Examining the evolution and impact of OTC vending machines in Global Healthcare Systems by Ammar Abdulrahman Jairoun, Sabaa Saleh Al-Hemyari, Moyad Shahwan, Sahab Alkhoujah, Faris El-Dahiyat, Ammar Ali Saleh Jaber, Sa'ed H. Zyoud

“…Conclusions: This study emphasises the practical necessity for enhanced regulatory structures to mitigate risks such as medication abuse, unfavourable drug interactions, and incorrect dispensing practices. …”
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Phytochemical Study and In Vitro Antioxidant Activity of <i>Helianthemum cinereum</i> Along with Antitumor Activity of the Isolated <i>trans</i>-Tiliroside and Luteolin 4′-<i>O</i>... by Anis Bertella, Abla Smadi, Hakim Benhabrou, Diana Salvador, Magdalena Wrona, Helena Oliveira, Abouamama Sidaoui, Georgiana Gavril-Luminita, Diana C. G. A. Pinto, Ewa Olewnik-Kruszkowska, Cristina Nerín, Artur M. S. Silva, Fatma Bitam

“…All compounds were isolated by applying different chromatographic procedures, such as silica gel, RP-18 and Sephadex LH-20 columns. The structures were elucidated by extensive spectroscopic methods, mainly nuclear magnetic resonance NMR 1D and 2D, and mass spectrometry, as well as by comparison with the reported spectroscopic data. …”
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Presenting the model of social entrepreneurship in the development of rural tourism in the target villages of Gilan province by Fatemeh Doozandeh Ziabari, hamed fallah tafti, Mir Mohammad Asadi, Mahdi Basouli

“…On the other hand, in order for tourism destinations to be able to create a competitive advantage, businesses related to local tourism should follow the model of social businesses that use innovative strategies related to the provision of products and services, organizational structure, operational processes, procurement and marketing.…”
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PATHOGENESIS-RELATED PROTEINS: identification, evolution and functional analysis in pear (Pyrus bretschneideri) by Chenyang Han, Qi Wang, Zhiyuan Su, Chaohui Li, Baodian Guo, Fanhang Zhang, Bao Tang, Yancun Zhao, Fengquan Liu, Shaoling Zhang

“…Phylogenetic, sequence similarity, and secondary structure analyses enabled the classification of several PRs with conserved sequences, including PR-11, PR-8, PR-15, and PR-16. …”
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A Multiscale Fractal Approach for Determining Cushioning Curves of Low-Density Polymer Foams by Mariela C. Bravo-Sánchez, Luis M. Palacios-Pineda, José L. Gómez-Color, Oscar Martínez-Romero, Imperio A. Perales-Martínez, Daniel Olvera-Trejo, Jorge A. Estrada-Díaz, Alex Elías-Zúñiga

“…A two-scale transform is employed to solve the mathematical model and predict the material’s behavior under impact loads, accounting for the fractal structure of the material’s molecular configuration. …”
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Selective hydrogenation of 5-hydroxymethylfurfural triggered bya high Lewis acidic Ni-based transition metal carbide catalyst by Rulu Huang, Jianchun Jiang, Jie Liang, Shanyong Wang, Yuwei Chen, Xianhai Zeng, Kui Wang

“…The high-efficiency conversion of biomass resources to biofuels has attracted widespread attention, and the active sites and synergistic effect of catalysts significantly impact their surface arrangement and electronic structure. Here, a nickel-based transition metal carbide catalyst (Ni/TMC) with high Lewis acidity was prepared by self-assembly of transition metal carbide (TMC) and nickel, which exhibited excellent performance on synergistic hydrogenation and hydrogenolysis of 5-hydroxymethylfurfural (HMF) into liquid biofuel 2,5-dimethylfuran (DMF). …”
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Using Quantitative Trait Locus Mapping and Genomic Resources to Improve Breeding Precision in Peaches: Current Insights and Future Prospects by Umar Hayat, Cao Ke, Lirong Wang, Gengrui Zhu, Weichao Fang, Xinwei Wang, Changwen Chen, Yong Li, Jinlong Wu

“…This study examines the complex genetic structure that underlies the morphology of peach fruits, paying special attention to the interaction between genome editing, genomic selection, and marker-assisted selection. …”
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The Cuitzeo granitic xenolith: evidence of an Early Miocene magma plumbing system in central Mexico by María del Sol Hernández-Bernal, Pedro Corona-Chávez, Noemí Trujillo-Hernández, Consuelo Macías-Romo, Dante Jaime Morán-Zenteno, Adrián Jiménez-Haro, Stefano Poli

