Multimodal gradients unify local and global cortical organization by Yezhou Wang, Nicole Eichert, Casey Paquola, Raul Rodriguez-Cruces, Jordan DeKraker, Jessica Royer, Donna Gift Cabalo, Hans Auer, Alexander Ngo, Ilana R. Leppert, Christine L. Tardif, David A. Rudko, Robert Leech, Katrin Amunts, Sofie L. Valk, Jonathan Smallwood, Alan C. Evans, Boris C. Bernhardt

“…Here, we present an approach to integrate inter- and intra-areal similarities of microstructure, structural connectivity, and functional interactions. …”
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The XRISM/Resolve View of the Fe K Region of Cyg X-3 by XRISM Collaboration, Marc Audard, Hisamitsu Awaki, Ralf Ballhausen, Aya Bamba, Ehud Behar, Rozenn Boissay-Malaquin, Laura Brenneman, Gregory V. Brown, Lia Corrales, Elisa Costantini, Renata Cumbee, María Díaz Trigo, Chris Done, Tadayasu Dotani, Ken Ebisawa, Megan E. Eckart, Dominique Eckert, Satoshi Eguchi, Teruaki Enoto, Yuichiro Ezoe, Adam Foster, Ryuichi Fujimoto, Yutaka Fujita, Yasushi Fukazawa, Kotaro Fukushima, Akihiro Furuzawa, Luigi Gallo, Javier A. García, Liyi Gu, Matteo Guainazzi, Kouichi Hagino, Kenji Hamaguchi, Isamu Hatsukade, Katsuhiro Hayashi, Takayuki Hayashi, Natalie Hell, Edmund Hodges-Kluck, Ann Hornschemeier, Yuto Ichinohe, Manabu Ishida, Kumi Ishikawa, Yoshitaka Ishisaki, Jelle Kaastra, Timothy Kallman, Erin Kara, Satoru Katsuda, Yoshiaki Kanemaru, Richard Kelley, Caroline Kilbourne, Shunji Kitamoto, Shogo Kobayashi, Takayoshi Kohmura, Aya Kubota, Maurice Leutenegger, Michael Loewenstein, Yoshitomo Maeda, Maxim Markevitch, Hironori Matsumoto, Kyoko Matsushita, Dan McCammon, Brian McNamara, François Mernier, Eric D. Miller, Jon M. Miller, Ikuyuki Mitsuishi, Misaki Mizumoto, Tsunefumi Mizuno, Koji Mori, Koji Mukai, Hiroshi Murakami, Richard Mushotzky, Hiroshi Nakajima, Kazuhiro Nakazawa, Jan-Uwe Ness, Kumiko Nobukawa, Masayoshi Nobukawa, Hirofumi Noda, Hirokazu Odaka, Shoji Ogawa, Anna Ogorzalek, Takashi Okajima, Naomi Ota, Stephane Paltani, Robert Petre, Paul Plucinsky, Frederick S. Porter, Katja Pottschmidt, Kosuke Sato, Toshiki Sato, Makoto Sawada, Hiromi Seta, Megumi Shidatsu, Aurora Simionescu, Randall Smith, Hiromasa Suzuki, Andrew Szymkowiak, Hiromitsu Takahashi, Mai Takeo, Toru Tamagawa, Keisuke Tamura, Takaaki Tanaka, Atsushi Tanimoto, Makoto Tashiro, Yukikatsu Terada, Yuichi Terashima, Yohko Tsuboi, Masahiro Tsujimoto, Hiroshi Tsunemi, Takeshi Tsuru, Hiroyuki Uchida, Nagomi Uchida, Yuusuke Uchida, Hideki Uchiyama, Yoshihiro Ueda, Shinichiro Uno, Jacco Vink, Shin Watanabe, Brian J. Williams, Satoshi Yamada, Shinya Yamada, Hiroya Yamaguchi, Kazutaka Yamaoka, Noriko Yamasaki, Makoto Yamauchi, Shigeo Yamauchi, Tahir Yaqoob, Tomokage Yoneyama, Tessei Yoshida, Mihoko Yukita, Irina Zhuravleva, Ryota Tomaru, Tasuku Hayashi, Tomohiro Hakamata, Daiki Miura, Karri Koljonen, Mike McCollough

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Dissecting the properties of circulating IgG against streptococcal pathogens through a combined systems antigenomics-serology workflow by Alejandro Gomez Toledo, Sounak Chowdhury, Elisabeth Hjortswang, James T. Sorrentino, Nathan E. Lewis, Anna Bläckberg, Simon Ekström, Sven Kjellström, Arman Izadi, Berit Olofsson, Pontus Nordenfelt, Lars Malmström, Magnus Rasmussen, Johan Malmström

