Hydrothermal synthesis of a nickel-oxide-infused orange peel nanobiocomposite for enhanced heavy metal removal from mining wastewater by Jacques Romain Njimou, Velma Fai, Mary Tamwa Sieugaing, Djimongbaye Nguenamadje, John Godwin, Oben Bessem Genola, Guy Bertrand Noumi, Bankim Chandra Tripathy

“…Characterization techniques such as FTIR, XRD, SEM, and EDS reveal a highly porous morphology due to NiO nanoparticle integration within the OP matrix, a structure that provides numerous active sites for adsorption. …”
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Synthesis of the serotonin derivative 5-PT and establishment of a research system for protein serotonylation by XIAO Shuyu, TULAMATI Aziguli, YANG Yan, ZHANG Zhigang, YANG Xiaomei, DU Chang, ZHANG Xueli

“…Mass spectrometry analysis data showed that a significant amount of serotonylated proteins were enriched in various cells treated with 5-PT. …”
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Risk Factors, Clinical Characteristics, and Antibiotic Susceptibility Patterns of <i>Streptococcal</i> Keratitis: An 18-Year Retrospective Study from a Tertiary Hospital in China by Zhen Cheng, Qingquan Shi, Bo Peng, Zijun Zhang, Zhenyu Wei, Zhiqun Wang, Yang Zhang, Kexin Chen, Xizhan Xu, Xinxin Lu, Qingfeng Liang

“…IVCM revealed deeper inflammatory cell distribution and structural disruption as the disease progressed. Resistance rates of aminoglycosides, β-lactams, and fluoroquinolones have increased, with significant differences among species for amikacin (<i>p</i> = 0.010), gentamicin (<i>p</i> = 0.007), and others. …”
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Clinical genome sequencing in patients with hereditary breast and ovarian cancer: Concept, implementation and benefits by Dennis Witt, Marc Sturm, Antje Stäbler, Benita Menden, Lisa Ruisinger, Kristin Bosse, Ines Gruber, Andreas Hartkopf, Silja Gauß, German Demidov, Nicolas Casadei, Elena Buena Atienza, Kira Mehnert, Janna Witt, Caspar Gross, Leon Schütz, Christopher Schroeder, Stephan Ossowski, Andreas Dufke, Tobias B. Haack, Olaf Riess, Ulrike Faust

“…GS offers a wealth of information, including the improved detection of structural variants, copy number variants, and parallel detection of complex genetic markers. …”
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The antioxidant property of CAPE depends on TRPV1 channel activation in microvascular endothelial cells by Miltha Hidalgo, Bárbara Railef, Vania Rodríguez, Carolina Navarro, Vanessa Rubio, Jorge Meneses-Pacheco, Sandra Soto-Alarcón, Christine Kreindl, Carolina Añazco, Leandro Zuñiga, Omar Porras

“…Herein, we hypothesized that a subfamily of TRP ion channels works as the molecular entity that recognizes CAPE at the plasma membrane and allows a fast shift in the antioxidant capacity of intact endothelial cells (EC).By monitoring cytoplasmic Ca2+ in a microvascular EC model, we compared the calcium responses evoked by three structurally related compounds: caffeic acid phenethyl ester, neochlorogenic acid and caffeic acid. …”
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Optical genome mapping: Unraveling complex variations and enabling precise diagnosis in dystrophinopathy by Jiahui Mai, Jing Duan, Xiaoyu Chen, Liqin Liu, Dachao Liang, Tao Fu, Gang Lu, Wai Yee Chan, Xufeng Luo, Feiqiu Wen, Jianxiang Liao, Zhuo Li, Xinguo Lu

“…We used the optical genome mapping (OGM) technology to detect and analyze uncommon mutations or structural variations (SVs) within the DMD gene, thus contributing to more precise clinical diagnoses. …”
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CTV-MIND: A cortical thickness-volume integrated individualized morphological network model to explore disease progression in temporal lobe epilepsy by Xinyan Liu, Jiaqi Han, Xiating Zhang, Boxuan Wei, Lu Xu, Qilin Zhou, Yuping Wang, Yicong Lin, Jicong Zhang

