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51961
Rare but elevated incidence of hematological malignancy after clozapine use in schizophrenia: A population cohort study.
Published 2024-12-01“…<h4>Methods and findings</h4>We extracted data from a territory-wide public healthcare database from January 2001 to August 2022 in Hong Kong to conduct a retrospective cohort study of anonymized patients aged 18+ years with a diagnosis of schizophrenia who used clozapine or olanzapine (drug comparator with highly similar chemical structure and pharmacological mechanisms) for 90+ days, with at least 2 prior other antipsychotic use records within both groups. …”
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51962
Radiation-hygienic characteristic of the protected zones of peaceful nuclear explosions in the Arkhangelsk region
Published 2021-04-01“…The article presents data on the radiation situation on the territories of the protected zones of peaceful nuclear explosions «Globus-2», «Agat» and «Rubin-1» based on the results of field studies in 2020. …”
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51963
The Effectiveness of Couple Therapy Based on Acceptance and Commitment ACT on Marital Violence and Desire for Separation in Couples Applying for Divorce
Published 2024-10-01“…Methods: The present study applied a quasi-experimental, semi-experimental design with a pre-test and post-test structure, including a control group. The statistical sample consisted of 40 individuals selected from all couples seeking divorce in Yasuj, Iran, who were referred to family counseling centers in the first three months of 2023. …”
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51964
Cloning and Analysis of the Expansin Gene BdEXP1 from Migration Plant parasitic Nematode (Bursaphelenchus doui)
Published 2025-04-01“…The BdEXP1 protein had the highest sequence similarity (64%) with the homologous protein of B. xylophilus, and contained a typical DPBB_SPI-like conservative domain and a signal peptide but no transmembrane structure, indicating that it was a secretory protein. …”
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51965
Regional variability in the projected changes in sub-daily precipitation IDF curves across the contiguous United States
Published 2025-01-01“…Currently constructed based on past data, IDF curves do not reflect the potential impacts of current and future changes in the hydrologic system, potentially leading to over- or under-design of structures. …”
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51966
Lipitension and cardiometabolic risk factors in young people
Published 2024-05-01“…In patients with lipitension, 43,8% were diagnosed with HTN, while the remaining 56,2% had BP ≥130/85 mm Hg. In the structure of dyslipidemia in lipitension, 79,2% had abnormalities in ≥2 lipid parameters, of which increased levels of low-density lipoprotein cholesterol (LDL-C) and hypercholesterolemia (78,3%) were most often detected. …”
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51967
Hydroxyurea blunts mitochondrial energy metabolism and osteoblast and osteoclast differentiation exacerbating trabecular bone loss in sickle cell mice
Published 2024-12-01“…To investigate HU action on SCD-related vertebral defects, we used HU-treated “Townes” mice, an SCD animal model and performed high-resolution micro-computed tomography (µCT) imaging to resolve bone volume and micro-architectural structure of cortical and trabecular bone, the two major compartments contributing to bone mass and strength. …”
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51968
In silico and in vivo Study of the Anti-Inflammatory Activity of Azomethine Derivatives of 2-amino-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxamide and 2-substituted 5,6,7,8-tetra...
Published 2025-02-01“…In silico prediction of anti-inflammatory activity was performed using the AutoDock 4.0 program. The virtual structures of the test compounds were constructed in HyperChem 8.0.4. …”
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51969
Mental health and life satisfaction of university students influenced by war
Published 2024-12-01“…These methods should be comprehensive and involve the integration of psychological support into the structure of universities, including individual and group counselling, crisis intervention, psychological training, and student support programmes.…”
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51970
Econometric predictive model for assessing the functional state of students during the examination period: a cross-sectional exploratory pilot study
Published 2023-10-01“…Mathematical modeling is widely used in medicine to analyze the body systems in terms of their structure, work and interrelations. The present study investigates factors associated with the adaptation potential of the cardiovascular system, develops multiple regression models for the dependence of the adaptive potential on these factors, and compares the significance of the linear model with non-linear ones. …”
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51971
The Role of Premorbid Background in Tanatogenesis of Acute Poisonings with Psychoactive Drugs in Gerontological Patients
Published 2018-11-01“…Background Human aging is a universal and regular process characterized by uneven and steady progression, inevitably affecting to some extent all levels of biological organization. In the structure of acute exotoxicosis, patients of gerontological age range from 10.3 to 12.9%. …”
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51972
Assessment of the quality of drinking water and basic water, sanitation, and hygiene conditions of urban street dwellers in Bangladesh
Published 2025-03-01“…A survey was conducted using a semi structure questionnaire to collect data on demographic characteristics, WASH situation and health problems. …”
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51973
Evaluation of the feasibility, appropriateness, and acceptability of an environmental cleaning program improvement toolkit at a tertiary care hospital in Nigeria
Published 2025-04-01“…A deductive analytic process was used to code and analyze interview data based on constructs of appropriateness and acceptability. …”
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51974
Behavioral tests for the assessment of social hierarchy in mice
Published 2025-03-01“…Future research may also benefit from integrating physiological data (e.g., hormone levels) to gain deeper insights into the relationships between social status, stress regulation, and mental health. …”
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51975
Genome-wide identification of invertase genes in sweetpotato and its response to nitrogen and planting densities
Published 2025-03-01“…Transcriptome data revealed that IbCIN2 and IbVIN3 were highly expressed in fibrous root (FR) and potential storage root (PSR), while IbVIN4 exhibited high expression levels in storage roots (SR), and IbCWIN2 was highly expressed in both FR and SR. …”
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51976
Antitumor efficiency of contact radiotherapy in combination with a chlorin-based photosensitizer in experiment
Published 2021-08-01“…Systemic administration of chlorin-based PS before the CRT session increases the antitumor efficacy of radiation therapy in animals with transplantable tumors of different histological structure and growth patterns. The data obtained indicate that further studies of the radiosensitizing properties of PS are promising.…”
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51977
Identifying populations at high risk of malaria: a mixed-methods case–control study to inform targeted interventions in Senegal
Published 2024-12-01“…Consultations with the National Malaria Control Programme (NMCP) and a review of available data identified nomadic pastoralists, gold miners, and Koranic school students as potential high-risk populations (HRPs). …”
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51978
Microascus microspora sp. nov. and Tolypocladium terrae sp. nov.; Two Novel Fungal Species Isolated from Soil in Korea
Published 2025-05-01“…Detailed descriptions, illustrations, and phylogenetic data are provided to support the recognition of these new species.…”
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51979
PCA Weight Determination-Based InSAR Baseline Optimization Method: A Case Study of the HaiKou Phosphate Mining Area in Kunming, Yunnan Province, China
Published 2025-06-01“…Additionally, the GACOS (Generic Atmospheric Correction Online Service) atmospheric correction product is applied to further enhance data quality. Taking the Haikou Phosphate Mine area in Kunming, Yunnan, as the study area, surface deformation information was extracted using the SBAS-InSAR technique, and the spatiotemporal characteristics of subsidence were analyzed. …”
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51980
Current Framework of Italian Agriculture and Changes between the 2010 and 2020 Censuses
Published 2024-09-01“…Farms’ type of activities, structure, digitalization/computerization, innovation, and workforces’ characteristics were analyzed. …”
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