“…A selected subset of the identified antigens is then expressed recombinantly to isolate antigen-specific IgG, followed by characterization of the structural and functional properties of these antibodies. …”
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Simulation Analysis and Experimental Verification of the Transport Characteristics of a High-Volume CubeSat Storage Device by Yong Zhao, Yuhao Zhang, Zeming Zhao, Chenyuan Li, Lili Zhang, Xiaoze Yang, Honghao Yue, Caiting He, Jianlei Zhu, Ye erken Halishi, Youle Wu, Guicheng Xing, Milamujiang Kezierbieke

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Insights into Keratinocyte and Immunologic Landscape in Cutaneous Graft-Versus-Host Disease through Single-Cell Transcriptomics by Amy J. Petty, Adela Rambi Cardones, Yingai Jane Jin, Vaibhav Jain, Emily Hocke, Harsh B. Pathak, Amrita Mitra, Simon G. Gregory, M. Angelica Selim, Jennifer Y. Zhang

“…Very little is understood about the underlying pathogenesis underpinning injury at this location, especially the contribution of keratinocytes and other structural skin cells. We performed single-cell RNA sequencing to compare the transcriptome of epidermal and dermal chronic GVHD samples with that of healthy control samples. …”
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Food parenting stress among caregivers receiving government food assistance: a study from the United States by Faith Hardy, Alison Tovar, Emily G. Elenio, Yarisbel Melo Herrera, Michelle Perry, Katherine W. Bauer, Maya K. Vadiveloo

“…Nutrition education should be paired with supports that address structural barriers.…”
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ODEP-Based Robotic System for Micromanipulation and In-Flow Analysis of Primary Cells by Joanna Filippi, Paola Casti, Valentina Lacconi, Gianni Antonelli, Michele D’Orazio, Giorgia Curci, Carlo Ticconi, Rocco Rago, Massimiliano De Luca, Alessandro Pecora, Arianna Mencattini, Steven L. Neale, Luisa Campagnolo, Eugenio Martinelli

“…The induced responses obtained under time-variant ODEP stimulation reflect the cells’ chemical, morphological, and structural characteristics in an automated, flexible, and label-free manner. …”
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Evaluation of dengue virus seroprevalence in four boroughs of Mexico City among persons aged 5-35 years in 2022 by Eleazar Coba-Alcalá, Lilia Chihu-Amparán, Irma Yvonne Amaya-Larios, Susana Román-Pérez, Rene Santos-Luna, Lorena Suárez-Idueta, Sonia López-Álvarez, Cristal Morales-Trevizo, Jesús Felipe González-Roldán, Ruth Aralí Martínez-Vega, José Ramos-Castañeda

“…However, it is important to note that the structural conditions of the dwellings in these boroughs, which offer minimal barriers to vector infestation, could facilitate the establishment of local transmission under favorable conditions. …”
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Oral Small-Molecule GLP-1 Receptor Agonists: Mechanistic Insights and Emerging Therapeutic Strategies by Héctor Iván Saldívar-Cerón, Jorge Arturo Vargas-Camacho, Sonia León-Cabrera, Paola Briseño-Díaz, Ari Evelyn Castañeda-Ramírez, Axel Eduardo Muciño-Galicia, María Regina Díaz-Domínguez

“…Nevertheless, challenges persist regarding hepatic safety, pharmacodynamic variability, and limited long-term outcome data. This review integrates current structural, pharmacological, and clinical evidence, highlights key mechanistic innovations—including biased agonism, covalent binding strategies, and allosteric modulation—and discusses future directions for this rapidly evolving therapeutic class in metabolic disease management.…”
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Comprehensive Dissolution Study on Two Double Ce(IV) Phosphates with Evidence of Secondary CeO₂ Nanoparticle Formation by Anastasiia L. Listova, Anastasiia S. Kuzenkova, Mikhail A. Gerasimov, Elizaveta S. Kulikova, Roman D. Svetogorov, Daniil A. Novichkov, Alexei A. Averin, Vasiliy O. Yapaskurt, Anna Yu. Romanchuk, Stepan N. Kalmykov, Tatiana V. Plakhova

“…In contrast, the nanophase NaCe₂(PO₄)₃ exhibits exceptional structural and chemical stability, showing no signs of recrystallisation, phase transformation, or CeO₂ formation, even after extended ageing. …”
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USP7 V517F mutation as a mechanism of inhibitor resistance by Yu-Ling Miao, Fengying Fan, Yong-Jun Cheng, Li Jia, Shan-Shan Song, Xia-Juan Huan, Xu-Bin Bao, Jian Ding, Xuekui Yu, Jin-Xue He

“…We discovered a key treatment-emergent heterozygous mutation (V517F) in USP7 in the binding pocket of compounds as the primary cause of resistance to the USP7 inhibitor USP7-797. Our structural analysis, supported by AlphaFold2 predictions, indicates that the V517F mutation altered the conformation of the compound binding pocket, causing steric hindrance and reducing the affinity between USP7 and its inhibitors. …”
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Determinants of ICT Adoption and Performance in Healthcare: The Role of Individual Attributes and Organizational Contextual Factors by Abey Jose, Alejandro F. Mac Cawley, Luis Enberg Gaete, Guilherme Luz Tortorella, Roberto Vassolo, Manisha Kumar, Nick Rich, Maneesh Kumar