“… Relevant data on the structure and composition of the crystalline basement in Central México can be found by means of plutonic, metamorphic, and sedimentary xenoliths transported by Neogene and Quaternary volcanic eruptions within the Trans-Mexican Volcanic Belt (TMVB). …”
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Evaluating the Predictive Accuracy of an AI-Based Tool for Postoperative Vault Estimation in Phakic Intraocular Lens Implantation by Zaldivar R, Zaldivar R, Cummings AB, Cummings BK, Mertens EL, Ang RE, Zarate Piscopo LI, Quintero G, Cerviño A

“…The AI tool used high-resolution ultrasound images and biometric data (measurements of the eye) to predict the vault. …”
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Changes in auditory cortex subregions and their prediction for sound therapy outcomes in patients with tinnitus by Ling Wang, Yu Zhang, Rui Zhao, Yan Huang, Xinghao Wang, Yuyou Huang, Jiancheng Zhang, Han Lv, Pengfei Zhao, Zhenghan Yang, Qian Chen, Zhenchang Wang

“…Objective: To examine structural and functional changes in auditory cortex(AC) subregions of patients with tinnitus and identify potential predictive indicators for sound therapy. …”
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Influencing Factors and Paths of the Coupling Relationship Between Ecosystem Services Supply–Demand and Human Well-Being in the Hexi Regions, Northwest China by Yongge Li, Wei Liu, Meng Zhu, Qi Feng, Linshan Yang, Jutao Zhang, Zhenliang Yin, Xinwei Yin

“…Here, we assessed dynamic changes in ecosystem services supply–demand, human well-being, their coupling relationships and influencing factors in the Hexi Regions by integrating remote sensing data, ecological model, ecosystem services supply–demand ratio (ESDR), coupling coordination degree (CCD) model, and the partial least squares structural equation modeling (PLS-SEM). …”
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Ecotype-specific responses of Typha domingensis to microplastics: Antioxidant defense and biochemical adaptations in wetland ecosystems by Muhammad Aqeel, Ali Noman, Saher Nawaz, Noreen Khalid, Muhammad Kashif Irshad, Muhammad Faisal Iqbal, Modhi O. Alotaibi, Motirh Al-Mutairi, Mohamed O. Alshahrani, Nahaa M. Alotaibi, Fahad Mohammed Alzuaibr

“…The inherent ability of plants to withstand microplastic (MP) stress is primarily governed by complex structural and physio-biochemical adaptations. In this study, the MP tolerance mechanisms of six naturally occurring ecotypes of Typha domingensis Pers. were assessed by examining plant pigments, ionic homeostasis, secondary metabolites, and antioxidant defense responses in MP-contaminated wetlands. …”
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Synthesis of Mg-, Al- and Mg/Al-date palm fronds modified biochars: characterization and investigations on phosphorus adsorption characteristics by Jellali, Salah, Hadroug, Samar, Al-Wardy, Malik, Hamdi, Helmi,  Al-Sabahi, Jamal, Bekri, Imene, Al-Raeesi, Ahmed, Hamdi, Wissem,  Jeguirim, Mejdi

“…In this study, three biochars were synthesized at 500 °C from pre-impregnated date palm fronds (DPFs) with 1 M solutions containing either MgCl2 (DPF-Mg-B), AlCl3 (DPF-Al-B) or a combination of MgCl2/AlCl3 (DPF-Mg/Al-B). Subsequently, the structural, textural, and surface chemistry properties of these biochars were assessed. …”
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snRNA-seq reveals subcutaneous white adipose tissue remodeling upon return to thermoneutrality after cold stimulation by Yusha Yang, Yusha Yang, Guanyu Zhang, Ting Yi, Ting Yi, Shuran Yang, Shuran Yang, Shuai Wu, Yongqiang Zhang, Li Zhang, Xi Li, Xiuxuan Wu, Xiuxuan Wu, Jun Li, Danfeng Yang

“…Subsequently, we employed single-nucleus RNA sequencing (snRNA-seq) to comprehensively characterize iWAT cellular dynamics during cold stimulation and the subsequent two-week period after the return to thermoneutrality.ResultsOur findings revealed that while iWAT phenotypically reverts to a white state after 2 weeks of rewarming, as evidenced by structural, functional, and bulk transcriptomic characteristics, significant cold-induced molecular and cellular signatures persist. …”
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Mediation of nutritional status between the number of teeth and depressive symptoms in multi-ethnic older adults from Western China by Xin Tian, Xin Xia, Huixian Li, Yuexia Hu, Yuqing Xie, Xiuying Hu, Jirong Yue, Birong Dong, Bei Wu, Yanyan Wang

