Antiplasmodial activity of pentyloxyamide-based histone deacetylase inhibitors against Plasmodium falciparum parasites by Wisam A. Dawood, Gillian M. Fisher, Josefa Kremeyer, Fabian Fischer, Jessica L. Home, Christopher D. Goodman, Kwong Sum Lam, Alexander G. Maier, Thomas Kurz, Katherine T. Andrews

“…Furthermore, 4o was found to stabilise PfHDAC1 in P. falciparum protein lysates using solvent-induced protein stability Western blot assays with anti-PfHDAC1 antibody. Together, these data provide new structure-activity relationship and mechanistic insights on pentyloxyamide-based HDAC inhibitors as potential therapeutic starting points for malaria.…”
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High-throughput evaluation of half-metallicity of Co2MnSi Heusler alloys using composition-spread films and spin-integrated hard X-ray photoelectron spectroscopy by Ryo Toyama, Shunsuke Tsuda, Yuma Iwasaki, Thang Dinh Phan, Susumu Yamamoto, Hiroyuki Yamane, Koichiro Yaji, Yuya Sakuraba

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Accounting for temporal and spatial autocorrelation to examine the effects of climate change on vegetation greenness trend in China by Lingwei Chen, Likai Zhu, Cuiyutong Yang, Zizhen Dong, Rui Huang, Jijun Meng, Min Liu

“…This method considers temporal and spatial autocorrelation structure, and aggregates pixel information to rigorously test the hypotheses about regional patterns. …”
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Molecular epidemiology of Neisseria gonorrhoeae isolates in Russia, 2015–2023: current trends and forecasting by Ilya Kandinov, Boris Shaskolskiy, Dmitry Kravtsov, Anatoliy Larkin, Alexei Kubanov, Marina Shpilevaya, Julia Shagabieva, Nikita Nosov, Dmitry Gryadunov

“…Two clusters of isolates pose a particular threat to Russia: NG-MAST G2212, linked to MLST 1901/1902, carries a mosaic structure in the penA gene; G12302, linked to MLST 9363, contains mosaic alleles in the mtrR and mtrD genes. …”
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A life cycle thinking-based environmental risk framework for screening sustainable feedstocks in early-stage bioeconomy projects by George Bishop, Carmen Girón-Domínguez, James Gaffey, Maeve Henchion, Réamonn Fealy, Jesko Zimmermann, Wriju Kargupta, David Styles

“…Criteria are proposed to structure evaluation of (i) probability and (ii) severity of environmental impact, in relation to four categories of feedstock: primary (determining product), high-value by-product, low-value by-product, and waste. …”
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Charting the path to the implementation of universal health coverage policy in Nigeria through the lens of Delphi methodology by Jibril M. Bashar, Sulaiman Hadiza, Ozoilo J. Ugochi, Lawal S. Muhammad, Adeoye Olufemi, Ukoh Eberechi, Yakubu Agada-Amade, Alhassan Yusuf, Abdulhamid H. Abdullahi, Hassan S. Musa, Ahmad A. Ibrahim, Kalu-Umeh Nnennaya, Jennifer Anyanti, Dayyabu Yusuf, Kenneth Okoineme, Jennifer Adebambo, Samuel O. Ikani, Dennis Aizobu, Musa Abubakar, Babandi S. Zaharaddeen, Lawal Aminu, Yusuf H. Wada

“…These seven priority areas that have been identified include enrolment, equity, organizational health and structure, data and technology, quality, market efficiency, and citizen engagement. …”
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Genomic investigation of NDM-1 producing Enterobacterales transmission in a South Korean hospital by Jeong-Ih Shin, Sun Hee Park, Chulmin Park, Seung-Hyun Jung, Dong-Gun Lee

“…These plasmids contained conserved mobile genetic elements, including the IS26-dsbD-trpF-ble-blaNDM-1 structure. Conclusions: This study highlights the dual roles of clonal spread and plasmid-mediated horizontal gene transfer in the dissemination of blaNDM-1 in hospital settings. …”
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Sustainable Placemaking and Thermal Comfort Conditions in Urban Spaces: The Case Study of Avenida dos Aliados and Praça da Liberdade (Porto, Portugal) by Hélder Silva Lopes, Paula C. Remoaldo, Diogo Guedes Vidal, Vítor Ribeiro, Lígia Torres Silva, Javier Martín-Vide

“…Furthermore, the study underscored the significance of incorporating adaptive elements, such as greenery, shading structures, and ventilation corridors, into urban design to enhance comfort across different seasons. …”
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Isolation, Identification, and Molecular Genetic Characteristics of a Pathogenic Strain of <i>Streptococcus suis</i> Serotype 3 by Longbai Wang, Jingli Qiu, Bing He, Xuemin Wu, Qiuyong Chen, Quanxi Wang, Renjie Wu, Bohan Zheng, Lunjiang Zhou, Xiaohong Huang

“…Different <i>S. suis</i> serotypes exhibit diverse characteristics in population structure and pathogenicity. Epidemiology data underscore the importance of <i>S. suis</i> serotype 3 (SS3). …”
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School nutrition programs in Dubai: a landscape analysis by Reem AlGurg, Reem AlGurg, Nour Abu Mahfouz, Farah Otaki, Farah Otaki, Agnes Paulus, Agnes Paulus, Amar Hassan Khamis, Mohamad Alameddine

