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57741
Early childhood caries predictors
Published 2021-01-01“…According to the full structure, there were 49.6% of boys and 50.4% of girls. …”
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57742
B-Cell Epitope Mapping of the <i>Treponema pallidum</i> Tp0435 Immunodominant Lipoprotein for Peptide-Based Syphilis Diagnostics
Published 2025-06-01“…Recognized amino acid sequences were then mapped to the experimentally determined Tp0435 structure. <b>Results:</b> Reactive epitopes in both serum groups mapped predominantly to the α-helix preceding Tp0435 soluble β-barrel and the loops of the barrel. …”
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57743
Safety, Tolerability, and Immunogenicity of a DNA Vaccine (pGX9501) Against SARS-CoV-2 in Healthy Volunteers: A Single-Center, Randomized, Double-Blind, Placebo-Controlled, and Dos...
Published 2025-05-01“…Variations in the microbiome structure suggested a tangible impact of the gut microbiota on vaccine immunogenicity. …”
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57744
Bidirectional associations among positive affect, anhedonia and meaning in life during major depressive episode: ecological momentary assessment study in unipolar and bipolar indiv...
Published 2025-07-01“…Method Participants (N = 88, mean age 28.7 years, 69% female), including individuals with MDD (n = 29) and MDE/bipolar disorder (n = 29) and healthy controls (n = 30), were assessed for positive affect, pleasure and MIL 5 times daily over a 2-week period. Multilevel modelling analysis was conducted, with estimation of first-order autoregressive model structure and time-lagged relationship between pleasure and positive affect. …”
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57745
Engagement and Stress Concentration Evaluation of a Novel Two-Part Compression Screw: A Preliminary Finite Element Analysis
Published 2025-05-01“…<b>Background/Objectives:</b> This novel compression screw design offers potential benefits due to its two-part structure and can be used for various bone types, much like a conventional single-piece compression screw. …”
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57746
FMO2+ cancer-associated fibroblasts sensitize anti-PD-1 therapy in patients with hepatocellular carcinoma
Published 2025-05-01“…FMO2+ CAFs increase anti-PD-1 treatment efficacy by promoting tertiary lymphoid structure formation and increasing the infiltration of CD8+ T cells and M1-like macrophages through the C-C motif chemokine ligand 19 (CCL19)-C-C motif chemokine receptor 7 axis. …”
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57747
Differential effects of electroacupuncture and manual acupuncture on spontaneously hypertensive rats: insights from intestinal microbiota and metabolomics
Published 2025-07-01“…EA and MA influence the composition of intestinal microbiota in SHRs, aligning the microbial structure more closely with that of the WKY group. …”
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57748
Quantitative sensory testing in dogs with spontaneous osteoarthritis
Published 2025-04-01“…Feasibility for performing the tests was assessed for the final 45 dogs recruited to the study. The hierarchical structure of the QST testing data was accounted for within the statistical analysis by employing general linear modelling within a multilevel modelling framework using the MLwiN statistics package.ResultsOsteoarthritis category was not a major determinant of QST outcome measures for the majority of modalities evaluated. …”
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57749
Inactivation of Tnf‐α/Tnfr signaling attenuates progression of intervertebral disc degeneration in mice
Published 2024-12-01“…Conclusion The deletion of Tnfr mitigates age‐related and LSI‐induced IVDD, as evidenced by preserved IVD structure, and improved ECM integrity. These findings suggest a crucial role of Tnf‐α/Tnfr signaling in IVDD pathogenesis in mice. …”
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57750
Succinimidyl Alginate-Modified Fibrin Hydrogels from Human Plasma for Skin Tissue Engineering
Published 2025-07-01“…The mechanical and microstructure properties of these new hydrogels were evaluated, as were their biocompatibility and potential to create 3D skin models in vitro. Dermo-epidermal skin cultures with primary human fibroblast and keratinocyte cells on these matrices showed improved dermal stability and better tissue structure, particularly SA concentrations of 0.5 and 1 mg/mL, as confirmed by H&E (Hematoxylin and Eosin) staining and immunostaining assays. …”
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57751
S-propargyl-cysteine attenuates temporomandibular joint osteoarthritis by regulating macrophage polarization via Inhibition of JAK/STAT signaling
Published 2025-04-01“…Results SPRC significantly alleviated cartilage and bone damage in the TMJ-OA rat model, as demonstrated by improved bone volume and cartilage structure. …”
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57752
Organic material mulching regulated core microbial groups to promote soil carbon and nitrogen cycling and improve faba bean productivity under a triple-cropping system in purple so...
