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    Expanding kinetoplastid genome annotation through protein structure comparison. by Juan Manuel Trinidad-Barnech, José Sotelo-Silveira, Darío Fernández Do Porto, Pablo Smircich

    Published 2025-04-01
    “…Our pipeline enabled the assignment of structural similarity to a substantial portion of kinetoplastid proteins, improving current knowledge through annotation transfer. …”
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    LCRAnnotationsDB: a database of low complexity regions functional and structural annotations by Joanna Ziemska-Legiecka, Patryk Jarnot, Sylwia Szymańska, Dagmara Błaszczyk, Alicja Staśczak, Hanna Langer-Macioł, Kinga Lucińska, Karolina Widzisz, Aleksandra Janas, Hanna Słowik, Wiktoria Śliwińska, Aleksandra Gruca, Marcin Grynberg

    Published 2024-12-01
    “…LCRAnnotationsDB aims to consolidate knowledge about LCRs and store relevant annotations in a single place. To unify redundant annotations, we assigned them categories based on similarity in function, protein structure, and biological process. …”
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    Improved enzyme functional annotation prediction using contrastive learning with structural inference by Yuxin Yang, Abby Jerger, Song Feng, Zixu Wang, Christina Brasfield, Margaret S. Cheung, Jeremy Zucker, Qiang Guan

    Published 2024-12-01
    “…However, the majority of these methods have primarily focused on either amino acid sequence data or protein structure data, neglecting the potential synergy of combining both modalities. …”
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    An open-source platform for structured annotation and computational workflows in digital pathology research by Luca Lianas, Mauro Del Rio, Luca Pireddu, Oskar Aspegren, Francesca Giunchi, Michelangelo Fiorentino, Simone Leo, Renata Zelic, Per Henrik Vincent, Nicolas Destefanis, Daniela Zugna, Lorenzo Richiardi, Andreas Pettersson, Olof Akre, Francesca Frexia

    Published 2025-08-01
    “…Its main features include: (1) structured, multi-label morphological and clinical image annotation; (2) support for controlled but customisable annotation protocols; (3) dedicated annotation tools to facilitate enhanced accuracy, efficiency and consistency in the annotation process; and (4) workflow-based computational analysis with integrated provenance tracking. …”
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    Cross-Modal Weakly Supervised RGB-D Salient Object Detection with a Focus on Filamentary Structures by Yifan Ding, Weiwei Chen, Guomin Zhang, Zhaoming Feng, Xuan Li

    Published 2025-05-01
    “…Current weakly supervised salient object detection (SOD) methods for RGB-D images mostly rely on image-level labels and sparse annotations, which makes it difficult to completely contour object boundaries in complex scenes, especially when detecting objects with filamentary structures. …”
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    AI-Powered Synthesis of Structured Multimodal Breast Ultrasound Reports Integrating Radiologist Annotations and Deep Learning Analysis by Khadija Azhar, Byoung-Dai Lee, Shi Sub Byon, Kyu Ran Cho, Sung Eun Song

    Published 2024-09-01
    “…Key modules in our method include image classification using visual features (ICVF), type classification via deep learning (TCDL), and automatic report structuring and compilation (ARSC). Experiments showed that the proposed method reduced the average report generation time to 3.8 min compared to manual processes, even when using relatively low-spec hardware. …”
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    Pangenome-scale annotation of mycobacteriophages for dissecting phage–host interactions based on a sequence clustering and structural homology analysis strategy by Xiao Guo, Zheng-Guo He

    Published 2025-08-01
    “…Mycobacteriophages constitute the largest genome-sequenced phage group; however, the vast majority of these phage proteins have not yet been effectively annotated. In this study, we employed a structure-based similarity search approach to improve protein annotation. …”
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    The golden genome annotation of Ganoderma lingzhi reveals a more complex scenario of eukaryotic gene structure and transcription activity by Lining Wang, Peiqi Shi, Zhaohua Ping, Qinghua Huang, Liqun Jiang, Nianfang Ma, Qingfu Wang, Jiang Xu, Yajie Zou, Zhihai Huang

    Published 2024-11-01
    “…However, accumulating evidence suggests a more complex landscape of gene structure and transcription. Ganoderma lingzhi, a model medicinal fungus, currently lacks high-quality genome annotation, hindering genetic studies. …”
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