Discovery of natural scaffolds as HER2 inhibitors for breast cancer: virtual screening, molecular dynamics, and biological characterization with selectivity profiling by Asmaa Hossam, Ingy I. Abdallah, Nadia A. El-Sebakhy, Radwan Alnajjar, Mohamed M. Mohyeldin

“…Abstract Nature offers potential therapeutic candidates for breast cancer (BC), and targeting HER2 signaling presents a promising approach, leveraging the successful history of anticancer drug discovery. Using a structure-based virtual screening workflow, a comprehensive library of natural products (NPs) was screened for potential HER2 binding. …”
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Search of potential antidiabetic drugs in range of 5-(phenoxymethylene)-4-R-1,2,4-triazole-3-thions by Yu. M. Kucheryavyi

“…We have established the dependence of the hypoglycemic effect on the chemical structure. Conclusions. The median effective dose has been calculated for most active compound with probit analysis.…”
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Yugoslav female partisans in World War II by Ivana Pantelić

“…The fact that women, despite the aspirations of the Party to win them over, and in spite of customized organizational structure, were poorly represented in the membership of the Party and its leadership, limited the participation of women during the war. …”
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Individualized spatial network predictions using Siamese convolutional neural networks: A resting-state fMRI study of over 11,000 unaffected individuals. by Reihaneh Hassanzadeh, Rogers F Silva, Anees Abrol, Mustafa Salman, Anna Bonkhoff, Yuhui Du, Zening Fu, Thomas DeRamus, Eswar Damaraju, Bradley Baker, Vince D Calhoun

“…Individuals can be characterized in a population according to their brain measurements and activity, given the inter-subject variability in brain anatomy, structure-function relationships, or life experience. …”
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Preparation of sludge-based biochar and its adsorption performance on tetracycline by Freeman Madhau, Zhenjun Wu, Dongjin Wan, Zihao He, Qingwen Qin, Yanru Li, Rethabile Moteletsana, Chen Xin, Zhisan Lin

“…The physicochemical characteristics of MSBC were thoroughly characterized, revealing a highly developed porous structure, rich in functional groups and distinct crystalline phases. …”
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Histogram of Polarization Gradient for Target Tracking in Infrared DoFP Polarization Thermal Imaging by Jianguo Yang, Dian Sheng, Weiqi Jin, Li Li

“…Finally, the gradient and DoLP sign information are ingeniously integrated to enhance the capability of directional expression, thus providing a new theoretical perspective for polarization mosaic image structure analysis. The experimental results obtained using a self-developed long-wave infrared DoFP polarization thermal imaging system demonstrate that, within the same FBACF tracking framework, the proposed HPG feature descriptor significantly outperforms traditional grayscale {8.22%, 2.93%}, histogram of oriented gradient (HOG) {5.86%, 2.41%}, and mosaic gradient histogram (MGH) {27.19%, 18.11%} feature descriptors in terms of precision and success rate. …”
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US Bipartisan Consensus on China: The Making and the Implementation by V. Yu. Zhuravleva

“…According to the most experts, there is a bipartisan consensus in the United States regarding China: both parties recognize that China poses an existential threat to the United States, its economy, socio-political structure and the role as a global leader. This core conceptual consent represents a clear contrast with the endless battles between Democrats and Republicans in the domestic political arena, blocking any legislative initiatives and the development of a unified sociopolitical agenda for the country. …”
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Novel insights into electrical double layers in carbonate reservoirs under low-salinity water injection using molecular dynamics simulation by Saifali Al-Musawi, Fariborz Rashidi, Sepideh Amjad-Iranagh

“…Abstract Understanding how mineral heterogeneity and brine salinity influence the electrical double layer (EDL) structure is crucial for optimizing low-salinity water injection strategies in carbonate reservoirs. …”
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Effective Mechanisms of State-Legal Regulation in Higher Education: Analysis and Implementation Framework by Guzal Galiakbarova, Muslim Khassenov, Elmira Omarova, Svetlana Zharkenova, Zhamilya Berdiyarova, Sholpan Saimova

“…The study aims to establish a state-legal regulating structure for Kazakhstan's universities using global best practices. …”
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Novel Deep Learning Framework for Evaporator Tube Leakage Estimation in Supercharged Boiler by Yulong Xue, Dongliang Li, Yu Song, Shaojun Xia, Jingxing Wu