“…This study aimed to investigate progressive changes in TLE by constructing a novel individualized morphological brain network based on T1-weighted structural magnetic resonance imaging (MRI). MRI data were collected from 34 postoperative seizure-free TLE patients and 28 age- and sex-matched healthy controls (HC), with patients divided into LONG-TERM and SHORT-TERM groups. …”
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Safety of mycophenolate mofetil in systemic lupus erythematosus maintenance therapy: insights from the LUNA registry in a nationwide prospective cohort study by Ken-ei Sada, Shuhei Yoshida, Kenji Saito, Yuya Fujita, Eisuke Inoue, Kiyoshi Migita, Naoki Matsuoka, Hiroshi Kajiyama, Ryusuke Yoshimi, Kunihiro Ichinose, Yoshia Miyawaki, Shigeru Ohno, Nobuyuki Yajima, Yasuhiro Shimojima, Shuzo Sato, Michio Fujiwara, Keisuke Nishimura, Takashi Kida, Yuya Sumichika, Haruki Matsumoto, Jumpei Temmoku, Tomoyuki Asano, Shotaro Ogawa, Jumpei Fukita, Yusuke Matsuo, Takahisa Onishi

“…Statistical analyses employed marginal structural models with stabilised inverse probability of treatment weighting to adjust for confounders.Results The analysis included 1004 patients; the incidence of severe infections was 6.5% in the MMF group and 7.5% in the non-MMF group, with no significant difference (OR 0.69, 95% CI 0.34 to 1.39). …”
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The mediating role of physical activity avoidance in the association between weight stigma and physical activity by Po-Ching Huang, Hung-Ching Wu, Ji-Kang Chen, Xavier C.C. Fung, Nadia Bevan, Daniel Kwasi Ahorsu, Mark D. Griffiths, Jung-Sheng Chen, Kuo-Hsin Lee, Amir H. Pakpour, Chung-Ying Lin

“…Results: Structural equation modeling showed that weight-related self-stigma was significantly associated with PA avoidance (standardized coefficient [β] = 0.67, p < 0.01), and negatively associated with PA (β = −0.14, p < 0.01). …”
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Executive dysfunction relates to salience network desegregation in behavioural variant frontotemporal dementia by Melanie A. Matyi, Hamsanandini Radhakrishnan, Christopher A. Olm, Jeffrey S. Phillips, Philip A. Cook, Emma Rhodes, James C. Gee, David J. Irwin, Corey T. McMillan, Lauren Massimo

“…Given that behavioral variant frontotemporal degeneration (bvFTD) is a neurodegenerative disease associated with executive dysfunction and selective vulnerability of the salience network, we tested the hypotheses that bvFTD structural networks are de-differentiated compared to cognitively normal controls (CNC) and that network de-differentiation relates to worse executive function. …”
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Single-cell chromatin accessibility profiling reveals regulatory mechanisms and evolution in pig brains by Yue Xiang, Saixian Zhang, Yi Huang, Zhuqing Zheng, Jiahui Sun, Qiulin Zhao, Peng Zhou, Xiaolong Qi, Jingjin Li, Fuyang Xiong, Jing Xu, Shengquan Wang, Liangliang Fu, Xinyun Li

“…Abstract Background Pig brains serve as a valuable biomedical model for studying brain-related diseases due to their significant structural similarities to the human brain. Furthermore, the long-term domestication and artificial selection of domestic pigs have profoundly shaped their brains, making them an interesting subject for research. …”
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Advancing molecular diagnostics of myotonic dystrophy type 1 using short-read whole genome sequencing by Ingrid Lojova, Marcel Kucharik, Zuzana Pös, Andrej Balaz, Andrea Zatkova, Eva Tothova Tarova, Jaroslav Budis, Ludevit Kadasi, Tomas Szemes, Jan Radvanszky

“…WGS was found to be superior in elucidating the sequence structure of the motifs, even if they fall outside the sizing limit (from partial reads). …”
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The burden of a new coronavirus infection in a Children’s multidisciplinary hospital in St. Petersburg 2020–2021 by E. A. Dondurei, V. А. Kondratev, L. N. Isankina, N. Yu. Kaika, Yu. A. Gaist, V. V. Yesikov, I. M. Kosenko, V. A. Kaziakhmedov, K. V. Pshenisnov, O. V. Zabirova, S. I. Dvorak, L. V. Ivanova, O. O. Osipova, O. I. Afanasyeva, D. A. Lioznov

“…The analysis of the underlying condition’s structure depending on the severity of the disease, as well as the need and volume of therapy in the intensive care unit. …”
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Results of modern radiation-hygienic surveys of settlements of Bryansk Oblast of the Russian Federation bordering the Republic of Belarus. Part 1: Characteristics of the settlement... by I. K. Romanovich, A. B. Bazyukin, A. N. Barkovsk, A. M. Biblin, A. A. Bratilova, G. Ya. Bruk, K. V. Varfolomeev, A. V. Gromov, E. A. Drozdova, T. V. Zhesko, S. A. Ivanov, M. V. Kaduka, T. A. Kormanovskaya, O. S. Kravtsova, V. A. Nekrasov, V. P. Ramzaev, K. A. Saprykin, N. V. Titov, O. A. Isakov, E. I. Zlotnikova, A. G. Sosnitskiy, V. I. Filin, A. V. Kudryashov, A. A. Ladik, V. A. Lalayan

