Isolation, Identification, and Molecular Genetic Characteristics of a Pathogenic Strain of <i>Streptococcus suis</i> Serotype 3 by Longbai Wang, Jingli Qiu, Bing He, Xuemin Wu, Qiuyong Chen, Quanxi Wang, Renjie Wu, Bohan Zheng, Lunjiang Zhou, Xiaohong Huang

“…Different <i>S. suis</i> serotypes exhibit diverse characteristics in population structure and pathogenicity. Epidemiology data underscore the importance of <i>S. suis</i> serotype 3 (SS3). …”
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School nutrition programs in Dubai: a landscape analysis by Reem AlGurg, Reem AlGurg, Nour Abu Mahfouz, Farah Otaki, Farah Otaki, Agnes Paulus, Agnes Paulus, Amar Hassan Khamis, Mohamad Alameddine

“…The stakeholders involved in developing and maintaining the respective SNPs and the intended outcomes of those programs also differed across the schools.ConclusionThis study highlights, in alignment with Sustainable Development Goals 3, 4, 9 and 17, the importance of the proposed reformation around SNPs in Dubai to take into account the governance structure on the local and national levels, quality assurance measures, stakeholder engagement, and programs’ intended outcomes and compositions. …”
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Gut microbiota characteristics in neonatal respiratory distress syndrome and the therapeutic potential of probiotics in recovery by Yongcheng Fu, Xiujuan Wang, Lintao Nie, Zhaorui Wang, Xiao Ma, Lijia Wu, Liping Han, Wenjun Fu, Ruoming Wang, Hongyan Ren, Da Zhang, Juan Ding

“…Probiotic intervention notably restored the gut microbiota structure in the NRDS group, particularly by enhancing the abundance of beneficial genera such as Streptococcus, Bifidobacterium, and Clostridium. …”
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Effects of perinatal variables on echocardiographic assessments of left ventricular dimensions in infants born large for gestational age: a prospective cohort analysis by Ahmed Amarah, Ibrahim Elmakaty, Iram Nadroo, Manoj Chhabra, Danthanh Hoang, Debbie Suk, Ali M. Nadroo, Nitin Ron, Beata Dygulska, Madhu B. Gudavalli, Pramod Narula, Ashraf Gad

“…Certain perinatal variables were identified as key determinants affecting various aspects of LV structure. These insights highlight the importance of considering these perinatal factors in neonatal cardiac assessments for early detection and intervention.…”
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التكاليف والخسائر الاقتصادية للحوادث المرورية لمدينة البصرة للسنوات (2004-2009) by وائل قاسم راشد

“…In order to address and address this risk, the research structure included a number of topics dealing with the types of traffic accidents and their causes, methods of calculating the economic costs resulting from them and their effects on the macroeconomic variables. …”
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Educide amid conflict: the struggle of the Palestinian education system by Dalal Iriqat, Rula Alousi, Tahani Z. Aldahdouh, Alaa AlDahdouh, Iman Dankar, Dima Alburai, Mohamed Buheji, Abdo Hassoun

“…Evidence indicates that such deliberate targeting aims to destabilize Gaza’s social structure and hinder long-term development. The findings highlight the urgent need for international accountability to halt these acts, safeguard education as a fundamental right and rebuild Gaza’s education system to ensure resilience and continuity amid conflict. …”
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Emotional literacy programme in special schools for children with a learning disability in England: the ZF-SEND feasibility RCT by Biza Stenfert Kroese, Gemma Unwin, Richard Hastings, Andrew Jahoda, Rachel McNamara, David Gillespie, Jeremy Segrott, Kate Ingarfield, Myrsini Gianatsi, Elizabeth Randell, Zoe Mather, Barbara Barrett, Poushali Ganguli, John Rose, Mariam Sahle, Emily Warren, Nathan Da Cruz

“…The key aims were to assess the acceptability and feasibility of participating in the trial, data collection and the Zippy’s Friends special educational needs and disabilities intervention through quantitative and qualitative data collection. …”
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Using a “Kickoff” to build implementation partner teams and action plans for active implementation of a quality improvement project by Sean A. Baird, Sean A. Baird, Teresa M. Damush, Teresa M. Damush, Teresa M. Damush, Teresa M. Damush, Nicholas A. Rattray, Nicholas A. Rattray, Nicholas A. Rattray, Nicholas A. Rattray, Lauren S. Penney, Lauren S. Penney, Lauren S. Penney, Edward J. Miech, Edward J. Miech, Edward J. Miech, Edward J. Miech, Barbara J. Homoya, Jared Ferguson, Laura J. Myers, Laura J. Myers, Laura J. Myers, Laura J. Myers, Dawn M. Bravata, Dawn M. Bravata, Dawn M. Bravata, Dawn M. Bravata, Dawn M. Bravata

