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57961
Roles of ACSL4/GPX4 and FSP1 in oxalate-induced acute kidney injury
Published 2025-06-01“…Furthermore, renal tubule-specific deficiency of Acsl4 conferred significant protection against oxalate-induced AKI, as evidenced by alleviated structural and functional renal damage, reduced oxidative stress and decreased inflammatory cell infiltration, all of which collectively contribute to a reduction in ferroptosis. …”
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57962
Unraveling regulation of the small heat shock proteins by the heat shock factor HvHsfB2c in barley: its implications in drought stress response and seed development.
Published 2014-01-01“…Recombinant HvsHsp17.5-CI protein was expressed in E. coli and purified to homogeneity, which displayed in vitro chaperone activity. The predicted structural model of HvsHsp-17.5-CI protein suggests that the α-crystallin domain is evolutionarily highly conserved.…”
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57963
C1 esterase inhibitor reduces lower extremity ischemia/reperfusion injury and associated lung damage.
Published 2013-01-01“…Deprivation of blood supply leads to molecular and structural changes in the affected tissue. Upon reperfusion inflammatory cascades are activated causing tissue injury. …”
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57964
Effects of milk fat globule membrane ingestion with exercise on physical strength in healthy young adults: a randomized double-blind, placebo-controlled trial
Published 2025-12-01“…Background The milk fat globule membrane (MFGM) is a structural membrane that covers the globules of triglycerides dispersed in an emulsion of milk. …”
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57965
Validity of the Chinese Mandarin version of the compassionate engagement and action scales for self and others for nursing students
Published 2025-07-01“…A non-probability sampling technique, specifically convenience sampling, was employed to recruit 428 nursing students to assess the validity and reliability of the measurement instrument from February to June 2024. Convergent, structural, and content validity were evaluated. Test-retest reliability and Cronbach’s alpha coefficient were used to assess reliability. …”
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57966
Global Trends and Empirical Metrics in the Evaluation of Code Smells and Technical Debt: A Bibliometric Study
Published 2025-01-01“…Among the critical factors that affect these attributes are code smells, indicators of structural deficiencies in the source code, which, although they do not directly affect functionality, significantly increase technical debt and maintenance costs. …”
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57967
Study on the mechanism of family resilience on loneliness in older adults with stroke
Published 2025-05-01“…Using one-way analysis of variance and multiple linear regression equation to analyze the influencing factors of loneliness in older adults with stroke; Construct a structural equation model to explore the pathways of social support, family function and psychological capital in the relationship between family resilience and loneliness.ResultsThe average loneliness score among older adults with stroke was (35.07 ± 15.24). …”
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57968
Dynamic land use efficiency and human-land relationship in traditional industrial cities
Published 2025-05-01“…Studying the dynamic land utilization efficiency during urbanization is crucial for understanding the human-land relationship in cities facing economic decline.MethodsUsing land utilization and population data from 2000 to 2020, a dynamic land utilization efficiency index was developed to identify patterns in land utilization dynamics at the district and county level and assess the coordination of human-land relationships at the municipal level. The spatial structural relationships among districts and counties are analysed using the Getis-Ord Gi* statistical model, while the co ordination mechanisms of human-land interactions are explored through the Kaya identity and the Logarithmic Mean Divisia Index (LMDI).ResultsThe results demonstrate that 40.9% of counties suffer from low land utilization efficiency. 57.6% of cities experience simultaneous population decline and expansion of urban-rural construction land. …”
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57969
A noncoding point mutation of Zeb1 causes multiple developmental malformations and obesity in Twirler mice.
Published 2011-09-01“…We conclude that a noncoding point mutation of Zeb1 acts via a gain-of-function to disrupt regulation of Zeb1(Tw) expression, epithelial-mesenchymal cell fate or interactions, and structural development of the inner ear in Twirler mice. …”
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57970
The mediating role of perceived overqualification in the relationship between emotional labor and mindfulness among nurses in China
Published 2025-03-01“…The SPSS version 27.0 statistical analysis software was employed for the basic organization and analysis of the survey data. A structural equation model was used to assess the mediating role of perceived overqualification between mindfulness and the emotional labor of clinical nurses.ResultsThe study indicated that the level of mindfulness and emotional labor among clinical nurses was moderate to high, whereas perceived overqualification was moderate. …”
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57971
Increased Brain Age Among Psychiatrically Healthy Adults Exposed to Childhood Trauma
Published 2025-04-01“…“Brain age” predictions were generated from T1‐weighted structural MRI scans using a pre‐trained machine learning pipeline, namely brainageR. …”
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57972
Principles for increasing equity in WASH research: understanding barriers faced by LMIC WASH researchers
Published 2023-04-01“…The social-ecological model was combined with this framework to identify the types of actors and the level of co-ordination needed to address these issues. …”
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57973
Factors influencing uptake of COVID-19 diagnostics in Sub-Saharan Africa: a rapid scoping review.
Published 2025-01-01“…<h4>Results</h4>In total 2994 articles were identified and fourteen reviewed. Structural, social, epidemiological, informational, and political elements affected how the public interacted with COVID-19 testing. …”
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57974
The Dynamics of Long Terminal Repeat Retrotransposon Proliferation and Decay Drive the Evolution of Genome Size Variation in Capsicum
Published 2025-07-01“…Notably, the integrity and transcriptional activity of LTR-RTs decline over evolutionary time; older insertions exhibit greater structural degradation and reduced activity, reflecting their dynamic nature. …”
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57975
Sustained Delivery of Liraglutide Using Multivesicular Liposome Based on Mixed Phospholipids
Published 2025-02-01“…<b>Results:</b> As the SPC ratio increased, Lir-MVLs had more flexible lipid membranes, poorer structural stabilization, and fewer internal vesicles with larger particle sizes, contributing to faster release of Lir. …”
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57976
“Old” and “New” Trust in Higher Education
Published 2019-02-01“…The need to preserve trust as a fundamental basis and source of development of Russian higher education requires the study of its structural characteristics and understanding of the resource potential of trust by representatives of educational communities.The aim of the research was the sociological substantiation of actualisation in higher education of the old resource properties of trust and the emergence of new ones associated with the prospects of transition to a non-linear model of higher education.Methodology and research methods. …”
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57977
Relationship between teachers’ cognitive activation practices, teacher characteristics and student achievement in science subdomains: a study of TIMSS 2019 in Sweden
Published 2025-06-01“…Methods Using the Swedish TIMSS 2019 data, multilevel structural equation modelling analyses were employed. …”
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57978
Lowering Blood Lipids and Regulating Intestinal Flora Effects of Blueberry Enzyme in Hyperlipidemic Mice
Published 2025-05-01“…The abundance and diversity of intestinal microbes were regulated, while structural composition of intestinal microbiota in hyperlipidemia mice was changed.…”
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57979
How does strategic orientation influence the business performance of small and medium-sized enterprises during the COVID-19 pandemic?
Published 2025-03-01“…Research Design & Methods: We surveyed 265 small and medium-sized enterprises and employed structural equation modelling (SEM) to test the hypotheses developed. …”
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57980
From ‘publish or perish’ to ‘publish with purpose’: perspectives from young adults with lived and living experience on transforming academic publishing in patient-oriented research...
Published 2024-12-01“…Set against a backdrop of systemic biases and structural barriers, this discussion underscores the persistent minoritization of YALLE, despite increasing nominal recognition within academic and health research communities. …”
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