“…We conducted a global survey involving healthcare professionals (n =204) to understand the role of various determinants in adopting ICTs and their implications for organizational performance. Data was analyzed using Partial Least Squares Structural Equation Modelling (PLS-SEM) and multiple regression for micro-level constructs. …”
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The Expression and Molecular Roles of MAMDC2 in MSS Colorectal Cancer with a High Tumor Stromal Ratio by Yiling Liu, Shengnan Qian, Jia Wei, Jianting He, Minghui Li, Xiaobing Gao, Hong Cai, Yiqing Wang, Yue Han, Tianyuan Tan, Minhui Yang

“…The meprin/A5/PTPmu (MAM) domain, a conserved structural motif in transmembrane proteins, remains undercharacterized in CRC pathogenesis. …”
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Anthropogenic and natural influence on vegetation ecosystems from 1982 to 2023 by Teligeer Bao, Huaqiang Li, Yonghong Hao, Matthew Tom Harrison, Ke Liu, Gulnazar Ali

“…In addition, frequent land cover changes promoted the growth of greening trends (∼23%), which is linked to enhanced structural plasticity of vegetation. This effect has become more pronounced since 2000, with 92% of such changes occurring during this period. …”
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TET dioxygenases localize at splicing speckles and promote RNA splicing by Florian D. Hastert, Jasmin Weber, Christina Bauer, Andreas Zhadan, Deepanshu N. D. Singh, Thomas C. Dix, Roland Arnold, Sergey Bessonov, Matthias Soller, Heinrich Leonhardt, M. Cristina Cardoso, Maria Arroyo

“…This study explores the relationship between RNA splicing and the TET dioxygenase activity, shedding light on the role of hm5C (RNA 5-hydroxymethylcytosine), and TET proteins in RNA metabolism. Integrating data from mass spectrometry, AlphaFold structural modeling, microscopic analysis, and different functional assays, including in vitro splicing, TET proteins were found to regulate splicing. …”
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Exploring neural changes associated with suicidal ideation and attempts in major depressive disorder: A multimodal study by Juan Deng, Maomao Zhang, Guangxiang Chen, Xiaofei Lu, Xiaotong Cheng, Cheng Qin, Mingyuan Tian, Ke Gong, Kezhi Liu, Jing Chen, Wei Lei

“…Suicidal ideation (SI) and suicide attempts (SA) are highly prevalent in individuals with major depressive disorder (MDD). To explore the structural and functional neural changes associated with SI and SA, we analyzed multimodal Magnetic Resonance Imaging (MRI) data from 159 participants, including those with MDD with suicide attempts (SA group, n = 34), those with MDD with suicidal ideation but not attempts (SI group, n = 53), those with MDD without suicidal ideation (NSI group, n = 14), and healthy controls (HC, n = 59). …”
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Multi-sphere coupling characteristics and gas-bearing controlling factors of calcareous shale reservoirs in the Yadu-Ziyun-Luodian Aulacogen under Early Carboniferous platform-basi... by Kun Yuan, Kun Yuan, Kun Yuan, Bing Feng, Gangquan Li, Zongan Xue, Zongan Xue, Zongan Xue, Tuo Lin, Tuo Lin, Tuo Lin, Xinxin Fang, Xiangcan Sun, Xiangcan Sun, Xiangcan Sun, Yinbo Xu, Yinbo Xu, Yinbo Xu, Fengzan Zheng

“…Integrating field geological surveys and well data, this study comprehensively evaluates the mineralogy, geochemistry, structural features, and gas content of these shales to decipher the key factors controlling gas enrichment, particularly in this tectonically complex area. …”
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Study on the Interaction Mechanism Between Urbanization and Ecological Resilience—The Case of Urban Agglomeration on the North Slope of Tianshan Mountain by Yanjun Tong, Tiange Shi, Shubao Zhang, Yunjie Cheng, Jiangyan Liang, Jun Lei

“…Based on land use change data, an ecological resilience evaluation model is constructed using the InVSET model, the landscape pattern index, and the unit area value equivalent factor method. …”
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Deconstructing Digital Transformation: A Multidimensional Analysis of Digital Literacy’s Role in Shaping Human Capital and Driving Organizational Success by Meena G, Santhanalakshmi K.

“…The research employs structural equation modeling and demonstrates robust interrelationships between variables (correlations ranging r=0.689 to 0.817), with digital literacy and employee commitment exhibiting the strongest correlation (r=0.817). …”
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Optimized stress-strain modeling of eco-friendly fiber-reinforced concrete members using meta-heuristic algorithms by Sawsan Akram Hassan, Mahir M. Hason, Ammar N. Hanoon, Ali A. Abdulhameed

“…The study demonstrates that adding sustainable fibers to concrete improves its structural integrity while lessening its environmental impact. …”
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