“…The PREVENT kickoff was designed from multiple frameworks: theory of change principles for process improvement; Consolidated Framework for Implementation Research (CFIR); social learning models; and systems redesign. Data collected included pre-kickoff planning documents and post-kickoff debriefs from the PREVENT national team, Audience Response System (ARS) data, post-kickoff site participant evaluations and semi-structured interviews.ResultsSite team participants reflected positively on the framework driven, interactive and interpersonal design elements, team building, and action plan exercises, and found them useful for a successful project launch. …”
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Exploring ultrasound and electromyography for carpal tunnel syndrome diagnosis: a comprehensive comparative study and implications for occupational medicine by Salem Braham, Salem Braham, Amen Moussa, Amen Moussa, Marwa Bouhoula, Marwa Bouhoula, Nihel Ben Meriem, Nihel Ben Meriem, Ichraf Annen, Ichraf Annen, Ghazi Sakly, Ghazi Sakly, Asma Chouchane, Asma Chouchane, Malek Ben Abdelkader, Malek Ben Abdelkader, Asma Aloui, Asma Aloui, Imène Kacem, Imène Kacem, Maher Maoua, Maher Maoua, Houda Kalboussi, Houda Kalboussi, Olfa Elmaalel, Olfa Elmaalel, Houda Mhabrech, Houda Mhabrech, Souheil Chatti, Souheil Chatti, Aicha Brahem, Aicha Brahem

“…BackgroundTo assess the contribution of ultrasound in diagnosing occupational carpal tunnel syndrome (CTS), compare it with electromyography (EMG) results, and evaluate the ultrasound characteristics of CTS patients.MethodsA nine-month cross-sectional study (January–September 2021) involved CTS patients and a control group, utilizing a structured form for data collection. EMG was performed on the patient group (‘cases’) and ultrasound examinations were conducted on both groups. …”
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Costs of biomarker testing in advanced non‐small cell lung cancer: a global study comparing next‐generation sequencing and single‐gene testing by Umberto Malapelle, Chien‐Chin Chen, Enrique deÁlava, Paul Hofman, Daniel Kazdal, Tae‐Jung Kim, Tony Kiat Hon Lim, Aleš Ryška, Angelica A Saetta, Ed Schuuring, Giancarlo Troncone, Michele Biscuola, Yi‐Lin Chen, Gek San Tan, Charles Hugo Marquette, Maria Michelli, Arja terElst, Hana Vošmiková, Joshua Kapp, Sebastian Gonzalez‐McQuire, Andromachi Giannopoulou, Jean Marie Franzini, Victoria Lucia Rabsiun Aramburu, Anna Baggi, Albrecht Stenzinger

“…This observational study was conducted across 10 pathology centers in 10 different countries worldwide. Biomarker data collected via structured questionnaires (1 January–31 December 2021) were used to feed micro‐costing analyses for three scenarios [‘Starting Point’ (SP; 2021–2022), ‘Current Practice’ (CP; 2023–2024), and ‘Future Horizons’ (FH; 2025–2028)] in both a real‐world model, comprising all biomarkers tested by each center, and a standardized model, comprising the same sets of biomarkers across centers. …”
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Mitigating Polarization Leakage in Gas Pixel Detectors through Hybrid Machine Learning and Analytic Event Reconstruction by Nicoló Cibrario, Michela Negro, Raffaella Bonino, Nikita Moriakov, Luca Baldini, Niccoló Di Lalla, Alessandro Di Marco, Sergio Fabiani, Andrea Frassá, Alessio Gorgi, Fabio La Monaca, Luca Latronico, Simone Maldera, Alberto Manfreda, Fabio Muleri, Nicola Omodei, John Rankin, Carmelo Sgró, Stefano Silvestri, Paolo Soffitta, Stefano Tugliani

“…This work presents the first application of this hybrid method to experimental data, including both calibration lab measurements and IXPE observational data. …”
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Clinical genome sequencing in patients with hereditary breast and ovarian cancer: Concept, implementation and benefits by Dennis Witt, Marc Sturm, Antje Stäbler, Benita Menden, Lisa Ruisinger, Kristin Bosse, Ines Gruber, Andreas Hartkopf, Silja Gauß, German Demidov, Nicolas Casadei, Elena Buena Atienza, Kira Mehnert, Janna Witt, Caspar Gross, Leon Schütz, Christopher Schroeder, Stephan Ossowski, Andreas Dufke, Tobias B. Haack, Olaf Riess, Ulrike Faust

“…GS offers a wealth of information, including the improved detection of structural variants, copy number variants, and parallel detection of complex genetic markers. …”
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Optical genome mapping: Unraveling complex variations and enabling precise diagnosis in dystrophinopathy by Jiahui Mai, Jing Duan, Xiaoyu Chen, Liqin Liu, Dachao Liang, Tao Fu, Gang Lu, Wai Yee Chan, Xufeng Luo, Feiqiu Wen, Jianxiang Liao, Zhuo Li, Xinguo Lu

