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57881
BD-WNet: Boundary Decoupling-Based W-Shape Network for Road Segmentation in Optical Remote Sensing Imagery
Published 2025-01-01“…Different from other segmentation tasks, road segmentation typically faces unpredictable structure, irregular distribution, and complex background interference. …”
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57882
Adipose stem cells regulate lipid metabolism by upregulating mitochondrial fatty acid β-oxidation in macrophages to improve the retention rate of transplanted fat
Published 2024-09-01“…Graft retention, tissue structure, fibrosis, macrophage phenotype transformation, lipid deposition, mitochondrial morphology, oxygen consumption rate (OCR), fatty acid β-oxidation (FAO) level, and ATP production were assessed. …”
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57883
L-methionine promotes CD8+ T cells killing hepatocellular carcinoma by inhibiting NR1I2/PCSK9 signaling
Published 2025-06-01“…However, small molecule inhibitors are lacking due to its flat protein structure. Methods: PCSK9 transcription inhibitor screening was conducted using a PCSK9 promoter-driven td-Tomato plasmid. …”
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57884
T330M Substitution in the Sodium-Dependent Phosphate Transporter NaPi2b Abolishes the Efficacy of Monoclonal Antibodies Against MX35 Epitope
Published 2025-04-01“…However, variations in the NaPi2b protein structure may limit the efficacy of therapeutic antibodies by affecting the accessibility of the MX35 epitope. …”
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57885
The intersection between circulatory microRNAs and biomarkers of neurodegeneration
Published 2025-07-01“…To account for the high-dimensional structure of miRNAs, we repeated the analysis using elastic net regularization models. …”
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57886
Assessing the Impact of Distance Traveled and Birth Volumes of Hospital Maternity Units on Newborn Outcomes: Population-Based Cohort Study
Published 2025-01-01“…Given the hierarchical structure of our data (births nested within hospitals), we employed log-binomial regression models with random intercepts to estimate relative risks and 95% CIs for evaluating the association between HMU volumes (≥1500 births/year) and RTD (<5 km) with the risk of being transferred and/or death after birth (primary outcome). …”
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57887
Estudio preliminar para el diseño de una máquina productora de bloques con suelos estabilizados. // Preliminary study for the design of a block machine producer with stabilized soi...
Published 2006-09-01“…The schemes, cinematic and<br />structure of the machine, were made starting from the analysis of similar equipment and of own ideas. …”
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57888
Fractal characteristics of spontaneous combustion of gas-bearing coal under different temperature and adsorption pressure conditions
Published 2025-05-01“…To study the disaster mechanism of the composite disaster of gas and coal spontaneous combustion, the experiments of low-temperature oxidation microstructure and thermal analysis of coal under different CH4 adsorption pressures were carried out in the paper by low-temperature liquid nitrogen adsorption, scanning electron microscopy and TG-FTIR testing methods, and a pore fractal calculation model was set up based on the fractal theory to investigate the influence of adsorbed CH4 on the pore structure and thermal stability of coal. …”
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57889
Estudio preliminar para el diseño de una máquina productora de bloques con suelos estabilizados. // Preliminary study for the design of a block machine producer with stabilized soi...
Published 2005-01-01“…The schemes, cinematic and<br />structure of the machine, were made starting from the analysis of similar equipment and of own ideas. …”
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57890
MRI of tumor T cell infiltration in response to checkpoint inhibitor therapy
Published 2020-05-01“…Here, we proposed an innovative concept that a sufficiently large influx of tumor infiltrating T cells, which have a smaller diameter than cancer cells, will change the diameter distribution and decrease the average size of cells within a volume to a degree that can be quantified by non-invasive MRI.Methods We validated our hypothesis by studying tumor response to combination immune-checkpoint blockade (ICB) of anti-PD-1 and anti-CTLA4 in a mouse model of colon adenocarcinoma (MC38). The response was monitored longitudinally using Imaging Microstructural Parameters Using Limited Spectrally Edited Diffusion (IMPULSED), a diffusion MRI-based method which has been previously shown to non-invasively map changes in intracellular structure and cell sizes with the spatial resolution of MRI, in cell cultures and in animal models. …”
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57891
miR-21 and Pellino-1 Expression Profiling in Autoimmune Premature Ovarian Insufficiency
Published 2020-01-01“…Autoimmune POI mouse models were established by ZP3 immunization. Serum miR-21, Peli1 mRNA of peripheral blood mononuclear cells (PBMCs) and regulatory T cells (Tregs), general status, spleen Tregs ratio, inflammatory factors, ovarian endocrine function, and ovarian structure were evaluated. …”