Published 2025-07-01“…BackgroundIntensive agricultural production leads to the reduction of soil carbon (C) and nitrogen (N) reserves, and organic material mulching (OMM) can improve microbial community structure and promote C and N accumulation. The multi-cropping system based on legumes can provide abundant organic mulching material and improve soil quality, but the mechanism by which OMM provides ecological benefits via C and N cycling in this system is still unclear.MethodsIn this study, a field experiment of organic mulch under the triple-cropping system of faba bean (Vicia faba L.)…”
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57753
Fecal microbiota transplantation alleviates cognitive impairment by improving gut microbiome composition and barrier function in male rats of traumatic brain injury following gas e...
Published 2024-11-01“…FMT improved intestinal structure and up-regulated expression of tight junction proteins Claudin-1, Occludin, and ZO-1, potentially contributing to its protective effects on both brain and gut.ConclusionTransplantation of gut microbiota from healthy rats significantly enhanced cognitive function in male rats with traumatic brain injury caused by a gas explosion, through the modulation of gut microbiome composition and the improvement of both gut and brain barrier integrity via the gut-brain axis. …”
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57754
A Representation-Learning-Based Graph and Generative Network for Hyperspectral Small Target Detection
Published 2024-09-01“…Firstly, a Graph Convolutional Network (GCN) module better models the non-local topological relationship between samples to represent the hyperspectral scene’s underlying data structure. …”
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57755
SYNTHESIS, ANTIAGGREGATION AND ANTITROMBOTIC ACTIVITIES OF NEW DERIVATIVES OF HYDROXYBENZOIC ACIDS WITH TAURIC FRAGMENT
Published 2021-08-01“…In vitro studies were carried out on the model of ADP-induced platelet aggregation according to the Born G. methods modified by V.A. …”
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57756
PENGEMBANGAN HANDBOOK STRATEGI PEMBELAJARAN INOVATIF UNTUK MENINGKATKAN KOMPETENSI GURU HOMESCHOOLING DI KOTA BANDUNG [THE DEVELOPMENT OF AN INNOVATIVE LEARNING STRATEGY HANDBOOK T...
Published 2025-07-01“…The Design stage focused on creating the handbook structure and content, covering "Mengenal Homeschooling" (Understanding Homeschooling) and "Strategi Pembelajaran Inovatif," which includes personalized learning, project-based learning, inquiry-based learning, and technology integration. …”
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57757
Morphometric changes in the heart of rats with alloxan and streptozotocin diabetes
Published 2024-12-01“…In this regard, of undoubted interest is the study of the relationships between the frequency, structure, and severity of pathogenetic morphometric disorders of the heart in animals with experimental models of alloxan and streptozotocin diabetes. …”
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57758
Numerical simulation of hydrogen adsorption and dissociation mechanisms on the surface of high-grade steel
Published 2025-06-01“…These models were employed to investigate hydrogen adsorption behaviors across different close-packed planes, adsorption sites, and adsorption angles. …”
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57759
Network Embeddedness of Knowledge Production Among International Academic Migrants in China
Published 2025-02-01“…This study examined network embeddedness in knowledge production by combining the "buzz-pipeline" framework with strong- and weak-tie models, focusing on the structure and characteristics of three types of collaborative networks: local buzz collaborations, domestic pipeline collaborations, and international pipeline collaborations. …”
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57760
System architecture and key technologies of intelligent, safe and efficient mining for rockburst coal seams
Published 2024-12-01“…First of all, digital twin technology is used to build a fine digital model, deeply detect and analyze the geological structure of the area where the mine is located, accurately measure the characteristics of the regional geostress field and the physical and mechanical properties of coal and rock, and rely on advanced algorithms to carry out engineering distribution of formation change information to achieve “transparency” of geological information. …”
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