“…We used the optical genome mapping (OGM) technology to detect and analyze uncommon mutations or structural variations (SVs) within the DMD gene, thus contributing to more precise clinical diagnoses. …”
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CTV-MIND: A cortical thickness-volume integrated individualized morphological network model to explore disease progression in temporal lobe epilepsy by Xinyan Liu, Jiaqi Han, Xiating Zhang, Boxuan Wei, Lu Xu, Qilin Zhou, Yuping Wang, Yicong Lin, Jicong Zhang

“…This study aimed to investigate progressive changes in TLE by constructing a novel individualized morphological brain network based on T1-weighted structural magnetic resonance imaging (MRI). MRI data were collected from 34 postoperative seizure-free TLE patients and 28 age- and sex-matched healthy controls (HC), with patients divided into LONG-TERM and SHORT-TERM groups. …”
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Safety of mycophenolate mofetil in systemic lupus erythematosus maintenance therapy: insights from the LUNA registry in a nationwide prospective cohort study by Ken-ei Sada, Shuhei Yoshida, Kenji Saito, Yuya Fujita, Eisuke Inoue, Kiyoshi Migita, Naoki Matsuoka, Hiroshi Kajiyama, Ryusuke Yoshimi, Kunihiro Ichinose, Yoshia Miyawaki, Shigeru Ohno, Nobuyuki Yajima, Yasuhiro Shimojima, Shuzo Sato, Michio Fujiwara, Keisuke Nishimura, Takashi Kida, Yuya Sumichika, Haruki Matsumoto, Jumpei Temmoku, Tomoyuki Asano, Shotaro Ogawa, Jumpei Fukita, Yusuke Matsuo, Takahisa Onishi

“…Statistical analyses employed marginal structural models with stabilised inverse probability of treatment weighting to adjust for confounders.Results The analysis included 1004 patients; the incidence of severe infections was 6.5% in the MMF group and 7.5% in the non-MMF group, with no significant difference (OR 0.69, 95% CI 0.34 to 1.39). …”
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The mediating role of physical activity avoidance in the association between weight stigma and physical activity by Po-Ching Huang, Hung-Ching Wu, Ji-Kang Chen, Xavier C.C. Fung, Nadia Bevan, Daniel Kwasi Ahorsu, Mark D. Griffiths, Jung-Sheng Chen, Kuo-Hsin Lee, Amir H. Pakpour, Chung-Ying Lin

“…Results: Structural equation modeling showed that weight-related self-stigma was significantly associated with PA avoidance (standardized coefficient [β] = 0.67, p < 0.01), and negatively associated with PA (β = −0.14, p < 0.01). …”
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Executive dysfunction relates to salience network desegregation in behavioural variant frontotemporal dementia by Melanie A. Matyi, Hamsanandini Radhakrishnan, Christopher A. Olm, Jeffrey S. Phillips, Philip A. Cook, Emma Rhodes, James C. Gee, David J. Irwin, Corey T. McMillan, Lauren Massimo

“…Given that behavioral variant frontotemporal degeneration (bvFTD) is a neurodegenerative disease associated with executive dysfunction and selective vulnerability of the salience network, we tested the hypotheses that bvFTD structural networks are de-differentiated compared to cognitively normal controls (CNC) and that network de-differentiation relates to worse executive function. …”
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Single-cell chromatin accessibility profiling reveals regulatory mechanisms and evolution in pig brains by Yue Xiang, Saixian Zhang, Yi Huang, Zhuqing Zheng, Jiahui Sun, Qiulin Zhao, Peng Zhou, Xiaolong Qi, Jingjin Li, Fuyang Xiong, Jing Xu, Shengquan Wang, Liangliang Fu, Xinyun Li

“…Abstract Background Pig brains serve as a valuable biomedical model for studying brain-related diseases due to their significant structural similarities to the human brain. Furthermore, the long-term domestication and artificial selection of domestic pigs have profoundly shaped their brains, making them an interesting subject for research. …”
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MSAN-Net: An End-to-End Multi-Scale Attention Network for Universal Industrial Defect Detection by Zelu Wang, Ming Luo, Xinghe Xie, Yue Sun, Xinyu Tian, Zhengxuan Chen, Junwei Xie, Qinquan Gao, Tong Tong, Yue Liu, Tao Tan

“…MSAN-Net was adopted an integrated architecture, deeply combining UnifiedViT, C2f modules, convolution operations, SPPF structure, and Bi-Level Routing Attention mechanism to achieve accurate identification of complex industrial defects. …”
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Inhibition Mechanism of Pleurotus citrinipileatus Sing. Ergothioneine on Pancreatic Lipase Activity by Zhangchen XIA, Xiaohui MENG, Ru FANG, Yanqing MAO, Junwen CHENG, Yanbin WANG, Juan XU, Liang HE

“…The UV spectrum indicated there was a π→π* transition produced by the peptide bond C=O group of PL as the mass concentration of PCEGT increased, which could reflect the reinforcement of polarity and hydrophilicity. Fluorescence spectra data revealed PCEGT could efficiently static-quench the intrinsic fluorescence of PL by changing its space structure. …”
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