“…The stakeholders involved in developing and maintaining the respective SNPs and the intended outcomes of those programs also differed across the schools.ConclusionThis study highlights, in alignment with Sustainable Development Goals 3, 4, 9 and 17, the importance of the proposed reformation around SNPs in Dubai to take into account the governance structure on the local and national levels, quality assurance measures, stakeholder engagement, and programs’ intended outcomes and compositions. …”
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Gut microbiota characteristics in neonatal respiratory distress syndrome and the therapeutic potential of probiotics in recovery by Yongcheng Fu, Xiujuan Wang, Lintao Nie, Zhaorui Wang, Xiao Ma, Lijia Wu, Liping Han, Wenjun Fu, Ruoming Wang, Hongyan Ren, Da Zhang, Juan Ding

“…Probiotic intervention notably restored the gut microbiota structure in the NRDS group, particularly by enhancing the abundance of beneficial genera such as Streptococcus, Bifidobacterium, and Clostridium. …”
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Effects of perinatal variables on echocardiographic assessments of left ventricular dimensions in infants born large for gestational age: a prospective cohort analysis by Ahmed Amarah, Ibrahim Elmakaty, Iram Nadroo, Manoj Chhabra, Danthanh Hoang, Debbie Suk, Ali M. Nadroo, Nitin Ron, Beata Dygulska, Madhu B. Gudavalli, Pramod Narula, Ashraf Gad

“…Certain perinatal variables were identified as key determinants affecting various aspects of LV structure. These insights highlight the importance of considering these perinatal factors in neonatal cardiac assessments for early detection and intervention.…”
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Achievement of superior strength in Al–Ni dissimilar joints through designing high-entropy alloy interlayer and post weld heat treatment by Byoungwook Choi, Yoona Lee, Seonghoon Yoo, Bong Cheon Park, Junggwan An, Jason Cheon, Dong-Yun Lee, Sung-Dae Kim, Wookjin Lee, Yoon Suk Choi, Namhyun Kang

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A systematic review on environmental DNA (eDNA) Science: An eco-friendly survey method for conservation and restoration of fragile ecosystems by Ashish Sahu, Mahender Singh, Adnan Amin, Monisa Mehboob Malik, Shariq Nazir Qadri, Adnan Abubakr, S.Surya Teja, Shabir Ahmad Dar, Ishtiyaq Ahmad

“…The conservation and restoration of fragile ecosystems and their genetic resources depends on precisely assessing species diversity and richness, understanding spatiotemporal dynamics, and stock structure analysis. Traditional monitoring methods like visual surveys, physical captures, individual counting, sibling or cryptic species identification, and immature life stages (juveniles) of animals are often intrusive, time-consuming, and provide rough estimates. …”
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Monitoring equity in the delivery of health services: a Delphi process to select healthcare equity indicators by Clement P. Buclin, Moreno Doninelli, Laura Bertini, Patrick Bodenmann, Stéphane Cullati, Arnaud Chiolero, Adriana Degiorgi, Armin Gemperli, Olivier Hugli, Anne Jachmann, Yves Jackson, Joachim Marti, Kevin Morisod, Katrina A. Obas, Florian Rüter, Judith Safford, Javier Sanchis-Zozaya, Matthis Schick, Francesca Giuliani, Delphine S. Courvoisier

“…RESULTS: A taskforce of 18 experts, including a patient representative, selected 11 indicators that evaluate structures, processes and outcomes, and five vulnerability stratifiers. …”
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Abundant Molecular Gas in the Central Region of Lenticular Galaxy PGC 39535 by Jiantong Cui, Qiusheng Gu, Shiying Lu, Zhengyi Chen, Can Xu, Zeyu Gao

“…The results of the NOEMA observation suggest that the molecular gas mainly concentrates in the central regions as a gaseous bar and a ring-like structure, and shows similar kinematics as the stellar and ionized gas components. …”
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Modeling the Impacts of Galaxy Intrinsic Alignments on Weak Lensing Peak Statistics by Tianyu Zhang, Xiangkun Liu, Ziwei Li, Chengliang Wei, Guoliang Li, Yu Luo, Xi Kang, Zuhui Fan

“…Weak gravitational lensing (WL) peak statistics capture cosmic nonlinear structures and can provide additional cosmological information complementary to cosmic shear two-point correlation analyses. …”
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Diabetes and periodontitis: the role of a high-glucose microenvironment in periodontal tissue cells and corresponding therapeutic strategies by Dan-dan Xiang, Yu-xin Sun, Chen Jiao, Yu-qian Guo, Yu-xiang Fei, Bai-qiang Ren, Xiao-Tao He, Xuan Li

“…Both of these diseases affect many people worldwide. Epidemiological data have revealed a close relationship between periodontitis and diabetes. …”
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A vegetation strategy to balance the hazardous level of microplastics in the land–sea interface through rhizosphere remediation by Weifeng Ruan, Yanqin Peng, Xi Ling, Bailun Yu, Yiping Tai, Nora Fung-Yee Tam, Yunv Dai, Yang Yang

“…The growth environments and physiological structures of aquatic plants and terrestrial plants differed, resulted in a greater potential for the root systems of aquatic plants to capture MPs. …”
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Evaluation of the oil and gas preservation conditions, source rocks, and hydrocarbon-generating potential of the Qiangtang Basin: New evidence from the scientific drilling project by Li-jun Shen, Jian-yong Zhang, Shao-yun Xiong, Jian Wang, Xiu-gen Fu, Bo Zheng, Zhong-wei Wang

“…Moreover, the Qiangtang Basin has favorable oil and gas preservation conditions, as verified by the comprehensive study of the sealing capacity of seals, basin structure, tectonic uplift, magmatic activity, and groundwater motion. …”
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