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53041
Deep sphingolipidomic and metabolomic analyses of ceramide synthase 2 null mice reveal complex pathway-specific effects
Published 2025-07-01“…The sphingolipidome contains thousands of structurally distinct sphingolipid (SL) species. This enormous diversity is generated by the combination of different long-chain bases (LCBs), N-acyl chains and head groups. …”
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53042
Empowering knowledge graphs with hybrid retrieval-augmented generation for the intelligent mix scheme of mass concrete
Published 2025-12-01“…Firstly, a total of 1723 mix proportioning records collected from 15 hydropower stations were structurally extracted using a customized data transformation tool. …”
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53043
Development of Women Resilience in the Workplace: A Solution to Break the Glass Ceiling
Published 2024-11-01“…MethodologyThis research is applied in terms of purpose and based on the method of data collection in the category of descriptive-correlational research. …”
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53044
Normalization of tumor vasculature by imiquimod: proposal for a new anticancer therapeutic indication for a TLR7 agonist
Published 2025-02-01“…Imiquimod normalized tumor vasculature both structurally (by reducing vessel tortuosity and increasing pericyte coverage) and functionally (by improving tumor perfusion) in a dose-dependent manner. …”
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53045
The Use of Neural Networks in Distance Education Technologies for the Identification of Students
Published 2021-07-01“…Methods of reviewing scientific literature on the research topic, methods of collecting, structuring and analyzing the information obtained were used as materials and methods.Research results. …”
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53046
Practical Approaches to Patient-Centered Care in Europe: Mixed Methods Study Developing a Conceptual Framework for Comprehensive Cancer Care Networks
Published 2025-07-01“…In this context, comprehensive cancer care networks (CCCNs) provide a new means of structuring and delivering quality cancer care, recognizing each patient’s unique preferences and needs. …”
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53047
THE CONTENT OF FOREIGN LANGUAGE TRAINING FOR NON-LINGUISTIC STUDENTS IN HIGHER EDUCATION IN THE CONTEXT OF CONTEMPORARY CHALLENGES
Published 2025-06-01“…Instruction is supported by a structurally logical sequence of disciplines, ensuring continuity with the content acquired in previously studied courses.…”
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53048
The Ethical Significance of Brain-Computer Interfaces as Enablers of Communication
Published 2025-08-01“…Ethical evaluation must therefore balance the immediate benefits of temporary communicative access against the structural vulnerabilities introduced by uncertain long-term provision. …”
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53049
Development and Application of a Senolytic Predictor for Discovery of Novel Senolytic Compounds and Herbs
Published 2025-06-01“…In the DrugBank database, 98 structurally novel candidate compounds with potential senolytic activity were identified. …”
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53050
Anti-HIV-1 Effect of the Fluoroquinolone Enoxacin and Modulation of Pro-Viral hsa-miR-132 Processing in CEM-SS Cells
Published 2025-01-01“…Results: We established that Enoxacin, but not the structurally similar compound nalidixic acid, exhibits strong anti-HIV-1 effects in the T-cell line CEM-SS, but not MT-4. …”
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53051
Piloting the options assessment toolkit with national malaria programme leaders from the Asia–Pacific countries: a meeting report
Published 2025-06-01“…Thematic analysis of qualitative data revealed that NMPs found the OAT useful and timely for structuring malaria policy discussions. …”
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53052
Engagement of Indigenous peoples in commercial tobacco reform strategies: a scoping review protocol
Published 2025-07-01“…This review supports the global goal of eradicating commercial tobacco-related harms – reframing commercial tobacco use as a structurally imposed harm sustained by colonial and commercial forces rather than personal choice. …”
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53053
The antioxidant property of CAPE depends on TRPV1 channel activation in microvascular endothelial cells
Published 2025-03-01“…Herein, we hypothesized that a subfamily of TRP ion channels works as the molecular entity that recognizes CAPE at the plasma membrane and allows a fast shift in the antioxidant capacity of intact endothelial cells (EC).By monitoring cytoplasmic Ca2+ in a microvascular EC model, we compared the calcium responses evoked by three structurally related compounds: caffeic acid phenethyl ester, neochlorogenic acid and caffeic acid. …”
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53054
Newly diagnosed diseases and the frequency of their occurrence in patients after a new coronavirus infection. Results of an International Register "Dynamics Analysis of Comorbiditi...
Published 2023-05-01“…Demographic, clinical, and laboratory data, computed tomography (CT) results, information about inhospital clinical course and complications of COVID-19 during hospitalization were extracted from electronic health records using a standardized data collection form. …”
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53055
Environmental Impact of Physical Visits and Telemedicine in Nursing Care at Home: Comparative Life Cycle Assessment
Published 2025-04-01“…Telemedicine visits were elementary in nature, such as supporting patients in taking their medication or structuring their daily agenda. We quantified average environmental impacts from cradle to grave, using the Environmental Footprint method, and verified the robustness of the comparison via uncertainty analysis. …”
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53056
Multi-element Accurate Analysis of Sulfide Minerals by Low-temperature Ablation LA-ICP-MS
Published 2023-10-01“…The ablation craters on the chalcopyrite showed a two-layer cyclic structure, in which the inner layer was a light-colored melting zone, and the outer layer was a white aerosol vapor sediment. …”
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53057
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53058
Suppression of the T-dependent antibody response following oral exposure to selected polycyclic aromatic compounds in B6C3F1/N mice
Published 2025-03-01“…Careful characterization of strong positive and clear negative PACs is needed in order to lay the foundation for generating robust immunotoxicity data for structurally diverse PACs that have not yet been evaluated.MethodsIn the current study, adult B6C3F1/N female mice were treated daily for 28 consecutive days by oral administration of B(a)P to provide dose levels ranging between 2 and 150 mg/kg bodyweight/day. …”
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53059
Exploring the Strong Interaction of Three-Body Systems at the LHC
Published 2024-09-01“…The analysis of the p-d correlation shows that only a full three-body calculation that accounts for the internal structure of the deuteron can explain the data. In particular, the sensitivity of the observable to the short-range part of the interaction is demonstrated. …”
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53060
A Rare Case of Exophiala Dermatitidis Isolation in a Patient with Non-Cystic Fibrosis Bronchiectasis: Colonization or True Infection?
Published 2025-06-01“…<b>Discussion:</b> This case underscores the diagnostic challenges in distinguishing fungal colonization from true infection in structurally abnormal lungs. In NCFB, disrupted mucociliary clearance and microbial dysbiosis may facilitate fungal persistence, even in the absence of overt immunosuppression. …”
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