Investigating the regulation of the miR-199a-3p/TGF-β/Smad signaling pathway by BSHXF drug-containing serum combined with ADSCs for delaying intervertebral disc degeneration by Enxu Liu, Enxu Liu, Yu Sun, Yu Sun, Lei Yang, Lei Yang, Haobo Jiang, Haobo Jiang, Fei Sun, Long Chen, Jiahao Duan, Jiahao Duan, Shaofeng Yang, Shaofeng Yang

“…BSHXF restored TGF-β/Smad pathway activity by downregulating miR-199a-3p expression, thereby improving disc structure and function. This integrated approach offers a novel multi-target intervention strategy for IDD, demonstrating significant therapeutic potential.…”
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THE TERM COMBINATION AND THE METAPHOR IN THE OFFICIAL BUSINESS DOCUMENT: COGNITIVE ASPECT by Yuliya I. Demyanchuk.

“…The removal of the highly specialized terminology from NATO’s official business documents is conditioned by the presence of language units with the semantic structure indicating military, political and humanitarian features that distinguish NATO from other organizations. …”
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SI TAMEN PLURES PER SE NAVEM EXERCEANT. KILKA UWAG O ODPOWIEDZIALNOŚCI ARMATORÓW by Zuzanna Służewska

“…First of all, one must take into consideration that the word exercitor was a technical term used to define someone conducting an economic activity through his agent (magister navis) so it was normally used in the context of the whole structure of exercitio navis that was based on the scheme exercitor — magister navis. …”
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Experimental Study on the Influence of Crack Penetration Rate on Strength Properties of Expansive Soil by HU Bo, WANG Shuai, SUN Hui, GENG Hong-bin, WANG Qing, ZHOU Hong-jun

“…Combined with the Mohr-Coulomb strength criterion and strength calculation methods for cracked surfaces, a composite strength analysis framework for the “soil block-crack” structure was established. Compared to traditional crack simulation methods, this technique enables precise control of crack geometry, effectively reproducing the crack development process and providing robust data support. …”
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Optimization of composition and technology for tablets containing aspen bark extract by O. I. Onуshkiv

“…The dry aspen bark extract is hygroscopic fine powder with particles of anizodiametric shape.Namely, from the group of samples of microcrystalline cellulose (MCC) – Prosolv 90 (Silicified MCC, manufactured by JRS Pharma GMBH & Co KG., Germany), from the group structure-based substances sugars – Ludiflash (combination of mannitolCrospovidone, Povidone and polyvinyl acetate, manufactured by BASF Corp., USA) and from the group of disintegrants – Polyplasdone XL 10 (homopolymer of vinyl pyrrolidone, manufactured by manufactured by Ashland Inc., USA). …”
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Exemples d’habitats aristocratiques sur les sites des rues Eugène-Desteuque et Ponsardin à Reims/Durocortorum by Magalie Cavé, Stéphane Sindonino, Sabine Groetembril

“…This open-air area remained a major structuring element despite changes made elsewhere to the habitat. …”
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Heterologous Expression and Enzymatic Properties of β-Glucuronidase from <i>Clostridium perfringens</i> and Its Application in Bilirubin Transformation by Qianlin Wu, Qing Guo, Fo Yang, Mengru Li, Yumeng Zhu, Binpeng Xu, Lu Zhao, Shanshan Zhang, Youyu Xie, Feng Li, Xiaomin Wu, Dayong Xu

“…The three-dimensional structure of CpGUS was predicted using AlphaFold2 (AlphaFold v2.0, DeepMind Technologise Limited, London, UK), and p-Nitrophenyl-β-D-Glucuronide (pNPG) and conjugated bilirubin were then docked to the CpGUS protein model using SWISSDOCK. …”
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Wuda Granule Alleviates DSS-Induced Colitis in Mice by Inhibiting Inflammation, Protecting Intestinal Barrier and Reducing Oxidative Stress Through Nrf2/Keap1/HO-1 Pathway by Wang T, Ou Y, Xiong W, Luo L, Xu Y, Chen G, Peng Y, Chen Y, Zeng H, Yu Y, Tang H, Yao H, Wang W

