Transcriptomic profiles of monocyte-derived macrophages exposed to SARS-CoV-2 VOCs reveal immune-evasion escape driven by delta by Alessia Gallo, Josè Camilla Sammartino, Roberta Vazzana, Roberto Giambruno, Claudia Carcione, Nicola Cuscino, Salvatore Castelbuono, Vitale Miceli, Matteo Bulati, Daniele Lilleri, Irene Cassaniti, Pier Giulio Conaldi, Fausto Baldanti

“…The success of each VOC, as well as the virus fitness, were enabled by altered intrinsic functional properties and, reasonably, to virus antigenicity changes, conferring the ability to evade a primed immune response. …”
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Numerical Simulation of Hybrid Electric–Structural Control for Microdroplet Formation in Ribbed T-Junction Microchannels by Ruyi Fu

“…A new empirical correlation is proposed to predict droplet size <inline-formula><math xmlns="http://www.w3.org/1998/Math/MathML" display="inline"><semantics><mrow><mi>S</mi><mo>/</mo><msubsup><mi>w</mi><mi>c</mi><mn>2</mn></msubsup></mrow></semantics></math></inline-formula> as a function of rib height <inline-formula><math xmlns="http://www.w3.org/1998/Math/MathML" display="inline"><semantics><mrow><mi>a</mi><mo>/</mo><msub><mi>w</mi><mi>c</mi></msub></mrow></semantics></math></inline-formula> and two-phase flow rate ratio <inline-formula><math xmlns="http://www.w3.org/1998/Math/MathML" display="inline"><semantics><mrow><msub><mi>Q</mi><mi>d</mi></msub><mo>/</mo><msub><mi>Q</mi><mi>c</mi></msub></mrow></semantics></math></inline-formula>: <inline-formula><math xmlns="http://www.w3.org/1998/Math/MathML" display="inline"><semantics><mrow><mi>S</mi><mo>/</mo><msubsup><mi>w</mi><mi>c</mi><mn>2</mn></msubsup><mo>=</mo><mrow><mo>(</mo><mo>−</mo><mn>0.62</mn><mo>−</mo><mn>1.8</mn><msub><mi>Q</mi><mi>d</mi></msub><mo>/</mo><msub><mi>Q</mi><mi>c</mi></msub><mo>)</mo></mrow><mrow><mo>(</mo><mi>a</mi><mo>/</mo><mi>w</mi><mo>)</mo></mrow><mrow><mo>+</mo><mo>(</mo><mn>0.64</mn><mo>+</mo><mn>0.99</mn></mrow><msub><mi>Q</mi><mi>d</mi></msub><mo>/</mo><msub><mi>Q</mi><mi>c</mi></msub><mo>)</mo></mrow></semantics></math></inline-formula>.…”
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Aldo-keto Reductase 1B10 (AKR1B10) Suppresses Sensitivity of Ferroptosis in TNBC by Activating the AKT/GSK3β/Nrf2/GPX4 Axis by Shanli Wu, Gun Yang, Xiaosha Wen, Yi Lin, Shenglong Wang, Jing Wang, Quan Liu, Dixian Luo

“…Several studies have highlighted the essential function of AKR1B10 in lipid metabolism and in the detoxification of lipid peroxides. …”
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Sistema de detección de señales de tráfico para la localización de intersecciones viales y frenado anticipado by Gabriel Villalón-Sepúlveda, Miguel Torres-Torriti, Marco Flores-Calero

“…The method is based on segmentation by color on the RGB-normalized space (ErEgEb) for generating regions of interest (ROIs), the classification of the type of signal using YCbCr and ErEgEb spaces to build a statistical template, where to remove the background has proposed a probability distribution function that models the color of the objects of interest and its background. …”
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Evaluation of Southern African wild edible plants for potential herb-drug interactions through ex vivo p-glycoprotein and in vitro cytochrome P450 3A4 inhibitory effects by P.S. Kheoane, K.C. Mokhetho, S. Mokhele, K.C. Mbara, C.M. Leonard, T.H. Gadaga, C. Tarirai

“…The herb/food-drug interactions also present opportunities for discovery of new functional excipients for enhancing the permeability of poorly absorbed orally administered drugs that are substrates of P-gp and CYP3A4.…”
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Abundancia y biomasa de macroinvertebrados edáficos en la temporada lluviosa, en tres usos de la tierra, en los Andes colombianos by Pardo Luis C

