Isobutyrate Confers Resistance to Inflammatory Bowel Disease through Host–Microbiota Interactions in Pigs by Xiuyu Fang, Haiyang Liu, Junling Liu, Yongqing Du, Zihan Chi, Yiqi Bian, Xuan Zhao, Teng Teng, Baoming Shi

“…We speculate that isobutyrate may play a crucial role in regulating host gut homeostasis. We established a model of dextran sulfate sodium-induced colitis in pigs, which have gastrointestinal structure and function similar to those of humans; we performed multiomic analysis to investigate the therapeutic effects and potential mechanisms of isobutyrate on IBD at both the animal and cellular levels and validated the results. …”
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FNDC3B promotes gastric cancer metastasis via interacting with FAM83H and preventing its proteasomal degradation by Yuying Zhang, Lingyu Ran, Yuying Liu, Wei Li, Ai Ran, Haiping Li, Bo Huang, Junwu Ren, Hao Ning, Qiang Ma, Xiaolin Wang, Feifei Yang, Xiaojuan Pan, Ce Liang, Shimin Wang, Changhong Qin, Yan Jiang, Kun Qian, Bin Xiao

“…Functionally, elevated FNDC3B promoted GC metastasis both in vitro and in vivo. Structurally, the proline-rich N-terminus and a transmembrane (TM) domain at the C-terminus were crucial for maintaining the metastasis function of FNDC3B. …”
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Prostate cancer and metabolic syndrome: exploring shared signature genes through integrative analysis of bioinformatics and clinical data by Maomao Guo, Sudong Liang, Zhenghui Guan, Jingcheng Mao, Zhibin Xu, Wenchao Zhao, Hao Bian, Jianfeng Zhu, Jiangping Wang, Xin Jin, Yuan Xia

“…Abstract The incidence of both prostate cancer (PCa) and metabolic syndrome (MS) has been steadily increasing due to changes in population structure and lifestyle. These two conditions frequently co-occur, yet their shared pathogenic mechanisms remain unclear. …”
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Genomic architecture of purebred and crossbred Moghani lambs with Texel and Booroola sheep by Reza Talebi, Mohsen Mardi, Mehrshad Zeinalabedini, Tomasz Szmatoła, Mehrbano Kazemi Alamouti, Seyyedeh Azadeh Javadi Taklimi, Mohammad Reza Ghaffari

“…Genotyping-by-sequencing (GBS) was used to assess genetic diversity, admixture patterns, and selection signatures. Structure analysis revealed complex admixture in BMM and BRM, while TDM and TTM were more homogeneous. …”
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Complex Variation in Afrotropical Mammal Communities With Human Impact by Deogratias Tuyisingize, Lars Kulik, Delagnon Assou, Diorne Zausa, Solange Kamga, Onella Mundi, Stefanie Heinicke, Inza Kone, Samedi Jean Pierre Mucyo, Tenekwetche Sop, Christophe Boesch, Colleen Stephens, Anthony Agbor, Samuel Angedakin, Emma Bailey, Mattia Bessone, Charlotte Coupland, Josephine Head, Tobias Deschner, Paula Dieguez, Villard Ebot Egbe, Anne‐Céline Granjon, Thurston Cleveland Hicks, Sorrel Jones, Ammie K. Kalan, Kevin E. Langergraber, Juan Lapuente, Kevin C. Lee, Laura K. Lynn, Nuria Maldonado, Maureen S. McCarthy, Amelia Meier, Lucy Jayne Ormsby, Alex K. Piel, Lilah Sciaky, Volker Sommer, Fiona A. Stewart, Erin G. Wessling, Jane Widness, Roman M. Wittig, Pauline Strohbach, Mimi Arandjelovic, Yntze van derHoek, Hjalmar S. Kühl

“…We assessed variation in the structure and composition of Afrotropical medium and large mammal communities within and outside protected areas, and under varying human impact. …”
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Analysis of InAs/InAsSb Superlattice Miniband Positions for a Cascade LWIR Detector by K. Murawski, K. Majkowycz, K. Michalczewski, J. Jurenczyk, L. Kubiszyn, T. Manyk, M. Kopytko, B. Seredynski, P. Martyniuk

