Shifts in the rhizosphere microbiome and exudation profile of avocado (Persea americana Mill.) during infection by Phytophthora cinnamomi and in presence of a biocontrol bacterial... by Frédérique Reverchon, Mariel García-Meléndez, Edgar Guevara-Avendaño, Oscar Mora-Chávez, Itzel A. Solís-García, Wesley Dáttilo, José A. Guererro-Analco, Alfonso Méndez-Bravo, Juan L. Monribot-Villanueva, Violeta Patiño-Conde, Fernando Pineda-García, Eria A. Rebollar

“…The dysbiosis (disturbance of the microbiome structure of healthy plants) caused by these pathogens, combined with the recruitment of beneficial microorganisms by the diseased plant, may cause shifts in the rhizosphere microbiome during the infection process. …”
Get full text

Effector Pt31812 from Puccinia triticina acts as avirulence factor for Lr42-mediated resistance in wheat by Jianyuan Li, Jianyuan Li, Jiali Li, Jie Wei, Jie Wei, Lin Li, Yue Qi, Yue Qi, Yue Zhang, Yue Zhang, Wenxiang Yang, Qian-Hua Shen

“…In the study, Pt31812 was cloned by PCR, and the expression pattern and structure were analyzed by qRT-PCR and online softwares. …”
Get full text

Risk Factors and Prognostic Implications of Tumor‐Related Epilepsy in Diffuse Glioma Patients: A Real‐World Multicenter Study by Yao Xiao, Zhuang Nie, Jinsha Huang, Jie Zhao, Chengjun Dong, Yan Zou, Zikai Li, Bingqing Yan, Yue Hu, Fan Yang, Jong Woo Lee, Alexander P. Lin, Steven Tobochnik, Min Zhou, Ziqiao Lei

“…Multivariate analysis identified age as the only significant independent correlate of TRE in the OD/AC group (OR = 0.961; p = 0.004), while the absence of deep structure involvement was independently associated with TRE in the NOS/NEC and HGG groups. …”
Get full text

Do neonatal intensive care unit (NICU) health workers know about retinopathy of prematurity (ROP)? A qualitative study at a Regional Referral Hospital in Uganda by Henry Muwonge, Innocent Ayesiga, Primrose Magala, Tom Didimus Ediamu, Hana El Diwany, Ian LY Yeung, Alex Wasomoka, Phillip Musoke, Elias Musiime, Abraham Tumwesigye, Pius Atwau, Noreen Atwijukire, Iddi Ndyabawe, Anne Mpaire Musika, Himanshu I Patel, Aeesha NJ Malik, Ibrahim Bwaga, Sheba Gitta Nakacubo

“…We recommend developing a formal training structure and syllabus for ROP screening. The training can enhance task shifting among health workers in areas without specialised health workers. …”
Get full text

A 1.8 m Class Pathfinder Raman LIDAR for the Northern Site of the Cherenkov Telescope Array Observatory—Performance by Pedro José Bauzá-Ruiz, Oscar Blanch, Paolo G. Calisse, Anna Campoy-Ordaz, Sidika Merve Çolak, Michele Doro, Lluis Font, Markus Gaug, Roger Grau, Darko Kolar, Camilla Maggio, Manel Martinez, Samo Stanič, Santiago Ubach, Marko Zavrtanik, Miha Živec

“…The results show that the pBRL can provide valuable scientific results on aerosol characteristics and structure, although not all performance requirements could be validated under the conditions found at the two test sites. …”
Get full text

Butyrate alleviates food allergy by improving intestinal barrier integrity through suppressing oxidative stress‐mediated Notch signaling by Jialu Shi, Wenjun Mao, Yuqing Song, Yuxin Wang, Lili Zhang, Yan Xu, Huiwen Gu, Siyu Yao, Yuanhang Yao, Zhifeng Liu, Vijaya Raghavan, Jin Wang

“…However, butyrate counteracted this loop by restoring microbiota structure and suppressing reactive oxygen species (ROS)/Notch cascades. …”
Get full text

Identification, Characterization, Expression Profiling and Functional Analysis of Tobacco <i>CalS</i> Gene Family by Hong Wang, He Meng, Xiaohan Qi, Yi Pan, Bailu Ji, Liuying Wen, Yanjun Zan, Huan Si, Yuanying Wang, Dan Liu, Aiguo Yang, Zhengwen Liu, Lirui Cheng

“…A comprehensive analysis of their physicochemical properties, gene structure, and evolutionary history highlighted their evolutionary conservation. …”
Get full text

Lupus nephritis and U1-RNP-antibodies are associated with low bone mineral density and osteoporosis in patients with systemic lupus erythematosus: baseline findings in a sub-cohort... by Edgar Wiebe, Elisa Celine Schilling, Dörte Huscher, Andriko Palmowski, Zhivana Boyadzhieva, Sandra Hermann, Burkhard Muche, Mirella Lopez Picazo, Gerhard Krönke, Falk Hiepe, Tobias Alexander, Frank Buttgereit