“…Results indicated that the environmental response of these organisms in terms of population and biomass is more associated to agroecosystem structure than to chemical, physical, or microbiological variation of the habitat. Functional groups should be taxonomically differentiated and samplings should be extended to the dry season. &#13; &#13; Key words: land use, soil macroinvertebrates, density, agroecosystems, Colombian Andes, biomass.…”
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Особливості інтеграції рослин в архітектуру у світових прикладах проектування житла by Serhii Buravchenko, Oleksandr Pyvovarov, Liliia Bezpala

“…The world tendencies of the combination of housing function and cultivation of gardening, care for it and influence on the environment are analyzed. …”
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The CD163 + tissue-infiltrating macrophages regulate ferroptosis in thyroid-associated ophthalmopathy orbital fibroblasts via the TGF-β/Smad2/3 signaling pathway by Xuemei Li, Siyi Wang, Hanwen Cao, Simin Xu, Chao Xiong, Jinhai Yu, Yunxiu Chen, Zhangjun Ren, Min Li, Ying Hu, Puying Gan, Qihua Xu, Yaohua Wang, Hongfei Liao

“…Abstract Background Thyroid-associated ophthalmopathy (TAO) is a thyroid function-related, organ-specific autoimmune disease that primarily leads to specific reactive changes and tissue remodeling in the periocular region. …”
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hUC-MSCs and derived exosomes attenuate DEX-induced muscle atrophy through modulation of estrogen signaling pathway by Na Li, Xiaoqin Liu, Qiong Wang, Yushu Chen, Chao Han, Chao Qu, Xin Guan, Wei Zou, Xiaomin Wang, Ang Li, Yin Zhang, Liping Zhu, Ruoyutong Du, Jing Liu, Yanfu Wang

“…Abstract Background Sarcopenia, a multifactorial syndrome characterized by progressive loss of skeletal muscle mass and strength, combined with impaired physical function, is associated primarily with aging but also driven by chronic inflammation, immobility, and endocrine dysregulation. …”
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Engineering safe anti-CD19-CD28ζ CAR T cells with CD8a hinge domain in serum-free media for adoptive immunotherapy by Muthuganesh Muthuvel, Muthuganesh Muthuvel, Thamizhselvi Ganapathy, Trent Spencer, Sunil S. Raikar, Saravanabhavan Thangavel, Alok Srivastava, Alok Srivastava, Alok Srivastava, Sunil Martin

“…The CAR-T cells expanded (148.4 ± 29 fold; n=7) in serum free media with very high viability (87.8 ± 2.2%; n=7) on day 12. The antitumor functions of CD19 CAR T cells as gauged against percentage lysis of NALM6 cells at a 1:1 ratio is 27.68 ± 6.87% drawing up to the release criteria. …”
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The Combined Effect of Garlic (Allium sativum) and Turmeric (Curcuma longa) Extracts to Reduce the Adverse Effects of Aflatoxin B1 in Rats by Hadi Sarir, Saeedeh Zakerian, masood didarkhah

“…The use of garlic, turmeric extract, and their combination improves liver function indicators and reduces liver enzymes such as AST, ALT, ALP, and total bilirubin. …”
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Facial Nerve Injury after Extracapsular Dissection for Benign Parotid Tumors with and without Intraoperative Monitoring: A Retrospective Study of a Single Center by Maria Giulia Cristofaro, Walter Colangeli, Francesco Ferragina, Giuseppe Tarallo, Angelo Ruggero Sottile, Maria Grazia Ioppolo, Antonella Arrotta, Ida Barca

“…Group 2 employed the Nerve Integrity Monitor (Medtronic’s NIM^®). To classify the FN function, we employed the modified House–Brackmann classification system. …”
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Molecular Cloning and Expression Characteristics of otx2 and eya1 During the Early Development of Seriola aureovittata by Yan JIANG, Xin LIU, Yongjiang XU, Aijun CUI, Bin WANG, Xinfu LIU, Xuezhou LIU, Zhiyong XUE

“…This study provides a molecular basis for understanding the physiological functions of otx2 and eya1 during the development of sensory organs and the regulatory mechanisms in yellowtail kingfish.…”
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Análisis y modelado de una estructura sensorial ultrasónica MIMO basado en M-CSS y técnicas de correlación by Alberto Ochoa, Jesús Ureña, Álvaro Hernández, Apolinar González, Walter Mata, Ramón A. Félix