“…The results collected based on the photoluminescence (PL) and spectral response (SR) measurements were combined with theoretical calculations using the (<inline-formula> <tex-math notation="LaTeX">$8\times 8$ </tex-math></inline-formula> Hamiltonian) k<inline-formula> <tex-math notation="LaTeX">$\cdot $ </tex-math></inline-formula>p model for both strained and strain-free structure. …”
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Long term emission and simulation on air quality from residential coal burning in China by Qin Yan, Tingyu Xiao, Wenjie Zhang, Shaofei Kong, Yuzhe Zhang, Qingxian Gao, Yun Shu, Hui Li, Han Wang

“…To address this, a suite of control policies has been implemented, leading to a shift in the energy structure and a limitation in pollution emission within RCB sector. …”
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Polarization-independent high-sensitive metamaterial sensor for chemical sensing and EMI shielding application by Md Kutub Uddin, Shawon Hossen, Touhidul Alam, Mohammad Tariqul Islam, Saleh Albadran, Haitham Alsaif, Ahmed S. Alshammari, Ahmed Alzamil, Mohammad Lutful Hakim

“…Besides, the unit cell structure can be utilized as a sensor for detecting different liquid chemical substances. …”
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Short-term PM1 exposure and sleep duration: a nationwide study using consumer-grade wearable devices by Jiajun Liu, Mintao Su, Junxiong Ma, Qinfeng Zhou, Hanxu Shi, Yujie Shi, Shuyu Huang, Yuchuan Tang, Peining Zhou, Kunyao Yu, Rui Su, Rui Zhou, Jing Wei, Jing Ma, Zhenyu Zhang

“…Although individual sleep duration changes appear modest, the cumulative impact of PM _1 on sleep structure, especially in vulnerable populations, poses significant public health risks in physiological restoration. …”
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Building a collaborative ecosystem across the IDeA-CTR networks in response to a public health emergency by A. Jerrod Anzalone, Sharon Patrick, Amber Abel, Brad Price, Elizabeth Reisher, Kent Ripplinger, Mary Emmett, Ronald Horswell, San Chu, William B. Hillegass, Francisco S. Sy, Brian Melancon, H. Timothy Bunnell, Lucio Miele, Mary Helen Mays, Joseph Keawe‘aimoku Kaholokula, Elizabeth S. Chen, Karen M. Crowley, Indra Neil Sarkar, Susan L. Santangelo, Clifford J. Rosen, Jeremy Harper, David Bard, William Beasley, Sally L. Hodder

“…Methods: We developed an organizational structure across the IDeA-CTRs to improve research productivity in resource-challenged areas of the U.S. …”
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Women’s and girls’ sexual empowerment differs by geographical context: a population-based validation study by Shannon N. Wood, Jessica L. Dozier, Celia Karp, Funmilola M. OlaOlorun, Elizabeth Omoluabi, Rosine Mosso, Pierre Z. Akilimali, Simon Peter Sebina Kibira, Frederick Makumbi, Georges Guiella, Peter Gichangi, Anoop Khanna, Sani Oumarou, Caroline Moreau

“…Overall scores of the validated measures were descriptively examined across settings. Findings Final models confirm the theoretical structure of the sexual empowerment measure, including two- dimensions: “existence of choice” and “exercise of choice”, each comprised of three items, with moderate internal consistency ranging from 0.59 to 0.69. …”
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A 1.2-V, 106.4-dB DR Discrete-Time Sigma-Delta Modulator With Feedback Adaptive Cascaded Integrator for Sensor Applications by Ghayur Hussain, Nguyen van Quang, Muhammad Basim, Chang Hyeon Kim, Nabeel Ahmad, Sung June Byun, Kang-Yoon Lee

“…The structure exhibits an exceptional dynamic range (106.4dB) and 17.38-bit ENOB across 1.95 KHz bandwidth at 2 MHz sampling. …”
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Neutrophil pyroptosis regulates corneal wound healing and post‐injury neovascularisation by Peng Chen, Zhentao Zhang, Lilian Sakai, Yanping Xu, Shanzhi Wang, Kyung Eun Lee, Bingchuan Geng, Jongsoo Kim, Bao Zhao, Qiang Wang, Haitao Wen, Heather L. Chandler, Hua Zhu

“…Abstract Rationale The cornea is a unique structure that maintains its clarity by remaining avascular. …”
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Investigating alginate and chitosan electrospun nanofibers as a potential wound dressing: an in vitro study by Sharjeel Abid, Ling Wang, Md. Kaiser Haider, Gopiraman Mayakrishnan, Rajamani Lakshminarayanan, Kyu Oh Kim, Azeem Ullah, Ick Soo Kim