“…Mediation analysis confirmed nutritional status partially mediated the relationship between the number of teeth and depressive symptoms (indirect effect estimate = −0.059; 95% CI −0.076, −0.044, direct effect estimate = −0.089; 95% CI −0.158, −0.020). Furthermore, structural equation model for pathway analysis verified the correlation between the number of teeth, nutritional status, and depressive symptoms (p &lt; 0.05).ConclusionNutritional status partially mediated the association between the number of teeth and depressive symptoms, revealing significant direct and indirect effects. …”
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The PA-X host shutoff site 100 V exerts a contrary effect on viral fitness of the highly pathogenic H7N9 influenza A virus in mice and chickens by Xia Chen, Ming Kong, Chunxi Ma, Manyu Zhang, Zenglei Hu, Min Gu, Xiaoquan Wang, Ruyi Gao, Shunlin Hu, Yu Chen, Xiaowen Liu, Daxin Peng, Xiufan Liu, Jiao Hu

“…By analysing the polymorphism of this residue in various subtype viruses, we found that PA-X 100 was highly variable in H7N9 viruses. Structural analysis revealed that 100 V was generally close to the PA-X endonuclease active site, which may account for its host shutoff activity. …”
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Outdoor Air Pollution Is Related to Amygdala Subregion Volume and Apportionment in Early Adolescence by Jessica Morrel, L. Nate Overholtzer, Kirthana Sukumaran, Devyn L. Cotter, Carlos Cardenas-Iniguez, J. Michael Tyszka, Joel Schwartz, Daniel A. Hackman, Jiu-Chiuan Chen, Megan M. Herting

“…Background: Outdoor air pollution exposure is associated with structural and functional brain differences and an increased risk for psychopathology. …”
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Re-use of Building Products in the Netherlands by Loriane Icibaci

“…The proposed conceptual model evolved from a composition of concepts adapted from the Industrial Ecology theoretical background to represent the system of the typical commercial practice of reuse of building products in the Netherlands, supplied by-products derived from the housing stock, and are centralized on the role of the practitioner. Accordingly, the data collection and most findings from the qualitative analysis departed from clustering information structured by the preconceived theoretical framework. …”
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Faster efficacy and reduced nodule occurrence with PLLA (poly-l-lactic acid) porous microspheres by Qihua Cao, Qihua Cao, Qihua Cao, Jiayu Chen, Jiayu Chen, Jiayu Chen, Jiayu Chen, Zijun Zhang, Yufei Xiong, Jinxia Ma, Wei Sun, Xin Chen, Qilei Lou, Kaijia Tang, Kaijia Tang, Kaijia Tang, Kaijia Tang, Feng Lin, Feng Lin, Feng Lin, Yueliang Zhu, Yueliang Zhu, Yueliang Zhu, Xiaohua Yu, Xiaohua Yu, Xiaohua Yu, Xiaohua Yu

“…Post-euthanasia, tissue sections underwent histological examination through hematoxylin and eosin (H&amp;E) staining and Masson’s trichrome technique, with subsequent statistical analysis of the observational data.ResultsThe PLLA porous microsphere group demonstrated significantly faster onset of action compared to the control, with observable collagen deposition as early as week 2, enhanced inflammatory cell infiltration, more homogeneous tissue distribution, and substantially fewer microaggregates upon histological examination.DiscussionStructural modification of PLLA microspheres has successfully accelerated their onset of action while reducing nodule formation, thereby providing novel insights for clinical applications.…”
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An open-source simulation platform to support and foster research collaboration in natural hazards engineering by Adam Zsarnóczay, Gregory G. Deierlein, Frank McKenna, Matthew Schoettler, Sang-Ri Yi, Barbaros Cetiner, Aakash Bangalore Satish, Jinyan Zhao, Justin Bonus, Abiy F. Melaku, Sina Naeimi, Pedro Arduino, Rachel Davidson, Rachel Davidson, Catherine Gorle, Sanjay Govindjee, Ahsan Kareem, Tracy L. Kijewski-Correa, Tracy L. Kijewski-Correa, Laura N. Lowes, Michael Motley, Seymour M. J. Spence, Ertugrul Taciroglu, Alexandros A. Taflanidis, Matthew DeJong

“…This paper presents the conceptual foundation and current capabilities of the SimCenter platform, covering hazard characterization, structural response analysis, damage and loss estimation, and recovery modeling. …”
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