“…To address these issues, this study proposes a novel deep learning framework (LSTM-CNN–attention), combining a Long Short-Term Memory (LSTM) network with a dual-pathway spatial feature extraction structure (ACNN) that includes an attention mechanism(attention) and a 1D convolutional neural network (1D-CNN) parallel pathway. …”
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Assessing Fetal Circulatory Changes in Gestational Diabetes via Aortic Isthmus Doppler by Xingxing Chen, Lili Zhang, Jiajia Lu, Lijun Shen

“…Background: Gestational diabetes mellitus (GDM) is a common complication during pregnancy that can negatively impact fetal heart function and structure. This study aimed to investigate the hemodynamic characteristics of the fetal aortic isthmus in patients with GDM using Doppler ultrasound parameters. …”
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Estimating the potential risks of developing clusters in medical industry using various ranking criteria by Y. G. Gertsik

“…The risk assessment algorithm for the medical industry companies’ formation and functioning in a cluster structure is given, based on selected indicators of probable risks and levels of the companies’ development or maturity. …”
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Fine Depicting of Seepage Barrier for Gas Flooding in the Lower Wuerhe Formation Reservoir of the 8th District in China by Zhibin Jiang, Hongming Tang, Rui Shen, Xiaoguang Wang, Wei Zhou, Liming Lian, Lisha Qi, Dan Xie, Chuanchuan Qian, Jie Wang, Xiao Liu, Qiyao Liu

“…The mineral composition, pore throat structure, and physical characteristics of the interlayer rocks were studied by X-ray diffraction (XRD) whole-rock analysis and nuclear magnetic resonance (NMR). …”
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The Turkish Adaptation of the Oxford Utilitarianism Scale by Filiz Kumova, Hasan Galip Bahçekapılı

“…The PFA results revealed a two-factor structure, which is similar to that of the original study, with an explained total variance of 52.5%. …”
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Validity and reliability of the Persian version of the emotional labour scale for nurses by Saeed Barzegari, Elyas Hosseinzadeh Younesi, Kurosh Jodaki, Ibrahim Arpaci, Negar Esmaeelzadeh, Seyed Alireza Hasani

“…Conclusions The Persian version of the ELS with 14 items and a three-factor structure showed satisfactory validity and reliability among Iranian nurses. …”
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Original actions performed by a beginner attacker modify defensive dispersion in small-sided soccer games by Paulo Henrique Borges, Lucas Shoiti Carvalho Ueda, Paulo Vitor de Souza, Maria Eduarda Valente Binda, Juliano Fernandes da Silva, João Ribeiro, José Guilherme

“…Actions that are surprising, rare, or out of the ordinary tend to be valued for their potential to destabilize the opposing defensive structure, altering player dispersion, and creating fragile spaces for the attack. …”
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Development of metacognitive skills of university students as a resource for understanding texts in the learning process by T.V. Borzova, E.N. Kameneva-Liubavskaia

“…The development of methodologies for working with digital and/or hypertexts can be incorporated into the structure of understanding models utilised in the pedagogy of university students.…”
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FocusDet: an efficient object detector for small object by Yanli Shi, Yi Jia, Xianhe Zhang

“…It consists of three parts: backbone, feature fusion structure, and detection head. STCF-EANet was used as the backbone for feature extraction, the Bottom Focus-PAN for feature fusion, and the detection head for object localization and recognition.To maintain sufficient global context information and extract multi-scale features, the STCF-EANet network backbone is used as the feature extraction network.PAN is a feature fusion module used in general object detectors. …”
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Multiclass semantic segmentation for digitisation of movable heritage using deep learning techniques by Giacomo Patrucco, Francesco Setragno

“…Nowadays, one of the most effective solutions is represented by the development of image-based techniques, usually connected to a Structure-from-Motion (SfM) photogrammetric approach. …”
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Prepare for trouble and make it double: Effects of Carpobrotus acinaciformis and Apis mellifera invasion in floral visitor networks by Luiz F. C. Serigheli, Sofia Bacca, Brisa Marciniak, Michele S. Dechoum

“…Our hypothesis is that C. acinaciformis, a melitophilous invasive plant, and A. mellifera, a generalist forager, both influence interaction networks, and that their control can alter network structure. Fieldwork was carried out in the Dunas da Lagoa da Conceição Natural Municipal Park, in southern Brazil, with active searches and collection of bees and flowering plants in areas invaded and uninvaded by C. acinaciformis in year 1 of the study. …”
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