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57892
Estimating the Intra-Puparial Period of <i>Chrysomya nigripes</i> Aubertin Using Morphology and Attenuated Total Reflection Fourier Transform Infrared (ATR-FTIR) Spectroscopy
Published 2025-05-01“…In this study, each sub-stage of the <i>C. nigripes</i> pupa and the time range of structure emergence were recorded, and it was concluded that the spectral trends were time-dependent. …”
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57893
Predictability of Air Pollutants Based on Detrended Fluctuation Analysis: Ekibastuz Сoal-Mining Center in Northeastern Kazakhstan
Published 2025-07-01“…Long-term memory is recorded in the structure of all the time series of air pollution indicators. …”
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57894
The determination methodology for optimal stemming length of deep-hole blasting for hard roof cutting in coal mines
Published 2025-05-01“…In addition, based on Livingston’s blasting funnel theory and combined with the charging structure, the top plate deep borehole charging blasting funnel model was established, and the borehole sealing length calculation method based on the “maximum internal blasting effect” of explosives was obtained. …”
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57895
Human Serum Albumin and Human Serum Albumin Nanoparticles as Carriers of 10-(2′-Pyrimidyl)-3,6-diazaphenothiazine: In Vitro Spectroscopic Studies
Published 2025-01-01“…High encapsulation efficiency of 10-Pyr-3,6-DAPT into the HSA-NPs was obtained, and the changes in albumin secondary structure due to the presence of 10-Pyr-3,6-DAPT were registered. …”
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57896
Development of a formative index for precarious employment in Denmark
Published 2025-07-01“…Exploratory factor analysis was conducted to explore factor structure of the PE Index. To assess reliability and inter-item correlation of the individual dimensions, Cronbach's Alpha and Kendall's Tau were applied. …”
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57897
INSTITUTIONAL GLOBALIZATION AS A SYSTEM OF INTEGRATION THE PHENOMENON OF THE POSTMODERN DEVELOPMENT
Published 2015-12-01“…Policy enhancing the role of human rights and the development of the principle of subjectivity means deepening the democratic foundations of the state structure. In the social sphere the subjectivity is expressed in the individualization of the social existence of man and the personification of public relations and it is implemented through the mechanisms of liberal institutions. …”
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57898
Self-Nanoemulsifying Drug Delivery System of Morin: A New Approach for Combating Acute Alcohol Intoxication
Published 2024-10-01“…Jiamin Mao,1,2 Xiaoyuan Liu,2 Lie Zhang,1 Yu Chen,2 Shiyu Zhou,2 Yujiao Liu,2 Jing Ye,2 Xiaohong Xu,2 Quan Zhang1– 4 1Department of Neurosurgery, The First Affiliated Hospital of Chengdu Medical College, Chengdu, 610500, People’s Republic of China; 2Sichuan Higher Education Institute Key Laboratory of Structure-Specific Small Molecule Drugs, Institute of Materia Medica, School of Pharmacy, Chengdu Medical College, Chengdu, 610500, People’s Republic of China; 3Development and Regeneration Key Laboratory of Sichuan Province, Department of Anatomy and Histoembryology, Chengdu Medical College, Chengdu, 610500, People’s Republic of China; 4Chengdu Nature’s Grace Biological Technology Co., Ltd., Chengdu, 610213, People’s Republic of ChinaCorrespondence: Quan Zhang, Email zhangquancdmc@126.comPurpose: Acute alcohol intoxication (AAI) is a life-threatening medical condition resulting from excessive alcohol consumption. …”
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57899
A novel MIR100HG transcript enhances tumorigenesis by inducing BCLAF1-mediated alternative splicing in colorectal cancer
Published 2025-07-01“…Conclusions Our study reveals a novel MIR100HG transcript induced by TGFβ/SMAD signaling and explores its distinct oncogenic mechanism through a structure-specific interaction with the BCLAF1. These findings suggest distinct MIR100HG transcripts may exert diverse functions and lead to the identification of novel molecular markers and therapeutic targets for CRC.…”
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57900
Educational technologies in the system of managerial staff mentoring
Published 2016-12-01“…It is practically impossible to create a large-scale system of continuous development of managerial staff in the organizations without continuous interaction of personnel services in organizations, and educational institutions that have, both human and educational technologies.It is proposed to extend the learning process of the educational institutions in the state bodies and organizations through a system of cascading mentoring based on telecommunication technologies. The structure of the e-learning system provides means of creation, management and delivery of the content, means of organizing the learning process and interaction support of the participants. …”
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