“…Histological analysis revealed preserved colon structure and reduced inflammatory infiltration. WDG suppressed the expression of pro-inflammatory mediators (IL-6, IL-1β, TNF-α, MPO) and enhanced the levels of anti-inflammatory cytokines (IL-10 and IL-22). …”
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Resveratrol supplementation improves productivity and health in heat-stressed lactating Holstein cows by M.R.R. Nair, K. Frady, Z. Yu, J.M. Cantet, M.S. Hasan, A.G. Ríus

“…Fixed effects included main effects of treatment, parity, day, time, and all possible interactions with day and time as repeated measures, and animal was included as a random effect. The autoregressive structure was used based on the lower Akaike and Bayesian information criteria. …”
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Evaluation of the Curative Effect of Umbilical Cord Mesenchymal Stem Cell Therapy for Knee Arthritis in Dogs Using Imaging Technology by Bei-ying Zhang, Bing-yun Wang, Shao-chuan Li, Dong-zhang Luo, Xiaoshu Zhan, Sheng-feng Chen, Zhi-sheng Chen, Can-ying Liu, Hui-qin Ji, Yin-shan Bai, Dong-sheng Li, Yang He

“…A suspension of allogeneic UC-MSCs (1 × 106) and an equal amount of physiological saline was injected into the cavitas articularis in the treated and untreated control groups, respectively, on days 1 and 3 posttreatment. The structure of the canine knee joint was observed by magnetic resonance imaging (MRI), B-mode ultrasonography, and X-ray imaging at the 3rd, 7th, 14th, and 28th days after treatment. …”
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Updates on Donor-Derived Infection in Solid Organ Transplantation, Report from the 2024 GTI (Infection and Transplantation Group) Annual Meeting by Carole Eldin, Paolo Antonio Grossi, Victoria Manda, Nassim Kamar, Olivier Lortholary, Hans H. Hirsch, Jean-Ralph Zahar, Vincent Michel Borderie, François Parquin, Eric Epailly, Florence Ader, Emmanuel Morelon, Edouard Forcade, David Lebeaux, Jérôme Dumortier, Filomena Conti, Agnes Lefort, Agnes Lefort, Anne Scemla, Hannah Kaminski

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Development and validation of scales measuring self-efficacy and behavioral capability in managing common medical emergencies in dental clinics by Yasmine N. Alawaji, Hussam M. Alqahtani, Abdulmohsen Alfadley, Aram Alshehri, Ali Aboalela, Sahr H. Altuwaijri, Farraj Albalawi, Sara A. Kalagi, Abdulrhman Alghamdi, Abdullah Alshibani, Meshal Alharbi, Meshary Binhotan, Nesrin A. Alharthy

“…Using confirmatory factor analysis, the internal structure of self-efficacy scale had a single latent variable and 13 items, and the behavioral capability scale had a single latent variable and 19 items. …”
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Molecular mechanisms of the anchang group prescription in treating radiation enteritis: network pharmacology analysis and experimental evidence by Wei Liang, Bo Li, Yuehong Sun, Dapeng Jia, Tingting Hu, Rujing Huang, Zhilong Liu, Huan Yang, Baocai Chen, Xiaoming Yin, Xinying He, Yunchuan Sun

“…Although Masson staining showed no significant differences, H&amp;E staining indicated that radiation-induced mucosal damage, including extensive ulcer formation, inflammatory cell infiltration, crypt structure destruction, and epithelial layer injury, could all be ameliorated by ACZF. …”
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Screening and characterization of the scFv for chimeric antigen receptor T cells targeting CEA-positive carcinoma by Chengcheng Zhang, Linling Wang, Qianzhen Zhang, Junjie Shen, Xia Huang, Meiling Wang, Yi Huang, Jun Chen, Yanmin Xu, Wenxu Zhao, Yanan Qi, Yunyan Li, Yanjiao Ou, Zhi Yang, Cheng Qian

