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52441
Distinct subnetworks of the mouse anterior thalamic nuclei
Published 2025-07-01“…The anterior thalamic nuclei (ATN), a Papez circuit component, encompass the anterodorsal (AD), anteroventral (AV), and anteromedial (AM) thalamic nuclei. Structurally, the ATN facilitate communication among the neocortex, hippocampus, amygdala, and hypothalamus. …”
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52442
Climate Change Risk, Performance, and Value Added in Agricultural Sector
Published 2024-09-01“…The study period spans from 2010 to 2020, and the quantile regression method is employed on panel data to conduct the analysis. Methodology The general definition of quantile regression states that if the linear regression model is assumed as the following equation, we have: yi=ˊxiβτ+uτi. 0<τ<1 (1) Quantτ(yi|xi)=xiβτ (2) Equation (2) shows the τth conditional quantile function of the y distribution under the condition of random variables x in which the following condition holds: Quantτ(uτi|xi)=0 (3) In the quantile regression structure, the effect of observable features on the conditional distribution is estimated through the process of minimizing the absolute value of the error element. …”
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52443
A worldwide study of subcortical shape as a marker for clinical staging in Parkinson’s disease
Published 2024-11-01“…We investigated disease effects using mass univariate and multivariate models on the medial thickness of 27,120 vertices of seven bilateral subcortical structures. Shape differences were observed across all Hoehn and Yahr (HY) stages, as well as correlations with motor and cognitive symptoms. …”
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52444
The effects of computerised decision support systems on nursing and allied health professional performance and patient outcomes: a systematic review and user contextualisation
Published 2024-10-01“…Risk of bias Assessed using structured risk of bias guidelines; almost all included studies were at high risk of bias. …”
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52445
Desenvolvimento de carreiras e perceção de fatores para a excelência do árbitro de futebol em Portugal (Desarrollo profesional y percepción de factores a la excelencia del árbitro...
Published 2020-01-01“…This study aimed to identify the career and the path/development of the Portuguese soccer referees who reached the level of excellence and assess their perceptions about the determinant/decisive factors to reach that level. Five semi-structured interviews were conducted with referees and former soccer referees who reached the international category, in football or futsal, using a transverse retrospective design. …”
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52446
Consequências do comportamento sedentário no bem-estar psicossocial: estudo qualitativo com idosos residentes em Portugal (Consequences of sedentary behavior on psychosocial well-...
Published 2021-10-01“…Questionnaires were used to determine the average daily time spent in different sedentary behaviors and the usual level of physical activity. Data were also collected through semi-structured interviews and analyzed using thematic analysis techniques. …”
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52447
Recurrent Jetlets Associated with the Disappearance of a Satellite Spot
Published 2025-01-01“…The horizontal magnetic field of the satellite spot consistently exhibited a vortex structure throughout its evolution until it vanished. …”
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52448
Molecular characteristic, evolution, and pathogenicity analysis of avian infectious bronchitis virus isolates associated with QX type in China
Published 2024-12-01“…Analysis of the S1 subunit structure revealed that mutations of amino acid residues in the hypervariable region (HVR) and the neutralizing epitope region resulted in antigenic variation in isolates by changing the antigen conformation. …”
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52449
Exploring the impact of APOE ɛ4 on functional connectivity in Alzheimer’s disease across cognitive impairment levels
Published 2025-01-01“…Studies have shown that APOE ɛ4 mediates the modulation of intrinsic functional brain networks in cognitively normal individuals and significantly disrupts the whole-brain topological structure in AD patients. However, how APOE ɛ4 regulates brain functional connectivity (FC) and consequently affects the levels of cognitive impairment in AD patients remains unknown. …”
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52450
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52451
Identifying the Components of Iranian Adolescent Compassionate Mind Training Program
Published 2024-05-01“…Participants included university professors and school counsellors with extensive experience in relevant fields. Data was collected through semi-structured interviews, focusing on the essential components of compassion training for adolescents, distinguishing features of Iranian adolescents, and additional elements needed for cultural adaptation. …”
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52452
Comparing the Effectiveness of Self-Compassion and Mindfulness Therapies on Affection Control of Poor Parenting Adolescents
Published 2024-11-01“…Mindfulness, is another significant structure of peoples’ reaction modulating toward uncomfortable situations. …”
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52453
Right atrial strain in Anderson–Fabry disease
Published 2025-02-01“…BackgroundTo date, only limited data are available on right atrium (RA) morphofunctional remodeling in Fabry disease (FD).PurposeWe aimed to investigate RA structural and functional remodeling in patients with FD vs. healthy controls using 2D speckle tracking echocardiography (STE) and to explore whether any differences exist in FD patients with and without left ventricular hypertrophy (LVH).MethodsWe prospectively enrolled patients with FD and controls matched for age, sex, and cardiovascular risk factors. …”
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52454
Multi-omics insights into functional alterations of the liver in growth-retarded offspring: transcriptomic, epigenetic and metabolomic profiles
Published 2025-08-01“…Compared to high weaning weight (HWW) piglets, the liver of low weaning weight (LWW) piglets was predominantly characterized by hepatic vacuolation and structural lesions. Transcriptomic analysis of the liver indicated that differentially expressed genes (DEGs) linked to amino acid metabolism (IDO1, DAO, and UROC1) and innate immune (ISG15, RSAD2, and IFIT1) showed significant upregulation in the high birth weight (HBW) piglets when compared to the low birth weight (LBW) piglets. …”
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52455
Evaluation of the innate immunostimulatory potential of originator and non-originator copies of insulin glargine in an in vitro human immune model.
Published 2018-01-01“…<h4>Background</h4>The manufacture of insulin analogs requires sophisticated production procedures which can lead to differences in the structure, purity, and/or other physiochemical properties of resultant products that can affect their biologic activity. …”
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52456
Validation of Quantitative Ultrasound and Texture Derivative Analyses-Based Model for Upfront Prediction of Neoadjuvant Chemotherapy Response in Breast Cancer
Published 2025-04-01“…Explanations for the misclassified cases included unplanned modifications made to the type of chemotherapy during treatment, inherent limitations of the predictive model, presence of DCIS in tumour structure, and an ill-defined tumour border in a minority of cases. …”
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52457
Genome-Wide Identification of <i>G3BP</i> Family in U’s Triangle <i>Brassica</i> Species and Analysis of Its Expression in <i>B. napus</i>
Published 2025-07-01“…We then analyzed their gene structure, protein motifs, gene duplication type, phylogeny, subcellular localization, SSR loci, and upstream miRNAs. …”
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52458
Bacteroides uniformis-generated hexadecanedioic acid ameliorates metabolic-associated fatty liver disease
Published 2025-12-01“…Distinct differences were identified in both the microbial community structure and metabolomic profiles between MAFLD patients and healthy controls. …”
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52459
Cluster Candidates with Massive Quiescent Galaxies at z ∼ 2
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52460
Genetic Interplay Between Attention-Deficit/Hyperactivity Disorder and Pain Suggests Neurodevelopmental Pathways and Comorbidity Risk
Published 2025-07-01“…In the independent sample, higher MCP PRSs were linked to structural brain features, increased comorbidity with substance use and bipolar disorder, and heightened severity of ADHD symptoms. …”
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