“…Our findings suggest that 3D bone structure analysis may be helpful in discriminating past vertebral fractures. …”
Get full text

A computational DNA methylation method to remove contaminated DNA from spent embryo culture medium for noninvasive preimplantation genetic testingResearch in context by Yidong Chen, Jin Huang, Fuchou Tang, Lu Wen, Jie Qiao

“…At the heart of ART success is preimplantation genetic testing (PGT), which enables the detection of chromosomal anomalies, single-gene disorders, and structural rearrangements, enhancing embryo selection and mitigating genetic risk. …”
Get full text

Same same but different: Neuroanatomic and connectomic profiles of early-onset schizophrenia and autism spectrum disorder by Bin Lu, Xue Li, Xue-Ping Gao, Jing Chen, Yi Liu, Jian-Ping Lu, Siu-Ching Kat, Zeng-Hui Ma, Li-Yang Zhao, Ting-Ni Yin, Xing Su, Fan-Chao Meng, Ya-Ru Zhang, Shu-Xian Wu, Wen-Jie Yan, Ya-Song Du, Xue-Rong Luo, Jing Liu, Chao-Gan Yan

“…Conclusion: The neuro-profiles revealed that EOS and ASD exhibit overlapping as well as unique imaging characteristics; however, EOS exhibits greater structural variation, while ASD presents with more subtle connectomic abnormalities. …”
Get full text

全基因组关联分析标准化流程的构建与扩展应用(Development and Extended Applications of Standardized Processes for Genome-Wide Association Studies) by 许喆1，2，石延枫1，2，张杰1，2，姜明慧1，2，刘阳1，2，李昊1，2，3，廖晓凌4，程丝1，2，3(XU Zhe1,2, SHI Yanfeng1,2, ZHANG Jie1,2, JIANG Minghui1,2, LIU Yang1,2, LI Hao1,2,3, LIAO Xiaoling4, CHENG Si1,2,3)

“…Methods A modular analysis system was constructed based on international GWAS quality control standards and multi-omics integration strategies. Pre-GWAS data quality control module: this module performed stringent quality control on sample and variant call rates, population genetic structure and stratification, and kinship. …”
Get full text

Can Different Cultivars of <i>Panicum maximum</i> Be Identified Using a VIS/NIR Sensor and Machine Learning? by Gelson dos Santos Difante, Gabriela Oliveira de Aquino Monteiro, Juliana Caroline Santos Santana, Néstor Eduardo Villamizar Frontado, Jéssica Gomes Rodrigues, Aryadne Rhoana Dias Chaves, Dthenifer Cordeiro Santana, Izabela Cristina de Oliveira, Luis Carlos Vinhas Ítavo, Fabio Henrique Rojo Baio, Gabriela Souza Oliveira, Carlos Antonio da Silva Junior, Vanessa Zirondi Longhini, Alexandre Menezes Dias, Paulo Eduardo Teodoro, Larissa Pereira Ribeiro Teodoro

“…<i>Panicum maximum</i> cultivars have distinct characteristics, especially morphological ones related to the leaf structure and coloration, and there may be differences in the spectral behavior captured by sensors. …”
Get full text

Clarin‐2 is essential for hearing by maintaining stereocilia integrity and function by Lucy A Dunbar, Pranav Patni, Carlos Aguilar, Philomena Mburu, Laura Corns, Helena RR Wells, Sedigheh Delmaghani, Andrew Parker, Stuart Johnson, Debbie Williams, Christopher T Esapa, Michelle M Simon, Lauren Chessum, Sherylanne Newton, Joanne Dorning, Prashanthini Jeyarajan, Susan Morse, Andrea Lelli, Gemma F Codner, Thibault Peineau, Suhasini R Gopal, Kumar N Alagramam, Ronna Hertzano, Didier Dulon, Sara Wells, Frances M Williams, Christine Petit, Sally J Dawson, Steve DM Brown, Walter Marcotti, Aziz El‐Amraoui, Michael R Bowl

“…Our knowledge of the mechanisms underlying the formation and maintenance of the sound‐receptive structure is limited. Utilizing a large‐scale forward genetic screen in mice, genome mapping and gene complementation tests, we identified Clrn2 as a new deafness gene. …”
Get full text

The accumulation characteristics and exploration potential of oil and gas in the back-arc basin of Japan under the background of high heat flow by Jian-qiang Wang, Jie Liang, Jian-wen Chen, Qing-fang Zhao, Yin-guo Zhang, Jian-wei Zhang, Sen Li, Chang-qing Yang, Jian Zhang, Jing Sun, Chuan-sheng Yang, Yong Yuan, Lee-Jel Jiang

“…The trap types are mainly structural traps, lithologic traps and composite traps. …”
Get full text