“…The modern demographic composition of the population is considered; the structure of private subsidiary plots is investigated. …”
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Research on the charging periods of the ultra-shallow play in front of the Hashan area, northwestern margin of the Junggar Basin by WANG Qianjun, ZHOU Jian, ZHANG Faqiang, YU Hongzhou, WU Qianqian, LU Hongli, LIU Qingxin, ZHOU Yu, CHENG Ming, YAN Jianzhao, LYU Yanfang

“…The second phase took place during the Late Cretaceous (73 Ma), marked by structural adjustment and hydrocarbon redistribution. …”
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Livestock rearing as a key component of mitigation efforts for non-CO2 greenhouse gas emissions in global crop-livestock system by Li Zheng, Qingwen Zhang, Ji Chen, Baojing Gu, Xiaoying Zhan, Bowei Yu, Yulong Shi, Hafiz Athar Hussain, Xuekai Jing

“…The Logarithmic Mean Divisia Index (LMDI) was used to decompose drivers and six scenarios (BAU (Baseline), RSA (Rearing Structure Adjustment), LMO (Livestock Management Optimization), BMPs-30% and BMPs-50% (best management practices with a manure substitution ratio of 30% or 50%), and NMA (No Manure Application)) were developed to assess mitigation potential. …”
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Comparison of right ventricular function and clinical outcomes in type 2 diabetes patients with and without obstructive coronary artery disease: insights from a CMR study by Jin Wang, Wei-Feng Yan, Ke Shi, Hua-Yan Xu, Shi-Qin Yu, Ying-Kun Guo, Li Jiang, Yue Gao, Yu-Jiang, Xue-Ming Li, Yuan Li, Zhi-Gang Yang

“…Cardiovascular magnetic resonance were utilized to assess RV structure, function, and global myocardial strain [including peak strain (PS), peak systolic (PSSR) and diastolic strain rate (PDSR) in longitudinal, circumferential, and radial directions]. …”
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The potential spatiotemporal distribution patterns of Avena nuda and Avena sativa from global perspective provide new insights for the cultivation of commonly cultivated oats by Huanhuan Lu, Yuying Zheng, Ting Zhao, Liuban Tang, Fan Zhang, Wengang Xie

“…Abstract Background Commonly cultivated oats (Avena nuda and Avena sativa) play an important role in agricultural planting structure adjustment, ecological environment protection and grassland animal husbandry development, and their effective cultivation is conducive to food security and grassland degradation restoration. …”
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Extracellular Vesicles Present in Bone Marrow Mesenchymal Stromal/Stem Cell Conditioned Media Restore Spermatogenesis in Azoospermic Mice by Rano Zhankina, Afshin Zare, Alireza Afshar, Arezoo Khoradmehr, Mohammad Reza Dorvash, Farhad Rahmanifar, Nader Tanideh, Omid Koohi Hosseinabadi, Ali Arabi Monfared, Shahrokh Zare, Nadiar Mussin, Asset Askerovich Kaliyev, Ulanbek Zhanbyrbekuly, Amin Tamadon

“…Additionally, protein structure extraction, protein-protein docking analysis, and data visualization were conducted.Results: Histomorphometry and flow cytometry showed that most seminiferous tubules in the therapy groups exhibit­ed normal morphology and restored spermatogenesis, unlike the azoospermia group. …”
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Assessing the quality of care in primary health care facilities in all municipalities in Kosovo 2016–2023 by Astrid M. Knoblauch, Astrid M. Knoblauch, Sarah Rajkumar, Sarah Rajkumar, Robert Canavan, Robert Canavan, Qamile Ramadani, Ariana Bytyçi Katanolli, Shegë Bahtiri, Debra Stevenson, Debra Stevenson, Debra Stevenson, Merita Stavileci Mustafa, Nicu Fota, Nicu Fota, Nicu Fota, Jana Gerold, Jana Gerold

“…However, substantial challenges remain, particularly among managing non-communicable diseases (NCD) like diabetes and hypertension, due to gaps in structural and procedural aspects. The Accessible Quality Healthcare project (2016–2027) aimed at improving the health of the Kosovar population by strengthening the quality of PHC services with a specific focus on NCDs. …”
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