“…Both sodium alginate (SA-L) and chitosan (CS-L) nanofibers were successfully produced with a homogeneous and defect-free structure. XRD and FTIR analyses were conducted to validate the incorporation of Lev in the nanofibers. …”
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SaeR as a novel target for antivirulence therapy against Staphylococcus aureus by Peng Gao, Yuanxin Wei, Suying Hou, Pok-Man Lai, Han Liu, Sherlock Shing Chiu Tai, Victor Yat Man Tang, Pradeep Halebeedu Prakash, Kong-Hung Sze, Jonathan Hon Kwan Chen, Hongzhe Sun, Xuechen Li, Richard Yi-Tsun Kao

“…When Glu159 was changed to Asn, the bacteria developed resistance to HR3744. A structure–activity relationship study revealed that a molecule with a slight modification did not inhibit SaeR, indicating the selectivity of HR3744. …”
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Older people and stroke: a machine learning approach to personalize the rehabilitation of gait by Elvira Maranesi, Federico Barbarossa, Leonardo Biscetti, Marco Benadduci, Elisa Casoni, Ilaria Barboni, Fabrizia Lattanzio, Lorenzo Fantechi, Daniela Fornarelli, Enrico Paci, Sara Mecozzi, Manuela Sallei, Mirko Giannoni, Giuseppe Pelliccioni, Giovanni Renato Riccardi, Valentina Di Donna, Roberta Bevilacqua

“…Results indicated ML models could identify stroke types based on gait variables when traditional tests could not. …”
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Dark Star Clusters or Ultrafaint Dwarf Galaxies? Revisiting UMa3/U1 by Ali Rostami-Shirazi, Hosein Haghi, Akram Hasani Zonoozi, Pavel Kroupa

“…To assess whether UMa3/U1 is a DSC, we conducted direct N -body simulations and identified a model that successfully reproduces both its compact structure and elevated M _Dyn / L , supporting a self-gravitating cluster origin. …”
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Fire history and treeline elevation in the Apennines: insights from pedo-anthracological analysis on Monte Cervati, Southern Italy by Giuliano Bonanomi, Giuliano Bonanomi, Adriano Stinca, Giandomenico Amoroso, Emilia Allevato, Giuseppina Iacomino, Gianluigi Mauriello, Riccardo Motti, Alfredo Nicastri, Francesca Bellucci, Mohamed Rida Abelouah, Luigi Di Costanzo, Mohamed Idbella

“…Charcoal analysis identified remains from herbaceous (Dactylis), shrubs (Daphne), and trees (F. sylvatica), indicating that past vegetation consisted of wooded grassland.ConclusionsHistorical fire events likely played a crucial role in shaping the current treeline structure by eliminating the arboreal component and promoting the establishment of a predominantly herbaceous landscape. …”
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Ancillary Voltage Control Design for Adaptive Tracking Performance of Microgrid Coupled With Industrial Loads by Subrata K. Sarker, Shahriar Rahman Fahim, Niloy Sarker, Kazi Zakaria Tayef, Abu Bakar Siddique, Dristi Datta, M. A. Parvez Mahmud, Md. Fatin Ishraque, Sajal K. Das, Md Rabiul Islam Sarker, Sk. A. Shezan, Ziaur Rahman

“…Secondly, we propose a novel fixed control structure named model reference modified fractional-order PID (MR-F0PID) regulator to maintain the high tracking response of the MG via the control of inverter associated with the SNs. …”
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Healthy Cardiovascular Status Attenuates the Detrimental Association Between Osteosarcopenic Adiposity and Alzheimer's Disease‐Related Dementia: A UK Biobank Cohort Study by Wenxu Wang, Rui Ren, Honghao Yang, Jinguo Jiang, Xingyue Ye, Chenying Wang, Xiang Ji, Wen Li, Yuhong Zhao, Yang Xia, Difei Wang

“…The hazard ratios (HRs) and 95% CIs for ADRD were estimated using Cox proportional hazards models. A secondary analysis included 14 750 participants with brain magnetic resonance imaging data to explore the role of brain structure in the association between OSA and the incidence of ADRD. …”
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