“…This processing algorithm employs a pseudorandom macro-sequence obtained from a complementary set of M sequences (M- CSS) which, by auto-correlation and cross-correlation functions, the impulse responses from environment are obtained. …”
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Catalase Activity in the Brain Is Associated with Recovery from Brain Injury in a Piglet Model of Traumatic Brain Injury by Stephanie T. Dubrof, Sarah L. Schantz, Taylor H. LePage, Sydney E. Sneed, Savannah R. Cheek, Holly A. Kinder, Kylee J. Duberstein, David A. DeWahl, Jerry O. Stern, Alexander B. Baguisi, Erin E. Kaiser, Franklin D. West, Hea Jin Park

“…Oxidative stress significantly exacerbates primary TBI, leading to increased levels of intracerebral cell death, tissue loss, and long-term functional deficits in surviving patients. Catalase and superoxide dismutase (SOD) mitigate oxidative stress and play a critical role in dampening injury severity. …”
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Lipid metabolism-related inflammatory indices (LMIIs) and incident peripheral artery diseases (PAD) in patients with type 2 diabetes mellitus (T2DM): a multicohort study from China... by Yingying Wang, Qijing Jiang, Xiaoyan Li, Bichen Ren, Bingzhe Li, Hao Li, Yuan Fang, Zhihui Dong, Lihong Huang

“…Mediation effects of liver and kidney function-related indicators on associations between LMIIs and incident PAD were also explored. …”
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Saline–Alkali Tolerance Evaluation of Giant Reed (<i>Arundo donax</i>) Genotypes Under Saline–Alkali Stress at Seedling Stage by Yangxing Cai, Xiuming Cao, Bin Liu, Hui Lin, Hailing Luo, Fengshan Liu, Dewei Su, Shi Lv, Zhanxi Lin, Dongmei Lin

“…The saline–alkali tolerance of <i>A. donax</i> seedlings was comprehensively evaluated using principal component analysis and membership function analysis based on 15 parameters. The results indicate that P_n, T_r and G_s are effective physiological indicators for assessing saline–alkali tolerance of <i>A. donax</i> seedlings. …”
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New approaches to diagnosis and management of patients with metabolic-associated steatotic liver disease with immune response to SARS-CоV-2 by V.I. Didenko, S.L. Melanich, I.A. Klenina, O.M. Tatarchuk, O.P. Petishko, H.I. Bocharov

“…All patients’ serum parameters of immunological profile, liver function, and prothrombotic environment were determined. …”
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Characteristics of positive and negative effects on the quality of life of breast cancer patients by Jin Zhao, De-Shuang Yang, Yi-Qi Liu, Yan-Kun Wu, Chao Chen, Ji-Tao Li, Ren-Gang Wu

“…Patients were excluded from the study if they (1) had severe comorbid conditions causing functional impairment or life-threatening risks or (2) suffered from mental disorders or were unconscious at the time of the study. …”
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Clinical study of mild hypothermia therapy after endovascular mechanical thrombectomy for acute anterior circulation massive cerebral infarction by ZHANG Jia⁃qi, LIU Yang, SHI Yi, REN Zhi⁃qiang, HAN Bing⁃sha, FENG Guang

“…Results The serum NSE level at 72 h after operation in the hypothermia group was lower than the mechanical thrombectomy group [18.86 (13.35, 30.54) μg/L vs. 21.43 (18.30, 32.90) μg/L; Z = ⁃ 2.147, P = 0.032], and the good prognosis rate at 3 months after discharge was higher than the mechanical thrombectomy group [46.34% (19/41) vs. 21.95% (9/41); χ2 = 5.423, P = 0.020], and the mortality rate (χ2 = 0.734, P = 0.391), incidence of hemorrhagic transformation (χ2 = 0.497, P = 0.481), vascular reocclusion (χ2 = 0.945, P = 0.331), malignant brain edema (χ2 = 1.058, P = 0.304), pulmonary infection (χ2 = 2.614, P = 0.106), electrolyte disturbance (χ2 = 1.222, P = 0.269), arrhythmia (χ2 = 0.456, P = 0.499), deep venous thrombosis (χ2 = 0.311, P = 0.577), and abnormal coagulation function (χ2 = 1.246, P = 0.264) during hospitalization between the 2 groups were not statistically significant. …”
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