Kulikov, N. V. Lareva, E. V. Makarova, S. V. Malchikova, S. V. Nedogoda, M. M. Petrova, I. G. Pochinka, K. V. Protasov, D. N. Protsenko, D. Yu. Ruzanov, S. A. Saiganov, A. Sh. Sarybaev, N. M. Selezneva, A. B. Sugraliev, I. V. Fomin, O. V. Khlynova, O. Yu. Chizhova, I. I. Shaposhnik, D. A. Schukarev, A. K. Abdrakhmanova, S. A. Avetisyan, H. G. Avoyan, K. K. Azaryan, G. T. Aimakhanova, D. A. Ayypova, A. Ch. Akunov, M. K. Alieva, A. R. Almukhambedova, O. Yu. Aparkina, O. R. Aruslanova, E. Yu. Ashina, O. Yu. Badina, O. Yu. Barysheva, T. I. Batluk, A. S. Batchaeva, R. A. Bashkinov, A. M. Bitieva, I. U. Bikhteev, N. A. Borodulina, M. V. Bragin, V. A. Brazhnik, A. M. Budu, G. A. Bykova, K. R. Vagapova, D. D. Varlamova, N. N. Vezikova, E. A. Verbitskaya, O. E. Vilkova, E. .A. Vinnikova, V. V. Vustina, E. A. Elena A. Galova, V. V. Genkel, D. B. Giller, E. D. Gordeychuk, E. I. Gorshenina, E. V. Grigoryeva, E. Yu. Gubareva, G. M. Dabylova, A. I. Demchenko, O. Yu. Dolgikh, M. Y. Duishobaev, D. S. Evdokimov, K. E. Egorova48, A. E. Zheldybaeva, N. V. Zarechnova, Yu. D. Zimina, S. Yu. Ivanova, E. Yu. Ivanchenko, M. V. Ilina, M. V. Kazakovtseva, E. V. Kazymova, Yu. S. Yuliya S. Kalinina, N. A. Kamardina, A. M. Karachenova, I. A. Karetnikov, N. A. Karoli, M. Kh. Karsiev, D. S. Kaskaeva, K. F. Kasymova, Zh. B. Kerimbekova, E. S. Kim, N. V. Kiseleva, D. A. Klimenko, O. V. Kovalishena, S. V. Kozlov, E. V. Kolmakova, T. P. Kolchinskaya, M. I. Kolyadich, O. V. Kondryakova, M. P. Konoval, D. Yu. Konstantinov, E. A. Konstantinova, V. A. Kordyukova, E. V. Koroleva, A. Yu. Kraposhina, T. V. Kryukova, A. S. Kuznetsova, T. Yu. Kuzmina, K. V. Kuzmichev, C. K. Kulchoroeva, T. V. Kuprina, I. M. Kuranova, L. V. Kurenkova, N. Yu. Kurchugina, N. A. Kushubakova, V. I. Levankova, A. A. Ledyaeva, T. V. Lisun, V. E. Lisyanskaya, N. A. Lyubavina, N. A. Magdeeva, K. V. Mazalov, V. I. Mayseenko, A. S. Makarova, A. M. Maripov, N. V. Markov, A. A. Marusina, E. S. Melnikov, A. I. Metlinskaya, N. B. Moiseenko, F. N. Muradova, R. G. Muradyan, Sh. N. Musaelyan, E. S. Nekaeva, N. M. Nikitina, S. E. Nifontov, E. Yu. Obolentseva, A. A. Obukhova, B. B. Ogurlieva, A. A. Odegova, Yu. V. Yuliya V. Omarova, N. A. Omurzakova, Sh. O. Ospanova, V. A/ Pavlova, E. V. Pakhomova, L. D. Petrov, S. S. Plastinina, D. A. Platonov, V. A. Pogrebetskaya, D. V. Polyakov, E. V. Ponomarenko, L. L. Popova, A. A. Potanin, N. A. Prokofieva, Yu. D. Rabik, N. A. Rakov, A. N. Rakhimov, N. A. Rozanova, S. Serikbolkyzy, Ya. A. Sidorkina, A. A. Simonov, V. V. Skachkova, R. D. Skvortsova, D. S. Skuridin, D. V. Solovieva, I. A. Solovieva, I. M. Sukhomlinova, A. G. Sushilova, D. R. Tagaeva, E. P. Tikhonova, D. S. Tokmin, A. A. Tolmacheva, M. S. Torgunakova, K. V. Trenogina, N. A. Trostyanetskaya, D. A. Trofimov, M. A. Trubnikova, A. A. Tulichev, A. T. Tursunova, N. D. Ulanova, O. V. Fatenkov, O. V. Fedorishina, T. S. Fil, I. Yu. Fomina, I. S. Fominova, I. A. Frolova, S. M. Tsvinger, V. V. Tsoma, M. B. Cholponbaeva, T. I. Chudinovskikh, I. V. Shavrin, O. A. Shevchenko, D. R. Shikhaliev, E. A. Shishkina, K. Yu. Shishkov, S. Yu Shcherbakov, G. V. Shcherbakova, E. A. Yausheva

