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201
A new low-rank adaptation method for brain structure and metastasis segmentation via decoupled principal weight direction and magnitude
Published 2025-07-01“…Abstract Deep learning techniques have become pivotal in medical image segmentation, but their success often relies on large, manually annotated datasets, which are expensive and labor-intensive to obtain. …”
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202
From intensive care monitors to cloud environments: a structured data pipeline for advanced clinical decision supportResearch in context
Published 2025-01-01“…Here, we showcase a successful example of a data pipeline to efficiently move patient data to the cloud environment for structured storage. This supports individual patient analysis, enables largescale retrospective research, and the development of data-driven algorithms. …”
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203
Identifying long-term conditions in New Zealand general practice using structured and unstructured data: a cross-sectional study
Published 2025-05-01“…Incorporating free text increased LTC prevalence from 42.1% to 46.3%, reducing misclassification of MM diagnoses by identifying 12 626 additional patients with MM and 15 972 additional patients with at least one LTC.Discussion In the course of workflow, general practitioners face barriers to accurate LTC coding or may simply annotate with text-based descriptions. Programmatic text classification has demonstrated high performance and identified many more patients receiving LTC care.Conclusions Combining structured and unstructured data optimises MM detection in NZ general practices and has the potential to improve case management, follow-up care and allocation of healthcare resources.…”
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204
In-Silico Approaches for Molecular Characterization, Structural Function Prediction and Peptide Toxicity Analysis of the Matrix Protein of Vesicular stomatitis Indiana Virus (VSIV)
Published 2025-01-01“…Through In silico approach the physicochemical properties secondary and tertiary structures and functional annotations of the matrix protein are analyzed, results indicate that the VSIV matrix protein is dominated by alpha-helical regions with a consistent tertiary structure validated by quality assessment methods. …”
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205
A Bioinformatic Approach for Molecular Characterization and Functional Annotation of an Uncharacterized Protein from <i>Vibrio cholerae</i>
Published 2023-05-01“…Therefore, it is essential to comprehend <i>V. cholerae</i> by analyzing the structure and annotating the function of uncharacterized proteins. …”
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A hybrid YOLO-UNet3D framework for automated protein particle annotation in Cryo-ET images
Published 2025-07-01“…However, automated annotation of these macromolecular assemblies remains challenging due to low signal-to-noise ratios, missing wedge artifacts, heterogeneous backgrounds, and structural diversity. …”
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Mensch und Maschine als Team. Exploratives Topic Modeling und manuelle Annotation in der qualitativen Sozialforschung
Published 2024-05-01“…In an experimental setting, the interplay of topic modeling and grounded theory annotation in the exploitation of large-scale collections of qualitative research data is approached via a combination of quantitative pre-structuring and qualitative in-depth analysis. …”
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210
Long read whole genome sequencing-based discovery of structural variants and their role in aetiology of non-syndromic autism spectrum disorder in India
Published 2025-08-01“…Abstract Background Despite having heritability estimates of 80%, ~ 50% cases of autism spectrum disorders (ASD) remain without a genetic diagnosis. Structural variants (SVs) detected using long-read whole genome sequencing (lrWGS) are a relatively new class of variants implicated in neurodevelopmental disorders. …”
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211
NeuroTIS+: An Improved Method for Translation Initiation Site Prediction in Full-Length mRNA Sequence via Primary Structural Information
Published 2025-07-01“…However, this method has limitations in fully exploiting the primary structural information within mRNA sequences. First, it only captures label dependency within three neighboring codon labels. …”
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212
Inverted repeats dynamics shape Asclepiadoideae (Apocynaceae) Chloroplast genomes: effects on genome size, gene content, structural arrangement, and mutation rate
Published 2025-07-01“…The 160,494 base pairs (bp) long genome of Pentatropis nivalis exhibited a typical quadripartite structure, comprising a large single-copy (LSC) region of 91,508 bp and a small single-copy (SSC) region of 19,384 bp, separated by two IRs of 24,801 bp each. …”
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Unraveling the mitochondrial genome of the medicinal Chinese motherwort (Leonurus japonicus, Lamiaceae): structural dynamics, organelle-to-nuclear gene transfer, and evolutionary i...
Published 2025-06-01“…Elucidating mitogenomic structure and evolution can inform plant genetics, phylogenetics, and molecular breeding.MethodsWe assembled the complete mitochondrial genome of L. japonicus using a combination of Oxford Nanopore long reads and Illumina short reads. …”
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215
Maximizing science communication skills in a primary scientific literature-based cancer biology course: practical implementation methods
Published 2025-08-01“…The course utilized Hypothes.is web-based annotations, methods presentations, figure annotations, and structured discussions to promote active engagement with the literature. …”
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216
Spatial Variation in Coral Diversity and Reef Complexity in the Galápagos: Insights from Underwater Photogrammetry and New Data Extraction Methods
Published 2025-05-01“…We surveyed seven reef sites across the archipelago using underwater photogrammetry and developed new methods for 3D annotation and fractal dimension calculation. Our findings reveal variation in coral cover, diversity, and structural complexity across the archipelago. …”
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217
Biomedical Scholarly Article Editing and Sharing using Holistic Semantic Uplifting Approach
Published 2022-05-01“…We have developed a lightweight technical infrastructure (goSemantically) and miniaturized that as Google Docs add-ons that helps authors to add machine-interpretable metadata at the content and structural levels while authoring biomedical content. …”
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218
Spin-orbit interaction in quasi-monochromatic singular beams
Published 2024-02-01Get full text
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219
RoofMapNet: Utilizing geometric primitives for depicting planar building roof structure from high-resolution remote sensing imagery
Published 2025-07-01“…Additionally, to comprehensively evaluate the performance of roof structure detection models, we meticulously annotated a diverse, large-scale remote sensing imagery dataset for roof structure extraction, named RoofMapSet. …”
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220
Complete sequencing of the mitochondrial genome of tea plant Camellia sinensis cv. ‘Baihaozao’: multichromosomal structure, phylogenetic relationships, and adaptive evolutionary an...
Published 2025-06-01“…It systematically unveils its multi-chromosomal structure, RNA editing patterns, and adaptive evolutionary mechanisms, providing critical theoretical insights into the structural complexity and evolutionary mechanisms of the tea plant mitochondrial genome.MethodsThe mitochondrial genome was fully analyzed using genome sequencing and annotation techniques. …”
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