Tagging large CNV blocks in wheat boosts digitalization of germplasm resources by ultra-low-coverage sequencing by Jianxia Niu, Wenxi Wang, Zihao Wang, Zhe Chen, Xiaoyu Zhang, Zhen Qin, Lingfeng Miao, Zhengzhao Yang, Chaojie Xie, Mingming Xin, Huiru Peng, Yingyin Yao, Jie Liu, Zhongfu Ni, Qixin Sun, Weilong Guo

“…Abstract Background The massive structural variations and frequent introgression highly contribute to the genetic diversity of wheat, while the huge and complex genome of polyploid wheat hinders efficient genotyping of abundant varieties towards accurate identification, management, and exploitation of germplasm resources. …”
Get full text

Prognostic impact of small size sutureless prostheses: results for 241 patients from an international registry by Giuseppe Santarpino, Roberto Lorusso, Giovanni Concistrè, Josè Cuenca Castillo, Vincenzo Argano, Alistair Royse, Angelo Lucas Nobre, Patrick Parrino, Gianluigi Bisleri, Max Baghai, Theodor Fischlein, Giovanni Troise, Generoso Mastrogiovanni, Raphael Fontaine, Davide Pacini, Giuseppe Minniti, Aniello Pappalardo, George Chad Hughes, Philippe Noirhomme, Jean-Philippe Grimaud, Maximilian Scherner, Ignacio Muñoz, George Asimakopoulos, Antony Walker, Daniela Zakova, Michele Torella, Giorgio Vigano, Mark Connolly, Christian Dinges, Pierre Corbi, Loris Salvador, Mauro Rinaldi, Luis Maroto, David Heimansohn, Basel Ramlawi, Mattia Glauber, Jlenia D’Agnano, Valeria Cosco, Veronica D’Anna, Marco Solinas

“…At a maximum follow-up of 8.1 years, 10 cardiovascular deaths, 4 valve related reinterventions (3 structural valve deterioration (SVD) requiring TAVI Valve-in-Valve, 1 endocarditis) occurred. …”
Get full text

Exploring perceptions and preferences for PrEP choice and of an mHealth intervention: insights from the ImPrEP CAB‐Brasil study by Cristina Pimenta, Claudio G. Mann, Brenda Hoagland, Eduardo Carvalheira, Cristina Jalil, Marcos Benedetti, Nilo Fernandes, Carolina Coutinho, Emilia M. Jalil, Mayara Secco Torres Silva, Roberta Trefiglio, Alessandro Farias, Maria Paula G. Mourão, José Valdez Madruga, Josué N. deLima, Ronaldo Zonta, Gabrielle O'Malley, Valdilea G. Veloso, Beatriz Grinsztejn, Thiago S. Torres, for the ImPrEP CAB‐Brasil Study

“…A subset of participants from each site were invited to participate in the qualitative study (October 2023−July 2024). Semi‐structured interviews were conducted, recorded and transcribed. …”
Get full text

Beneficial effects of Lactobacillus plantarum on growth performance, immune status, antioxidant function and intestinal microbiota in broilers by Xiao Xiao, Tiantian Cui, Songke Qin, Tao Wang, Jinsong Liu, Lihan Sa, Yanping Wu, Yifan Zhong, Caimei Yang

Get full text

Deep learning-based carotid plaque vulnerability classification with multicentre contrast-enhanced ultrasound video: a comparative diagnostic study by Yanli Guo, Hongxia Zhang, Yang Guang, Wen He, Bin Ning, Chen Yin, Mingchang Zhao, Fang Nie, Pintong Huang, Rui-Fang Zhang, Qiang Yong, Jianjun Yuan, Yicheng Wang, Lijun Yuan, Litao Ruan, Tengfei Yu, Haiman Song, Yukang Zhang

“…Moreover, with a more powerful network structure and better utilisation of video information, DL-DCCP provided greater diagnostic accuracy than a state-of-the-art static CNN model.Trial registration number ChiCTR1900021846,…”
Get full text

A Multifaceted Computational Approach to Identify PAD4 Inhibitors for the Treatment of Rheumatoid Arthritis (RA) by Mansour S. Alturki, Mohamed S. Gomaa, Nada Tawfeeq, Abdulaziz H. Al Khzem, Mohsina B. Shaik, Murtadha Alshaikh Jafar, Mohammad Alsamen, Hasan Al Nahab, Mohammad Al-Eid, Alhassan Almutawah, Thankhoe A. Rants’o, Khaled A. G. Ayil, Mohammed Almaghrabi

“…Methods: We utilized Maestro Schrödinger as a computational tool for preparing and docking simulations on the PAD 4 enzyme crystal structure that is retrieved from RCSB Protein Data Bank (PDB ID: 4X8G) while the docked FDA-approved medications are obtained from the Zinc 15 database. …”
Get full text