“…Demographic, clinical, and laboratory data, computed tomography (CT) results, information about inhospital clinical course and complications of COVID-19 during hospitalization were extracted from electronic health records using a standardized data collection form. …”
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Socioeconomic status and lifestyle as factors of multimorbidity among older adults in China: results from the China Health and Retirement Longitudinal Survey by Wei Gong, Wei Gong, Wei Gong, Xiaoxiao Hu, Huimin Cui, Huimin Cui, Yuxin Zhao, Yuxin Zhao, Hong Lin, Hong Lin, Hong Lin, Peng Sun, Peng Sun, Jianjun Yang, Jianjun Yang

“…Socioeconomic and functional variables were dominant factors associated with multimorbidity, suggesting structural roots of health inequality. These findings offered empirical and theoretical support for early risk stratification and targeted public health interventions aimed at mitigating multimorbidity in aging populations.…”
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Landslide susceptibility assessment in Western Henan Province based on a comparison of conventional and ensemble machine learning by Wen-geng Cao, Yu Fu, Qiu-yao Dong, Hai-gang Wang, Yu Ren, Ze-yan Li, Yue-ying Du

“…These areas have large terrain fluctuations, complicated geological structural environments and frequent human engineering activities. …”
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Whole-Genome Resequencing Analysis of Copy Number Variations Associated with Athletic Performance in Grassland-Thoroughbred by Wenqi Ding, Wendian Gong, Tugeqin Bou, Lin Shi, Yanan Lin, Xiaoyuan Shi, Zheng Li, Huize Wu, Manglai Dugarjaviin, Dongyi Bai

“…These findings provide new insights into the genetic structural variation in racing performance and adaptability, fill the gap in CNV studies in the genomics of Grassland-Thoroughbred horses, and offer valuable genomic data for optimizing breeding strategies in native racing horse populations.…”
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Development and Application of a Senolytic Predictor for Discovery of Novel Senolytic Compounds and Herbs by Jinjun Li, Kai Zhao, Guotai Yang, Haohao Lv, Renxin Zhang, Shuhan Li, Zhiyuan Chen, Min Xu, Naixue Yang, Shaoxing Dai

“…In the DrugBank database, 98 structurally novel candidate compounds with potential senolytic activity were identified. …”
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Artificial Intelligence in Breast Cancer Diagnosis and Treatment: Advances in Imaging, Pathology, and Personalized Care by Petar Uchikov, Usman Khalid, Granit Harris Dedaj-Salad, Dibya Ghale, Harney Rajadurai, Maria Kraeva, Krasimir Kraev, Bozhidar Hristov, Mladen Doykov, Vanya Mitova, Maria Bozhkova, Stoyan Markov, Pavel Stanchev

“…However, challenges include data variability, ethical concerns, and real-world validation. …”
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