“…Therefore, this study aimed to identify the optimal scFv and investigate its biological functions to further optimize the therapeutic potential of CAR-T cells targeting CEA-positive carcinoma.MethodsWe screened four reported humanized or fully human anti-CEA antibodies (M5A, hMN-14, BW431/26, and C2-45), and inserted them into a 3rd-generation CAR structure. We purified the scFvs and measured the affinity. …”
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CircASH1L inhibits ferroptosis and enhances cisplatin resistance by sponging miR-515-5p to regulate cell cycle-related CDCA7/RRM2 in ovarian cancer cells by Lu Feng, Xinru Zou, Longyu Tang, Yijun Yuan, Tianwen He, Bin Su, Ying Tang, Jiang Wang, Kang Liu, Jun Li

“…Circular RNAs (circRNAs) are a class of non-coding RNAs with a circular structure and have been implicated in regulating ferroptosis and chemoresistance. …”
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Epicardial Adipose Tissue and Heterogeneity Parameters Combined with Inflammatory Cells to Predict the Value of Heart Failure with Preserved Ejection Fraction Patients Post Myocard... by Yu-jiao Song, Xiao-ying Zhao, Lu-jing Wang, Ting Ning, Ming-tian Chen, Pei Liu, Si-wen Chen, Xin-xiang Zhao

“…The cohort was stratified into two groups: those without HFpEF and those who developed HFpEF.Cardiac structure, function, EAT volume, and infarct volume parameters were obtained using the CMR post-processing software CVI-42, while EAT heterogeneity parameters entropy were derived using Python software. …”
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Adaptación, validación e invarianza factorial de una escala para evaluar la calidad de los cursos virtuales desarrollados para estudiantes peruanos de ciencias de la salud durante... by Claudio Intimayta-Escalante, Rubí Plasencia-Dueñas, Janeth N. Nuñez-Lupaca, Kevin Flores-Lovon, Nancy Ramirez-Bernuy, Giancarlo Pares-Ballasco, Natalia Barrientos-Odias, Ronald Castillo-Blanco

“…Validity based on internal structure was assessed with the Goodness of Fit Indices (GFI) in the Confirmatory Factor Analysis (CFA), considering adequate the comparative fit index (CFI) and the Tucker-Lewis index (TLI) greater than 0.90, as well as values of the standardized root mean square residual (SRMR) and root mean square error of approximation (RMSEA) less than 0.08. …”
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粒径对平底筒仓中心卸料的流态 及仓壁压力分布的影响Influence of particle size on the flow pattern and wall pressure distribution of central discharge in flat-bottom silo... by 杨世明1,刘克瑾2,姚辉江2,黄硕硕2,杜春来1,章敬波1 YANG Shiming1, LIU Kejin2, YAO Huijiang2, HUANG Shuoshuo2, DU Chunlai1, ZHANG Jingbo1

“…In practical engineering, the impact of particle size on silo structure safety should be considered.…”
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Dynamic changes and future trend predictions of the global burden of anxiety disorders: analysis of 204 countries and regions from 1990 to 2021 and the impact of the COVID-19 pande... by Si Chen, Wei Huang, Min Zhang, Yan Song, Chunshan Zhao, Hongwei Sun, Yanyu Wang, Jihong Wang, Yali Sun, Lei Zhou, Yan Zhu, HongYuan Wang, ZhengYang Xu, YuRui Bai, Cheng Chang

“…This study aims to present the Age-Standardized Prevalence Rates (ASPR), Age-Standardized Incidence Rates (ASIR), and disability-adjusted life years (DALYs) associated with anxiety disorders from 1990 to 2021 across 204 countries and regions, emphasizing the age structure and the disease burden following the pandemic. …”
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The institutional future of Brussels by Alain Maskens, Nicolas Lagasse, Jeroen Van Nieuwenhove, Hugues Dumont

“…At the end of his review it seems to him that these goals would be served better by a reasonable evolution of the current structure than by the far-reaching reforms that the manifesto proposes. …”
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