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50481
Cancer-associated VEGFR2R1032Q sustains receptor activation also by promoting ligand-independent hetero-dimerization with co-expressed wild-type VEGFR2 and translocation into lipid...
Published 2025-09-01“…This was associated with reduced mobility of the receptor on the membrane, linked to its translocation into detergent-resistant membrane (DRM) domains (e.g. lipid rafts), which showed alterations in lipid compositions and structure. These data shed light on a novel oncogenic mechanism of activation of VEGFR2, clarifying the paradoxical loss-of-function nature of the substitution R1032Q of VEGFR2.…”
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50482
Main factors of primary arterial hypertension development and pathogenesis in young, call-up-aged men with complicated family anamnesis
Published 2007-06-01“…Hemodynamics was assessed by blood pressure (BP) office measurement and ambulatory monitoring, together with B-mode echocardiography data. Renal and renourinal structure and function was assessed by static and dynamic scintigraphy, renal ultrasound, renal radiography, excretory urography, color Doppler angiography of renal arteries, measurement of microalbuminuria in morning urine and glomerular filtration rate by endogenous creatinine. …”
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50483
Long-term Astrometric Monitoring of the Galactic Center Magnetar PSR J1745−2900
Published 2025-01-01“…We consider several potential sources of systematic variations in the astrometric residuals after fitting for standard parameters, including refractive wander, changes in the structure of Sgr A*, and the presence of an unseen binary companion. …”
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50484
ROSA: An Andean Network of Social–Ecological Observatories
Published 2024-11-01“…We describe the origins, structure, objectives, and strategies of ROSA and key challenges faced by different monitoring networks working in the region with regard to data generation and knowledge transfer. …”
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50485
Identifying lifelong factors that impact brain health and functional outcomes in adults with childhood-onset type 1 diabetes: the cognition and longitudinal assessments of risk fac...
Published 2025-06-01“…Introduction Type 1 diabetes (T1D) is associated with changes in brain structure, cognition, mental health, and functional outcomes. …”
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50486
Evaluating the Usability, Technical Performance, and Accuracy of Artificial Intelligence Scribes for Primary Care: Competitive Analysis
Published 2025-07-01“…Common errors included deletion, omission, and SOAP structure errors. Factors such as extraneous conversations and multiple speakers impacted the accuracy of both the transcript and medical note, with some AI scribes producing excellent notes despite minor transcript issues and vice versa. …”
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50487
Ichthyological aspects of implementing biological amelioration of the cooling pond of the Khmelnytskyi NPP
Published 2025-03-01“…Meanwhile, calculations of annual natural mortality for older age groups based on the analysis of the catch structure and catch statistics data gave the value φF=0.01…0.05. …”
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50488
Molecular and Transmission Characteristics of Mycobacterium Tuberculosis Strains Among College Students in Beijing, China
Published 2025-01-01“…The aim of this study is to analyze the genetic diversity and drug resistance of Mycobacterium tuberculosis strains in college students with tuberculosis in Beijing, revealing the lineage structure and transmission patterns specific to this group.Methods: This study used the hospital’s electronic management system to screen for tuberculosis among college students in Changping District, Beijing, from January 2004 to December 2023. …”
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50489
Characteristics of the epidemic process of Lyme borreliosis in the Sverdlovsk district over a 20-year period
Published 2023-05-01“…The main etiological agent of the erythematous form is Borrelia garinii, while the non-erythematous form is Borrelia miyamotoi and B. garinii. In the general structure of morbidity, the number of cases of LB is largely determined by the city inhabitants (92.9%). …”
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50490
Mixed Sedimentation in the Transition Zone Between a Shallow-Water Delta and Tidal Flat and Its Influence on Reservoir Quality: A Case Study of Member B of the Asmari Formation in...
Published 2025-05-01“…When the dolomite content in sandstone exceeds 25%, the pore–throat structure changes significantly. A small amount of sand in dolostone has little effect on the pore and throat. …”
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50491
Effect of short PSG peptide fragments on the cytokine profile in Wistar rats during allogeneic transplantation <i>in vivo</i>
Published 2022-07-01“…Tetrapeptide regions have been identified in the primary structure of several PSGs: YQCE, YECE and YACS, these SLiMs exhibit immunomodulatory activity. …”
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50492
Modern Approaches to the Development of Head and Respiratory Protective Devices for Military Men
Published 2024-11-01“…The authors also analyzed technical specifications and user manuals for such devices and available academic sources that contain information on their structure and functioning.Discussion. A modern combat uniform set is a combined set that consists of weapon system, management system, protection system life maintenance system and power supply system that are meant to help military men to perform their battle missions both on their own and as a part of a squad, platoon, etc. …”
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50493
Development and evaluation of customized software to automatically align macula and optic disc centered scanning laser ophthalmoscope fundus images
Published 2025-04-01“…Thus, the optic disc-fovea angle needs to be determined and routinely taken into account in morphological glaucoma diagnosis and in the assessment of structure-function relationship in optic nerve diseases. …”
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50494
La readmisión de extranjeros en situación irregular entre Estados miembros: consecuencias empírico-jurídicas de la gestión policial de las fronteras internas | The Readmission of I...
Published 2017-12-01“…The place where the border barrier was once was occupied by a car toll constructed with a very particular structure: as a border, with cabins for police men. …”
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50495
3D-Printed Demultiplexer Circuits Using Suspended-in-Air Grating Couplers for Terahertz Communications
Published 2025-01-01“…However, the measured Drop amplitudes (~0.5–0.6) are lower than the theoretical predictions (~0.8) due to ~10% scattering losses per supporting structure. We believe that the suspended-in-air integrated terahertz circuits hold strong potential for developing various linear optic transformers that will play a key role in energy-efficient analog processing of data streams for the upcoming terahertz communications. …”
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50496
THE ROLE OF CHRONIC POLYPOID RHINOSINUSITIS IN OCCURRENCE OF MALIGNANT EPITHELIAL TUMORS OF THE PARANASAL SINUSES AND THE NASAL CAVITY
Published 2015-04-01“…We believe that the data provided prove the key role of the CPR in development of MET of the NC and the PNS.…”
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50497
اختبار العلاقة بين العدالة التنظيمية والاحتراق الوظيفي - (دراسة تطبيقية في المعهد التقني / كوفة
Published 2017-05-01“…In order to test the validity of the hypotheses, the data were collected through the questionnaire and prepared for this purpose. …”
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50498
Рroblem of miscarriage in multiple pregnancies
Published 2013-08-01“…The aim of this research was to study the features of pregnancy process, structure and frequency of obstetric and antenatal complications in women and newborn. …”
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50499
Exploring Imaging Depth: A Pilot Study About 2D vs. 4D Echocardiography for Tricuspid Valve Evaluation
Published 2025-05-01“…Background: The tricuspid valve (TV) is a complex three-dimensional (3D) anatomical structure; however, current guidelines recommend tricuspid annulus (TA) measurements to be performed with two-dimensional (2D) echocardiography. …”
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50500
Decentralized Biobanking Apps for Patient Tracking of Biospecimen Research: Real-World Usability and Feasibility Study
Published 2025-04-01“…Our pilot reveals potential to accelerate biomedical research through patient engagement; however, further development is needed to optimize the accessibility, efficiency, and scalability of platform design and blockchain elements, as well as a robust incentive and governance structure for decentralized biobanking.…”
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